General Internal Medicine

Research Output

2018

Senolytics improve physical function and increase lifespan in old age

Xu, M., Pirtskhalava, T., Farr, J., Weigand, B. M., Palmer, A. K., Weivoda, M., Inman, C. L., Ogrodnik, M. B., Hachfeld, C. M., Fraser, D. G., Onken, J. L., Johnson, K. O., Verzosa, G. C., Langhi, L. G. P., Weigl, M., Giorgadze, N., LeBrasseur, N. K., Miller, J. D., Jurk, D., Singh, R. J. & 13 others, Allison, D. B., Ejima, K., Hubbard, G. B., Ikeno, Y., Cubro, H., Garovic, V. D., Hou, X., Weroha, S. J., Robbins, P. D., Niedernhofer, L. J., Khosla, S., Tchkonia, T. & Kirkland, J. L., Aug 1 2018, In : Nature Medicine. 24, 8, p. 1246-1256 11 p.

Research output: Contribution to journalArticle

220 Scopus citations

Sexual Health in Women

Kapoor, E., Kling, J. M., Kingsberg, S. A. & Faubion, S. S., Sep 1 2018, In : Journal of Women's Health. 27, 9, p. 1082-1085 4 p.

Research output: Contribution to journalArticle

SLCO1B1 genetic variation and hormone therapy in menopausal women

Moyer, A., De Andrade, M., Faubion, S. S., Kapoor, E., Dudenkov, T., Weinshilboum, R. M. & Miller, V. M., Aug 1 2018, In : Menopause (New York, N.Y.). 25, 8, p. 877-882 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Stroma modifies relationships between risk factor exposure and age-related epithelial involution in benign breast

Chollet-Hinton, L., Puvanesarajah, S., Sandhu, R., Kirk, E. L., Midkiff, B. R., Ghosh, K., Brandt, K. R., Scott, C. G., Gierach, G. L., Sherman, M. E., Vachon, C. M. & Troester, M. A., Feb 20 2018, (Accepted/In press) In : Modern Pathology. p. 1-12 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Supporting self-regulation in simulation-based education: a randomized experiment of practice schedules and goals

Cook, D. A., Aljamal, Y., Pankratz, V. S., Sedlack, R. E., Farley, D. R. & Brydges, R., Jan 1 2018, (Accepted/In press) In : Advances in Health Sciences Education.

Research output: Contribution to journalArticle

2 Scopus citations

Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2−/−) mice

Moncsek, A., Al-Suraih, M. S., Trussoni, C. E., O'Hara, S. P., Splinter, P. L., Zuber, C., Patsenker, E., Valli, P. V., Fingas, C. D., Weber, A., Zhu, Y., Tchkonia, T., Kirkland, J. L., Gores, G. J., Müllhaupt, B., La Russo, N. F. & Mertens, J. C., Jan 1 2018, In : Hepatology. 67, 1, p. 247-259 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

The comparative effectiveness of decision aids in diverse populations with early stage prostate cancer: A study protocol for a cluster-randomized controlled trial in the NCI Community Oncology Research Program (NCORP), Alliance A191402CD

Pacyna, J. E., Kim, S., Yost, K. J., Sedlacek, H., Petereit, D., Kaur, J. S., Rapkin, B., Grubb, R., Paskett, E., Chang, G. J., Sloan, J. A., Basch, E., Major, B., Novotny, P., Taylor, J., Buckner, J. C., Parsons, J. K., Morris, M. & Tilburt, J. C., Aug 6 2018, In : BMC Cancer. 18, 1, 788.

Research output: Contribution to journalArticle

The Ethnopharmacologic Contribution to Bioprospecting Natural Products

Buenz, E. J., Verpoorte, R. & Bauer, B. A., Jan 6 2018, In : Annual Review of Pharmacology and Toxicology. 58, p. 509-530 22 p.

