Health Sciences Research

Research Output 1992 2020

5 Citations (Scopus)

Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2

Osorio, A., Milne, R. L., Alonso, R., Pita, G., Peterlongo, P., Teulé, A., Nathanson, K. L., Domchek, S. M., Rebbeck, T., Lasa, A., Konstantopoulou, I., Hogervorst, F. B., Verhoef, S., Van Dooren, M. F., Jager, A., Ausems, M. G. E. M., Aalfs, C. M., Van Asperen, C. J., Vreeswijk, M., Waisfisz, Q. & 52 others, Van Roozendaal, C. E., Ligtenberg, M. J., Easton, D. F., Peock, S., Cook, M., Oliver, C. T., Frost, D., Curzon, B., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Davidson, R., Adlard, J., Eccles, D., Ong, K. R., Douglas, F., Downing, S., Brewer, C., Walker, L., Nevanlinna, H., Aittomäki, K., Couch, F. J., Fredericksen, Z., Lindor, N. M., Godwin, A., Isaacs, C., Caligo, M. A., Loman, N., Jernström, H., Barbany-Bustinza, G., Liljegren, A., Ehrencrona, H., Stenmark-Askmalm, M., Feliubadaló, L., Manoukian, S., Peissel, B., Zaffaroni, D., Bonanni, B., Fortuzzi, S., Johannsson, O. T., Chenevix-Trench, G., Chen, X. C., Beesley, J., Spurdle, A. B., Sinilnikova, O. M., Healey, S., McGuffog, L., Antoniou, A. C., Brunet, J., Radice, P. & Benítez, J., Apr 12 2011, In : British Journal of Cancer. 104, 8, p. 1356-1361 6 p.

Research output: Contribution to journalArticle

Research Personnel
Mutation
DNA Repair
Single Nucleotide Polymorphism
Genes
8 Citations (Scopus)

Evidence-based assessments of clinical actionability in the context of secondary findings: Updates from ClinGen's Actionability Working Group

on behalf of the ClinGen Resource, Nov 1 2018, In : Human Mutation. 39, 11, p. 1677-1685 9 p.

Research output: Contribution to journalArticle

Genomics
Medical Genetics
Decision Support Techniques
Practice Guidelines
Genes
20 Citations (Scopus)

Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers

Walker, L. C., Fredericksen, Z. S., Wang, X., Tarrell, R., Pankratz, V. S., Lindor, N. M., Beesley, J., Healey, S., Chen, X., Stoppa-Lyonnet, D., Tirapo, C., Giraud, S., Mazoyer, S., Muller, D., Fricker, J. P., Delnatte, C. D., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Schönbuchner, I. & 53 others, Deissler, H., Meindl, A., Hogervorst, F. B., Verheus, M., Hooning, M. J., van den Ouweland, A. M. W., Nelen, M. R., Ausems, M. G. E. M., Aalfs, C. M., van Asperen, C. J., Devilee, P., Gerrits, M. M., Waisfisz, Q., Szabo, C. I., Easton, D. F., Peock, S., Cook, M., Oliver, C. T., Frost, D., Harrington, P., Evans, D. G., Lalloo, F., Eeles, R., Izatt, L., Chu, C., Davidson, R., Eccles, D., Ong, K. R., Cook, J., Rebbeck, T., Nathanson, K. L., Domchek, S. M., Singer, C. F., Gschwantler-Kaulich, D., Dressler, A. C., Pfeiler, G., Godwin, A. K., Heikkinen, T., Nevanlinna, H., Agnarsson, B. A., Caligo, M. A., Olsson, H., Kristoffersson, U., Liljegren, A., Arver, B., Karlsson, P., Melin, B., Sinilnikova, O. M., McGuffog, L., Antoniou, A. C., Chenevix-Trench, G., Spurdle, A. B. & Couch, F. J., Nov 29 2010, In : Breast Cancer Research. 12, 6, R102.

Research output: Contribution to journalArticle

Breast Neoplasms
Mutation
Single Nucleotide Polymorphism
Genes
Modifier Genes
21 Citations (Scopus)
Fatigue
Brain
Linear Models
Temporal Lobe
Atrophy
Dementia
Lewy Body Disease
Alzheimer Disease
Frontotemporal Dementia
29 Citations (Scopus)

Exploring how the tobacco industry presents and promotes itself in social media

Liang, Y., Zheng, X., Zeng, D. D., Zhou, X., Leischow, S. J. & Chung, W., Jan 1 2015, In : Journal of Medical Internet Research. 17, 1, p. e24

Research output: Contribution to journalArticle

Tobacco Industry
Social Media
Tobacco Products
Tobacco
History
1 Citation (Scopus)

Exploring the spatiotemporal genetic heterogeneity in metastatic lung adenocarcinoma using a nuclei flow-sorting approach

Lorber, T., Andor, N., Dietsche, T., Perrina, V., Juskevicius, D., Pereira, K., Greer, S. U., Krause, A., Müller, D. C., Savic Prince, S., Lardinois, D., Barrett, M., Ruiz, C. & Bubendorf, L., Jan 1 2019, (Accepted/In press) In : Journal of Pathology.

Research output: Contribution to journalArticle

Genetic Heterogeneity
Neoplasms
Mutation
Neoplasm Metastasis
Chromosomal Instability
1 Citation (Scopus)

Factors Associated with Emergency Department Utilization and Admission in Patients with Colorectal Cancer

Weidner, T. K., Kidwell, J. T., Etzioni, D. A., Sangaralingham, L. R., van Houten, H. K., Asante, D., Jeffery, M. M., Shah, N. D. & Wasif, N., Feb 12 2018, (Accepted/In press) In : Journal of Gastrointestinal Surgery. p. 1-8 8 p.

