Health Sciences Research

Research Output

2020

Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults

Arenaza-Urquijo, E. M., Przybelski, S. A., MacHulda, M. M., Knopman, D. S., Lowe, V. J., Mielke, M. M., Reddy, A. L., Geda, Y. E., Jack, C. R., Petersen, R. C. & Vemuri, P., Apr 14 2020, In : Neurology. 94, 15, p. E1571-E1579

Research output: Contribution to journal › Article

Open Access
1 Scopus citations

Brain amyloid, cortical thickness, and changes in activities of daily living

Vassilaki, M., Aakre, J. A., Kremers, W. K., Lesnick, T. G., Mielke, M. M., Geda, Y. E., Machulda, M. M., Knopman, D. S., Butler, L., Traber, M., Vemuri, P., Lowe, V. J., Jack, C. R., Roberts, R. O. & Petersen, R. C., Jan 1 2020, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journal › Article

Open Access

Brain Regional Glucose Metabolism, Neuropsychiatric Symptoms, and the Risk of Incident Mild Cognitive Impairment: The Mayo Clinic Study of Aging

Krell-Roesch, J., Syrjanen, J. A., Vassilaki, M., Lowe, V. J., Vemuri, P., Mielke, M. M., Machulda, M. M., Stokin, G. B., Christianson, T. J., Kremers, W. K., Jack, C. R., Knopman, D. S., Petersen, R. C. & Geda, Y. E., 2020, (Accepted/In press) In : American Journal of Geriatric Psychiatry.

Research output: Contribution to journal › Article

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Dominguez-Valentin, M., Sampson, J. R., Seppälä, T. T., ten Broeke, S. W., Plazzer, J. P., Nakken, S., Engel, C., Aretz, S., Jenkins, M. A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Thomas, H., Evans, D. G., Burn, J., Greenblatt, M., Hovig, E., de Vos tot Nederveen Cappel, W. H., Sijmons, R. H. & 68 others, Bertario, L., Tibiletti, M. G., Cavestro, G. M., Lindblom, A., Della Valle, A., Lopez-Köstner, F., Gluck, N., Katz, L. H., Heinimann, K., Vaccaro, C. A., Büttner, R., Görgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Hüneburg, R., Knebel Doeberitz, M. V., Loeffler, M., Rahner, N., Schackert, H. K., Steinke-Lange, V., Schmiegel, W., Vangala, D., Pylvänäinen, K., Renkonen-Sinisalo, L., Hopper, J. L., Win, A. K., Haile, R. W., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Wadt, K., Therkildsen, C., Okkels, H., Ketabi, Z., Moreira, L., Sánchez, A., Serra-Burriel, M., Pineda, M., Navarro, M., Blanco, I., Green, K., Lalloo, F., Crosbie, E. J., Hill, J., Denton, O. G., Frayling, I. M., Rødland, E. A., Vasen, H., Mints, M., Neffa, F., Esperon, P., Alvarez, K., Kariv, R., Rosner, G., Pinero, T. A., Gonzalez, M. L., Kalfayan, P., Tjandra, D., Winship, I. M., Macrae, F., Möslein, G., Mecklin, J. P., Nielsen, M. & Møller, P., Jan 1 2020, In : Genetics in Medicine. 22, 1, p. 15-25 11 p.

Research output: Contribution to journal › Article

Open Access
25 Scopus citations

Challenges in returning results in a genomic medicine implementation study: the Return of Actionable Variants Empirical (RAVE) study

Kochan, D. C., Winkler, E., Lindor, N., Shaibi, G. Q., Olson, J., Caraballo, P. J., Freimuth, R., Pacyna, J. E., Breitkopf, C. R., Sharp, R. R. & Kullo, I. J., Dec 1 2020, In : npj Genomic Medicine. 5, 1, 19.

