General Thoracic Surgery

Research output

Research output per year 1991 2009 2011 2014 2016 2017 2018 2020 2021 2022 2023 2024

• 222 Article
• 25 Comment/debate
• 17 Review article
• 4 Editorial
• 4 More
  • 4 Letter

Research output per year

Research output per year

Search results

• 2024

  An in-silico analysis reveals further evidence of an aggressive subset of lung carcinoids sharing molecular features of high-grade neuroendocrine neoplasms

  Pelosi, G., Melocchi, V., Dama, E., Hofman, P., De Luca, M., Albini, A., Gemelli, M., Ricotta, R., Papotti, M., La Rosa, S., Uccella, S., Harari, S., Sonzogni, A., Asiedu, M. K., Wigle, D. A. & Bianchi, F., Feb 2024, In: Experimental and Molecular Pathology. 135, 104882.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Carcinoid Tumor 100%
  • Computer Simulation 82%
  • Mutation 74%
  • Lung 47%
  • Small Cell Lung Carcinoma 43%

• Completion of accrual for Thoracic Surgical Oncology Group 102: One small step forward for thoracic clinical trials

  Thoracic Surgical Oncology Group 102 Investigators & Thoracic Surgical Oncology Group Executive Board, 2024, (Accepted/In press) In: Journal of Thoracic and Cardiovascular Surgery.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Esophagectomy Enhanced Recovery After Surgery Initiative Results in Improved Outcomes

  Sims, C. R., Abou Chaar, M. K., Kerfeld, M. H., Cassivi, S., Hofer, R. E., Nichols, F. C., Reisenauer, J., Saddoughi, S. S., Shen, K. R., Stewart, T. M., Tapias, L. F., Wigle, D. A. & Blackmon, S. H., Apr 2024, In: Annals of Thoracic Surgery. 117, 4, p. 847-857 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Lobectomy, segmentectomy, or wedge resection for peripheral clinical T1aN0 non–small cell lung cancer: A post hoc analysis of CALGB 140503 (Alliance)

  Altorki, N., Wang, X., Damman, B., Mentlick, J., Landreneau, R., Wigle, D., Jones, D. R., Conti, M., Ashrafi, A. S., Liberman, M., de Perrot, M., Mitchell, J. D., Keenan, R., Bauer, T., Miller, D. & Stinchcombe, T. E., Jan 2024, In: Journal of Thoracic and Cardiovascular Surgery. 167, 1, p. 338-347.e1

  Research output: Contribution to journal › Article › peer-review

  • Segmental Mastectomy 100%
  • Non-Small Cell Lung Carcinoma 78%
  • Survival 48%
  • Forced Expiratory Volume 47%
  • Recurrence 33%
• 2023

  Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers (Nature Genetics, (2020), 52, 3, (342-352), 10.1038/s41588-019-0557-x)

  PCAWG Consortium, May 2023, In: Nature Genetics. 55, 5, p. 892 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Author Correction: Patterns of somatic structural variation in human cancer genomes (Nature, (2020), 578, 7793, (112-121), 10.1038/s41586-019-1913-9)

  PCAWG-Structural Variation Working Group & PCAWG Consortium, Feb 16 2023, In: Nature. 614, 7948, p. E38

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing (Nature Genetics, (2020), 52, 3, (331-341), 10.1038/s41588-019-0576-7)

  PCAWG-Structural Variation Working Group & PCAWG Consortium, Jun 2023, In: Nature Genetics. 55, 6, p. 1076 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Chromothripsis 100%
  • Whole Genome Sequencing 67%
  • Genome 39%
  • Neoplasms 18%

• Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers (Nature Genetics, (2020), 52, 3, (342-352), 10.1038/s41588-019-0557-x)

  PCAWG Consortium, Jun 2023, In: Nature Genetics. 55, 6, p. 1078 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Mitochondrial Genome 100%
  • Genome 53%
  • Neoplasms 25%

• Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes (Nature, (2020), 578, 7793, (102-111), 10.1038/s41586-020-1965-x)

  PCAWG Drivers and Functional Interpretation Working Group, PCAWG-Structural Variation Working Group & PCAWG Consortium, Feb 16 2023, In: Nature. 614, 7948, p. E40