Research output: Contribution to journalArticle

Patient Admission
Hospital Emergency Service
Colorectal Neoplasms
Logistic Models
Comorbidity
13 Citations (Scopus)

Factors influencing time between biopsy and definitive surgery for malignant melanoma: do they impact clinical outcome?

Carpenter, S., Pockaj, B. A., Dueck, A., Gray, R., Kurtz, D., Sekulic, A. D. & Casey, W., Dec 2008, In : American Journal of Surgery. 196, 6, p. 834-843 10 p.

Research output: Contribution to journalArticle

Melanoma
Biopsy
Disease-Free Survival
Proportional Hazards Models
Survival
19 Citations (Scopus)

Failure of Colorectal Surgical Site Infection Predictive Models Applied to an Independent Dataset: Do They Add Value or Just Confusion?

Bergquist, J. R., Thiels, C. A., Etzioni, D. A., Habermann, E. B. & Cima, R. R., Dec 14 2015, (Accepted/In press) In : Journal of the American College of Surgeons.

Research output: Contribution to journalArticle

Surgical Wound Infection
Cross Infection
Datasets
Diagnosis-Related Groups
ROC Curve
11 Citations (Scopus)

Familial adenomatous polyposis and mental retardation caused by a de novo chromosomal deletion at 5q15-q22: Report of a case

Finch, R., Moore, H. G., Lindor, N. M., Jalal, S. M., Markowitz, A., Jhanwar, S., Offit, K. & Guillem, J. G., Nov 2005, In : Diseases of the Colon and Rectum. 48, 11, p. 2148-2152 5 p.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Intellectual Disability
APC Genes
Sigmoidoscopy
Tumor Suppressor Genes
56 Citations (Scopus)
Hereditary Nonpolyposis Colorectal Neoplasms
Colorectal Neoplasms
DNA Mismatch Repair
DNA Repair-Deficiency Disorders
Pedigree
179 Citations (Scopus)

Familial predisposition for colorectal cancer in chronic ulcerative colitis: A case-control study

Nuako, K. W., Ahlquist, D. A., Mahoney, D. W., Schaid, D. J., Siems, D. M. & Lindor, N. M., 1998, In : Gastroenterology. 115, 5, p. 1079-1083 5 p.

Research output: Contribution to journalArticle

Ulcerative Colitis
Case-Control Studies
Colorectal Neoplasms
Neoplasms
Colitis
26 Citations (Scopus)

Familial trigeminal neuralgia and contralateral hemifacial spasm

Duff, J. M., Spinner, R. J., Lindor, N. M., Dodick, D. W. & Atkinson, J. L. D., Jul 13 1999, In : Neurology. 53, 1, p. 216-218 3 p.

Research output: Contribution to journalArticle

Hemifacial Spasm
Trigeminal Neuralgia
Siblings
Mothers
23 Citations (Scopus)

Family history of colorectal cancer in BRAF p.V600emutated colorectal cancer cases

Buchanan, D. D., Win, A. K., Walsh, M. D., Walters, R. J., Clendenning, M., Nagler, B., Pearson, S. A., Macrae, F. A., Parry, S., Arnold, J., Winship, I., Giles, G. G., Lindor, N. M., Potter, J. D., Hopper, J. L., Rosty, C., Young, J. P. & Jenkins, M. A., May 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 5, p. 917-926 10 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Mutation
DNA Mismatch Repair
Confidence Intervals
Neoplasms
6 Citations (Scopus)

Family history of colorectal cancer is not associated with colorectal cancer survival regardless of microsatellite instability status

Phipps, A. I., Ahnen, D. J., Campbell, P. T., Win, A. K., Jenkins, M. A., Lindor, N. M., Gryfe, R., Potter, J. D. & Newcomb, P. A., 2014, In : Cancer Epidemiology Biomarkers and Prevention. 23, 8, p. 1700-1704 5 p.

Research output: Contribution to journalArticle

Microsatellite Instability
Colorectal Neoplasms
Confidence Intervals
Registries
Neoplasms
15 Citations (Scopus)

FDG-PET and Neuropsychiatric Symptoms among Cognitively Normal Elderly Persons: The Mayo Clinic Study of Aging

Krell-Roesch, J., Ruider, H., Lowe, V., Stokin, G. B., Pink, A., Roberts, R. O., Mielke, M. M., Knopman, D. S., Christianson, T. J., Machulda, M. M., Jack, C. R. J., Petersen, R. C. & Geda, Y. E., 2016, In : Journal of Alzheimer's Disease. 53, 4, p. 1609-1616 8 p.

Research output: Contribution to journalArticle

Asymptomatic Diseases
Equipment and Supplies
Alzheimer Disease
Odds Ratio
Depression
25 Citations (Scopus)

Feasibility Assessment of Patient Reporting of Symptomatic Adverse Events in Multicenter Cancer Clinical Trials

Basch, E., Dueck, A., Rogak, L. J., Minasian, L. M., Kelly, W. K., O'Mara, A. M., Denicoff, A. M., Seisler, D., Atherton, P. J., Paskett, E., Carey, L., Dickler, M., Heist, R. S., Himelstein, A., Rugo, H. S., Sikov, W. M., Socinski, M. A., Venook, A. P., Weckstein, D. J., Lake, D. E. & 5 others, Biggs, D. D., Freedman, R. A., Kuzma, C., Kirshner, J. J. & Schrag, D., Aug 1 2017, In : JAMA oncology. 3, 8, p. 1043-1050 8 p.