Research output: Contribution to journal › Article

Open Access

Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

Archambault, A. N., Su, Y. R., Jeon, J., Thomas, M., Lin, Y., Conti, D. V., Win, A. K., Sakoda, L. C., Lansdorp-Vogelaar, I., Peterse, E. F. P., Zauber, A. G., Duggan, D., Holowatyj, A. N., Huyghe, J. R., Brenner, H., Cotterchio, M., Bézieau, S., Schmit, S. L., Edlund, C. K., Southey, M. C. & 114 others, MacInnis, R. J., Campbell, P. T., Chang-Claude, J., Slattery, M. L., Chan, A. T., Joshi, A. D., Song, M., Cao, Y., Woods, M. O., White, E., Weinstein, S. J., Ulrich, C. M., Hoffmeister, M., Bien, S. A., Harrison, T. A., Hampe, J., Li, C. I., Schafmayer, C., Offit, K., Pharoah, P. D., Moreno, V., Lindblom, A., Wolk, A., Wu, A. H., Li, L., Gunter, M. J., Gsur, A., Keku, T. O., Pearlman, R., Bishop, D. T., Castellví-Bel, S., Moreira, L., Vodicka, P., Kampman, E., Giles, G. G., Albanes, D., Baron, J. A., Berndt, S. I., Brezina, S., Buch, S., Buchanan, D. D., Trichopoulou, A., Severi, G., Chirlaque, M. D., Sánchez, M. J., Palli, D., Kühn, T., Murphy, N., Cross, A. J., Burnett-Hartman, A. N., Chanock, S. J., de la Chapelle, A., Easton, D. F., Elliott, F., English, D. R., Feskens, E. J. M., FitzGerald, L. M., Goodman, P. J., Hopper, J. L., Hudson, T. J., Hunter, D. J., Jacobs, E. J., Joshu, C. E., Küry, S., Markowitz, S. D., Milne, R. L., Platz, E. A., Rennert, G., Rennert, H. S., Schumacher, F. R., Sandler, R. S., Seminara, D., Tangen, C. M., Thibodeau, S. N., Toland, A. E., van Duijnhoven, F. J. B., Visvanathan, K., Vodickova, L., Potter, J. D., Männistö, S., Weigl, K., Figueiredo, J., Martín, V., Larsson, S. C., Parfrey, P. S., Huang, W. Y., Lenz, H. J., Castelao, J. E., Gago-Dominguez, M., Muñoz-Garzón, V., Mancao, C., Haiman, C. A., Wilkens, L. R., Siegel, E., Barry, E., Younghusband, B., Van Guelpen, B., Harlid, S., Zeleniuch-Jacquotte, A., Liang, P. S., Du, M., Casey, G., Lindor, N. M., Le Marchand, L., Gallinger, S. J., Jenkins, M. A., Newcomb, P. A., Gruber, S. B., Schoen, R. E., Hampel, H., Corley, D. A., Hsu, L., Peters, U. & Hayes, R. B., Apr 2020, In : Gastroenterology. 158, 5, p. 1274-1286.e12

Research output: Contribution to journal › Article

4 Scopus citations

Differential effects of an electronic symptom monitoring intervention based on the age of patients with advanced cancer

Nipp, R. D., Horick, N. K., Deal, A. M., Rogak, L. J., Fuh, C., Greer, J. A., Dueck, A. C., Basch, E., Temel, J. S. & El-Jawahri, A., Jan 2020, In : Annals of Oncology. 31, 1, p. 123-130 8 p.

Research output: Contribution to journal › Article

4 Scopus citations

DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility

Pardini, B., Corrado, A., Paolicchi, E., Cugliari, G., Berndt, S. I., Bezieau, S., Bien, S. A., Brenner, H., Caan, B. J., Campbell, P. T., Casey, G., Chan, A. T., Chang-Claude, J., Cotterchio, M., Gala, M., Gallinger, S. J., Haile, R. W., Harrison, T. A., Hayes, R. B., Hoffmeister, M. & 21 others, Hopper, J. L., Hsu, L., Huyghe, J., Jenkins, M. A., Le Marchand, L., Lin, Y., Lindor, N. M., Nan, H., Newcomb, P. A., Ogino, S., Potter, J. D., Schoen, R. E., Slattery, M. L., White, E., Vodickova, L., Vymetalkova, V., Vodicka, P., Gemignani, F., Peters, U., Naccarati, A. & Landi, S., Jan 15 2020, In : International Journal of Cancer. 146, 2, p. 363-372 10 p.

Research output: Contribution to journal › Article

1 Scopus citations

Do the risks of Lynch syndrome-related cancers depend on the parent of origin of the mutation?

Gemechu, S. D., van Vliet, C. M., Win, A. K., Figueiredo, J. C., Le Marchand, L., Gallinger, S., Newcomb, P. A., Hopper, J. L., Lindor, N. M., Jenkins, M. A. & Dowty, J. G., Jul 1 2020, In : Familial Cancer. 19, 3, p. 215-222 8 p.

