Health Sciences Research

Research Output

Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome

Win, A. K., Lindor, N. M., Young, J. P., MacRae, F. A., Young, G. P., Williamson, E., Parry, S., Goldblatt, J., Lipton, L., Winship, I., Leggett, B., Tucker, K. M., Giles, G. G., Buchanan, D. D., Clendenning, M., Rosty, C., Arnold, J., Joan Levine, A., Haile, R. W., Gallinger, S. & 4 others, Marchand, L. L., Newcomb, P. A., Hopper, J. L. & Jenkins, M. A., Sep 19 2012, In : Journal of the National Cancer Institute. 104, 18, p. 1363-1372 10 p.

Research output: Contribution to journalArticle

134 Scopus citations

Risks of lynch syndrome cancers for msh6 mutation carriers

Baglietto, L., Lindor, N. M., Dowty, J. G., White, D. M., Wagner, A., Gomez Garcia, E. B., Vriends, A. H. J. T., Cartwright, N. R., Barnetson, R. A., Farrington, S. M., Tenesa, A., Hampel, H., Buchanan, D., Arnold, S., Young, J., Walsh, M. D., Jass, J., MacRae, F., Antill, Y., Winship, I. M. & 19 others, Giles, G. G., Goldblatt, J., Parry, S., Suthers, G., Leggett, B., Butz, M., Aronson, M., Poynter, J. N., Baron, J. A., Le Marchand, L., Haile, R., Gallinger, S., Hopper, J. L., Potter, J., De La Chapelle, A., Vasen, H. F., Dunlop, M. G., Thibodeau, S. N. & Jenkins, M. A., Feb 2010, In : Journal of the National Cancer Institute. 102, 3, p. 193-201 9 p.

Research output: Contribution to journalArticle

228 Scopus citations

Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families

Choi, Y. H., Lakhal-Chaieb, L., Kröl, A., Yu, B., Buchanan, D., Ahnen, D., Le Marchand, L., Newcomb, P. A., Win, A. K., Jenkins, M., Lindor, N. M. & Briollais, L., Jul 1 2019, In : Journal of the National Cancer Institute. 111, 7, p. 675-683 9 p., djy159.

Research output: Contribution to journalArticle

2 Scopus citations

Risks of colorectal and other cancers after endometrial cancer for women with lynch syndrome

Win, A. K., Lindor, N. M., Winship, I., Tucker, K. M., Buchanan, D. D., Young, J. P., Rosty, C., Leggett, B., Giles, G. G., Goldblatt, J., MacRae, F. A., Parry, S., Kalady, M. F., Baron, J. A., Ahnen, D. J., Marchand, L. L., Gallinger, S., Haile, R. W., Newcomb, P. A., Hopper, J. L. & 1 others, Jenkins, M. A., Feb 20 2013, In : Journal of the National Cancer Institute. 105, 4, p. 274-279 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Risk of subsequent malignancies in survivors of childhood leukemia

Perkins, S. M., DeWees, T., Shinohara, E. T., Reddy, M. M. & Frangoul, H., Dec 1 2013, In : Journal of Cancer Survivorship. 7, 4, p. 544-550 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Risk of Recurrence and 10-Year Outcomes in Surgically Treated Nonmelanoma Skin Cancer in Cardiac and Liver Transplant Recipients

Yu, N. Y., Dewees, T. A., Alam, M., Ochoa, S. A., Mangold, A. R., Steidley, D. E., Vargas, H. E., Golafshar, M. A., Schild, S. E., Halyard, M. Y. & Patel, S. H., 2020, (Accepted/In press) In : American Journal of Clinical Oncology: Cancer Clinical Trials. 00003.

Research output: Contribution to journalArticle

Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers

Win, A. K., Parry, S., Parry, B., Kalady, M. F., Macrae, F. A., Ahnen, D. J., Young, G. P., Lipton, L., Winship, I., Boussioutas, A., Young, J. P., Buchanan, D. D., Arnold, J., Le Marchand, L., Newcomb, P. A., Haile, R. W., Lindor, N. M., Gallinger, S., Hopper, J. L. & Jenkins, M. A., Jun 1 2013, In : Annals of surgical oncology. 20, 6, p. 1829-1836 8 p.