Research output: Contribution to journalArticle

Clinical Trials
Neoplasms
Research Personnel
Self Report
Multicenter Studies
9 Citations (Scopus)

Feasibility of electronic nicotine delivery systems in surgical patients

Nolan, M., Leischow, S., Croghan, I. T., Kadimpati, S., Hanson, A., Schroeder, D. & Warner, D. O., Aug 1 2016, In : Nicotine and Tobacco Research. 18, 8, p. 1757-1762 6 p.

Research output: Contribution to journalArticle

Nicotine
Tobacco Products
Smoking
Harm Reduction
Perioperative Period
9 Citations (Scopus)

Feasibility of implementing the patient-reported outcomes version of the common terminology criteria for adverse events in a multicenter trial: NCCTG N1048

Basch, E., Dueck, A., Rogak, L. J., Mitchell, S. A., Minasian, L. M., Denicoff, A. M., Wind, J. K., Shaw, M. C., Heon, N., Shi, Q. D., Ginos, B., Nelson, G. D., Meyers, J. P., Chang, G. J., Mamon, H. J., Weiser, M. R., Kolevska, T., Reeve, B. B., Bruner, D. W. & Schrag, D., Nov 1 2018, In : Journal of Clinical Oncology. 36, 31, p. 3120-3125 6 p.

Research output: Contribution to journalArticle

Terminology
Multicenter Studies
Compliance
National Cancer Institute (U.S.)
Self Report
27 Citations (Scopus)

Feasibility of Patient Reporting of Symptomatic Adverse Events via the Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) in a Chemoradiotherapy Cooperative Group Multicenter Clinical Trial

Basch, E., Pugh, S. L., Dueck, A., Mitchell, S. A., Berk, L., Fogh, S., Rogak, L. J., Gatewood, M., Reeve, B. B., Mendoza, T. R., O'Mara, A. M., Denicoff, A. M., Minasian, L. M., Bennett, A. V., Setser, A., Schrag, D., Roof, K., Moore, J. K., Gergel, T., Stephans, K. & 3 others, Rimner, A., DeNittis, A. & Bruner, D. W., Jun 1 2017, In : International Journal of Radiation Oncology Biology Physics. 98, 2, p. 409-418 10 p.

Research output: Contribution to journalArticle

terminology
Chemoradiotherapy
Terminology
Multicenter Studies
Clinical Trials
7 Citations (Scopus)

Feasibility study of online yoga for symptom management in patients with myeloproliferative neoplasms

Huberty, J., Eckert, R., Gowin, K., Mitchell, J., Dueck, A., Ginos, B. F., Larkey, L. & Mesa, R., Sep 30 2017, In : Haematologica. 102, 10, p. e384-e388

Research output: Contribution to journalLetter

Yoga
Feasibility Studies
Neoplasms
28 Citations (Scopus)

Female hormonal factors and the risk of endometrial cancer in Lynch syndrome

Dashti, S. G., Chau, R., Ouakrim, D. A., Buchanan, D. D., Clendenning, M., Young, J. P., Winship, I. M., Arnold, J., Ahnen, D. J., Haile, R. W., Casey, G., Gallinger, S., Thibodeau, S. N., Lindor, N. M., Le Marchand, L., Newcomb, P. A., Potter, J. D., Baron, J. A., Hopper, J. L., Jenkins, M. A. & 1 others, Win, A. K., Jul 7 2015, In : JAMA - Journal of the American Medical Association. 314, 1, p. 61-71 11 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Endometrial Neoplasms
DNA Mismatch Repair
Live Birth
Mutation
12 Citations (Scopus)

Fibrillar amyloid correlates of preclinical cognitive decline

Stonnington, C. M., Chen, K., Lee, W., Locke, D. E., Dueck, A., Liu, X., Roontiva, A., Fleisher, A. S., Caselli, R. J. & Reiman, E. M., Jan 2014, In : Alzheimer's and Dementia. 10, 1

Research output: Contribution to journalArticle

Apolipoprotein E4
Amyloid
Sex Education
Executive Function
Positron-Emission Tomography
5 Citations (Scopus)

