Health Sciences Research

Research Output 1992 2020

2012

Memory disorders

Geda, Y. E., Cockerill, R. & Petersen, R. C., Mar 28 2012, Principles and Practice of Geriatric Psychiatry. Wolters Kluwer Health Adis (ESP), p. 605-625 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Memory Disorders
150 Citations (Scopus)

Meta-analysis of new genome-wide association studies of colorectal cancer risk

Peters, U., Hutter, C. M., Hsu, L., Schumacher, F. R., Conti, D. V., Carlson, C. S., Edlund, C. K., Haile, R. W., Gallinger, S., Zanke, B. W., Lemire, M., Rangrej, J., Vijayaraghavan, R., Chan, A. T., Hazra, A., Hunter, D. J., Ma, J., Fuchs, C. S., Giovannucci, E. L., Kraft, P. & 38 others, Liu, Y., Chen, L., Jiao, S., Makar, K. W., Taverna, D., Gruber, S. B., Rennert, G., Moreno, V., Ulrich, C. M., Woods, M. O., Green, R. C., Parfrey, P. S., Prentice, R. L., Kooperberg, C., Jackson, R. D., Lacroix, A. Z., Caan, B. J., Hayes, R. B., Berndt, S. I., Chanock, S. J., Schoen, R. E., Chang-Claude, J., Hoffmeister, M., Brenner, H., Frank, B., Bézieau, S., Küry, S., Slattery, M. L., Hopper, J. L., Jenkins, M. A., Le Marchand, L., Lindor, N. M., Newcomb, P. A., Seminara, D., Hudson, T. J., Duggan, D. J., Potter, J. D. & Casey, G., Feb 2012, In : Human Genetics. 131, 2, p. 217-234 18 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Meta-Analysis
Colorectal Neoplasms
Single Nucleotide Polymorphism
Developed Countries
15 Citations (Scopus)

Mild cognitive impairment: A subset of minor neurocognitive disorder?

Geda, Y. E. & Nedelska, Z., Oct 2012, In : American Journal of Geriatric Psychiatry. 20, 10, p. 821-826 6 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Biomarkers
Neuroimaging
Observational Studies
25 Citations (Scopus)

Mild cognitive impairment in older adults

Geda, Y. E., Aug 2012, In : Current Psychiatry Reports. 14, 4, p. 320-327 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Dementia
National Institute on Aging (U.S.)
Research
Neuroimaging
9 Citations (Scopus)

Multimodality therapy improves survival in elderly patients with locally advanced non-small cell lung cancer-A retrospective analysis

Paripati, H., Karlin, N. J., Schild, S. E., Vora, S. A., Dueck, A. & Ross, H. J., Apr 2012, In : Journal of Geriatric Oncology. 3, 2, p. 104-110 7 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Survival
Therapeutics
Age Groups
Combined Modality Therapy
3 Citations (Scopus)

Multiple jejunal cancers resulting from combination of germline APC and MLH1 mutations

Lindor, N. M., Smyrk, T. C., Buehler, S., Gunawardena, S. R., Thomas, B. C., Limburg, P. J., Kirmani, S. & Thibodeau, S. N., Dec 2012, In : Familial Cancer. 11, 4, p. 667-669 3 p.

Research output: Contribution to journalArticle

Jejunal Neoplasms
Heterozygote
Phenotype
Mutation
Adenomatous Polyposis Coli
12 Citations (Scopus)

Mutation screening of RAD51C in high-risk breast and ovarian cancer families

Lu, W., Wang, X., Lin, H., Lindor, N. M. & Couch, F. J., Sep 2012, In : Familial Cancer. 11, 3, p. 381-385 5 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Breast Neoplasms
Mutation
Penetrance
Genes
16 Citations (Scopus)

Mutations of SMAD4 account for both LAPS and Myhre syndromes

Lindor, N. M., Gunawardena, S. R. & Thibodeau, S. N., Jun 2012, In : American Journal of Medical Genetics, Part A. 158 A, 6, p. 1520-1521 2 p.