Research output: Contribution to journalArticle

68 Scopus citations

Risk of Lower and upper gastrointestinal bleeding, transfusions, and hospitalizations with complex antithrombotic therapy in elderly patients

Abraham, N. S., Hartman, C., Richardson, P., Castillo, D., Street, R. L. & Naik, A. D., Oct 22 2013, In : Circulation. 128, 17, p. 1869-1877 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Risk of Gastrointestinal Bleeding Increases With Combinations of Antithrombotic Agents and Patient Age

Abraham, N. S., Noseworthy, P. A., Inselman, J., Herrin, J., Yao, X., Sangaralingham, L. R., Cornish, G., Ngufor, C. & Shah, N. D., Feb 2020, In : Clinical Gastroenterology and Hepatology. 18, 2, p. 337-346.e19

Research output: Contribution to journalArticle

4 Scopus citations

Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH

Win, A. K., Reece, J. C., Dowty, J. G., Buchanan, D. D., Clendenning, M., Rosty, C., Southey, M. C., Young, J. P., Cleary, S. P., Kim, H., Cotterchio, M., Macrae, F. A., Tucker, K. M., Baron, J. A., Burnett, T., Le Marchand, L., Casey, G., Haile, R. W., Newcomb, P. A., Thibodeau, S. N. & 5 others, Hopper, J. L., Gallinger, S., Winship, I. M., Lindor, N. M. & Jenkins, M. A., Oct 1 2016, In : International Journal of Cancer. 139, 7, p. 1557-1563 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Risk of endometrial cancer for women diagnosed with HNPCC-related colorectal carcinoma

Obermair, A., Youlden, D. R., Young, J. P., Lindor, N. M., Baron, J. A., Newcomb, P., Parry, S., Hopper, J. L., Haile, R. & Jenkins, M. A., Dec 1 2010, In : International Journal of Cancer. 127, 11, p. 2678-2684 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene

Win, A. K., Reece, J. C., Buchanan, D. D., Clendenning, M., Young, J. P., Cleary, S. P., Kim, H., Cotterchio, M., Dowty, J. G., MacInnis, R. J., Tucker, K. M., Winship, I. M., Macrae, F. A., Burnett, T., Le Marchand, L., Casey, G., Haile, R. W., Newcomb, P. A., Thibodeau, S. N., Lindor, N. M. & 3 others, Hopper, J. L., Gallinger, S. & Jenkins, M. A., Jul 23 2015, In : Familial Cancer. 14, 4, p. 575-583 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer

Win, A. K., Dowty, J. G., Cleary, S. P., Kim, H., Buchanan, D. D., Young, J. P., Clendenning, M., Rosty, C., Macinnis, R. J., Giles, G. G., Boussioutas, A., Macrae, F. A., Parry, S., Goldblatt, J., Baron, J. A., Burnett, T., Le Marchand, L., Newcomb, P. A., Haile, R. W., Hopper, J. L. & 6 others, Cotterchio, M., Gallinger, S., Lindor, N. M., Tucker, K. M., Winship, I. M. & Jenkins, M. A., May 2014, In : Gastroenterology. 146, 5, p. 1208-1211.e5

Research output: Contribution to journalArticle

81 Scopus citations

Risk of breast cancer in Lynch syndrome: A systematic review

Win, A. K., Lindor, N. M. & Jenkins, M. A., Mar 19 2013, In : Breast Cancer Research. 15, 2, R27.

Research output: Contribution to journalArticle

74 Scopus citations

Risk factors predicting positive margins at primary wide local excision of cutaneous melanoma

Mangold, A., Skinner, R., Dueck, A., Sekulic, A. D. & Pockaj, B. A., May 1 2016, In : Dermatologic Surgery. 42, 5, p. 646-652 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study

Jayasekara, H., Reece, J. C., Buchanan, D. D., Rosty, C., Ghazaleh Dashti, S., Ouakrim, D. A., Winship, I. M., MacRae, F. A., Boussioutas, A., Giles, G. G., Ahnen, D. J., Lowery, J., Casey, G., Haile, R. W., Gallinger, S., Le Marchand, L., Newcomb, P. A., Lindor, N. M., Hopper, J. L., Parry, S. & 2 others, Jenkins, M. A. & Win, A. K., Sep 1 2016, In : International Journal of Cancer. 139, 5, p. 1081-1090 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Risk factors for dementia with Lewy bodies A case-control study