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Vigorito, E., Kuchenbaecker, K. B., Beesley, J., Adlard, J., Agnarsson, B. A., Andrulis, I. L., Arun, B. K., Barjhoux, L., Belotti, M., Benitez, J., Berger, A., Bojesen, A., Bonanni, B., Brewer, C., Caldes, T., Caligo, M. A., Campbell, I., Chan, S. B., Claes, K. B. M., Cohn, D. E. & 126 others, Cook, J., Daly, M. B., Damiola, F., Davidson, R., Pauw, A. D., Delnatte, C., Diez, O., Domchek, S. M., Dumont, M., Durda, K., Dworniczak, B., Easton, D. F., Eccles, D., Edwinsdotter Ardnor, C., Eeles, R., Ejlertsen, B., Ellis, S., Evans, D. G., Feliubadalo, L., Fostira, F., Foulkes, W. D., Friedman, E., Frost, D., Gaddam, P., Ganz, P. A., Garber, J., Garcia-Barberan, V., Gauthier-Villars, M., Gehrig, A., Gerdes, A. M., Giraud, S., Godwin, A. K., Goldgar, D. E., Hake, C. R., Hansen, T. V. O., Healey, S., Hodgson, S., Hogervorst, F. B. L., Houdayer, C., Hulick, P. J., Imyanitov, E. N., Isaacs, C., Izatt, L., Izquierdo, A., Jacobs, L., Jakubowska, A., Janavicius, R., Jaworska-Bieniek, K., Jensen, U. B., John, E. M., Vijai, J., Karlan, B. Y., Kast, K., Investigators, KC. F., Khan, S., Kwong, A., Laitman, Y., Lester, J., Lesueur, F., Liljegren, A., Lubinski, J., Mai, P. L., Manoukian, S., Mazoyer, S., Meindl, A., Mensenkamp, A. R., Montagna, M., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Niederacher, D., Olah, E., Olopade, O. I., Ong, K. R., Osorio, A., Park, S. K., Paulsson-Karlsson, Y., Pedersen, I. S., Peissel, B., Peterlongo, P., Pfeiler, G., Phelan, C. M., Piedmonte, M., Poppe, B., Pujana, M. A., Radice, P., Rennert, G., Rodriguez, G. C., Rookus, M. A., Ross, E. A., Schmutzler, R. K., Simard, J., Singer, C. F., Slavin, T. P., Soucy, P., Southey, M., Steinemann, D., Stoppa-Lyonnet, D., Sukiennicki, G., Sutter, C., Szabo, C. I., Tea, M. K., Teixeira, M. R., Teo, S. H., Terry, M. B., Thomassen, M., Tibiletti, M. G., Tihomirova, L., Tognazzo, S., van Rensburg, E. J., Varesco, L., Varon-Mateeva, R., Vratimos, A., Weitzel, J. N., McGuffog, L., Kirk, J., Toland, A. E., Hamann, U., Lindor, N. M., Ramus, S. J., Greene, M. H., Couch, F. J., Offit, K., Pharoah, P. D. P., Chenevix-Trench, G. & Antoniou, A. C., Jan 1 2016, In : PLoS One. 11, 7, p. e0158801

Research output: Contribution to journalArticle

ovarian neoplasms
Ovarian Neoplasms
mutation
Mutation
Single Nucleotide Polymorphism
21 Citations (Scopus)

Form of 15q proximal duplication appears to be a normal euchromatic variant [3]

Jalal, S. M., Persons, D. L., Dewald, G. W. & Lindor, N. M., 1994, In : American Journal of Medical Genetics. 52, 4, p. 495-497 3 p.

Research output: Contribution to journalArticle

Chromosome Disorders
Angelman Syndrome
Prader-Willi Syndrome
Chromosomes, Human, Pair 15
Family Health
13 Citations (Scopus)

Fracture risk perception study: Patient self-perceptions of bone health often disagree with calculated fracture risk

Grover, M. L., Edwards, F. D., Chang, Y. H. H., Cook, C. B., Behrens, M. C. & Dueck, A., Jan 2014, In : Women's Health Issues. 24, 1

Research output: Contribution to journalArticle

Self Concept
self-image
Bone and Bones
Health
health
37 Citations (Scopus)

Fragile X syndrome due to a missense mutation

Myrick, L. K., Nakamoto-Kinoshita, M., Lindor, N. M., Kirmani, S., Cheng, X. & Warren, S. T., Oct 11 2014, In : European Journal of Human Genetics. 22, 10, p. 1185-1189 5 p.

Research output: Contribution to journalArticle

Fragile X Syndrome
Missense Mutation
Glycine
Glutamic Acid
Mutation
18 Citations (Scopus)

Frailty and Mortality Outcomes in Cognitively Normal Older People: Sex Differences in a Population-Based Study

Bartley, M. M., Geda, Y. E., Christianson, T. J. H., Shane Pankratz, V., Roberts, R. O. & Petersen, R. C., Jan 1 2016, In : Journal of the American Geriatrics Society. 64, 1, p. 132-137 6 p.

Research output: Contribution to journalArticle

Sex Characteristics
Mortality
Confidence Intervals
Population
Proportional Hazards Models
54 Citations (Scopus)

Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases

Rumilla, K., Schowalter, K. V., Lindor, N. M., Thomas, B. C., Mensink, K. A., Gallinger, S., Holter, S., Newcomb, P. A., Potter, J. D., Jenkins, M. A., Hopper, J. L., Long, T. I., Weisenberger, D. J., Haile, R. W., Casey, G., Laird, P. W., Le Marchand, L. & Thibodeau, S. N., Jan 2011, In : Journal of Molecular Diagnostics. 13, 1, p. 93-99 7 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Germ-Line Mutation
Mutation
Methylation
DNA Repair Enzymes
74 Citations (Scopus)

Frequency of loss of hMLH1 expression in colorectal carcinoma increases with advancing age

Kakar, S., Burgart, L. J., Thibodeau, S. N., Rabe, K. G., Petersen, G. M., Goldberg, R. M. & Lindor, N. M., Mar 15 2003, In : Cancer. 97, 6, p. 1421-1427 7 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Neoplasms
Descending Colon
Ascending Colon
Transverse Colon
4 Citations (Scopus)

From the laboratory to the clinic: sharing BRCA VUS reclassification tools with practicing genetics professionals

Augusto, B. M., Lake, P., Scherr, C. L., Couch, F. J., Lindor, N. M. & Vadaparampil, S. T., Nov 9 2017, (Accepted/In press) In : Journal of Community Genetics. p. 1-7 7 p.