Research output: Contribution to journalArticle

Congenital Hand Deformities
Smad4 Protein
Growth Disorders
Cryptorchidism
Joint Diseases
190 Citations (Scopus)

Myeloproliferative neoplasm (MPN) symptom assessment form total symptom score: Prospective international assessment of an abbreviated symptom burden scoring system among patients with MPNs

Emanuel, R. M., Dueck, A., Geyer, H. L., Kiladjian, J. J., Slot, S., Zweegman, S., Te Boekhorst, P. A. W., Commandeur, S., Schouten, H. C., Sackmann, F., Fuentes, A. K., Hernández-Maraver, D., Pahl, H. L., Griesshammer, M., Stegelmann, F., Doehner, K., Lehmann, T., Bonatz, K., Reiter, A., Boyer, F. & 23 others, Etienne, G., Ianotto, J. C., Ranta, D., Roy, L., Cahn, J. Y., Harrison, C. N., Radia, D., Muxi, P., Maldonado, N., Besses, C., Cervantes, F., Johansson, P. L., Barbui, T., Barosi, G., Vannucchi, A. M., Passamonti, F., Andreasson, B., Ferarri, M. L., Rambaldi, A., Samuelsson, J., Birgegard, G., Tefferi, A. & Mesa, R. A., Nov 20 2012, In : Journal of Clinical Oncology. 30, 33, p. 4098-4103 6 p.

Research output: Contribution to journalArticle

Symptom Assessment
Neoplasms
Research Design
Quality of Life
Essential Thrombocythemia
13 Citations (Scopus)

North central cancer treatment group (NCCTG) N0537: Phase II trial of vegf-trap in patients with metastatic breast cancer previously treated with an anthracycline and/or a taxane

Sideras, K., Dueck, A., Hobday, T. J., Rowland, K. M., Allred, J. B., Northfelt, D. W., Lingle, W. L., Behrens, R. J., Fitch, T. R., Nikcevich, D. A. & Perez, E. A., Dec 2012, In : Clinical Breast Cancer. 12, 6, p. 387-391 5 p.

Research output: Contribution to journalArticle

Anthracyclines
Vascular Endothelial Growth Factor A
Breast Neoplasms
Disease-Free Survival
Neoplasms
26 Citations (Scopus)

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

OCGN, on behalf of the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA), SWE-BRCA, HEBON, EMBRACE, GEMO & KConFab, Apr 1 2012, In : Human Mutation. 33, 4, p. 690-702 13 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Alleles
Mutation
Germ-Line Mutation
Genome-Wide Association Study
259 Citations (Scopus)

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: Results from the consortium of investigators of modifiers of BRCA1/2 (CIMBA)

Mavaddat, N., Barrowdale, D., Andrulis, I. L., Domchek, S. M., Eccles, D., Nevanlinna, H., Ramus, S. J., Spurdle, A., Robson, M., Sherman, M. E., Mulligan, A. M., Couch, F. J., Engel, C., McGuffog, L., Healey, S., Sinilnikova, O. M., Southey, M. C., Terry, M. B., Goldgar, D., O'Malley, F. & 113 others, John, E. M., Janavicius, R., Tihomirova, L., Hansen, T. V. O., Nielsen, F. C., Osorio, A., Stavropoulou, A., Benítez, J., Manoukian, S., Peissel, B., Barile, M., Volorio, S., Pasini, B., Dolcetti, R., Putignano, A. L., Ottini, L., Radice, P., Hamann, U., Rashid, M. U., Hogervorst, F. B., Kriege, M., Van Der Luijt, R. B., Peock, S., Frost, D., Evans, D. G., Brewer, C., Walker, L., Rogers, M. T., Side, L. E., Houghton, C., Weaver, J., Godwin, A. K., Schmutzler, R. K., Wappenschmidt, B., Meindl, A., Kast, K., Arnold, N., Niederacher, D., Sutter, C., Deissler, H., Gadzicki, D., Preisler-Adams, S., Varon-Mateeva, R., Schönbuchner, I., Gevensleben, H., Stoppa-Lyonnet, D., Belotti, M., Barjhoux, L., Isaacs, C., Peshkin, B. N., Caldes, T., De Al Hoya, M., Cañadas, C., Heikkinen, T., Heikkilä, P., Aittomäki, K., Blanco, I., Lazaro, C., Brunet, J., Agnarsson, B. A., Arason, A., Barkardottir, R. B., Dumont, M., Simard, J., Montagna, M., Agata, S., D'Andrea, E., Yan, M., Fox, S., Rebbeck, T. R., Rubinstein, W., Tung, N., Garber, J. E., Wang, X., Fredericksen, Z., Pankratz, V. S., Lindor, N. M., Szabo, C., Offit, K., Sakr, R., Gaudet, M. M., Singer, C. F., Tea, M. K., Rappaport, C., Mai, P. L., Greene, M. H., Sokolenko, A., Imyanitov, E., Toland, A. E., Senter, L., Sweet, K., Thomassen, M., Gerdes, A. M., Kruse, T., Caligo, M., Aretini, P., Rantala, J., Von Wachenfeld, A., Henriksson, K., Steele, L., Neuhausen, S. L., Nussbaum, R., Beattie, M., Odunsi, K., Sucheston, L., Gayther, S. A., Nathanson, K., Gross, J., Walsh, C., Karlan, B., Chenevix-Trench, G., Easton, D. F. & Antoniou, A. C., Jan 2012, In : Cancer Epidemiology Biomarkers and Prevention. 21, 1, p. 134-147 14 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Ovarian Neoplasms
Research Personnel
Pathology
Breast Neoplasms
27 Citations (Scopus)