Boot, B. P., Orr, C. F., Ahlskog, J. E., Ferman, T. J., Roberts, R., Pankratz, V. S., Dickson, D. W., Parisi, J., Aakre, J. A., Geda, Y. E., Knopman, D. S., Petersen, R. C. & Boeve, B. F., Aug 27 2013, In : Neurology. 81, 9, p. 833-840 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

Risk factors associated with local and in-transit recurrence of cutaneous melanoma

Stucky, C. C. H., Gray, R. J., Dueck, A. C., Wasif, N., Laman, S. D., Sekulic, A. & Pockaj, B. A., Dec 1 2010, In : American journal of surgery. 200, 6, p. 770-775 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Risk and protective factors for cognitive impairment in persons aged 85 years and older

Roberts, R. O., Cha, R. H., Mielke, M. M., Geda, Y. E., Boeve, B. F., Machulda, M. M., Knopman, D. S. & Petersen, R. C., May 5 2015, In : Neurology. 84, 18, p. 1854-1861 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

Umar, A., Boland, C. R., Terdiman, J. P., Syngal, S., de la Chapelle, A., Rüschoff, J., Fishel, R., Lindor, N. M., Burgart, L. J., Hamelin, R., Hamilton, S. R., Hiatt, R. A., Jass, J., Lindblom, A., Lynch, H. T., Peltomaki, P., Ramsey, S. D., Rodriguez-Bigas, M. A., Vasen, H. F. A., Hawk, E. T. & 3 others, Barrett, J. C., Freedman, A. N. & Srivastava, S., Feb 18 2004, In : Journal of the National Cancer Institute. 96, 4, p. 261-268 8 p.

Research output: Contribution to journalArticle

Open Access
2096 Scopus citations

Return of individual research results from genome-wide association studies: Experience of the Electronic Medical Records and Genomics (eMERGE) Network

Fullerton, S. M., Wolf, W. A., Brothers, K. B., Clayton, E. W., Crawford, D. C., Denny, J. C., Greenland, P., Koenig, B. A., Leppig, K. A., Lindor, N. M., McCarty, C. A., McGuire, A. L., McPeek Hinz, E. R., Mirel, D. B., Ramos, E. M., Ritchie, M. D., Smith, M. E., Waudby, C. J., Burke, W. & Jarvik, G. P., Apr 1 2012, In : Genetics in Medicine. 14, 4, p. 424-431 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

Returning results in the genomic era: Initial experiences of the emerge network

Wiesner, G. L., Rahm, A. K., Appelbaum, P., Aufox, S., Bland, S. T., Blout, C. L., Christensen, K. D., Chung, W. K., Clayton, E. W., Green, R. C., Harr, M. H., Henrikson, N., Hoell, C., Holm, I. A., Jarvik, G. P., Kullo, I. J., Lammers, P. E., Larson, E. B., Lindor, N. M., Marasa, M. & 12 others, Myers, M. F., Peterson, J. F., Prows, C. A., Ralston, J. D., Rasouly, H. M., Sharp, R. R., Smith, M. E., Van Driest, S. L., Williams, J. L., Williams, M. S., Wynn, J. & Leppig, K. A., May 2020, In : Journal of Personalized Medicine. 10, 2, 30.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Returning genomic results in a Federally Qualified Health Center: the intersection of precision medicine and social determinants of health

Shaibi, G. Q., Kullo, I. J., Singh, D. P., Hernandez, V., Sharp, R. R., Cuellar, I., De Filippis, E., Levey, S., Breitkopf, C. R., Mandarino, L. J., Yang, P., Thibodeau, S. N. & Lindor, N. M., Jan 1 2020, (Accepted/In press) In : Genetics in Medicine.

Research output: Contribution to journalArticle

1 Scopus citations

Returning a Research Participant's Genomic Results to Relatives: Analysis and Recommendations

Wolf, S. M., Branum, R., Koenig, B. A., Petersen, G. M., Berry, S. A., Beskow, L. M., Daly, M. B., Fernandez, C. V., Green, R. C., Leroy, B. S., Lindor, N. M., O'Rourke, P. P., Breitkopf, C. R., Rothstein, M. A., Van Ness, B. & Wilfond, B. S., Sep 1 2015, In : Journal of Law, Medicine and Ethics. 43, 3, p. 440-463 24 p.