Research output: Contribution to journalArticle

Patient Education
Research
Counselors
Postcards
83 Citations (Scopus)

Frontotemporal dementia and parkinsonism associated with the IVS1+1G→A mutation in progranulin: A clinicopathologic study

Boeve, B. F., Baker, M., Dickson, D. W., Parisi, J. E., Giannini, C., Josephs, K. A., Hutton, M., Pickering-Brown, S. M., Rademakers, R. V., Tang-Wai, D., Jack, C. R. J., Kantarci, K. M., Shiung, M. M., Golde, T., Smith, G. E., Geda, Y. E., Knopman, D. S. & Petersen, R. C., Nov 2006, In : Brain. 129, 11, p. 3103-3114 12 p.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Frontotemporal Lobar Degeneration
Presenilin-1
RNA Splice Sites
Mutation

Functional Activity and Neuropsychiatric Symptoms in Normal Aging and Mild Cognitive Impairment: The Mayo Clinic Study of Aging

Krell-Roesch, J., Cerhan, L. P., Machulda, M. M., Roberts, R. O., Mielke, M. M., Knopman, D. S., Syrjanen, J. A., Christianson, T. J., Petersen, R. C. & Geda, Y. E., Jan 1 2018, (Accepted/In press) In : Alzheimer Disease and Associated Disorders.

Research output: Contribution to journalArticle

Case-Control Studies
Cognitive Dysfunction
73 Citations (Scopus)

Functional movement disorders: Successful treatment with a physical therapy rehabilitation protocol

Czarnecki, K., Thompson, J. M., Seime, R., Geda, Y. E., Duffy, J. R. & Ahlskog, J. E., Mar 2012, In : Parkinsonism and Related Disorders. 18, 3, p. 247-251 5 p.

Research output: Contribution to journalArticle

Movement Disorders
Rehabilitation
Physical and Rehabilitation Medicine
Therapeutics
Physicians
15 Citations (Scopus)
Williams Syndrome
Nucleic Acid Hybridization
Craniosynostoses
Microcephaly
Chromosomes, Human, Pair 7
6 Citations (Scopus)
Epidemiology
Hemorrhage
Vulnerable Populations
Anticoagulants
Patient Participation
7 Citations (Scopus)

Gastrointestinal bleeding secondary to the new anticoagulants

Abraham, N. S. & Horsley-Silva, J. L., Sep 14 2016, (Accepted/In press) In : Current Opinion in Gastroenterology.

Research output: Contribution to journalArticle

Anticoagulants
Hemorrhage
Risk Management
Knowledge Management
Warfarin
59 Citations (Scopus)

Gastrointestinal Safety of Direct Oral Anticoagulants: A Large Population-Based Study

Abraham, N. S., Noseworthy, P., Yao, X., Sangaralingham, L. R. & Shah, N. D., Apr 1 2017, In : Gastroenterology. 152, 5, p. 1014-1022.e1

Research output: Contribution to journalArticle

Anticoagulants
Hemorrhage
Safety
Population
Confidence Intervals
12 Citations (Scopus)

Genetic counselors' practices and confidence regarding variant of uncertain significance results and reclassification from BRCA testing

Scherr, C. L., Lindor, N. M., Malo, T. L., Couch, F. J. & Vadaparampil, S. T., Dec 1 2015, In : Clinical Genetics. 88, 6, p. 523-529 7 p.

Research output: Contribution to journalArticle

Counselors
Demography
Guidelines
DNA
Surveys and Questionnaires

Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies

Pande, M., Joon, A., Brewster, A. M., Chen, W. V., Hopper, J. L., Eng, C., Shete, S., Casey, G., Schumacher, F., Lin, Y., Harrison, T. A., White, E., Ahsan, H., Andrulis, I. L., Whittemore, A. S., John, E. M., Win, A. K., Makalic, E., Schmidt, D. F., Kapuscinski, M. K. & 8 others, Ochs-Balcom, H. M., Gallinger, S., Jenkins, M. A., Newcomb, P. A., Lindor, N. M., Peters, U., Amos, C. I. & Lynch, P. M., Apr 1 2018, In : PLoS One. 13, 4, e0196245.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Genetic Predisposition to Disease
colorectal neoplasms
Genetic Markers
breast neoplasms
176 Citations (Scopus)

Genetic testing in an ethnically diverse cohort of high-risk women: A comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry

Nanda, R., Schumm, L. P., Cummings, S., Fackenthal, J. D., Sveen, L., Ademuyiwa, F., Cobleigh, M., Esserman, L., Lindor, N. M., Neuhausen, S. L. & Olopade, O. I., Oct 19 2005, In : Journal of the American Medical Association. 294, 15, p. 1925-1933 9 p.

Research output: Contribution to journalArticle

Genetic Testing
Mutation
African Americans
Breast Neoplasms
Ovarian Neoplasms
84 Citations (Scopus)

Genetic testing in the diagnosis and management of multiple endocrine neoplasia type II

Ledger, G. A., Khosla, S., Lindor, N. M., Thibodeau, S. N. & Gharib, H., 1995, In : Annals of Internal Medicine. 122, 2, p. 118-124 7 p.