Performance of PREMM 1,2,6, MMRpredict, and MMRpro in detecting Lynch syndrome among endometrial cancer cases

Mercado, R. C., Hampel, H., Kastrinos, F., Steyerberg, E., Balmana, J., Stoffel, E., Cohn, D. E., Backes, F. J., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Casey, G., Haile, R., Madhavan, S., De La Chapelle, A. & Syngal, S., Jul 2012, In : Genetics in Medicine. 14, 7, p. 670-680 11 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Endometrial Neoplasms
Population
Area Under Curve
Sensitivity and Specificity
64 Citations (Scopus)

Predictability of adjuvant trastuzumab benefit in N9831 patients using the ASCO/CAP HER2-positivity criteria

Perez, E. A., Dueck, A., McCullough, A. E., Reinholz, M. M., Tenner, K. S., Davidson, N. E., Gralow, J., Harris, L. N., Kutteh, L. A., Hillman, D. W., Jenkins, R. B. & Chen, B., Jan 18 2012, In : Journal of the National Cancer Institute. 104, 2, p. 159-162 4 p.

Research output: Contribution to journalArticle

Medical Oncology
United States Food and Drug Administration
Disease-Free Survival
Fluorescence In Situ Hybridization
Immunohistochemistry
130 Citations (Scopus)

Probable rapid eye movement sleep behavior disorder increases risk for mild cognitive impairment and Parkinson disease: A population-based study

Boot, B. P., Boeve, B. F., Roberts, R. O., Ferman, T. J., Geda, Y. E., Pankratz, V. S., Ivnik, R. J., Smith, G. E., McDade, E., Christianson, T. J. H., Knopman, D. S., Tangalos, E. G., Silber, M. H. & Petersen, R. C., Jan 2012, In : Annals of Neurology. 71, 1, p. 49-56 8 p.

Research output: Contribution to journalArticle

REM Sleep Behavior Disorder
Parkinson Disease
Dementia
Population
Confidence Intervals
62 Citations (Scopus)

RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress

De, S., Kumari, J., Mudgal, R., Modi, P., Gupta, S., Futami, K., Goto, H., Lindor, N. M., Furuichi, Y., Mohanty, D. & Sengupta, S., 2012, In : Journal of Cell Science. 125, 10, p. 2509-2522 14 p.

Research output: Contribution to journalArticle

Rothmund-Thomson Syndrome
Mitochondria
Mitochondrial DNA
DNA Damage
Nuclear Localization Signals
112 Citations (Scopus)

Reevaluating the imaging definition of tumor progression: Perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival

Hu, L. S., Eschbacher, J. M., Heiserman, J. E., Dueck, A., Shapiro, W. R., Liu, S., Karis, J. P., Smith, K. A., Coons, S. W., Nakaji, P., Spetzler, R. F., Feuerstein, B. G., Debbins, J. & Baxter, L. C., Jul 2012, In : Neuro-Oncology. 14, 7, p. 919-930 12 p.

Research output: Contribution to journalArticle

Glioblastoma
Necrosis
Perfusion
Radiation
Survival
61 Citations (Scopus)

Relative intake of macronutrients impacts risk of mild cognitive impairment or dementia

Roberts, R. O., Roberts, L. A., Geda, Y. E., Cha, R. H., Pankratz, V. S., O'Connor, H. M., Knopman, D. S. & Petersen, R. C., 2012, In : Journal of Alzheimer's Disease. 32, 2, p. 329-339 11 p.

Research output: Contribution to journalArticle

Dementia
Energy Intake
Fats
Carbohydrates
Proteins

Response

Perez, E. A. & Dueck, A., Jun 20 2012, In : Journal of the National Cancer Institute. 104, 12, p. 958-959 2 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Return of individual research results from genome-wide association studies: Experience of the Electronic Medical Records and Genomics (eMERGE) Network

Fullerton, S. M., Wolf, W. A., Brothers, K. B., Clayton, E. W., Crawford, D. C., Denny, J. C., Greenland, P., Koenig, B. A., Leppig, K. A., Lindor, N. M., McCarty, C. A., McGuire, A. L., McPeek Hinz, E. R., Mirel, D. B., Ramos, E. M., Ritchie, M. D., Smith, M. E., Waudby, C. J., Burke, W. & Jarvik, G. P., Apr 2012, In : Genetics in Medicine. 14, 4, p. 424-431 8 p.