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition (Nature Genetics, (2020), 52, 3, (306-319), 10.1038/s41588-019-0562-0)

  PCAWG-Structural Variation Working Group & PCAWG Consortium, Jun 2023, In: Nature Genetics. 55, 6, p. 1080 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Genome 100%
  • Medicine 53%
  • Neoplasms 47%
  • Baltimore 47%
  • Quebec 44%

• Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer (Nature Genetics, (2020), 52, 3, (294-305), 10.1038/s41588-019-0564-y)

  PCAWG-Structural Variation Working Group & PCAWG Consortium, Jun 2023, In: Nature Genetics. 55, 6, p. 1079 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Chromatin 100%
  • Genome 76%
  • Neoplasms 36%

• Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes (Nature Biotechnology, (2020), 38, 3, (288-292), 10.1038/s41587-019-0360-3)

  PCAWG Technical Working Group & PCAWG Consortium, Apr 2023, In: Nature biotechnology. 41, 4, p. 577 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Author Correction: Pan-cancer analysis of whole genomes (Nature, (2020), 578, 7793, (82-93), 10.1038/s41586-020-1969-6)

  The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 16 2023, In: Nature. 614, 7948, p. E39

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Genome 100%
  • Neoplasms 47%

• Author Correction: The evolutionary history of 2,658 cancers (Nature, (2020), 578, 7793, (122-128), 10.1038/s41586-019-1907-7)

  PCAWG Evolution & Heterogeneity Working Group & PCAWG Consortium, Feb 16 2023, In: Nature. 614, 7948, p. E42

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Author Correction: Genomic basis for RNA alterations in cancer (Nature, (2020), 578, 7793, (129-136), 10.1038/s41586-020-1970-0)

  PCAWG Transcriptome Core Group, PCAWG Transcriptome Working Group & PCAWG Consortium, Feb 16 2023, In: Nature. 614, 7948, p. E37

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Author Correction: The repertoire of mutational signatures in human cancer (Nature, (2020), 578, 7793, (94-101), 10.1038/s41586-020-1943-3)

  PCAWG Mutational Signatures Working Group & PCAWG Consortium, Feb 16 2023, In: Nature. 614, 7948, p. E41

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Author Correction: The landscape of viral associations in human cancers (Nature Genetics, (2020), 52, 3, (320-330), 10.1038/s41588-019-0558-9)

  PCAWG Pathogens & PCAWG Consortium, Jun 2023, In: Nature Genetics. 55, 6, p. 1077 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Genome 100%
  • Neoplasms 47%
  • Germany 32%
  • Infections 17%

• Determinants of Long-term Survival Decades After Esophagectomy for Esophageal Cancer

  Abou Chaar, M. K., Godin, A., Harmsen, W. S., Wzientek, C., Saddoughi, S. A., Hallemeier, C. L., Cassivi, S. D., Nichols, F. C., Reisenauer, J. S., Shen, K. R., Tapias, L. F., Wigle, D. A. & Blackmon, S. H., Nov 2023, In: Annals of Thoracic Surgery. 116, 5, p. 1036-1044 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Esophagectomy 100%
  • Esophageal Neoplasms 87%
  • Survival 47%
  • Recurrence 30%
  • Disease-Free Survival 20%

• Impact of FDG PET Standardized Uptake Value in Resected Clinical Stage IA Non-Small Cell Lung Cancer

  Tapias, L. F., Shen, R., Cassivi, S. D., Reisenauer, J. S., Lunn, B. W., Lechtenberg, B. J., Nichols, F. C., Wigle, D. A. & Blackmon, S. H., 2023, (Accepted/In press) In: Annals of Thoracic Surgery.