Research output: Contribution to journalArticle

Multiple Endocrine Neoplasia
Genetic Testing
Pentagastrin
Information Storage and Retrieval
Calcitonin
2 Citations (Scopus)

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

Bien, S. A., Su, Y. R., Conti, D. V., Harrison, T. A., Qu, C., Guo, X., Lu, Y., Albanes, D., Auer, P. L., Banbury, B. L., Berndt, S. I., Bézieau, S., Brenner, H., Buchanan, D. D., Caan, B. J., Campbell, P. T., Carlson, C. S., Chan, A. T., Chang-Claude, J., Chen, S. & 58 others, Connolly, C. M., Easton, D. F., Feskens, E. J. M., Gallinger, S., Giles, G. G., Gunter, M. J., Hampe, J., Huyghe, J. R., Hoffmeister, M., Hudson, T. J., Jacobs, E. J., Jenkins, M. A., Kampman, E., Kang, H. M., Kühn, T., Küry, S., Lejbkowicz, F., Le Marchand, L., Milne, R. L., Li, L., Li, C. I., Lindblom, A., Lindor, N. M., Martín, V., McNeil, C. E., Melas, M., Moreno, V., Newcomb, P. A., Offit, K., Pharaoh, P. D. P., Potter, J. D., Qu, C., Riboli, E., Rennert, G., Sala, N., Schafmayer, C., Scacheri, P. C., Schmit, S. L., Severi, G., Slattery, M. L., Smith, J. D., Trichopoulou, A., Tumino, R., Ulrich, C. M., van Duijnhoven, F. J. B., Van Guelpen, B., Weinstein, S. J., White, E., Wolk, A., Woods, M. O., Wu, A. H., Abecasis, G. R., Casey, G., Nickerson, D. A., Gruber, S. B., Hsu, L., Zheng, W. & Peters, U., Apr 1 2019, In : Human genetics. 138, 4, p. 307-326 20 p.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Gene Expression
Genome-Wide Association Study
Transcriptome
Colon
9 Citations (Scopus)

Genetic variants in the cell cycle control pathways contribute to early onset colorectal cancer in Lynch syndrome

Chen, J., Etzel, C. J., Amos, C. I., Zhang, Q., Viscofsky, N., Lindor, N. M., Lynch, P. M. & Frazier, M. L., Nov 2009, In : Cancer Causes and Control. 20, 9, p. 1769-1777 9 p.

Research output: Contribution to journalArticle

Hereditary Nonpolyposis Colorectal Neoplasms
Cell Cycle Checkpoints
Age of Onset
Aurora Kinase A
Colorectal Neoplasms
7 Citations (Scopus)

Genetic variation in prostaglandin synthesis and related pathways, NSAID use and colorectal cancer risk in the colon Cancer Family Registry

Resler, A. J., Makar, K. W., Heath, L., Whitton, J., Potter, J. D., Poole, E. M., Habermann, N., Scherer, D., Duggan, D., Wang, H., Lindor, N. M., Passarelli, M. N., Baron, J. A., Newcomb, P. A., Le Marchand, L. & Ulrich, C. M., 2014, In : Carcinogenesis. 35, 9, p. 2121-2126 6 p., bgu119.

Research output: Contribution to journalArticle

Colonic Neoplasms
Prostaglandins
Registries
Colorectal Neoplasms
Anti-Inflammatory Agents
13 Citations (Scopus)

Genetic variation in the inflammation and innate immunity pathways and colorectal cancer risk

Wang, H., Taverna, D., Stram, D. O., Fortini, B. K., Cheng, I., Wilkens, L. R., Burnett, T., Makar, K. W., Lindor, N. M., Hopper, J. L., Gallinger, S., Baron, J. A., Haile, R., Kolonel, L. N., Henderson, B. E., Newcomb, P. A., Casey, G., Duggan, D., Ulrich, C. M. & Le Marchand, L., Nov 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 11, p. 2094-2101 8 p.

Research output: Contribution to journalArticle

Innate Immunity
Single Nucleotide Polymorphism
Colorectal Neoplasms
Inflammation
Oceanic Ancestry Group
14 Citations (Scopus)

Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry

Jiang, X., Castelao, J. E., Vandenberg, D., Carracedo, A., Redondo, C. M., Conti, D. V., Paredes Cotoré, J. P., Potter, J. D., Newcomb, P. A., Passarelli, M. N., Jenkins, M. A., Hopper, J. L., Gallinger, S., Le Marchand, L., Martínez, M. E., Ahnen, D. J., Baron, J. A., Lindor, N. M., Haile, R. W. & Gago-Dominguez, M., Apr 3 2013, In : PLoS One. 8, 4, e60464.

Research output: Contribution to journalArticle

colorectal neoplasms
Colonic Neoplasms
Registries
Colorectal Neoplasms
Single Nucleotide Polymorphism
169 Citations (Scopus)

Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

Couch, F. J., Wang, X., McGuffog, L., Lee, A., Olswold, C., Kuchenbaecker, K. B., Soucy, P., Fredericksen, Z., Barrowdale, D., Dennis, J., Gaudet, M. M., Dicks, E., Kosel, M., Healey, S., Sinilnikova, O. M., Lee, A., Bacot, F., Vincent, D., Hogervorst, F. B. L., Peock, S. & 473 others, Stoppa-Lyonnet, D., Jakubowska, A., Radice, P., Schmutzler, R. K., Domchek, S. M., Piedmonte, M., Singer, C. F., Friedman, E., Thomassen, M., Hansen, T. V. O., Neuhausen, S. L., Szabo, C. I., Blanco, I., Greene, M. H., Karlan, B. Y., Garber, J., Phelan, C. M., Weitzel, J. N., Montagna, M., Olah, E., Andrulis, I. L., Godwin, A. K., Yannoukakos, D., Goldgar, D. E., Caldes, T., Nevanlinna, H., Osorio, A., Terry, M. B., Daly, M. B., van Rensburg, E. J., Hamann, U., Ramus, S. J., Ewart Toland, A., Caligo, M. A., Olopade, O. I., Tung, N., Claes, K., Beattie, M. S., Southey, M. C., Imyanitov, E. N., Tischkowitz, M., Janavicius, R., John, E. M., Kwong, A., Diez, O., Balmaña, J., Barkardottir, R. B., Arun, B. K., Rennert, G., Teo, S. H., Ganz, P. A., Campbell, I., van der Hout, A. H., van Deurzen, C. H. M., Seynaeve, C., Gómez Garcia, E. B., van Leeuwen, F. E., Meijers-Heijboer, H. E. J., Gille, J. J. P., Ausems, M. G. E. M., Blok, M. J., Ligtenberg, M. J. L., Rookus, M. A., Devilee, P., Verhoef, S., van Os, T. A. M., Wijnen, J. T., Frost, D., Ellis, S., Fineberg, E., Platte, R., Evans, D. G., Izatt, L., Eeles, R. A., Adlard, J., Eccles, D. M., Cook, J., Brewer, C., Douglas, F., Hodgson, S., Morrison, P. J., Side, L. E., Donaldson, A., Houghton, C., Rogers, M. T., Dorkins, H., Eason, J., Gregory, H., McCann, E., Murray, A., Calender, A., Hardouin, A., Berthet, P., Delnatte, C., Nogues, C., Lasset, C., Houdayer, C., Leroux, D., Rouleau, E., Prieur, F., Damiola, F., Sobol, H., Coupier, I., Venat-Bouvet, L., Castera, L., Gauthier-Villars, M., Léoné, M., Pujol, P., Mazoyer, S., Bignon, Y. J., Złowocka-Perłowska, E., Gronwald, J., Lubinski, J., Durda, K., Jaworska, K., Huzarski, T., Spurdle, A. B., Viel, A., Peissel, B., Bonanni, B., Melloni, G., Ottini, L., Papi, L., Varesco, L., Tibiletti, M. G., Peterlongo, P., Volorio, S., Manoukian, S., Pensotti, V., Arnold, N., Engel, C., Deissler, H., Gadzicki, D., Gehrig, A., Kast, K., Rhiem, K., Meindl, A., Niederacher, D., Ditsch, N., Plendl, H., Preisler-Adams, S., Engert, S., Sutter, C., Varon-Mateeva, R., Wappenschmidt, B., Weber, B. H. F., Arver, B., Stenmark-Askmalm, M., Loman, N., Rosenquist, R., Einbeigi, Z., Nathanson, K. L., Rebbeck, T. R., Blank, S. V., Cohn, D. E., Rodriguez, G. C., Small, L., Friedlander, M., Bae-Jump, V. L., Fink-Retter, A., Rappaport, C., Gschwantler-Kaulich, D., Pfeiler, G., Lindor, N. M., Lindor, N. M., Kaufman, B., Shimon Paluch, S., Laitman, Y., Skytte, A. B., Gerdes, A. M., Pedersen, I. S., Moeller, S. T., Kruse, T. A., Jensen, U. B., Vijai, J., Sarrel, K., Robson, M., Kauff, N., Mulligan, A. M., Glendon, G., Ozcelik, H., Ejlertsen, B., Nielsen, F. C., Jønson, L., Andersen, M. K., Ding, Y. C., Steele, L., Foretova, L., Teulé, A., Lazaro, C., Brunet, J., Pujana, M. A., Mai, P. L., Loud, J. T., Walsh, C., Lester, J., Orsulic, S., Narod, S. A., Herzog, J., Sand, S. R., Tognazzo, S., Agata, S., Vaszko, T., Weaver, J., Stavropoulou, A. V., Buys, S. S., Romero, A., de la Hoya, M., Aittomäki, K., Muranen, T. A., Duran, M., Chung, W. K., Lasa, A., Dorfling, C. M., Miron, A., Benitez, J., Senter, L., Huo, D., Chan, S. B., Sokolenko, A. P., Chiquette, J., Tihomirova, L., Friebel, T. M., Agnarsson, B. A., Lu, K. H., Lejbkowicz, F., James, P. A., Hall, P., Dunning, A. M., Cunningham, J. M., Slager, S. L., Wang, C., Hart, S., Hart, S., Stevens, K., Simard, J., Pastinen, T., Pankratz, V. S., Offit, K., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C., Thorne, H., Niedermayr, E., Borg, Å., Olsson, H., Jernström, H., Henriksson, K., Harbst, K., Soller, M., Loman, N., Kristoffersson, U., Öfverholm, A., Nordling, M., Karlsson, P., Einbeigi, Z., von Wachenfeldt, A., Liljegren, A., Lindblom, A., Arver, B., Bustinza, G. B., Rantala, J., Melin, B., Ardnor, C. E., Emanuelsson, M., Ehrencrona, H., Pigg, M. H., Rosenquist, R., Stenmark-Askmalm, M., Liedgren, S., Rookus, M. A., Hogervorst, F. B. L., Verhoef, S., van Leeuwen, F. E., Schmidt, M. K., de Lange, J., Collée, J. M., van den Ouweland, A. M. W., Hooning, M. J., Seynaeve, C., van Asperen, C. J., Wijnen, J. T., Tollenaar, R. A., Devilee, P., van Cronenburg, T. C. T. E. F., Kets, C. M., Mensenkamp, A. R., Ausems, M. G. E. M., van der Luijt, R. B., Aalfs, C. M., van Os, T. A. M., Gille, J. J. P., Waisfisz, Q., Meijers-Heijboer, H. E. J., Gómez-Garcia, E. B., Blok, M. J., Oosterwijk, J. C., van der Hout, H., Mourits, M. J., de Bock, G. H., Peock, S., Frost, D., Ellis, S., Fineberg, E., Platte, R., Miedzybrodzka, Z., Gregory, H., Morrison, P., Jeffers, L., Cole, T., Ong, K. R., Hoffman, J., Donaldson, A., James, M., Tischkowitz, M., Paterson, J., Taylor, A., Murray, A., Rogers, M. T., McCann, E., Kennedy, M. J., Barton, D., Porteous, M., Drummond, S., Brewer, C., Kivuva, E., Searle, A., Goodman, S., Hill, K., Davidson, R., Murday, V., Bradshaw, N., Snadden, L., Longmuir, M., Watt, C., Gibson, S., Haque, E., Tobias, E., Duncan, A., Izatt, L., Jacobs, C., Langman, C., Dorkins, H., Brady, A., Melville, A., Randhawa, K., Barwell, J., Adlard, J., Serra-Feliu, G., Ellis, I., Houghton, C., Evans, D. G., Lalloo, F., Taylor, J., Side, L., Male, A., Berlin, C., Eason, J., Collier, R., Douglas, F., Claber, O., Jobson, I., Walker, L., McLeod, D., Halliday, D., Durell, S., Stayner, B., Eeles, R. A., Shanley, S., Rahman, N., Houlston, R., Stormorken, A., Bancroft, E., Page, E., Ardern-Jones, A., Kohut, K., Wiggins, J., Castro, E., Killick, E., Martin, S., Rea, G., Kulkarni, A., Cook, J., Quarrell, O., Bardsley, C., Hodgson, S., Goff, S., Brice, G., Winchester, L., Eddy, C., Tripathi, V., Attard, V., Lehmann, A., Eccles, D., Lucassen, A., Crawford, G., McBride, D., Smalley, S., Sinilnikova, O., Mazoyer, S., Damiola, F., Barjhoux, L., Verny-Pierre, C., Giraud, S., Léone, M., Stoppa-Lyonnet, D., Gauthier-Villars, M., Buecher, B., Houdayer, C., Moncoutier, V., Belotti, M., Tirapo, C., de Pauw, A., Bressac-de-Paillerets, B., Caron, O., Bignon, Y. J., Uhrhammer, N., Lasset, C., Bonadona, V., Handallou, S., Hardouin, A., Berthet, P., Sobol, H., Bourdon, V., Noguchi, T., Remenieras, A., Eisinger, F., Coupier, I., Pujol, P., Peyrat, J. P., Fournier, J., Révillion, F., Vennin, P., Adenis, C., Rouleau, E., Lidereau, R., Demange, L., Nogues, C., Muller, D., Fricker, J. P., Barouk-Simonet, E., Bonnet, F., Bubien, V., Sevenet, N., Longy, M., Toulas, C., Guimbaud, R., Gladieff, L., Feillel, V., Leroux, D., Dreyfus, H., Rebischung, C., Peysselon, M., Coron, F., Faivre, L., Prieur, F., Lebrun, M., Kientz, C., Ferrer, S. F., Frénay, M., Vénat-Bouvet, L., Delnatte, C., Mortemousque, I., Coulet, F., Colas, C., Soubrier, F., Sokolowska, J., Bronner, M., Lynch, H. T., Snyder, C. L., Angelakos, M., Maskiell, J. & Dite, G., 2013, In : PLoS Genetics. 9, 3, e1003212.

