Health Sciences Research

Research Output 1979 2020

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Review article
2019

The Management of the Healed Scaphoid Malunion: What to Do?

Boe, C. C., Amadio, P. C. & Kakar, S., Jan 1 2019, In : Hand Clinics.

Research output: Contribution to journalReview article

Wrist
Osteotomy
Natural History
Biomechanical Phenomena
Anatomy
2 Citations (Scopus)

The role of oral magnesium supplements for the management of stable bronchial asthma: a systematic review and meta-analysis

Abuabat, F., AlAlwan, A., Masuadi, E., Murad, M. H., Jahdali, H. A. & Ferwana, M. S., Dec 1 2019, In : npj Primary Care Respiratory Medicine. 29, 1, 4.

Research output: Contribution to journalReview article

Open Access
Magnesium
Meta-Analysis
Asthma
Respiratory Hypersensitivity
Methacholine Chloride

Treatment of stable chronic obstructive pulmonary disease: Protocol for a systematic review and evidence map

Dobler, C. C., Farah, M. H., Morrow, A. S., Alsawas, M., Benkhadra, R., Hasan, B., Prokop, L. J., Wang, Z. & Murad, M. H., May 1 2019, In : BMJ open. 9, 5, e027935.

Research output: Contribution to journalReview article

Open Access
Chronic Obstructive Pulmonary Disease
Databases
Environmental Pollution
Nebulizers and Vaporizers
Research Ethics Committees

Two may be better than one: PD-1/PD-L1 blockade combination approaches in metastatic breast cancer

Page, D. B., Bear, H., Prabhakaran, S., Gatti-Mays, M. E., Thomas, A., Cobain, E., McArthur, H., Balko, J. M., Gameiro, S. R., Nanda, R., Gulley, J. L., Kalinsky, K., White, J., Litton, J., Chmura, S. J., Polley, M. Y., Vincent, B., Cescon, D. W., Disis, M. L., Sparano, J. A. & 2 others, Mittendorf, E. A. & Adams, S., Dec 1 2019, In : npj Breast Cancer. 5, 1, 34.

Research output: Contribution to journalReview article

Open Access
Blocking Antibodies
Breast Neoplasms
Radiotherapy
Ligands
Drug Therapy

Wide Awake Surgery as an Opportunity to Enhance Clinical Research

Festen-Schrier, V. J. M. M. & Amadio, P. C., Feb 1 2019, In : Hand Clinics. 35, 1, p. 93-96 4 p.

Research output: Contribution to journalReview article

Tendons
Tourniquets
Hand
Research
Sarcomeres
2018
1 Citation (Scopus)

Adjuvant Antiangiogenic Agents in Post-nephrectomy Renal Cell Carcinoma: A Systematic Review and Meta-analysis

Sonbol, M. B., Firwana, B., Hilal, T., Wang, Z., Almader-Douglas, D., Joseph, R. W. & Ho, T. H., Jun 1 2018, In : European Urology Oncology. 1, 2, p. 101-108 8 p.

Research output: Contribution to journalReview article

Angiogenesis Inhibitors
Nephrectomy
Renal Cell Carcinoma
Meta-Analysis
Disease-Free Survival

Age-related DNA methylation and hemostatic factors

De Andrade, M., Oct 25 2018, In : Blood. 132, 17, 1 p.

Research output: Contribution to journalReview article

Hemostatics
DNA Methylation
Epigenomics
Blood
Aging of materials
7 Citations (Scopus)

Altered mitochondrial function in insulin-deficient and insulin-resistant states

Ruegsegger, G. N., Creo, A. L., Cortes, T. M., Dasari, S. & Nair, K. S., Aug 31 2018, In : Journal of Clinical Investigation. 128, 9, p. 3671-3681 11 p.

Research output: Contribution to journalReview article

Insulin
Proteome
Reactive Oxygen Species
Organelle Biogenesis
Amino Acids
3 Citations (Scopus)

A new strategy to control and eradicate “undruggable” oncogenic K-RAS-driven pancreatic cancer: Molecular insights and core principles learned from developmental and evolutionary biology

Van Sciver, R. E., Lee, M. P., Lee, C. D., Lafever, A. C., Svyatova, E., Kanda, K., Colliver, A. L., Siewertsz Van Reesema, L. L., Tang-Tan, A. M., Zheleva, V., Bwayi, M. N., Bian, M., Schmidt, R. L., Matrisian, L. M., Petersen, G. M. & Tang, A. H., May 1 2018, In : Cancers. 10, 5, 142.