Research output: Contribution to journalArticle

56 Scopus citations

Responsiveness of the smoking cessation quality of life (SCQoL) questionnaire

Shaw, J. W., Coons, S. J., Foster, S. A., Leischow, S. J. & Hays, R. D., Jan 1 2001, In : Clinical therapeutics. 23, 6, p. 957-969 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Response to ten Broeke and Nielsen

Lindor, N. M. & Goodenberger, M. L., Aug 6 2015, In : Genetics in Medicine. 17, 8, p. 684-685 2 p.

Research output: Contribution to journalArticle

Response Rate Following Albumin-Bound Paclitaxel Plus Gemcitabine Plus Cisplatin Treatment among Patients with Advanced Pancreatic Cancer: A Phase 1b/2 Pilot Clinical Trial

Jameson, G. S., Borazanci, E., Babiker, H. M., Poplin, E., Niewiarowska, A. A., Gordon, M. S., Barrett, M. T., Rosenthal, A., Stoll-D'astice, A., Crowley, J., Shemanski, L., Korn, R. L., Ansaldo, K., Lebron, L., Ramanathan, R. K. & Von Hoff, D. D., Jan 1 2019, (Accepted/In press) In : JAMA Oncology.

Research output: Contribution to journalArticle

6 Scopus citations

Response

Perez, E. A. & Dueck, A. C., Jun 20 2012, In : Journal of the National Cancer Institute. 104, 12, p. 958-959 2 p.

Research output: Contribution to journalLetter

Response

Acosta, R. D., Abraham, N. S. & Dewitt, J. M., Jun 1 2016, In : Gastrointestinal endoscopy. 83, 6, p. 1305-1306 2 p.

Research output: Contribution to journalLetter

Resolution of syncope with treatment of sleep apnea

Willis, F. B., Isley, A. L., Geda, Y. E., Quarles IV, L. & Fredrickson, P. A., Sep 2008, In : Journal of the American Board of Family Medicine. 21, 5, p. 466-468 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Resolution of neonatal hypertrophic cardiomyopathy in an infant with an affected mother

Eidem, B. W., Lindor, N. M. & Driscoll, D. J., May 1 1999, In : Pediatric Cardiology. 20, 3, p. 208-211 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Research priorities for fctc articles 20, 21, and 22: Surveillance/evaluation and information exchange

Giovino, G. A., Kulak, J. A., Kalsbeek, W. D. & Leischow, S. J., Apr 2013, In : Nicotine and Tobacco Research. 15, 4, p. 847-861 15 p., nts336.

Research output: Contribution to journalArticle

5 Scopus citations

Research priorities and infrastructure needs of the family smoking prevention and tobacco control act: Science to inform FDA policy

Leischow, S. J., Zeller, M. J. D. & Backinger, C. L., Jan 3 2012, In : Nicotine and Tobacco Research. 14, 1, p. 1-6 6 p.

Research output: Contribution to journalEditorial

15 Scopus citations

Research priorities, measures, and recommendations for assessment of tobacco use in clinical cancer research

Land, S. R., Toll, B. A., Moinpour, C. M., Mitchell, S. A., Ostroff, J. S., Hatsukami, D. K., Duffy, S. A., Gritz, E. R., Rigotti, N. A., Brandon, T. H., Prindiville, S. A., Sarna, L. P., Schnoll, R. A., Herbst, R. S., Cinciripini, P. M., Leischow, S. J., Dresler, C. M., Fiore, M. C. & Warren, G. W., Apr 15 2016, In : Clinical Cancer Research. 22, 8, p. 1907-1913 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Research collaboration in the discovery, development, and delivery networks of a statewide cancer coalition

Provan, K. G., Leischow, S. J., Keagy, J. & Nodora, J., Nov 1 2010, In : Evaluation and Program Planning. 33, 4, p. 349-355 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Reply to N. Magné et al

Halyard, M. Y., Pisansky, T. M., Dueck, A. C., Suman, V. J., Pierce, L. J., Solin, L. J., Marks, L. B., Davidson, N., Martino, S., Kaufman, P., Kutteh, L., Dakhil, S. & Perez, E. A., Dec 1 2009, In : Journal of Clinical Oncology. 27, 34, p. e240-e241

Research output: Contribution to journalLetter

Reply from the Editorialist

Geda, Y. E., Apr 26 2011, In : Neurology. 76, 17, p. 1531-1532 2 p.