  Research output: Contribution to journal › Article › peer-review

  • Positron-Emission Tomography 100%
  • Non-Small Cell Lung Carcinoma 96%
  • Recurrence 26%
  • Survival 25%
  • Neoplasms 14%

• Lobar or Sublobar Resection for Peripheral Stage IA Non-Small-Cell Lung Cancer

  Altorki, N., Wang, X., Kozono, D., Watt, C., Landrenau, R., Wigle, D., Port, J., Jones, D. R., Conti, M., Ashrafi, A. S., Liberman, M., Yasufuku, K., Yang, S., Mitchell, J. D., Pass, H., Keenan, R., Bauer, T., Miller, D., Kohman, L. J., Stinchcombe, T. E., & 1 othersVokes, E., 2023, In: New England Journal of Medicine. 388, 6, p. 489-498 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Non-Small Cell Lung Carcinoma 100%
  • Disease-Free Survival 70%
  • Confidence Intervals 66%
  • Recurrence 42%
  • Survival 41%

• Preoperative Type and Screen Before General Thoracic Surgery: A Nomogram to Reduce Unnecessary Tests

  Abdelsattar, Z. M., Joshi, V., Cassivi, S., Kor, D., Shen, K. R., Nichols, F., Allen, M., Blackmon, S. H. & Wigle, D., Feb 2023, In: Annals of Thoracic Surgery. 115, 2, p. 519-525 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nomograms 100%
  • Thoracic Surgery 73%
  • Blood Transfusion 44%
  • Hemoglobins 18%
  • Datasets 18%

• Progress in genome-inspired treatment decisions for multifocal lung adenocarcinoma

  Powell, C. L., Saddoughi, S. A. & Wigle, D. A., 2023, In: Expert Review of Respiratory Medicine. 17, 11, p. 1009-1021 13 p.

  Research output: Contribution to journal › Review article › peer-review

• Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers (Nature Genetics, (2020), 52, 3, (342-352), 10.1038/s41588-019-0557-x)

  PCAWG Consortium, May 2023, In: Nature Genetics. 55, 5, p. 893 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Pulmonary Open, Robotic, and Thoracoscopic Lobectomy (PORTaL) Study: Survival Analysis of 6646 Cases

  Kent, M. S., Hartwig, M. G., Vallières, E., Abbas, A. E., Cerfolio, R. J., Dylewski, M. R., Fabian, T., Herrera, L. J., Jett, K. G., Lazzaro, R. S., Meyers, B., Reddy, R. M., Reed, M. F., Rice, D. C., Ross, P., Sarkaria, I. S., Schumacher, L. Y., Spier, L. N., Tisol, W. B., Wigle, D. A., & 1 othersZervos, M., Jun 1 2023, In: Annals of surgery. 277, 6, p. 1002-1009 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Robotics 100%
  • Survival Analysis 92%
  • Lung 51%
  • Survival 39%
  • Lung Neoplasms 18%

• Pulmonary Open, Robotic, and Thoracoscopic Lobectomy (PORTaL) Study: An Analysis of 5721 Cases

  Kent, M. S., Hartwig, M. G., Vallières, E., Abbas, A. E., Cerfolio, R. J., Dylewski, M. R., Fabian, T., Herrera, L. J., Jett, K. G., Lazzaro, R. S., Meyers, B., Mitzman, B. A., Reddy, R. M., Reed, M. F., Rice, D. C., Ross, P., Sarkaria, I. S., Schumacher, L. Y., Tisol, W. B., Wigle, D. A., & 1 othersZervos, M., Mar 1 2023, In: Annals of surgery. 277, 3, p. 528-533 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Video-Assisted Thoracic Surgery 100%
  • Robotics 91%
  • Lung 46%
  • Length of Stay 18%
  • Propensity Score 17%

• Risk stratification of postoperative cardiopulmonary toxicity after trimodality therapy for esophageal cancer

  Kowalchuk, R. O., Spears, G. M., Morris, L. K., Owen, D., Yoon, H. H., Jethwa, K., Chuong, M. D., Ferris, M. J., Haddock, M. G., Hallemeier, C. L., Wigle, D., Lin, S. H. & Merrell, K. W., Feb 9 2023, In: Frontiers in Oncology. 13, 1081024.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Esophageal Neoplasms 100%
  • Survival 33%
  • Esophagectomy 28%
  • Radiotherapy 16%
  • Proton Therapy 16%

• The diagnostic utility of inspiratory-expiratory radiography for the assessment of phrenic nerve palsy associated with brachial plexus injury