Research output: Contribution to journalArticle

Electronic Health Records
Genome-Wide Association Study
Genomics
Decision Making
Research
126 Citations (Scopus)

Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome

Win, A. K., Lindor, N. M., Young, J. P., MacRae, F. A., Young, G. P., Williamson, E., Parry, S., Goldblatt, J., Lipton, L., Winship, I., Leggett, B., Tucker, K. M., Giles, G. G., Buchanan, D. D., Clendenning, M., Rosty, C., Arnold, J., Joan Levine, A., Haile, R. W., Gallinger, S. & 4 others, Marchand, L. L., Newcomb, P. A., Hopper, J. L. & Jenkins, M. A., Sep 19 2012, In : Journal of the National Cancer Institute. 104, 18, p. 1363-1372 10 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Colorectal Neoplasms
Confidence Intervals
Neoplasms
Incidence
3 Citations (Scopus)

The changing landscape of axillary surgery: Which breast cancer patients may still benefit from complete axillary lymph node dissection?

McGhan, L. J., Dueck, A., Gray, R. J., Wasif, N., McCullough, A. E. & Pockaj, B. A., Sep 1 2012, In : Journal of Surgical Oncology. 106, 3, p. 254-259 6 p.

Research output: Contribution to journalArticle

Lymph Node Excision
Frozen Sections
Breast Neoplasms
Neoplasm Metastasis
Lymph Nodes
7 Citations (Scopus)

The germline MLH1 K618A variant and susceptibility to lynch syndrome-associated tumors

Medeiros, F., Lindor, N. M., Couch, F. J. & Highsmith, W. E. J., May 2012, In : Journal of Molecular Diagnostics. 14, 3, p. 264-273 10 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Gene Frequency
Neoplasms
Mutation
Neoplasm Genes
12 Citations (Scopus)

The impact of concomitant medication use on patient eligibility for phase i cancer clinical trials

Borad, M. J., Curtis, K. K., Babiker, H. M., Benjamin, M., Tibes, R., Ramanathan, R. K., Wright, K., Dueck, A., Jameson, G. & Von Hoff, D. D., 2012, In : Journal of Cancer. 3, 1, p. 345-353 9 p.

Research output: Contribution to journalArticle

Investigational Drugs
Clinical Trials
Confidence Intervals
Neoplasms
Cytochrome P-450 Enzyme System
46 Citations (Scopus)

The impact of obesity on breast cancer: A Retrospective review

Haakinson, D. J., Leeds, S. G., Dueck, A., Gray, R. J., Wasif, N., Stucky, C. C. H., Northfelt, D. W., Apsey, H. A. & Pockaj, B. A., Sep 2012, In : Annals of Surgical Oncology. 19, 9, p. 3012-3018 7 p.

Research output: Contribution to journalArticle

Obesity
Breast Neoplasms
Neoplasms
Incidence
Lymph Nodes
133 Citations (Scopus)

The incidence of MCI differs by subtype and is higher in men: The Mayo Clinic study of aging

Roberts, R. O., Geda, Y. E., Knopman, D. S., Cha, R. H., Pankratz, V. S., Boeve, B. F., Tangalos, E. G., Ivnik, R. J., Rocca, W. A. & Petersen, R. C., Jan 31 2012, In : Neurology. 78, 5, p. 342-351 10 p.

Research output: Contribution to journalArticle

Incidence
Education
Cognitive Dysfunction
Clinic
Mild Cognitive Impairment
9 Citations (Scopus)

Underuse of curative surgery for early stage upper gastrointestinal cancers in the United States

McGhan, L. J., Etzioni, D. A., Gray, R. J., Pockaj, B. A., Coan, K. E. & Wasif, N., Sep 2012, In : Journal of Surgical Research. 177, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

Gastrointestinal Neoplasms
Gallbladder Neoplasms
Neoplasms
Survival
Biliary Tract
2011
19 Citations (Scopus)

A novel mutation of LAMB2 in a multigenerational mennonite family reveals a new phenotypic variant of Pierson syndrome

Mohney, B. G., Pulido, J. S., Lindor, N. M., Hogan, M. C., Consugar, M. B., Peters, J., Pankratz, V. S., Nasr, S. H., Smith, S. J., Gloor, J., Kubly, V., Spencer, D., Nielson, R., Puffenberger, E. G., Strauss, K. A., Morton, D. H., Eldahdah, L. & Harris, P. C., Jun 2011, In : Ophthalmology. 118, 6, p. 1137-1144 8 p.