Research output: Contribution to journalLetter

Relative intake of macronutrients impacts risk of mild cognitive impairment or dementia

Roberts, R. O., Roberts, L. A., Geda, Y. E., Cha, R. H., Pankratz, V. S., O'Connor, H. M., Knopman, D. S. & Petersen, R. C., 2012, In : Journal of Alzheimer's Disease. 32, 2, p. 329-339 11 p.

Research output: Contribution to journalArticle

66 Scopus citations

Relationship between smokers' modes of entry into quitlines and treatment outcomes

Guy, M. C., Seltzer, R. G. N., Cameron, M., Pugmire, J., Michael, S. & Leischow, S. J., Jan 2 2012, In : American Journal of Health Behavior. 36, 1, p. 3-11 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Relationship between inpatient hyperglycemia and insulin treatment after kidney transplantation and future new onset diabetes mellitus

Chakkera, H. A., Knowler, W. C., Devarapalli, Y., Weil, E. J., Heilman, R. L., Dueck, A., Mulligan, D. C., Reddy, K. S., Moss, A. A., Mekeel, K. L., Mazur, M. J., Hamawi, K., Castro, J. C. & Cook, C. B., Sep 1 2010, In : Clinical Journal of the American Society of Nephrology. 5, 9, p. 1669-1675 7 p.

Research output: Contribution to journalArticle

56 Scopus citations

Regulation of intercellular adhesion molecule-1 gene expression by tumor necrosis factor-α, interleukin-1β, and interferon-γ in astrocytes

Shrikant, P., Il Yup Chung, Y. C., Ballestas, M. E. & Benveniste, E. N., May 1994, In : Journal of neuroimmunology. 51, 2, p. 209-220 12 p.

Research output: Contribution to journalArticle

124 Scopus citations

Regulating mammalian target of rapamycin to tune vaccination-induced CD8 + T cell responses for tumor immunity

Li, Q., Rao, R., Vazzana, J., Goedegebuure, P., Odunsi, K., Gillanders, W. & Shrikant, P. A., Apr 1 2012, In : Journal of Immunology. 188, 7, p. 3080-3087 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

Regulating functional cell fates in CD8 T cells

Shrikant, P. A., Rao, R., Li, Q., Kesterson, J., Eppolito, C., Mischo, A. & Singhal, P., Mar 1 2010, In : Immunologic Research. 46, 1-3, p. 12-22 11 p.

Research output: Contribution to journalReview article

39 Scopus citations

Regional recurrence in the era of sentinel lymph node biopsy

Linnaus, M. E., Dueck, A., Kosiorek, H. E., Gray, R. J., Wasif, N., Northfelt, D. W., Anderson, K. S., McCullough, A. E., Wong, W. W., Halyard, M. Y., Patel, S. H. & Pockaj, B. A., Dec 1 2015, In : American Journal of Surgery. 210, 6, p. 1155-1161 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: A large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

ABCTB Investigators, EMBRACE Group, GENICA-Network, HEBON Group & KConFab investigators, Dec 23 2014, In : Breast Cancer Research. 16, 1, 3419.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations

Reevaluating the imaging definition of tumor progression: Perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival

Hu, L. S., Eschbacher, J. M., Heiserman, J. E., Dueck, A. C., Shapiro, W. R., Liu, S., Karis, J. P., Smith, K. A., Coons, S. W., Nakaji, P., Spetzler, R. F., Feuerstein, B. G., Debbins, J. & Baxter, L. C., Jul 2012, In : Neuro-oncology. 14, 7, p. 919-930 12 p.

Research output: Contribution to journalArticle

116 Scopus citations

Reducing tobacco harm: Research challenges and issues

Hatsukami, D. K., Slade, J., Benowitz, N. L., Giovino, G. A., Gritz, E. R., Leischow, S. & Warner, K. E., Jan 1 2002, In : Nicotine and Tobacco Research. 4, SUPPL. 2, p. S89-S101

Research output: Contribution to journalReview article

54 Scopus citations

Reducing the risk of requirements volatility: Findings from an empirical survey

Ferreira, S., Shunk, D., Collofello, J., MacKulak, G. & Dueck, A., Aug 1 2011, In : Journal of Software Maintenance and Evolution. 23, 5, p. 375-393 19 p.

Research output: Contribution to journalReview article

11 Scopus citations