Research output: Contribution to journalReview article

Developmental Biology
Pancreatic Neoplasms
Neoplasms
Adenocarcinoma
Ubiquitin-Protein Ligases
2 Citations (Scopus)

Anticoagulation for stroke prevention in older adults with atrial fibrillation and comorbidity: Current evidence and treatment challenges

Sabbag, A., Yao, X., Siontis, K. C. & Noseworthy, P., Oct 1 2018, In : Korean Circulation Journal. 48, 10, p. 873-889 17 p.

Research output: Contribution to journalReview article

Atrial Fibrillation
Comorbidity
Stroke
Anticoagulants
Polypharmacy
4 Citations (Scopus)

A pulmonologist's guide to understanding network meta-analysis

Dobler, C. C., Wilson, M. & Murad, M. H., Jul 1 2018, In : European Respiratory Journal. 52, 1, 1800525.

Research output: Contribution to journalReview article

Pulmonologists
Network Meta-Analysis
1 Citation (Scopus)
Cohort Studies
Prospective Studies
Social Class
Health
Surveys and Questionnaires
4 Citations (Scopus)
decitabine
Azacitidine
Myelodysplastic Syndromes
Health Services
Public Health
2 Citations (Scopus)

Biomarker Clinical Trials in Lung Cancer: Design, Logistics, Challenges, and Practical Considerations

Le-Rademacher, J., Dahlberg, S., Lee, J. J., Adjei, A. & Mandrekar, S. J., Nov 1 2018, In : Journal of Thoracic Oncology. 13, 11, p. 1625-1637 13 p.

Research output: Contribution to journalReview article

Lung Neoplasms
Biomarkers
Clinical Trials
Precision Medicine
Standard of Care
2 Citations (Scopus)

Cardiovascular Concerns in BRCA1 and BRCA2 Mutation Carriers

Gast, K. C., Viscuse, P. V., Nowsheen, S., Haddad, T. C., Mutter, R., Wahner Hendrickson, A. E., Couch, F. J. & Ruddy, K. J., Feb 1 2018, In : Current Treatment Options in Cardiovascular Medicine. 20, 2, 18.

Research output: Contribution to journalReview article

Mutation
Radiotherapy
Thorax
Guidelines
Drug Therapy
26 Citations (Scopus)

Cellular senescence in brain aging and neurodegenerative diseases: Evidence and perspectives

Baker, D. J. & Petersen, R. C., Apr 2 2018, In : Journal of Clinical Investigation. 128, 4, p. 1208-1216 9 p.

Research output: Contribution to journalReview article

Cell Aging
Brain Diseases
Neurodegenerative Diseases
Cell Cycle Checkpoints
Parkinson Disease
35 Citations (Scopus)

Charter on Physician well-being

Thomas, L. R., Ripp, J. A. & West, C. P., Apr 17 2018, In : JAMA - Journal of the American Medical Association. 319, 15, p. 1541-1542 2 p.

Research output: Contribution to journalReview article

Physicians
Health Occupations
Systems Analysis
62 Citations (Scopus)

Clinical information extraction applications: A literature review

Wang, Y., Wang, L., Rastegar-Mojarad, M., Moon, S., Shen, F., Afzal, N., Liu, S., Zeng, Y., Mehrabi, S., Sohn, S. & Liu, H. D., Jan 1 2018, In : Journal of Biomedical Informatics. 77, p. 34-49 16 p.