Research output: Contribution to journalArticle

Mutation
Laminin
Retinal Detachment
Kidney
Eye Manifestations
1 Citation (Scopus)

Antidepressant prescription pattern in a hospice program

Shiroma, P. R., Geda, Y. E., Mohan, A. & Richardson, J., May 2011, In : American Journal of Hospice and Palliative Medicine. 28, 3, p. 193-197 5 p.

Research output: Contribution to journalArticle

Hospice Care
Antidepressive Agents
Prescriptions
Hospices
Terminally Ill
9 Citations (Scopus)
Apolipoprotein E4
Homozygote
Cognition
Anxiety
Sex Education
9 Citations (Scopus)
Dandy-Walker Syndrome
Tongue
Mutation
Type 2 Oto-palato-digital syndrome
32 Citations (Scopus)

Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes

Win, A. K., Dowty, J. G., English, D. R., Campbell, P. T., Young, J. P., Winship, I., MacRae, F. A., Lipton, L., Parry, S., Young, G. P., Buchanan, D. D., Martínez, M. E., Jacobs, E. T., Ahnen, D. J., Haile, R. W., Casey, G., Baron, J. A., Lindor, N. M., Thibodeau, S. N., Newcomb, P. A. & 5 others, Potter, J. D., Le Marchand, L., Gallinger, S., Hopper, J. L. & Jenkins, M. A., Jun 28 2011, In : British Journal of Cancer. 105, 1, p. 162-169 8 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Germ-Line Mutation
Colorectal Neoplasms
Body Mass Index
Mutation
19 Citations (Scopus)

Body mass index in early adulthood and endometrial cancer risk for mismatch repair gene mutation carriers

Win, A. K., Dowty, J. G., Antill, Y. C., English, D. R., Baron, J. A., Young, J. P., Giles, G. G., Southey, M. C., Winship, I., Lipton, L., Parry, S., Thibodeau, S. N., Haile, R. W., Gallinger, S., Le Marchand, L., Lindor, N. M., Newcomb, P. A., Hopper, J. L. & Jenkins, M. A., Apr 2011, In : Obstetrics and Gynecology. 117, 4, p. 899-905 7 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Endometrial Neoplasms
Body Mass Index
Mutation
Genes
20 Citations (Scopus)

Breast medical oncologists' use of standard prognostic factors to predict a 21-gene recurrence score

Kamal, A. H., Loprinzi, C. L., Reynolds, C., Dueck, A., Geiger, X. J., Ingle, J. N., Carlson, R. W., Hobday, T. J., Winer, E. P. & Goetz, M. P., 2011, In : Oncologist. 16, 10, p. 1359-1366 8 p.

Research output: Contribution to journalArticle

Breast
Recurrence
Genes
Oncologists
Drug Therapy
44 Citations (Scopus)

Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer

Win, A. K., Cleary, S. P., Dowty, J. G., Baron, J. A., Young, J. P., Buchanan, D. D., Southey, M. C., Burnett, T., Parfrey, P. S., Green, R. C., Marchand, L. L., Newcomb, P. A., Haile, R. W., Lindor, N. M., Hopper, J. L., Gallinger, S. & Jenkins, M. A., Nov 1 2011, In : International Journal of Cancer. 129, 9, p. 2256-2262 7 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Liver Neoplasms
Mutation
Registries
Neoplasms
46 Citations (Scopus)

Cerebrovascular risk factors and preclinical memory decline in healthy APOE ε4 homozygotes

Caselli, R. J., Dueck, A., Locke, D. E., Sabbagh, M. N., Ahern, G. L., Rapcsak, S. Z., Baxter, L. C., Yaari, R., Woodruff, B. K., Hoffman-Snyder, C., Rademakers, R. V., Findley, S. & Reiman, E. M., Mar 22 2011, In : Neurology. 76, 12, p. 1078-1084 7 p.

