Gastroenterology and Hepatology

Convolutional Neural Networks for Medical Image Analysis: Full Training or Fine Tuning?

Tajbakhsh, N., Shin, J. Y., Gurudu, S. R., Hurst, R. T., Kendall, C. B., Gotway, M. & Liang, J., May 1 2016, In : IEEE Transactions on Medical Imaging. 35, 5, p. 1299-1312 14 p., 7426826.

Research output: Contribution to journal › Article

Gastroenterology

Diagnostic Imaging

Cardiology

Radiology

Image analysis

125 Citations (Scopus)

Coping Strategies and Interpersonal Support in Patients With Irritable Bowel Syndrome and Inflammatory Bowel Disease

Jones, M. P., Wessinger, S. & Crowell, M. D., Apr 2006, In : Clinical Gastroenterology and Hepatology. 4, 4, p. 474-481 8 p.

Research output: Contribution to journal › Article

Irritable Bowel Syndrome

Inflammatory Bowel Diseases

Quality of Life

Social Support

Affective Symptoms

15 Citations (Scopus)

Copper deficiency myeloneuropathy due to occult celiac disease

Goodman, B. P., Mistry, D. H., Pasha, S. F. & Bosch, P. E., Nov 2009, In : Neurologist. 15, 6, p. 355-356 2 p.

Research output: Contribution to journal › Article

Celiac Disease

Copper

Ataxia

Gait

Gliadin

10 Citations (Scopus)

Correlation of two capsule endoscopy scoring systems with fecal calprotectin: Does it really matter?

Gurudu, S. R. & Leighton, J. A., Apr 2012, In : Digestive Diseases and Sciences. 57, 4, p. 827-829 3 p.

Research output: Contribution to journal › Article

Leukocyte L1 Antigen Complex

Capsule Endoscopy

Feces

Crohn Disease

Small Intestine

44 Citations (Scopus)

Corticosteroid treatment for autoimmune pancreatitis

Pannala, R. & Chari, S. T., Nov 2009, In : Gut. 58, 11, p. 1438-1439 2 p.

Research output: Contribution to journal › Article

Pancreatitis

Autoimmune Diseases

Adrenal Cortex Hormones

75 Citations (Scopus)

C-reactive protein and high-sensitivity C-reactive protein: An update for clinicians

Windgassen, E. B., Funtowicz, L., Lunsford, T. N., Harris, L. A. & Mulvagh, S. L., Jan 2011, In : Postgraduate Medicine. 123, 1, p. 114-119 6 p.

Research output: Contribution to journal › Article

C-Reactive Protein

Hydroxymethylglutaryl-CoA Reductase Inhibitors

Cardiovascular Diseases

Risk Management

Rheumatology

161 Citations (Scopus)

Critical contributions of amino-terminal extracellular domains in agonist binding and activation of secretin and vasoactive intestinal polypeptide receptors: Studies of chimeric receptors

Holtmann, M. H., Hadac, E. M. & Miller, L. J., Jun 16 1995, In : Journal of Biological Chemistry. 270, 24, p. 14394-14398 5 p.

Research output: Contribution to journal › Article

Secretin

Vasoactive Intestinal Peptide

Chemical activation

Inhibitory Concentration 50

COS Cells

235 Citations (Scopus)

Crohn disease of the small bowel: Preliminary comparison among CT enterography, capsule endoscopy, small-bowel follow-through, and ileoscopy

Hara, A. K., Leighton, J. A., Heigh, R. I., Sharma, V. K., Silva, A. C., De Petris, G., Hentz, J. G. & Fleischer, D. E., Jan 2006, In : Radiology. 238, 1, p. 128-134 7 p.

Research output: Contribution to journal › Article

Capsule Endoscopy

Crohn Disease

Research Ethics Committees

Diagnostic Imaging

Colonoscopy

3 Citations (Scopus)

Cronkhite-Canada syndrome diagnosis in the absence of gastrointestinal polyps: A case report

De Petris, G., Chen, L., Pasha, S. F. & Ruff, K. C., Dec 2013, In : International Journal of Surgical Pathology. 21, 6, p. 627-631 5 p.