Research output: Contribution to journalReview article

Information Storage and Retrieval
Electronic Health Records
Health
Publications
MEDLINE
8 Citations (Scopus)

Clinical use of intracoronary imaging. Part 1: Guidance and optimization of coronary interventions. An expert consensus document of the European Association of Percutaneous Cardiovascular Interventions

Räber, L., Mintz, G. S., Koskinas, K. C., Johnson, T. W., Holm, N. R., Onuma, Y., Radu, M. D., Joner, M., Yu, B., Jia, H., Meneveau, N., De La Torre Hernandez, J. M., Escaned, J., Hill, J., Prati, F., Colombo, A., Di Mario, C., Regar, E., Capodanno, D., Wijns, W. & 7 others, Byrne, R. A., Guagliumi, G., Serruys, P. W., Alfonso, F., Bhindi, R., Ali, Z. & Carter, R. E., Aug 1 2018, In : EuroIntervention. 14, 6, p. 656-677 22 p.

Research output: Contribution to journalReview article

Stents
Percutaneous Coronary Intervention
Optical Coherence Tomography
Thrombosis
Research
1 Citation (Scopus)

Commentary: Utilization trends of cervical disk replacement in the United States

Kerezoudis, P., Alvi, M. A., Goyal, A., Ubl, D. S., Meyer, J., Habermann, E. B., Currier, B. L. & Bydon, M., Jan 1 2018, In : Operative Neurosurgery. 15, 4, p. E40-E43

Research output: Contribution to journalReview article

5 Citations (Scopus)

Cytotoxicity of Local Anesthetics in Mesenchymal Stem Cells

Wu, T., Smith, J., Nie, H., Wang, Z., Erwin, P. J., van Wijnen, A. J. & Qu, W., Jan 1 2018, In : American Journal of Physical Medicine and Rehabilitation. 97, 1, p. 50-55 6 p.

Research output: Contribution to journalReview article

Local Anesthetics
Mesenchymal Stromal Cells
Anesthetics
Lidocaine
Mepivacaine
1 Citation (Scopus)

Data Registry on Experiences of Aging, Menopause, and Sexuality (DREAMS): A cohort profile

Faubion, S. S., Kapoor, E., Kling, J. M., Kuhle, C. L., Sood, R., Rullo, J. E., Thielen, J. M., Shuster, L. T., Rocca, W. A., Hilsaca, K. S. F., Mara, K. C., Schroeder, D. R. & Miller, V. M., Jan 1 2018, In : Maturitas. 107, p. 44-49 6 p.

Research output: Contribution to journalReview article

Sexuality
Menopause
Registries
Aging of materials
Health
21 Citations (Scopus)

Direct-to-Consumer Testing 2.0: Emerging Models of Direct-to-Consumer Genetic Testing

Allyse, M., Robinson, D. H., Ferber, M. J. & Sharp, R. R., Jan 1 2018, In : Mayo Clinic Proceedings. 93, 1, p. 113-120 8 p.

Research output: Contribution to journalReview article

Genetic Testing
Access to Information
History
Physicians
Direct-To-Consumer Screening and Testing
8 Citations (Scopus)

Does the chronic care model meet the emerging needs of people living with multimorbidity? A systematic review and thematic synthesis

Boehmer, K. R., Abu Dabrh, A. M., Gionfriddo, M. R., Erwin, P. & Montori, V. M., Feb 1 2018, In : PLoS One. 13, 2, e0190852.

Research output: Contribution to journalReview article

systematic review
Comorbidity
Medicine
synthesis
medicine
46 Citations (Scopus)

From genome-wide associations to candidate causal variants by statistical fine-mapping

Schaid, D. J., Chen, W. & Larson, N., Aug 1 2018, In : Nature Reviews Genetics. 19, 8, p. 491-504 14 p.

Research output: Contribution to journalReview article

Genome-Wide Association Study
Linkage Disequilibrium
Genetic Markers
Genome
Data Curation
9 Citations (Scopus)

GH therapy in childhood cancer survivors: A systematic review and meta-analysis

Tamhane, S., Sfeir, J. G., Kittah, N. E. N., Jasim, S., Chemaitilly, W., Cohen, L. E. & Murad, M. H., Jan 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 8, p. 2794-2801 8 p.

Research output: Contribution to journalReview article

Survivors
Meta-Analysis
Tumors
Medical problems
Neoplasms
10 Citations (Scopus)

Hypoglycemia Among Patients with Type 2 Diabetes: Epidemiology, Risk Factors, and Prevention Strategies

Silbert, R., Salcido-Montenegro, A., Rodriguez-Gutierrez, R., Katabi, A. & McCoy, R., Aug 1 2018, In : Current Diabetes Reports. 18, 8, 53.