  Crowe, C. S., Pulos, N., Spinner, R. J., Bishop, A. T., Wigle, D. A. & Shin, A. Y., Sep 2023, In: Acta Neurochirurgica. 165, 9, p. 2589-2596 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Arm Injuries 100%
  • Phrenic Nerve 90%
  • Brachial Plexus 87%
  • Paralysis 69%
  • Radiography 69%

• The Utility of the Omentum Flap for Complex Intrathoracic Problems

  Kreutz-Rodrigues, L., Gibreel, W., Moran, S. L., Mardini, S., Bite, U., Stulak, J. M., Wigle, D., Pochettino, A. & Bakri, K., Feb 2023, In: Plastic Surgery. 31, 1, p. 17-23 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Omentum 100%
  • Thoracic Wall 87%
  • Heart-Assist Devices 47%
  • Vasoconstrictor Agents 44%
  • Surgical Flaps 33%
• 2022

  Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower (Nature Communications, (2020), 11, 1, (734), 10.1038/s41467-019-13929-1)

  PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2022, In: Nature communications. 13, 1, 7571.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • impact tests 100%
  • genome 79%
  • cancer 71%
  • Communication 69%
  • communication 63%

• Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations (Nature Communications, (2020), 11, 1, (736), 10.1038/s41467-019-13885-w)

  PCAWG Transcriptome Working Group, PCAWG-Structural Variation Working Group & PCAWG Consortium, Dec 1 2022, In: Nature communications. 13, 1, 7572.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • genome 100%
  • Gene Rearrangement 89%
  • genes 89%
  • cancer 71%
  • Communication 69%

• Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns (Nature Communications, (2020), 11, 1, (728), 10.1038/s41467-019-13825-8)

  PCAWG Tumor Subtypes and Clinical Translation Working Group & PCAWG Consortium, Dec 2022, In: Nature communications. 13, 1, 7573.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Deep Learning 100%
  • genome 94%
  • passengers 93%
  • document markup languages 86%
  • mutations 84%

• Author Correction: Inferring structural variant cancer cell fraction (Nature Communications, (2020), 11, 1, (730), 10.1038/s41467-020-14351-8)

  PCAWG Evolution and Heterogeneity Working Group & PCAWG Consortium, Dec 1 2022, In: Nature communications. 13, 1, 7568.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • genome 100%
  • cancer 71%
  • Communication 69%
  • document markup languages 68%
  • communication 63%

• Author Correction: Integrative pathway enrichment analysis of multivariate omics data (Nature Communications, (2020), 11, 1, (735), 10.1038/s41467-019-13983-9)

  PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2022, In: Nature communications. 13, 1, 7570.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • genome 100%
  • document markup languages 91%
  • cancer 71%
  • Communication 69%
  • communication 63%

• Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours (Nature Communications, (2020), 11, 1, (737), 10.1038/s41467-019-14052-x)

  PCAWG Consortium, Dec 2022, In: Nature communications. 13, 1, 7569.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • genome 100%
  • document markup languages 91%
  • tumors 73%
  • cancer 71%
  • Communication 69%

• Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Nature Communications, (2020), 11, 1, (733), 10.1038/s41467-019-13824-9)

  PCAWG-Structural Variation Working Group & PCAWG Consortium, Dec 1 2022, In: Nature communications. 13, 1, 7574.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • telomeres 100%
  • genome 76%
  • document markup languages 70%
  • footprints 66%
  • Telomere 64%

• Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes (Nature Communications, (2020), 11, 1, (729), 10.1038/s41467-020-14367-0)

  PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2022, In: Nature communications. 13, 1, 7566.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig (Nature Communications, (2020), 11, 1, (731), 10.1038/s41467-020-14352-7)

  PCAWG Evolution and Heterogeneity Working Group & PCAWG Consortium, Dec 1 2022, In: Nature communications. 13, 1, 7567.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • genome 100%
  • document markup languages 91%
  • mutations 89%
  • cancer 71%
  • Communication 69%

• Challenges to Randomized Trials in Adult and Congenital Cardiac and Thoracic Surgery