Research output: Contribution to journal › Article

Intestinal Polyposis

Polyps

Atrophy

Edema

Mucous Membrane

20 Citations (Scopus)

Cross-chimeric analysis of selectivity of secretin and VPAC₁ receptor activation

Park, C. G., Ganguli, S. C., Pinon, D. I., Hadac, E. M. & Miller, L. J., 2000, In : Journal of Pharmacology and Experimental Therapeutics. 295, 2, p. 682-688 7 p.

Research output: Contribution to journal › Article

Receptors, Vasoactive Intestinal Polypeptide, Type I

Secretin

Vasoactive Intestinal Peptide

Ligands

G-Protein-Coupled Receptors

38 Citations (Scopus)

Cryo-EM structure of the active, G_s-protein complexed, human CGRP receptor

Liang, Y. L., Khoshouei, M., Deganutti, G., Glukhova, A., Koole, C., Peat, T. S., Radjainia, M., Plitzko, J. M., Baumeister, W., Miller, L. J., Hay, D. L., Christopoulos, A., Reynolds, C. A., Wootten, D. & Sexton, P. M., Sep 27 2018, In : Nature. 561, 7724, p. 492-497 6 p.

Research output: Contribution to journal › Article

Calcitonin Receptor-Like Protein

Calcitonin Gene-Related Peptide Receptors

Receptor Activity-Modifying Protein 1

Calcitonin Gene-Related Peptide

G-Protein-Coupled Receptors

c-Src regulates cargo transit via the Golgi in pancreatic acinar cells

Kostenko, S., Heu, C. C., Yaron, J. R., Singh, G., de Oliveira, C., Muller, W. J. & Singh, V. P., Dec 1 2018, In : Scientific Reports. 8, 1, 11903.

Research output: Contribution to journal › Article

Acinar Cells

Secretory Vesicles

Amylases

Pancreatitis

Staining and Labeling

23 Citations (Scopus)

CT colonography with intravenous contrast material: Varied appearances of colorectal carcinoma

Silva, A. C., Hara, A. K., Leighton, J. A. & Heppell, J. P., Sep 2005, In : Radiographics. 25, 5, p. 1321-1334 14 p.

Research output: Contribution to journal › Article

Computed Tomographic Colonography

Contrast Media

Colorectal Neoplasms

Neoplasm Staging

Diverticulum

4 Citations (Scopus)

Culture behavior of healthy bovine gallbladder muscularis smooth muscle cells

Sas, D. & Miller, L. J., 1988, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 255, 5

Research output: Contribution to journal › Article

Gallbladder

Smooth Muscle Myocytes

Intermediate Filament Proteins

Desmin

Fibroblasts

1 Citation (Scopus)

Culture of human neoplastic gastrointestinal smooth muscle cells

Sas, D. F., Lundy, J. K. & Miller, L. J., 1989, In : In Vitro Cellular and Developmental Biology - Animal. 25, 8, p. 730-736 7 p.

Research output: Contribution to journal › Article

11 Citations (Scopus)

Curcumin in hepatobiliary disease: Pharmacotherapeutic properties and emerging potential clinical applications

Hu, R. W., Carey, E. J., Lindor, K. D. & Tabibian, J. H., Nov 1 2017, In : Annals of Hepatology. 16, 6, p. 835-841 7 p.

Research output: Contribution to journal › Article

Curcumin

Curcuma

Sclerosing Cholangitis

Rhizome

Cholangiocarcinoma

16 Citations (Scopus)

Current concepts and treatment options in eosinophilic esophagitis

Pasha, S. F., Sharma, V. K. & Crowell, M. D., Nov 2006, In : Current Opinion in Investigational Drugs. 7, 11, p. 992-996 5 p.

Research output: Contribution to journal › Article

Eosinophilic Esophagitis

Esophagus

Interleukin-5

Food

Allergens

2 Citations (Scopus)

Current mechanisms of action in treatment of chronic constipation and irritable bowel syndrome

Harris, L. A., Apr 2006, In : Advanced Studies in Medicine. 6, 4 A

Research output: Contribution to journal › Article

Irritable Bowel Syndrome

Constipation

Laxatives

Therapeutics

Life Style

27 Citations (Scopus)

Current pharmacotherapy for cholestatic liver disease

Carey, E. J. & Lindor, K. D., Dec 2012, In : Expert Opinion on Pharmacotherapy. 13, 17, p. 2473-2484 12 p.