Research output: Contribution to journalReview article

11 Scopus citations

The Experience of Hospital Death: Assessing the Quality of Care at an Academic Medical Center

Carey, E., Dose, A. M., Humeniuk, K. M., Kuan, Y. C., Hicks, A. D., Ottenberg, A. L., Tilburt, J. C. & Koenig, B., Feb 1 2018, In : American Journal of Hospice and Palliative Medicine. 35, 2, p. 189-197 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

The Impact of Social Media on Negative Online Physician Reviews: an Observational Study in a Large, Academic, Multispecialty Practice

Widmer, R. J., Shepard, M., Aase, L. A., Wald, J. T., Pruthi, S. & Timimi, F. K., Jan 1 2018, (Accepted/In press) In : Journal of General Internal Medicine.

Research output: Contribution to journalArticle

1 Scopus citations

The International Society for the Study of Women's Sexual Health Process of Care for Management of Hypoactive Sexual Desire Disorder in Women

Clayton, A. H., Goldstein, I., Kim, N. N., Althof, S. E., Faubion, S. S., Faught, B. M., Parish, S. J., Simon, J. A., Vignozzi, L., Christiansen, K., Davis, S. R., Freedman, M. A., Kingsberg, S. A., Kirana, P. S., Larkin, L., McCabe, M. & Sadovsky, R., Jan 1 2018, (Accepted/In press) In : Mayo Clinic Proceedings.

Research output: Contribution to journalArticle

27 Scopus citations

The murine dialysis fistula model exhibits a senescence phenotype: pathobiological mechanisms and therapeutic potential

Nath, K. A., O'Brien, D. R., Croatt, A. J., Grande, J. P., Ackerman, A. W., Nath, M. C., Yamada, S., Terzic, A., Tchkonia, T., Kirkland, J. L. & Katusic, Z. S., Nov 1 2018, In : American journal of physiology. Renal physiology. 315, 5, p. F1493-F1499

Research output: Contribution to journalArticle

5 Scopus citations

The Return of Actionable Variants Empirical (RAVE) Study, a Mayo Clinic Genomic Medicine Implementation Study: Design and Initial Results

Kullo, I. J., Olson, J. E., Fan, X., Jose, M., Safarova, M., Radecki Breitkopf, C., Winkler, E., Kochan, D. C., Snipes, S., Pacyna, J. E., Carney, M., Chute, C. G., Gupta, J., Jose, S., Venner, E., Murugan, M., Jiang, Y., Zordok, M., Farwati, M., Philogene, M. & 7 others, Smith, E., Shaibi, G. Q., Caraballo, P., Freimuth, R., Lindor, N. M., Sharp, R. R. & Thibodeau, S. N., Nov 1 2018, In : Mayo Clinic Proceedings. 93, 11, p. 1600-1610 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

The value proposition of simulation-based education

Cook, D. A., Andersen, D. K., Combes, J. R., Feldman, D. L. & Sachdeva, A. K., Jan 1 2018, (Accepted/In press) In : Surgery (United States).

Research output: Contribution to journalArticle

12 Scopus citations

Tobacco Dependence Treatment Grants: A Collaborative Approach to the Implementation of WHO Tobacco Control Initiatives

Nolan, M. B., Kemper, K. E., Glynn, T. J., Hurt, R. D. & Hays, J. T., Jan 1 2018, In : Journal of Environmental and Public Health. 2018, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

To Pull or Not to Pull: Salvaging Central Line Catheters in Home Parenteral Nutrition

Bonnes, S. L., Mundi, M. S., Hurt, R. T. & Salonen, B. R., Dec 1 2018, In : Current Nutrition Reports. 7, 4, p. 324-328 5 p.

Research output: Contribution to journalReview article

Transcriptomic signatures of cellular and humoral immune responses in older adults after seasonal influenza vaccination identified by data-driven clustering

Voigt, E. A., Grill, D. E., Zimmermann, M. T., Simon, W. L., Ovsyannikova, I. G., Kennedy, R. B. & Poland, G. A., Dec 1 2018, In : Scientific Reports. 8, 1, 739.