Research output: Contribution to journalReview article

Hypoglycemia
Type 2 Diabetes Mellitus
Epidemiology
Insulin
Clinical Decision Support Systems
19 Citations (Scopus)

Hypothalamic–pituitary and growth disorders in survivors of childhood cancer: An endocrine society* clinical practice guideline

Sklar, C. A., Antal, Z., Chemaitilly, W., Cohen, L. E., Follin, C., Meacham, L. R. & Murad, M. H., Jan 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 8, p. 2761-2784 24 p.

Research output: Contribution to journalReview article

Endocrine Gland Neoplasms
Growth Disorders
Oncology
Practice Guidelines
Radiation
45 Citations (Scopus)

Imaging for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

Roberts, L. R., Sirlin, C. B., Zaiem, F., Almasri, J., Prokop, L. J., Heimbach, J. K., Murad, M. H. & Mohammed, K., Jan 1 2018, In : Hepatology. 67, 1, p. 401-421 21 p.

Research output: Contribution to journalReview article

Meta-Analysis
Hepatocellular Carcinoma
Magnetic Resonance Imaging
Tomography
Fibrosis
31 Citations (Scopus)

Impact of balloon guide catheter on technical and clinical outcomes: A systematic review and meta-Analysis

Brinjikji, W., Starke, R. M., Murad, M. H., Fiorella, D., Pereira, V. M., Goyal, M. & Kallmes, D. F., Apr 1 2018, In : Journal of NeuroInterventional Surgery. 10, 4, p. 335-339 5 p.

Research output: Contribution to journalReview article

Meta-Analysis
Catheters
Thrombectomy
Cerebral Infarction
Stroke
9 Citations (Scopus)

Innovative Use of Novel Biomarkers to Improve the Safety of Renally Eliminated and Nephrotoxic Medications

Barreto, E. F., Rule, A. D., Voils, S. A. & Kane-Gill, S. L., Aug 1 2018, In : Pharmacotherapy. 38, 8, p. 794-803 10 p.

Research output: Contribution to journalReview article

Biomarkers
Kidney
Safety
Cystatin C
Tissue Inhibitor of Metalloproteinase-2
1 Citation (Scopus)

Key Ethical Issues in Prenatal Genetics: An Overview

Farrell, R. M. & Allyse, M., Mar 1 2018, In : Obstetrics and Gynecology Clinics of North America. 45, 1, p. 127-141 15 p.

Research output: Contribution to journalReview article

Family Health
Ethics
Health Personnel
Community Health Services
Technology
17 Citations (Scopus)

Large-vessel giant cell arteritis: Diagnosis, monitoring and management

Koster, M., Matteson, E. L. & Warrington, K. J., Feb 1 2018, In : Rheumatology (United Kingdom). 57, p. ii32-ii42

Research output: Contribution to journalReview article

Giant Cell Arteritis
Biological Therapy
Magnetic Resonance Angiography
Delayed Diagnosis
Vasculitis
4 Citations (Scopus)

Leukocyte Telomere Length and Pancreatic Cancer Risk: Updated Epidemiologic Review

Antwi, S. & Petersen, G. M., Mar 1 2018, In : Pancreas. 47, 3, p. 265-271 7 p.

Research output: Contribution to journalReview article

Telomere
Pancreatic Neoplasms
Leukocytes
Case-Control Studies
Telomere Homeostasis
23 Citations (Scopus)

Management of tandem occlusions in acute ischemic stroke-intracranial versus extracranial first and extracranial stenting versus angioplasty alone: A systematic review and meta-Analysis

Wilson, M. P., Murad, M. H., Krings, T., Pereira, V. M., O'Kelly, C., Rempel, J., Hilditch, C. A. & Brinjikji, W., Aug 1 2018, In : Journal of NeuroInterventional Surgery. 10, 8, p. 721-728 8 p.

Research output: Contribution to journalReview article

Angioplasty
Meta-Analysis
Stroke
Thrombectomy
Equipment and Supplies
2 Citations (Scopus)

Meta-Analysis Comparing Frequency of Overweight Versus Normal Weight in Patients With New-Onset Heart Failure

Krittanawong, C., Tunhasiriwet, A., Wang, Z., Zhang, H. J., Prokop, L. J., Chirapongsathorn, S., Sun, T., Kitai, T. & Tang, W. H. W., Apr 1 2018, In : American Journal of Cardiology. 121, 7, p. 836-843 8 p.