Research output: Contribution to journal › Article

Liver Diseases

Ursodeoxycholic Acid

Biliary Liver Cirrhosis

Drug Therapy

Sclerosing Cholangitis

Current place of capsule endoscopy in Crohn's disease

Islam, R. S., Patel, N. C. & Leighton, J. A., 2012, In : Inflammatory Bowel Disease Monitor. 12, 4, p. 143-148 6 p.

Research output: Contribution to journal › Article

Capsule Endoscopy

Crohn Disease

Ileum

Mucous Membrane

Inflammation

23 Citations (Scopus)

Cyclophosphamide-induced hepatotoxicity in a patient with Wegener's granulomatosis

Snyder, L. S., Heigh, R. I. & Anderson, M. L., 1993, In : Mayo Clinic Proceedings. 68, 12, p. 1203-1204 2 p.

Research output: Contribution to journal › Article

Granulomatosis with Polyangiitis

Cyclophosphamide

Liver Function Tests

Therapeutics

Vasculitis

2 Citations (Scopus)

Cyclosporine, or cyclosporine not, for severe ulcerative colitis.

Leighton, J. A., Nov 2001, In : Inflammatory Bowel Diseases. 7, 4, p. 350-352 3 p.

Research output: Contribution to journal › Article

Severity of Illness Index

Immunosuppressive Agents

Ulcerative Colitis

Cyclosporine

Clinical Trials

46 Citations (Scopus)

Cyclosporine-associated central nervous system toxicity

Bhatt, B. D., Meriano, F. V., Buchwald, D., Tollemar, J., Ringden, O., Ericzon, B. G., Tyden, G., De Groen, P. C., Aksamit, A. J., Rakela, J. & Krom, R. A. F., 1988, In : New England Journal of Medicine. 318, 12, p. 788-789 2 p.

Research output: Contribution to journal › Article

Cyclosporins

Cyclosporine

Liver Diseases

Central Nervous System

Brain

117 Citations (Scopus)

Cytomegalovirus hepatitis in liver transplantation: Prospective analysis of 93 consecutive orthotopic liver transplantations

Paya, C. V., Hermans, P. E., Wiesner, R. H., Ludwig, J., Smith, T. F., Rakela, J. & Krom, R. A. F., 1989, In : Journal of Infectious Diseases. 160, 5, p. 752-758 7 p.

Research output: Contribution to journal › Article

Cytomegalovirus

Liver Transplantation

Hepatitis

Ganciclovir

Liver

7 Citations (Scopus)

Deep enteroscopy in patients with left ventricular assist devices: Practical and technical considerations

Decker, G. A., Miller, E. D., Pasha, S. F., Harrison, M. E. & Leighton, J. A., 2010, In : Endoscopy. 42, SUPPL. 2

Research output: Contribution to journal › Article

9 Citations (Scopus)

Delayed hemolysis resulting from anti-A₁ after liver transplantation

Brecher, M. E., Moore, S. B., Reisner, R. K., Rakela, J. & Krom, R. A. F., 1989, In : American Journal of Clinical Pathology. 91, 2, p. 232-235 4 p.

Research output: Contribution to journal › Article

Hemolysis

varespladib methyl

Liver Transplantation

Transplantation

Coombs Test

81 Citations (Scopus)

Demonstration of a direct interaction between residue 22 in the carboxyl-terminal half of secretin and the amino-terminal tail of the secretin receptor using photoaffinity labeling

Dong, M., Asmann, Y., Pinon, D. I., Hadac, E. M. & Miller, L. J., Jan 8 1999, In : Journal of Biological Chemistry. 274, 2, p. 903-909 7 p.

Research output: Contribution to journal › Article

Secretin

Labeling

Tail

Demonstrations

Proteolysis

12 Citations (Scopus)

Demonstration of a specific site of covalent labeling of the human motilin receptor using a biologically active photolabile motilin analog

Matsuura, B., Dong, M., Coulie, B., Pinon, D. I. & Miller, L. J., Jun 2005, In : Journal of Pharmacology and Experimental Therapeutics. 313, 3, p. 1101-1108 8 p.