  Gaudino, M., Chikwe, J., Bagiella, E., Fremes, S., Jones, D. R., Meyers, B., Newburger, J. W., Ohye, R. G., Sassalos, P., Wigle, D. & Di Franco, A., May 2022, In: Annals of Thoracic Surgery. 113, 5, p. 1409-1418 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Thoracic Surgery 100%
  • Surgeons 78%
  • Learning Curve 64%
  • Medicine 40%
  • Research Personnel 38%

• Chest wall resection for breast cancer: 21st century Mayo clinic experience

  Durgan, D. M., De La Cruz Ku, G., Thomas, M., Pockaj, B. A., McLaughlin, S. A., Casey, W. J., Vijayasekaran, A., Wigle, D., Cheville, J. C., Tonneson, J., Hoskin, T. L. & Jakub, J. W., Nov 2022, In: Journal of Surgical Oncology. 126, 6, p. 962-969 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Thoracic Wall 100%
  • Breast Neoplasms 59%
  • Recurrence 45%
  • Sternum 33%
  • Ribs 29%

• Pembrolizumab in Combination with Neoadjuvant Chemoradiotherapy for Patients with Resectable Adenocarcinoma of the Gastroesophageal Junction

  Zhu, M., Chen, C., Foster, N. R., Hartley, C., Mounajjed, T., Salomao, M. A., Fruth, B. F., Beamer, S. E., Kim, Y., Harrington, S. M., Pitot, H. C., Sanhueza, C. T., Feng, Y., Herrmann, J., McWilliams, R. R., Lucien, F., Huang, B. Q., Ma, W. W., Bekaii-Saab, T. S., Dong, H., & 5 othersWigle, D., Ahn, D. H., Hallemeier, C. L., Blackmon, S. & Yoon, H. H., Jul 15 2022, In: Clinical Cancer Research. 28, 14, p. 3021-3031 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • pembrolizumab 100%
  • Esophagogastric Junction 91%
  • Chemoradiotherapy 75%
  • Adenocarcinoma 55%
  • Tumor Microenvironment 22%

• Perioperative outcomes of pulmonary resection after neoadjuvant pembrolizumab in patients with non–small cell lung cancer

  Tong, B. C., Gu, L., Wang, X., Wigle, D. A., Phillips, J. D., Harpole, D. H., Klapper, J. A., Sporn, T., Ready, N. E. & D'Amico, T. A., Feb 2022, In: Journal of Thoracic and Cardiovascular Surgery. 163, 2, p. 427-436 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • pembrolizumab 100%
  • Non-Small Cell Lung Carcinoma 63%
  • Lung 38%
  • Thyroiditis 9%
  • Death Domain Receptors 8%

• Rates of Guideline-Concordant Surgery and Adjuvant Chemotherapy among Patients with Early-Stage Lung Cancer in the US ALCHEMIST Study (Alliance A151216)

  Kehl, K. L., Zahrieh, D., Yang, P., Hillman, S. L., Tan, A. D., Sands, J. M., Oxnard, G. R., Gillaspie, E. A., Wigle, D., Malik, S., Stinchcombe, T. E., Ramalingam, S. S., Kelly, K., Govindan, R., Mandrekar, S. J., Osarogiagbon, R. U. & Kozono, D., May 2022, In: JAMA Oncology. 8, 5, p. 717-728 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adjuvant Chemotherapy 100%
  • Lung Neoplasms 78%
  • Non-Small Cell Lung Carcinoma 75%
  • Guidelines 63%
  • Lymph Node Excision 55%

• Serial evaluation of segmental esophageal reconstruction using a polyurethane scaffold in a pig model

  Sarrafian, T. L., Brazzell, J. L., Barron, M., Aho, J., Blanco, E., Powell, C., Johnson, J. & Wigle, D. A., Jun 2022, In: Journal of Thoracic Disease. 14, 6, p. 1830-1839 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Polyurethanes 100%
  • Swine 63%
  • Animals 40%
  • Stents 22%
  • Diet 18%

• Trastuzumab with trimodality treatment for oesophageal adenocarcinoma with HER2 overexpression (NRG Oncology/RTOG 1010): a multicentre, randomised, phase 3 trial