Research output: Contribution to journalArticle

ovarian neoplasms
Genome-Wide Association Study
breast neoplasms
Ovarian Neoplasms
mutation
68 Citations (Scopus)

Genome-wide association study of colorectal cancer identifies six new susceptibility loci

Schumacher, F. R., Schmit, S. L., Jiao, S., Edlund, C. K., Wang, H., Zhang, B., Hsu, L., Huang, S. C., Fischer, C. P., Harju, J. F., Idos, G. E., Lejbkowicz, F., Manion, F. J., McDonnell, K., McNeil, C. E., Melas, M., Rennert, H. S., Shi, W., Thomas, D. C., Van Den Berg, D. J. & 81 others, Hutter, C. M., Aragaki, A. K., Butterbach, K., Caan, B. J., Carlson, C. S., Chanock, S. J., Curtis, K. R., Fuchs, C. S., Gala, M., Giocannucci, E. L., Gogarten, S. M., Hayes, R. B., Henderson, B., Hunter, D. J., Jackson, R. D., Kolonel, L. N., Kooperberg, C., Kury, S., Lacroix, A., Laurie, C. C., Laurie, C. A., Lemire, M., Levine, D., Ma, J., Makar, K. W., Qu, C., Taverna, D., Ulrich, C. M., Wu, K., Kono, S., West, D. W., Berndt, S. I., Bezieau, S., Brenner, H., Campbell, P. T., Chan, A. T., Chang-Claude, J., Coetzee, G. A., Conti, D. V., Duggan, D., Figueiredo, J. C., Fortini, B. K., Gallinger, S. J., Gauderman, W. J., Giles, G., Green, R., Haile, R., Harrison, T. A., Hoffmeister, M., Hopper, J. L., Hudson, T. J., Jacobs, E., Iwasaki, M., Jee, S. H., Jenkins, M., Jia, W. H., Joshi, A., Li, L., Lindor, N. M., Matsuo, K., Moreno, V., Mukherjee, B., Newcomb, P. A., Potter, J. D., Raskin, L., Rennert, G., Rosse, S., Severi, G., Schoen, R. E., Seminara, D., Shu, X. O., Slattery, M. L., Tsugane, S., White, E., Xiang, Y. B., Zanke, B. W., Zheng, W., Le Marchand, L., Casey, G., Gruber, S. B. & Peters, U., Jul 7 2015, In : Nature Communications. 6, 7138.

Research output: Contribution to journalArticle

genome
Genome-Wide Association Study
loci
Colorectal Neoplasms
Genes