Research output: Contribution to journalReview article

Meta-Analysis
Heart Failure
Weights and Measures
Obesity
MEDLINE
1 Citation (Scopus)

Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models

Wongjarupong, N., Negron-Ocasio, G. M., Chaiteerakij, R., Addissie, B. D., Mohamed, E. A., Mara, K. C., Harmsen, W. S., Theobald, J. P., Peters, B. E., Balsanek, J. G., Ward, M. M., Giama, N. H., Venkatesh, S. K., Harnois, D., Charlton, M. R., Yamada, H., Algeciras-Schimnich, A., Snyder, M. R., Therneau, T. M. & Roberts, L. R., Mar 28 2018, In : World Journal of Gastroenterology. 24, 12, p. 1321-1331 11 p.

Research output: Contribution to journalReview article

alpha-Fetoproteins
Tumor Biomarkers
Hepatocellular Carcinoma
Transplants
Biomarkers
9 Citations (Scopus)

Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma

Deleon, T. T., Ahn, D., Bogenberger, J. M., Anastasiadis, P. Z., Arora, M., Ramanathan, R. K., Aqel, B. A., Vasmatzis, G., Truty, M., Oklu, R., Bekaii-Saab, T. & Borad, M. J., Mar 1 2018, In : Future Oncology. 14, 6, p. 553-566 14 p.

Research output: Contribution to journalReview article

Biliary Tract Neoplasms
Hepatocellular Carcinoma
Neoplasms
Biomarkers
Therapeutics
2 Citations (Scopus)

Outcomes of critical illness: What is meaningful?

Gajic, O., Ahmad, S. R., Wilson, M. & Kaufman, D. A., Jan 1 2018, In : Current Opinion in Critical Care. 24, 5, p. 394-400 7 p.

Research output: Contribution to journalReview article

Critical Illness
Survivors
Patient Preference
Critical Care
Quality Improvement
5 Citations (Scopus)

Personal Perspective: What's in a name: Are menopausal "hot flashes" a symptom of menopause or a manifestation of neurovascular dysregulation?

Miller, V. M., Kling, J. M., Files, J. A., Joyner, M. J., Kapoor, E., Moyer, A., Rocca, W. A. & Faubion, S. S., Jun 1 2018, In : Menopause. 25, 6, p. 700-703 4 p.

Research output: Contribution to journalReview article

Hot Flashes
Menopause
Names
Ovariectomy
Cognition
13 Citations (Scopus)

Potentially Modifiable Risk Factors for Long-Term Cognitive Impairment After Critical Illness: A Systematic Review

Sakusic, A., O'Horo, J. C., Dziadzko, M., Volha, D., Ali, R., Singh, T. D., Kashyap, R., Farrell, A. M., Fryer, J. D., Petersen, R. C., Gajic, O. & Rabinstein, A., Jan 1 2018, In : Mayo Clinic Proceedings. 93, 1, p. 68-82 15 p.

Research output: Contribution to journalReview article

Critical Illness
Intensive Care Units
Delirium
Critical Care
Survivors
13 Citations (Scopus)

Projected Costs of Informal Caregiving for Cardiovascular Disease: 2015 to 2035: A Policy Statement From the American Heart Association

American Heart Association, May 8 2018, In : Circulation. 137, 19, p. e558-e577

Research output: Contribution to journalReview article

Open Access
Cardiovascular Diseases
Costs and Cost Analysis
Cost of Illness
Home Health Aides
Stroke

Reporting of patient characteristics and stratification factors in phase 3 trials investigating first-line systemic treatment of metastatic colorectal cancer: A systematic review

Goey, K. K. H., Mahmoud, R., Sørbye, H., Glimelius, B., Köhne, C. H., Sargent, D. J., Punt, C. J. A., van Oijen, M. G. H. & Koopman, M., Jun 1 2018, In : European Journal of Cancer. 96, p. 115-124 10 p.