Research output: Contribution to journal › Article

Motilin

Ghrelin Receptor

Cyanogen Bromide

Drug Design

G-Protein-Coupled Receptors

14 Citations (Scopus)

Design and baseline characteristics of participants in a phase III randomized trial of celecoxib and selenium for colorectal adenoma prevention

Thompson, P., Roe, D. J., Fales, L., Buckmeier, J., Wang, F., Hamilton, S. R., Bhattacharyya, A., Green, S., Hsu, C. H., Sherry Chow, H. H., Ahnen, D. J., Boland, C. R., Heigh, R. I., Fay, D. E., Martinez, M. E., Jacobs, E., Ashbeck, E. L., Alberts, D. S. & Lance, P., Dec 2012, In : Cancer Prevention Research. 5, 12, p. 1381-1393 13 p.

Research output: Contribution to journal › Article

Celecoxib

Selenium

Adenoma

Random Allocation

Cyclooxygenase 2 Inhibitors

37 Citations (Scopus)

Design of treatment trials for functional gastrointestinal disorders

Irvine, E. J., Tack, J., Crowell, M. D., Gwee, K. A., Ke, M., Schmulson, M. J., Whitehead, W. E. & Spiegel, B., May 1 2016, In : Gastroenterology. 150, 6, p. 1469-1480e1

Research output: Contribution to journal › Article

Gastrointestinal Diseases

Nocebo Effect

Therapeutics

Placebos

Placebo Effect

12 Citations (Scopus)

Detecting hepatic steatosis using ultrasound-induced thermal strain imaging: An ex vivo animal study

Mahmoud, A. M., Ding, X., Dutta, D., Singh, V. P. & Kim, K., Feb 21 2014, In : Physics in Medicine and Biology. 59, 4, p. 881-895 15 p.

Research output: Contribution to journal › Article

Hot Temperature

Fatty Liver

Liver

Heating

Fats

131 Citations (Scopus)

Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid

Laskus, T., Radkowski, M., Bednarska, A., Wilkinson, J., Adair, D., Nowicki, M., Nikolopoulou, G. B., Vargas, H. E. & Rakela, J., Oct 2002, In : Journal of Virology. 76, 19, p. 10064-10068 5 p.

Research output: Contribution to journal › Article

Hepatitis C virus

cerebrospinal fluid

mononuclear leukocytes

Hepacivirus

Cerebrospinal Fluid

82 Citations (Scopus)

Detection of active hepatitis C virus and hepatitis G virus/GB virus C replication in bone marrow in human subjects

Radkowski, M., Kubicka, J., Kisiel, E., Cianciara, J., Nowicki, M., Rakela, J. & Laskus, T., Jun 15 2000, In : Blood. 95, 12, p. 3986-3989 4 p.

Research output: Contribution to journal › Article

GB virus C

Virus Replication

Viruses

Hepacivirus

Bone

39 Citations (Scopus)

Detection of colorectal serrated polyps by stool DNA testing: comparison with fecal immunochemical testing for occult blood (FIT)

Heigh, R. I., 2014, In : PLoS One. 9, 1, p. e85659

Research output: Contribution to journal › Article

Occult Blood

Polyps

Blood

Screening

DNA

59 Citations (Scopus)

Detection of hepatitis C virus sequences in brain tissue obtained in recurrent hepatitis C after liver transplantation

Vargas, H. E., Laskus, T., Radkowski, M., Wilkinson, J., Balan, V., Douglas, D. D., Harrison, M. E., Mulligan, D. C., Olden, K., Adair, D. & Rakela, J., Nov 1 2002, In : Liver Transplantation. 8, 11, p. 1014-1019 6 p.

Research output: Contribution to journal › Article

Hepatitis C

Hepacivirus

Liver Transplantation

Brain

Virus Replication

40 Citations (Scopus)

Developing valid and reliable health utilities in irritable bowel syndrome: Results from the IBS PROOF cohort

Spiegel, B., Harris, L., Lucak, S., Mayer, E., Naliboff, B., Bolus, R., Esrailian, E., Chey, W. D., Lembo, A., Karsan, H., Tillisch, K., Dulai, G., Talley, J. & Chang, L., Aug 2009, In : American Journal of Gastroenterology. 104, 8, p. 1984-1991 8 p.