Research output: Contribution to journal › Article

Evaluation of NUC-1031: a first-in-class ProTide in biliary tract cancer

Arora, M., Bogenberger, J. M., Abdelrahman, A., Leiting, J. L., Chen, X., Egan, J. B., Kasimsetty, A., Lenkiewicz, E., Malasi, S., Uson, P. L. S., Nagalo, B. M., Zhou, Y., Salomao, M. A., Kosiorek, H. E., Braggio, E., Barrett, M. T., Truty, M. J. & Borad, M. J., Jun 1 2020, In : Cancer chemotherapy and pharmacology. 85, 6, p. 1063-1078 16 p.

Research output: Contribution to journal › Article

2 Scopus citations

Fewer gastrointestinal bleeds with ticagrelor and prasugrel compared with clopidogrel in patients with acute coronary syndrome following percutaneous coronary intervention

Abraham, N. S., Yang, E. H., Noseworthy, P., Inselman, J., Yao, X., Herrin, J., Sangaralingham, L. R., Ngufor, C. & Shah, N. D., 2020, (Accepted/In press) In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journal › Article

Open Access

Functional informed genome-wide interaction analysis of body mass index, diabetes and colorectal cancer risk

Xia, Z., Su, Y. R., Petersen, P., Qi, L., Kim, A. E., Figueiredo, J. C., Lin, Y., Nan, H., Sakoda, L. C., Albanes, D., Berndt, S. I., Bézieau, S., Bien, S., Buchanan, D. D., Casey, G., Chan, A. T., Conti, D. V., Drew, D. A., Gallinger, S. J., Gauderman, W. J. & 29 others, Giles, G. G., Gruber, S. B., Gunter, M. J., Hoffmeister, M., Jenkins, M. A., Joshi, A. D., Le Marchand, L., Lewinger, J. P., Li, L., Lindor, N. M., Moreno, V., Murphy, N., Nassir, R., Newcomb, P. A., Ogino, S., Rennert, G., Song, M., Wang, X., Wolk, A., Woods, M. O., Brenner, H., White, E., Slattery, M. L., Giovannucci, E. L., Chang-Claude, J., Pharoah, P. D. P., Hsu, L., Campbell, P. T. & Peters, U., May 1 2020, In : Cancer medicine. 9, 10, p. 3563-3573 11 p.

Research output: Contribution to journal › Article

Open Access

International standards for the analysis of quality-of-life and patient-reported outcome endpoints in cancer randomised controlled trials: recommendations of the SISAQOL Consortium

Setting International Standards in Analyzing Patient-Reported Outcomes and Quality of Life Endpoints Data Consortium, Feb 2020, In : The Lancet Oncology. 21, 2, p. e83-e96

Research output: Contribution to journal › Review article

4 Scopus citations

Investigation Into the Effects of Using Normal Distribution Theory Methodology for Likert Scale Patient-Reported Outcome Data From Varying Underlying Distributions Including Floor/Ceiling Effects

DeWees, T. A., Mazza, G. L., Golafshar, M. A. & Dueck, A. C., May 2020, In : Value in Health. 23, 5, p. 625-631 7 p.

Research output: Contribution to journal › Article

1 Scopus citations

Landscape of Health-Related Quality of Life in Patients With Early-Stage Pancreatic Cancer Receiving Adjuvant or Neoadjuvant Chemotherapy: A Systematic Literature Review

Macarulla, T., Hendifar, A. E., Li, C. P., Reni, M., Riess, H., Tempero, M. A., Dueck, A. C., Botteman, M. F., Deshpande, C. G., Lucas, E. J. & Oh, D. Y., Mar 1 2020, In : Pancreas. 49, 3, p. 393-407 15 p.

Research output: Contribution to journal › Article

2 Scopus citations

Longitudinal Toxicity over Time (ToxT) analysis to evaluate tolerability: a case study of lenalidomide in the CALGB 50401 (Alliance) trial

Thanarajasingam, G., Leonard, J. P., Witzig, T. E., Habermann, T. M., Blum, K. A., Bartlett, N. L., Flowers, C. R., Pitcher, B. N., Jung, S. H., Atherton, P. J., Tan, A., Novotny, P. J. & Dueck, A. C., Jun 2020, In : The Lancet Haematology. 7, 6, p. e490-e497

Research output: Contribution to journal › Review article

Long-term cardiac outcomes of patients with HER2-positive breast cancer treated in the adjuvant lapatinib and/or trastuzumab Treatment Optimization Trial

Eiger, D., Pondé, N. F., Agbor-Tarh, D., Moreno-Aspitia, A., Piccart, M., Hilbers, F. S., Werner, O., Chumsri, S., Dueck, A., Kroep, J. R., Gomez, H., Láng, I., Rodeheffer, R. J., Ewer, M. S., Suter, T. & de Azambuja, E., May 12 2020, In : British journal of cancer. 122, 10, p. 1453-1460 8 p.