Research output: Contribution to journalArticle

9 Scopus citations

Ultrasound guided percutaneous common carotid artery access in piglets for intracoronary stem cell infusion

for the Wanek Program Preclinical Pipeline, Feb 1 2018, In : Laboratory Animals. 52, 1, p. 88-92 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Update in Outpatient General Internal Medicine: Practice-Changing Evidence Published in 2017

Wieland, M. L., Szostek, J. H., Wingo, M. T., Post, J. A. & Mauck, K. F., Jan 1 2018, (Accepted/In press) In : American Journal of Medicine.

Research output: Contribution to journalArticle

Vamorolone treatment improves skeletal muscle outcome in a critical illness myopathy rat model

Akkad, H., Cacciani, N., Llano-Diez, M., Corpeno Kalamgi, R., Tchkonia, T., Kirkland, J. L. & Larsson, L., Jan 1 2018, (Accepted/In press) In : Acta Physiologica.

Research output: Contribution to journalArticle

2 Scopus citations

Varenicline for tobacco-dependence treatment in alcohol-dependent smokers: A randomized controlled trial

Hurt, R. T., Ebbert, J. O., Croghan, I. T., Schroeder, D. R., Hurt, R. D. & Hays, J. T., Mar 1 2018, In : Drug and Alcohol Dependence. 184, p. 12-17 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Vasomotor symptoms in women over 60: Results from the Data Registry on Experiences of Aging, Menopause, and Sexuality (DREAMS)

David, P. S., Kling, J. M., Vegunta, S., Faubion, S. S., Kapoor, E., Mara, K. C., Schroeder, D. R., Frohmader Hilsaca, K. & Kuhle, C. L., Jan 1 2018, In : Menopause. 25, 10, p. 1105-1109 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Voluntarily stopping eating and drinking among patients with serious advanced illness-a label in search of a problem?

Mueller, P., Strand, J. J. & Tilburt, J. C., May 1 2018, In : JAMA Internal Medicine. 178, 5, p. 726-727 2 p.

Research output: Contribution to journalLetter

Weight Regain After Bariatric Surgery: Prevalence, Etiology, and Treatment

Velapati, S. R., Shah, M., Kuchkuntla, A. R., Abu-Dayyeh, B., Grothe, K., Hurt, R. T. & Mundi, M. S., Dec 1 2018, In : Current Nutrition Reports. 7, 4, p. 329-334 6 p.

Research output: Contribution to journalReview article

15 Scopus citations
2017

17α-estradiol alleviates age-related metabolic and inflammatory dysfunction in male mice without inducing feminization

Stout, M. B., Steyn, F. J., Jurczak, M. J., Camporez, J. P. G., Zhu, Y., Hawse, J. R., Jurk, D., Palmer, A. K., Xu, M., Pirtskhalava, T., Evans, G. L., De Souza Santos, R., Frank, A. P., White, T. A., Monroe, D. G., Singh, R. J., Casaclang-Verzosa, G., Miller, J. D., Clegg, D. J., LeBrasseur, N. K. & 4 others, Von Zglinicki, T., Shulman, G. I., Tchkonia, T. & Kirkland, J. L., 2017, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 1, p. 3-15 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

58-Year-Old Woman With Diarrhea, Weakness, and Memory Loss

Challener, D. W., Saleh, O. A. & Whitaker, J. A., 2017, (Accepted/In press) In : Mayo Clinic Proceedings.

Research output: Contribution to journalArticle

65-Year-Old Man With Weight Loss and Progressive Acral Necrosis

Ho, T. P., Strati, P. & Chon, T. Y., Apr 1 2017, In : Mayo Clinic Proceedings. 92, 4, p. 605-608 4 p.