Research output: Contribution to journal › Article

Irritable Bowel Syndrome

Health

Cost-Benefit Analysis

Patient Reported Outcome Measures

Quality of Life

19 Citations (Scopus)

Development and initial validation of a measure of perceived stigma in irritable bowel syndrome

Jones, M. P., Keefer, L., Bratten, J., Taft, T. H., Crowell, M. D., Levy, R. & Palsson, O., May 2009, In : Psychology, Health and Medicine. 14, 3, p. 367-374 8 p.

Research output: Contribution to journal › Article

Irritable Bowel Syndrome

Stereotyping

Reproducibility of Results

Social Stigma

Interviews

58 Citations (Scopus)

Development and validation of a method for measuring the glycine and taurine conjugates of bile acids in bile by high-performance liquid chromatography

Tietz, P. S., Thistle, J. L., Miller, L. J. & La Russo, N. F., Dec 7 1984, In : Journal of Chromatography B: Biomedical Sciences and Applications. 336, 1, p. 249-257 9 p.

Research output: Contribution to journal › Article

Taurine

High performance liquid chromatography

Bile Acids and Salts

Bile

Glycine

105 Citations (Scopus)

Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis

Schoepfer, A. M., Straumann, A., Panczak, R., Coslovsky, M., Kuehni, C. E., Maurer, E., Haas, N. A., Romero, Y., Hirano, I., Alexander, J. A., Gonsalves, N., Furuta, G. T., Dellon, E. S., Leung, J., Collins, M. H., Bussmann, C., Netzer, P., Gupta, S. K., Aceves, S. S., Chehade, M. & 46 others, Moawad, F. J., Enders, F. T., Yost, K. J., Taft, T. H., Kern, E., Zwahlen, M., Safroneeva, E., Achem, S. R., Arora, A. S., Alpan, O., Armstrong, D., Attwood, S. E., Butterfield, J. H., Crowell, M. D., De Petris, G., DeVault, K. R., Drouin, E., Enav, B., Fleischer, D. E., Foxx-Orenstein, A., Francis, D. L., Guyatt, G. H., Harris, L. A., Kagalwalla, A. F., Katzka, D. A., Kita, H., Krishna, M., Lee, J. J., Lewis, J. C., Lim, K., Locke, G. R., Murray, J. A., Nguyen, C. C., Orbelo, D. M., Pasha, S. F., Ramirez, F. C., Sheikh, J., Smyrk, T. C., Spergel, J. M., Umar, S. B., Weiler, C. R., Wo, J. M., Woosley, J. T., Wu, T. T., Yan, P. & Yang, G. Y., Dec 1 2014, In : Gastroenterology. 147, 6, p. 1255-1266.e21

Research output: Contribution to journal › Article

Eosinophilic Esophagitis

Deglutition Disorders

Validation Studies

Deglutition

Focus Groups

93 Citations (Scopus)

Development and validation of the Rome IV diagnostic questionnaire for adults

Palsson, O. S., Whitehead, W. E., Van Tilburg, M. A. L., Chang, L., Chey, W., Crowell, M. D., Keefer, L., Lembo, A. J., Parkman, H. P., Rao, S. S. C., Sperber, A., Spiegel, B., Tack, J., Vanner, S., Walker, L. S., Whorwell, P. & Yang, Y., May 1 2016, In : Gastroenterology. 150, 6, p. 1481-1491 11 p.

Research output: Contribution to journal › Article

Constipation

Irritable Bowel Syndrome

Dyspepsia

Gastrointestinal Diseases

Gastroenterology

7 Citations (Scopus)

Development of a biologically active secretin analogue incorporating a radioiodinatable photolabile p-(4-hydroxybenzoyl)phenylalanine in position 10

Dong, M., Pinon, D. I. & Miller, L. J., Nov 15 2002, In : Regulatory Peptides. 109, 1-3, p. 181-187 7 p.