Research output: Contribution to journal › Article

Medical Doctors and Dementia: A Longitudinal Study

Vassilaki, M., Syrjanen, J. A., Kremers, W. K., Hagen, P. T., Knopman, D. S., Mielke, M. M., Geda, Y. E., Alhurani, R. E., Machulda, M. M., Roberts, R. O. & Petersen, R. C., Jun 1 2020, In : Journal of the American Geriatrics Society. 68, 6, p. 1250-1255 6 p.

Research output: Contribution to journal › Article

Neuropsychological decline up to 20 years before incident mild cognitive impairment

Caselli, R. J., Langlais, B. T., Dueck, A. C., Chen, Y., Su, Y., Locke, D. E. C., Woodruff, B. K. & Reiman, E. M., Mar 1 2020, In : Alzheimer's and Dementia. 16, 3, p. 512-523 12 p.

Research output: Contribution to journal › Article

1 Scopus citations

Patient reported symptoms associated with quality of life during chemo- or immunotherapy for bladder cancer patients with advanced disease

Taarnhøj, G. A., Johansen, C., Lindberg, H., Basch, E., Dueck, A. & Pappot, H., 2020, (Accepted/In press) In : Cancer medicine.

Research output: Contribution to journal › Article

Open Access

Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

Papadimitriou, N., Dimou, N., Tsilidis, K. K., Banbury, B., Martin, R. M., Lewis, S. J., Kazmi, N., Robinson, T. M., Albanes, D., Aleksandrova, K., Berndt, S. I., Timothy Bishop, D., Brenner, H., Buchanan, D. D., Bueno-de-Mesquita, B., Campbell, P. T., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Ellingjord-Dale, M. & 62 others, Figueiredo, J. C., Gallinger, S. J., Giles, G. G., Giovannucci, E., Gruber, S. B., Gsur, A., Hampe, J., Hampel, H., Harlid, S., Harrison, T. A., Hoffmeister, M., Hopper, J. L., Hsu, L., María Huerta, J., Huyghe, J. R., Jenkins, M. A., Keku, T. O., Kühn, T., La Vecchia, C., Le Marchand, L., Li, C. I., Li, L., Lindblom, A., Lindor, N. M., Lynch, B., Markowitz, S. D., Masala, G., May, A. M., Milne, R., Monninkhof, E., Moreno, L., Moreno, V., Newcomb, P. A., Offit, K., Perduca, V., Pharoah, P. D. P., Platz, E. A., Potter, J. D., Rennert, G., Riboli, E., Sánchez, M. J., Schmit, S. L., Schoen, R. E., Severi, G., Sieri, S., Slattery, M. L., Song, M., Tangen, C. M., Thibodeau, S. N., Travis, R. C., Trichopoulou, A., Ulrich, C. M., van Duijnhoven, F. J. B., Van Guelpen, B., Vodicka, P., White, E., Wolk, A., Woods, M. O., Wu, A. H., Peters, U., Gunter, M. J. & Murphy, N., Dec 1 2020, In : Nature communications. 11, 1, 597.

Research output: Contribution to journal › Article

Open Access
1 Scopus citations

Potential impact of family history–based screening guidelines on the detection of early-onset colorectal cancer

Gupta, S., Bharti, B., Ahnen, D. J., Buchanan, D. D., Cheng, I. C., Cotterchio, M., Figueiredo, J. C., Gallinger, S. J., Haile, R. W., Jenkins, M. A., Lindor, N. M., Macrae, F. A., Le Marchand, L., Newcomb, P. A., Thibodeau, S. N., Win, A. K. & Martinez, M. E., Jul 1 2020, In : Cancer. 126, 13, p. 3013-3020 8 p.

Research output: Contribution to journal › Article

Prevalence of ideal cardiovascular health in a Central European community: results from the Kardiovize Brno 2030 Project

Medina-Inojosa, J. R., Vinciguerra, M., Maugeri, A., Kunzova, S., Sochor, O., Movsisyan, N., Geda, Y. E., Stokin, G. B. & Lopez-Jimenez, F., Mar 1 2020, In : European Journal of Preventive Cardiology. 27, 4, p. 441-443 3 p.