Research output: Contribution to journalReview article

Colorectal Neoplasms
Therapeutics
Adjuvant Chemotherapy
Leukocyte Count
L-Lactate Dehydrogenase
1 Citation (Scopus)

Research on human embryos and reproductive materials: Revisiting canadian law and policy

Ogbogu, U., Zarzeczny, A., Baltz, J., Bedford, P., Du, J., Hyun, I., Jaafar, Y., Jurisicova, A., Kleiderman, E., Koukio, Y., Knoppers, B. M., Leader, A., Master, Z., Nguyen, M. T., Noohi, F., Ravitsky, V. & Toews, M., Jan 1 2018, In : Healthcare Policy. 13, 3, p. 10-19 10 p.

Research output: Contribution to journalReview article

Embryo Research
Canada
Stem Cell Research
Genetic Research
Policy Making
63 Citations (Scopus)

Standards and Guidelines for Validating Next-Generation Sequencing Bioinformatics Pipelines: A Joint Recommendation of the Association for Molecular Pathology and the College of American Pathologists

Roy, S., Coldren, C., Karunamurthy, A., Kip, N. S., Klee, E. W., Lincoln, S. E., Leon, A., Pullambhatla, M., Temple-Smolkin, R. L., Voelkerding, K. V., Wang, C. & Carter, A. B., Jan 1 2018, In : Journal of Molecular Diagnostics. 20, 1, p. 4-27 24 p.

Research output: Contribution to journalReview article

Molecular Pathology
Computational Biology
Joints
Guidelines
Patient Care
7 Citations (Scopus)

Statistical analysis of patient-reported outcome data in randomised controlled trials of locally advanced and metastatic breast cancer: a systematic review

Setting International Standards in Analyzing Patient-Reported Outcomes and Quality of Life Endpoints Data Consortium (SISAQOL), Sep 1 2018, In : The Lancet Oncology. 19, 9, p. e459-e469

Research output: Contribution to journalReview article

Randomized Controlled Trials
Breast Neoplasms
Quality of Life
Patient Reported Outcome Measures
PubMed
14 Citations (Scopus)

Systematic review and network meta-analysis: first- and second-line biologic therapies for moderate-severe Crohn's disease

Singh, S., Fumery, M., Sandborn, W. J. & Murad, M. H., Aug 1 2018, In : Alimentary Pharmacology and Therapeutics. 48, 4, p. 394-409 16 p.

Research output: Contribution to journalReview article

Biological Therapy
Crohn Disease
Remission Induction
Tumor Necrosis Factor-alpha
Maintenance
34 Citations (Scopus)

Systematic review with network meta-analysis: first- and second-line pharmacotherapy for moderate-severe ulcerative colitis

Singh, S., Fumery, M., Sandborn, W. J. & Murad, M. H., Jan 1 2018, In : Alimentary Pharmacology and Therapeutics. 47, 2, p. 162-175 14 p.

Research output: Contribution to journalReview article

Remission Induction
Ulcerative Colitis
Drug Therapy
Tumor Necrosis Factor-alpha
Biological Products
2 Citations (Scopus)

Testosterone therapy and venous thromboembolism: A systematic review and meta-analysis

Houghton, D. E., Alsawas, M., Barrioneuvo, P., Tello, M., Farah, W., Beuschel, B., Prokop, L. J., Layton, J. B., Murad, M. H. & Moll, S., Dec 1 2018, In : Thrombosis Research. 172, p. 94-103 10 p.

Research output: Contribution to journalReview article

Venous Thromboembolism
Testosterone
Meta-Analysis
Confidence Intervals
Observational Studies
8 Citations (Scopus)

The cortisol stress response induced by surgery: A systematic review and meta-analysis

Prete, A., Yan, Q., Al-Tarrah, K., Akturk, H. K., Prokop, L. J., Alahdab, F., Foster, M. A., Lord, J. M., Karavitaki, N., Wass, J. A., Murad, M. H., Arlt, W. & Bancos, I., Nov 1 2018, In : Clinical Endocrinology. 89, 5, p. 554-567 14 p.

Research output: Contribution to journalReview article

Hydrocortisone
Meta-Analysis
Etomidate
Minimally Invasive Surgical Procedures
General Anesthesia