Research output: Contribution to journalShort survey

73-Year-Old Asymptomatic Woman With Anemia

Jansson-Knodell, C. & Collins, C. S., Jun 1 2017, In : Mayo Clinic proceedings. 92, 6, p. e89-e93

Research output: Contribution to journalShort survey

A Conceptual Framework for Understanding Unintended Prolonged Opioid Use

Hooten, W. M., Brummett, C. M., Sullivan, M. D., Goesling, J., Tilburt, J. C., Merlin, J. S., St. Sauver, J., Wasan, A. D., Clauw, D. J. & Warner, D. O., Dec 1 2017, In : Mayo Clinic Proceedings. 92, 12, p. 1822-1830 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Acupuncture for benign prostatic hyperplasia: A systematic review and meta-analysis

Zhang, W., Ma, L., Bauer, B. A., Liu, Z. & Lu, Y., Apr 1 2017, In : PLoS One. 12, 4, e0174586.

Research output: Contribution to journalReview article

2 Scopus citations

Addressing Palliative Care Clinician Burnout in Organizations: A Workforce Necessity, an Ethical Imperative

Harrison, K. L., Dzeng, E., Ritchie, C. S., Shanafelt, T. D., Kamal, A. H., Bull, J. H., Tilburt, J. C. & Swetz, K. M., 2017, (Accepted/In press) In : Journal of Pain and Symptom Management.

Research output: Contribution to journalArticle

13 Scopus citations

Addressing physician burnout the way forward

Shanafelt, T. D., Dyrbye, L. L. & West, C. P., Mar 7 2017, In : JAMA - Journal of the American Medical Association. 317, 9, p. 901-902 2 p.

Research output: Contribution to journalShort survey

120 Scopus citations

Addressing physician burnout - The way forward

Shanafelt, T. D., Dyrbye, L. L. & West, C. P., Aug 1 2017, In : Obstetrical and Gynecological Survey. 72, 8, p. 462-463 2 p.

Research output: Contribution to journalComment/debate

Adverse childhood or adult experiences and risk of bilateral oophorectomy: A population-based case-control study

Rocca, L. G., Smith, C. Y., Grossardt, B. R., Faubion, S. S., Shuster, L. T., Stewart, E. A. & Rocca, W. A., May 1 2017, In : BMJ Open. 7, 5, e016045.

Research output: Contribution to journalArticle

9 Scopus citations

A large population-based association study between HLA and KIR genotypes and measles vaccine antibody responses

Ovsyannikova, I. G., Schaid, D. J., Larrabee, B. R., Haralambieva, I. H., Kennedy, R. B. & Poland, G. A., Feb 1 2017, In : PLoS One. 12, 2, e0171261.

Research output: Contribution to journalArticle

8 Scopus citations

An integrated digital/clinical approach to smoking cessation in lung cancer screening: Study protocol for a randomized controlled trial

Graham, A. L., Burke, M. V., Jacobs, M. A., Cha, S., Croghan, I. T., Schroeder, D. R., Moriarty, J. P., Borah, B. J., Rasmussen, D. F., Brookover, M. J., Suesse, D. B., Midthun, D. E. & Hays, J. T., Nov 28 2017, In : Trials. 18, 1, 568.

Research output: Contribution to journalArticle

4 Scopus citations

Aortic hemodynamics and white matter hyperintensities in normotensive postmenopausal women

Barnes, J. N., Harvey, R. E., Zuk, S. M., Lundt, E. S., Lesnick, T. G., Gunter, J. L., Senjem, M. L., Shuster, L. T., Miller, V. M., Jack, C. R. J., Joyner, M. J. & Kantarci, K. M., Apr 7 2017, (Accepted/In press) In : Journal of Neurology. p. 1-8 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

A prospective double blind randomized controlled study on the use of ethanol locks in HPN patients

Salonen, B. R., Bonnes, S. L., Vallumsetla, N., Varayil, J. E., Mundi, M. S. & Hurt, R. T., Jan 17 2017, (Accepted/In press) In : Clinical Nutrition.