Research output: Contribution to journal › Letter

3 Scopus citations

Rapid Generation of Sustainable HER2-specific T-cell Immunity in Patients with HER2 Breast Cancer using a Degenerate HLA Class II Epitope Vaccine

Knutson, K. L., Block, M. S., Norton, N., Erskine, C. L., Hobday, T. J., Dietz, A. B., Padley, D., Gustafson, M. P., Puglisi-Knutson, D., Mangskau, T. K., Chumsri, S., Dueck, A. C., Karyampudi, L., Wilson, G. & Degnim, A. C., Mar 1 2020, In : Clinical Cancer Research. 26, 5, p. 1045-1053 9 p.

Research output: Contribution to journal › Article

Returning genomic results in a Federally Qualified Health Center: the intersection of precision medicine and social determinants of health

Shaibi, G. Q., Kullo, I. J., Singh, D. P., Hernandez, V., Sharp, R. R., Cuellar, I., De Filippis, E., Levey, S., Breitkopf, C. R., Mandarino, L. J., Yang, P., Thibodeau, S. N. & Lindor, N. M., Jan 1 2020, (Accepted/In press) In : Genetics in Medicine.

Research output: Contribution to journal › Article

1 Scopus citations

Returning results in the genomic era: Initial experiences of the emerge network

Wiesner, G. L., Rahm, A. K., Appelbaum, P., Aufox, S., Bland, S. T., Blout, C. L., Christensen, K. D., Chung, W. K., Clayton, E. W., Green, R. C., Harr, M. H., Henrikson, N., Hoell, C., Holm, I. A., Jarvik, G. P., Kullo, I. J., Lammers, P. E., Larson, E. B., Lindor, N. M., Marasa, M. & 12 others, Myers, M. F., Peterson, J. F., Prows, C. A., Ralston, J. D., Rasouly, H. M., Sharp, R. R., Smith, M. E., Van Driest, S. L., Williams, J. L., Williams, M. S., Wynn, J. & Leppig, K. A., May 2020, In : Journal of Personalized Medicine. 10, 2, 30.

Research output: Contribution to journal › Article

Open Access
2 Scopus citations

Risk of Gastrointestinal Bleeding Increases With Combinations of Antithrombotic Agents and Patient Age

Abraham, N. S., Noseworthy, P. A., Inselman, J., Herrin, J., Yao, X., Sangaralingham, L. R., Cornish, G., Ngufor, C. & Shah, N. D., Feb 2020, In : Clinical Gastroenterology and Hepatology. 18, 2, p. 337-346.e19

Research output: Contribution to journal › Article

4 Scopus citations

Risk of Recurrence and 10-Year Outcomes in Surgically Treated Nonmelanoma Skin Cancer in Cardiac and Liver Transplant Recipients

Yu, N. Y., Dewees, T. A., Alam, M., Ochoa, S. A., Mangold, A. R., Steidley, D. E., Vargas, H. E., Golafshar, M. A., Schild, S. E., Halyard, M. Y. & Patel, S. H., 2020, (Accepted/In press) In : American Journal of Clinical Oncology: Cancer Clinical Trials. 00003.

Research output: Contribution to journal › Article

Single-Institution Phase 1/2 Prospective Clinical Trial of Single-Fraction, High-Gradient Adjuvant Partial-Breast Irradiation for Hormone Sensitive Stage 0-I Breast Cancer

Kennedy, W. R., Thomas, M. A., Stanley, J. A., Luo, J., Ochoa, L. L., Clifton, K. K., Cyr, A. E., Margenthaler, J. A., DeWees, T. A., Price, A., Kashani, R., Green, O. & Zoberi, I., Jan 1 2020, (Accepted/In press) In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journal › Article

Social networks and obesity among Somali immigrants and refugees

Njeru, J. W., Wieland, M. L., Okamoto, J. M., Novotny, P. J., Breen-Lyles, M. K., Osman, A., Ahmed, Y. A., Nur, M. A., Nur, O. & Sia, I. G., Feb 17 2020, In : BMC Public Health. 20, 1, 238.

Research output: Contribution to journal › Article

Open Access

Successful Use of Intragastric Balloon Therapy as a Bridge to Heart Transplantation

Patel, N. J., Gómez, V., Steidley, D. E., Roust, L., Leoni Moreno, J. C., Abraham, N. S. & Pannala, R., Jan 1 2020, (Accepted/In press) In : Obesity Surgery. 30, 9, p. 3610-3614 5 p.

Research output: Contribution to journal › Article

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

ABCTB Investigators, HEBON Investigators, BCFR Investigators, OCGN Investigators, GEMO Study Collaborators, EMBRACE Collaborators & GC-HBOC Study Collaborators, Jul 1 2020, In : Genetic epidemiology. 44, 5, p. 442-468 27 p.

Research output: Contribution to journal › Article

Open Access