Research output: Contribution to journalArticle

Long-Term Memory
Homozygote
Verbal Learning
Heterozygote
Tobacco Products
47 Citations (Scopus)

C-MYC alterations and association with patient outcome in early-stage HER2-positive breast cancer from the North Central Cancer Treatment Group N9831 adjuvant trastuzumab trial

Perez, E. A., Jenkins, R. B., Dueck, A., Wiktor, A. E., Bedroske, P. P., Anderson, S. K., Ketterling, R. P., Sukov, W. R., Kanehira, K., Chen, B., Geiger, X. J., Andorfer, C. A., McCullough, A. E., Davidson, N. E., Martino, S., Sledge, G. W., Kaufman, P. A., Kutteh, L. A., Gralow, J. R., Harris, L. N. & 3 others, Ingle, J. N., Lingle, W. L. & Reinholz, M. M., Feb 20 2011, In : Journal of Clinical Oncology. 29, 6, p. 651-659 9 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Chromosomes, Human, Pair 8
Neoplasms
Disease-Free Survival
Therapeutics
50 Citations (Scopus)

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

Mulligan, A. M., Couch, F. J., Barrowdale, D., Domchek, S. M., Eccles, D., Nevanlinna, H., Ramus, S. J., Robson, M., Sherman, M. E., Spurdle, A. B., Wappenschmidt, B., Lee, A., McGuffog, L., Healey, S., Sinilnikova, O. M., Janavicius, R., Hansen, T. V., Nielsen, F. C., Ejlertsen, B., Osorio, A. & 162 others, Muñoz-Repeto, I., Durán, M., Godino, J., Pertesi, M., Benítez, J., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Cattaneo, E., Bonanni, B., Viel, A., Pasini, B., Papi, L., Ottini, L., Savarese, A., Bernard, L., Radice, P., Hamann, U., Verheus, M., Meijers-Heijboer, H. E. J., Wijnen, J., Gómez García, E. B., Nelen, M. R., Kets, C. M., Seynaeve, C., Tilanus-Linthorst, M. M. A., van der Luijt, R. B., Os, T. V., Rookus, M., Frost, D., Jones, J. L., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Adlard, J., Davidson, R., Cook, J., Donaldson, A., Dorkins, H., Gregory, H., Eason, J., Houghton, C., Barwell, J., Side, L. E., McCann, E., Murray, A., Peock, S., Godwin, A. K., Schmutzler, R. K., Rhiem, K., Engel, C., Meindl, A., Ruehl, I., Arnold, N., Niederacher, D., Sutter, C., Deissler, H., Gadzicki, D., Kast, K., Preisler-Adams, S., Varon-Mateeva, R., Schoenbuchner, I., Fiebig, B., Heinritz, W., Schäfer, D., Gevensleben, H., Caux-Moncoutier, V., Fassy-Colcombet, M., Cornelis, F., Mazoyer, S., Léoné, M., Boutry-Kryza, N., Hardouin, A., Berthet, P., Muller, D., Fricker, J. P., Mortemousque, I., Pujol, P., Coupier, I., Lebrun, M., Kientz, C., Longy, M., Sevenet, N., Stoppa-Lyonnet, D., Isaacs, C., Caldes, T., de la Hoya, M., Heikkinen, T., Aittomäki, K., Blanco, I., Lazaro, C., Barkardottir, R. B., Soucy, P., Dumont, M., Simard, J., Montagna, M., Tognazzo, S., D'Andrea, E., Fox, S., Yan, M., Rebbeck, T., Olopade, O. I., Weitzel, J. N., Lynch, H. T., Ganz, P. A., Tomlinson, G. E., Wang, X., Fredericksen, Z., Pankratz, V. S., Lindor, N. M., Szabo, C., Offit, K., Sakr, R., Gaudet, M., Bhatia, J., Kauff, N., Singer, C. F., Tea, M. K., gschwantler-kaulich, D., Fink-Retter, A., Mai, P. L., Greene, M. H., Imyanitov, E., O'Malley, F. P., Ozcelik, H., Glendon, G., Toland, A. E., Gerdes, A. M., Thomassen, M., Kruse, T. A., Jensen, U. B., Skytte, A. B., Caligo, M. A., Soller, M., Henriksson, K., Wachenfeldt, V. A., Arver, B., Stenmark-Askmalm, M., Karlsson, P., Ding, Y. C., Neuhausen, S. L., Beattie, M., Pharoah, P. D. P., Moysich, K. B., Nathanson, K. L., Karlan, B. Y., Gross, J., John, E. M., Daly, M. B., Buys, S. M., Southey, M. C., Hopper, J. L., Terry, M. B., Chung, W., Miron, A. F., Goldgar, D., Chenevix-Trench, G., Easton, D. F., Andrulis, I. L. & Antoniou, A. C., Nov 2 2011, In : Breast Cancer Research. 13, 6, R110.