  Safran, H. P., Winter, K., Ilson, D. H., Wigle, D., DiPetrillo, T., Haddock, M. G., Hong, T. S., Leichman, L. P., Rajdev, L., Resnick, M., Kachnic, L. A., Seaward, S., Mamon, H., Diaz Pardo, D. A., Anderson, C. M., Shen, X., Sharma, A. K., Katz, A. W., Salo, J., Leonard, K. L., & 2 othersMoughan, J. & Crane, C. H., Feb 2022, In: The Lancet Oncology. 23, 2, p. 259-269 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Trastuzumab 100%
  • Chemoradiotherapy 89%
  • Adenocarcinoma 65%
  • Disease-Free Survival 16%
  • Therapeutics 13%
• 2021

  Ablative radiotherapy for ultracentral lung cancers: Dosimetric, geometric, and volumetric predictors of outcomes and toxicity

  Breen, W. G., Jeans, E. B., Gergelis, K. R., Garces, Y. I., Park, S. S., Merrell, K. W., Peikert, T. D., Mansfield, A. S., Wigle, D. A., Harmsen, W. S., Ellerbusch, D. C., Olivier, K. R., John Lucido, J. & Owen, D., May 2021, In: Radiotherapy and Oncology. 158, p. 246-252 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Tumor Burden 100%
  • Lung Neoplasms 83%
  • Radiotherapy 72%
  • Pericardium 46%
  • Lung 45%

• A Comparison of Negative Pressure and Conventional Therapy in Infected Open Chest Wounds

  Thomas, M., Makey, I. A., Buchanan, M. A., Heckman, M. G., White, L. J., Lechtenberg, B. J., Wigle, D., Shen, K. R. & Blackmon, S. H., Nov 2021, In: Surgical Infections. 22, 9, p. 955-961 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Negative-Pressure Wound Therapy 100%
  • Thorax 62%
  • Pressure 58%
  • Wounds and Injuries 43%
  • Length of Stay 18%

• Autologous blood patch pleurodesis for prolonged postoperative air leaks

  Hasan, I. S., Allen, M. S., Cassivi, S. D., Harmsen, W. S., Mahajan, N., Nichols, F. C., Reisenauer, J., Shen, R. K., Wigle, D. A. & Blackmon, S. H., Jun 2021, In: Journal of Thoracic Disease. 13, 6, p. 3347-3358 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pleurodesis 100%
  • Air 57%
  • Empyema 9%
  • Reoperation 7%
  • Lung 6%

• Contemporary Practice Patterns of Lung Volume Reduction Surgery in the United States

  Abdelsattar, Z. M., Allen, M., Blackmon, S., Cassivi, S., Mandrekar, J., Nichols, F., Reisenauer, J., Wigle, D. & Shen, K. R., Sep 2021, In: Annals of Thoracic Surgery. 112, 3, p. 952-960 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Pneumonectomy 100%
  • Chronic Obstructive Pulmonary Disease 27%
  • Odds Ratio 27%
  • Thorax 21%
  • Mortality 21%

• First-in-Human Segmental Esophageal Reconstruction Using a Bioengineered Mesenchymal Stromal Cell–Seeded Implant

  Aho, J. M., La Francesca, S., Olson, S. D., Triolo, F., Bouchard, J., Mondano, L., Sundaram, S., Roffidal, C., Cox, C. S., Wong Kee Song, L. M., Said, S. M., Fodor, W. & Wigle, D. A., Sep 2021, In: JTO Clinical and Research Reports. 2, 9, 100216.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transplants 100%
  • Regeneration 89%
  • Esophagus 74%
  • Investigational Drugs 74%
  • Mesenchymal Stem Cells 71%

• Heterogeneity of PD-L1 expression between invasive and lepidic components of lung adenocarcinomas

  Hazim, A., Majithia, N., Murphy, S. J., Wigle, D., Aubry, M. C. & Mansfield, A. S., Sep 2021, In: Cancer Immunology, Immunotherapy. 70, 9, p. 2651-2656 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Adenocarcinoma of Lung 100%
  • Neoplasms 30%
  • Immunotherapy 13%
  • Patient Selection 13%
  • Clone Cells 12%