Research output: Contribution to journalArticle

9 Scopus citations

A prospective observational study assessing the feasibility of measuring blood lead levels in New Zealand hunters eating meat harvested with lead projectiles

Buenz, E. J., Parry, G. J., Bauer, B. A., Matheny, L. M. & Breukel, K., Mar 1 2017, In : Contemporary Clinical Trials Communications. 5, p. 137-143 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Aromatase expression in atypical ductal hyperplasia in women

Santen, R. J., Radisky, D. C., Degnim, A. C., Frost, M. H., Vachon, C. M., Ghosh, K., Guestini, F., McNamara, K. M. & Sasano, H., Mar 23 2017, (Accepted/In press) In : Breast Cancer Research and Treatment. p. 1-7 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Association between mammographic breast density and histologic features of benign breast disease

Ghosh, K., Vierkant, R. A., Frank, R. D., Winham, S. J., Visscher, D. W., Pankratz, V. S., Scott, C. G., Brandt, K. R., Sherman, M. E., Radisky, D. C., Frost, M. H., Hartmann, L. C., Degnim, A. C. & Vachon, C. M., Dec 19 2017, In : Breast Cancer Research. 19, 1, 134.

Research output: Contribution to journalArticle

10 Scopus citations

Association of 3 different antihypertensive medications with hip and pelvic fracture risk in older adults secondary analysis of a randomized clinical trial

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Collaborative Research Group, Jan 1 2017, In : JAMA Internal Medicine. 177, 1, p. 67-76 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Associations between teaching effectiveness and participant self-reflection in continuing medical education

Ratelle, J. T., Bonnes, S. L., Wang, A. T., Mahapatra, S., Schleck, C. D., Mandrekar, J., Mauck, K. F., Beckman, T. J. & Wittich, C. M., Mar 16 2017, (Accepted/In press) In : Medical Teacher. p. 1-7 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Automated T-wave analysis can differentiate acquired QT prolongation from congenital long QT syndrome

Sugrue, A., Noseworthy, P., Kremen, V., Bos, J. M., Qiang, B., Rohatgi, R. K., Sapir, Y., Attia, Z. I., Brady, P., Caraballo, P., Asirvatham, S. J., Friedman, P. A. & Ackerman, M. J., 2017, (Accepted/In press) In : Annals of Noninvasive Electrocardiology.

Research output: Contribution to journalArticle

2 Scopus citations
22 Scopus citations

Bilateral Oophorectomy and Accelerated Aging: Cause or Effect?

Rocca, W. A., Gazzuola Rocca, L., Smith, C. Y., Grossardt, B. R., Faubion, S. S., Shuster, L. T., Kirkland, J. L., Stewart, E. A. & Miller, V. M., Sep 1 2017, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 72, 9, p. 1213-1217 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Biology of premature ageing in survivors of cancer

Cupit-Link, M. C., Kirkland, J. L., Ness, K. K., Armstrong, G. T., Tchkonia, T., LeBrasseur, N. K., Armenian, S. H., Ruddy, K. J. & Hashmi, S. K., Dec 1 2017, In : ESMO Open. 2, 5, e000250.

Research output: Contribution to journalReview article

27 Scopus citations

Breast cysts rapidly enlarging with replacement of breast parenchyma and asymmetry

Al-Hilli, Z., Javed, A., Boughey, J. C., Lemaine, V., Visscher, D. W. & Pruthi, S., 2017, (Accepted/In press) In : Breast Journal.

Research output: Contribution to journalArticle

Care of the dialysis patient: Primary provider involvement and resource utilization patterns - A cohort study

Thorsteinsdottir, B. B., Ramar, P., Hickson, L., Reinalda, M. S., Albright, R. C., Tilburt, J. C., Williams, A. W., Takahashi, P. Y., Jeffery, M. M. & Shah, N. D., Oct 25 2017, In : BMC Nephrology. 18, 1, 322.

Research output: Contribution to journalArticle

1 Scopus citations

Caring for the lesbian patient at midlife and beyond

Rullo, J. E. & Faubion, S. S., Jul 10 2017, (Accepted/In press) In : Menopause.

Research output: Contribution to journalArticle

1 Scopus citations