Research output: Contribution to journalArticle

Alleles
Estrogens
Research Personnel
Breast Neoplasms
Mutation
8 Citations (Scopus)

Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers

Spurdle, A. B., Marquart, L., McGuffog, L., Healey, S., Sinilnikova, O., Wan, F., Chen, X., Beesley, J., Singer, C. F., Dressler, A. C., Gschwantler-Kaulich, D., Blum, J. L., Tung, N., Weitzel, J., Lynch, H., Garber, J., Easton, D. F., Peock, S., Cook, M., Oliver, C. T. & 58 others, Frost, D., Conroy, D., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Davidson, R., Chu, C., Eccles, D., Selkirk, C. G., Daly, M., Isaacs, C., Stoppa-Lyonnet, D., Sinilnikova, O. M., Buecher, B., Belotti, M., Mazoyer, S., Barjhoux, L., Verny-Pierre, C., Lasset, C., Dreyfus, H., Pujol, P., Collonge-Rame, M. A., Rookus, M. A., Verhoef, S., Kriege, M., Hoogerbrugge, N., Ausems, M. G. E. M., Van Os, T. A., Wijnen, J., Devilee, P., Meijers-Heijboer, H. E. J., Blok, M. J., Heikkinen, T., Nevanlinna, H., Jakubowska, A., Lubiński, J., Huzarski, T., Byrski, T., Durocher, F., Couch, F. J., Lindor, N. M., Wang, X., Thomassen, M., Domchek, S., Nathanson, K., Caligo, M. A., Jernström, H., Liljegren, A., Ehrencrona, H., Karlsson, P., Ganz, P. A., Olopade, O. I., Tomlinson, G., Neuhausen, S., Antoniou, A. C., Chenevix-Trench, G. & Rebbeck, T. R., May 2011, In : Cancer Epidemiology Biomarkers and Prevention. 20, 5, p. 1032-1038 7 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Mutation
Haplotypes
Neoplasms
Single Nucleotide Polymorphism
2 Citations (Scopus)

Current Management of Anal Fissure

Etzioni, D. A., Mar 2011, In : Seminars in Colon and Rectal Surgery. 22, 1, p. 2-8 7 p.

Research output: Contribution to journalArticle

Fissure in Ano
Nitroglycerin
Calcium Channel Blockers
Constipation
Therapeutics
45 Citations (Scopus)

Cytokeratin-19 and Mammaglobin gene expression in circulating tumor cells from metastatic breast cancer patients enrolled in North Central Cancer Treatment Group trials, N0234/336/436/437

Reinholz, M. M., Kitzmann, K. A., Tenner, K., Hillman, D., Dueck, A., Hobday, T. J., Northfelt, D. W., Moreno Aspitia, A., Roy, V., LaPlant, B., Allred, J. B., Stella, P. J., Lingle, W. L. & Perez, E. A., Nov 15 2011, In : Clinical Cancer Research. 17, 22, p. 7183-7193 11 p.

Research output: Contribution to journalArticle

Keratin-19
Circulating Neoplastic Cells
Breast Neoplasms
Gene Expression
Messenger RNA
21 Citations (Scopus)

Determining the frequency of de novo germline mutations in DNA mismatch repair genes

Win, A. K. O., Jenkins, M. A., Buchanan, D. D., Clendenning, M., Young, J. P., Giles, G. G., Goldblatt, J., Leggett, B. A., Hopper, J. L., Thibodeau, S. N. & Lindor, N. M., Aug 2011, In : Journal of Medical Genetics. 48, 8, p. 530-534 5 p.

Research output: Contribution to journalArticle

DNA Mismatch Repair
Germ-Line Mutation
Mutation
Genes
Hereditary Nonpolyposis Colorectal Neoplasms
5 Citations (Scopus)

Does size matter? Technical considerations of a regenerative tissue matrix for use in reconstructive surgery

Craft, R. O., Rebecca, A. M., Flahive, C., Casey, W. J., Dueck, A. & Harold, K. L., Jun 2011, In : Canadian Journal of Plastic Surgery. 19, 2, p. 51-52 2 p.

Research output: Contribution to journalArticle

Reconstructive Surgical Procedures
Acellular Dermis
27 Citations (Scopus)

Effects of carpal tunnel syndrome on adaptation of multi-digit forces to object weight for whole-hand manipulation

Zhang, W., Johnston, J. A., Ross, M. A., Smith, A. A., Coakley, B. J., Gleason, E. A., Dueck, A. & Santello, M., Nov 16 2011, In : PLoS One. 6, 11, e27715.