Research output: Contribution to journal › Article

Secretin

Affinity Labels

Ligands

Molecular Models

Molecular modeling

239 Citations (Scopus)

Development of a capsule endoscopy scoring index for small bowel mucosal inflammatory change

Gralnek, I. M., Defranchis, R., Seidman, E., Leighton, J. A., Legnani, P. & Lewis, B. S., Jan 2008, In : Alimentary Pharmacology and Therapeutics. 27, 2, p. 146-154 9 p.

Research output: Contribution to journal › Article

Capsule Endoscopy

Ulcer

Edema

Pathologic Constriction

Language

7 Citations (Scopus)

Development of a highly selective allosteric antagonist radioligand for the type 1 cholecystokinin receptor and elucidation of its molecular basis of binding

Dong, M., Vattelana, A. M., Lam, P. C. H., Orry, A. J., Abagyan, R., Christopoulos, A., Sexton, P. M., Haines, D. R. & Miller, L. J., Jan 1 2015, In : Molecular Pharmacology. 87, 1, p. 130-140 11 p.

Research output: Contribution to journal › Article

Cholecystokinin Receptors

Cholecystokinin B Receptor

Molecular Models

Drug Design

Propionates

3 Citations (Scopus)

Development of a transmucosal technique for erythromycin delivery to treat gastroparesis

Mclemore, R., Lunt, B., Salameh, S., Dibaise, J. K., Crowell, M. D. & Vernon, B. L., Jun 2010, In : Journal of Pharmaceutical Sciences. 99, 6, p. 2905-2913 9 p.

Research output: Contribution to journal › Article

Gastroparesis

Erythromycin

Solubility

Gels

Gastrointestinal Agents

15 Citations (Scopus)

Development of macro-aspartate aminotransferase in a patient undergoing specific allergen injection immunotherapy

Triester, S. L. & Douglas, D. D., Jan 2005, In : American Journal of Gastroenterology. 100, 1, p. 243-245 3 p.

Research output: Contribution to journal › Article

Immunologic Desensitization

Aspartate Aminotransferases

Injections

Molecular Mimicry

Cross Reactions

20 Citations (Scopus)

Development of magnetic beads for rapid and efficient metal-chelate affinity purifications

Ji, Z., Pinon, D. I. & Miller, L. J., Sep 5 1996, In : Analytical Biochemistry. 240, 2, p. 197-201 5 p.

Research output: Contribution to journal › Article

Purification

Resins

Metals

Nitrilotriacetic Acid

Nickel

14 Citations (Scopus)

Development of quality measures for the care of patients withgastroesophageal reflux disease

Yadlapati, R., Gawron, A. J., Bilimoria, K., Keswani, R. N., Dunbar, K. B., Kahrilas, P. J., Katz, P., Richter, J., Schnoll-Sussman, F., Soper, N., Vela, M. F. & Pandolfino, J. E., May 1 2015, In : Clinical Gastroenterology and Hepatology. 13, 5, p. 874-883 10 p.

Research output: Contribution to journal › Article

Quality of Health Care

Gastroesophageal Reflux

Los Angeles

Guidelines

Esophageal Stenosis

1 Citation (Scopus)

Devices and methods to improve colonoscopy completion (with videos)

ASGE Technology Committee, Mar 1 2018, In : Gastrointestinal Endoscopy. 87, 3, p. 688-694.e2

Research output: Contribution to journal › Article

Colonoscopy

Equipment and Supplies

13 Citations (Scopus)

Devices and techniques for ERCP in the surgically altered GI tract

Enestvedt, B. K., Kothari, S., Pannala, R., Yang, J., Fujii-Lau, L. L., Hwang, J. H., Konda, V., Manfredi, M., Maple, J. T., Murad, F. M., Woods, K. L. & Banerjee, S., Mar 4 2016, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journal › Article

1 Citation (Scopus)

Devices for endoscopic hemostasis of nonvariceal GI bleeding (with videos)

ASGE Technology Committee Chair & ASGE Technology Committee, Jul 1 2019, In : VideoGIE. 4, 7, p. 285-299 15 p.

Research output: Contribution to journal › Article

Open Access

Endoscopic Hemostasis

Hemorrhage

Equipment and Supplies

Hemostatics

Surgical Instruments