Research output: Contribution to journalArticle

Carpal Tunnel Syndrome
Tunnels
hands
Hand
Weights and Measures

Engaging in cognitive activities, aging, and mild cognitive impairment: A population-based study

Geda, Y. E., Topazian, H. M., Lewis, R. A., Roberts, R. O., Knopman, D. S., Pankratz, V. S., Christianson, T. J. H. C., Boeve, B. F., Tangalos, E. G., Ivnik, R. J. & Petersen, R. C., 2011, In : Journal of Neuropsychiatry and Clinical Neurosciences. 23, 2, p. 149-154 6 p.

Research output: Contribution to journalArticle

Reading
Population
Newspapers
Music
Cross-Sectional Studies
39 Citations (Scopus)

Evaluating the serial use of the myelofibrosis symptom assessment form for measuring symptomatic improvement: Performance in 87 myelofibrosis patients on a JAK1 and JAK2 inhibitor (INCB018424) clinical trial

Mesa, R. A., Kantarjian, H., Tefferi, A., Dueck, A., Levy, R., Vaddi, K., Erickson-Viitanen, S., Thomas, D. A., Cortes, J., Borthakur, G., Pardanani, A. D., Estrov, Z. & Verstovsek, S., Nov 1 2011, In : Cancer. 117, 21, p. 4869-4877 9 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Symptom Assessment
Clinical Trials
Splenomegaly
INCB018424
1 Citation (Scopus)

Evaluation and Nonoperative Management of Colonic Diverticular Disease

Fraser, J. D. & Etzioni, D. A., Sep 2011, In : Seminars in Colon and Rectal Surgery. 22, 3, p. 154-156 3 p.

Research output: Contribution to journalArticle

Colonic Diseases
Diverticulitis
Inpatients
Therapeutics
Exercise
5 Citations (Scopus)

Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2

Osorio, A., Milne, R. L., Alonso, R., Pita, G., Peterlongo, P., Teulé, A., Nathanson, K. L., Domchek, S. M., Rebbeck, T., Lasa, A., Konstantopoulou, I., Hogervorst, F. B., Verhoef, S., Van Dooren, M. F., Jager, A., Ausems, M. G. E. M., Aalfs, C. M., Van Asperen, C. J., Vreeswijk, M., Waisfisz, Q. & 52 others, Van Roozendaal, C. E., Ligtenberg, M. J., Easton, D. F., Peock, S., Cook, M., Oliver, C. T., Frost, D., Curzon, B., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Davidson, R., Adlard, J., Eccles, D., Ong, K. R., Douglas, F., Downing, S., Brewer, C., Walker, L., Nevanlinna, H., Aittomäki, K., Couch, F. J., Fredericksen, Z., Lindor, N. M., Godwin, A., Isaacs, C., Caligo, M. A., Loman, N., Jernström, H., Barbany-Bustinza, G., Liljegren, A., Ehrencrona, H., Stenmark-Askmalm, M., Feliubadaló, L., Manoukian, S., Peissel, B., Zaffaroni, D., Bonanni, B., Fortuzzi, S., Johannsson, O. T., Chenevix-Trench, G., Chen, X. C., Beesley, J., Spurdle, A. B., Sinilnikova, O. M., Healey, S., McGuffog, L., Antoniou, A. C., Brunet, J., Radice, P. & Benítez, J., Apr 12 2011, In : British Journal of Cancer. 104, 8, p. 1356-1361 6 p.

Research output: Contribution to journalArticle

Research Personnel
Mutation
DNA Repair
Single Nucleotide Polymorphism
Genes
54 Citations (Scopus)

Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases

Rumilla, K., Schowalter, K. V., Lindor, N. M., Thomas, B. C., Mensink, K. A., Gallinger, S., Holter, S., Newcomb, P. A., Potter, J. D., Jenkins, M. A., Hopper, J. L., Long, T. I., Weisenberger, D. J., Haile, R. W., Casey, G., Laird, P. W., Le Marchand, L. & Thibodeau, S. N., Jan 2011, In : Journal of Molecular Diagnostics. 13, 1, p. 93-99 7 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Germ-Line Mutation
Mutation
Methylation
DNA Repair Enzymes
13 Citations (Scopus)

Germline PKHD1 mutations are protective against colorectal cancer

Ward, C. J., Wu, Y., Johnson, R. A., Woollard, J. R., Bergstralh, E. J., Cicek, M., Bakeberg, J., Rossetti, S., Heyer, C. M., Petersen, G. M., Lindor, N. M., Thibodeau, S. N., Harris, P. C., Torres, V., Hogan, M. C. & Boardman, L. A., Mar 2011, In : Human Genetics. 129, 3, p. 345-349 5 p.

Research output: Contribution to journalArticle

Germ-Line Mutation
Colorectal Neoplasms
Mutation
Autosomal Recessive Polycystic Kidney
Adenocarcinoma