Gastroenterology and Hepatology

Research Output 1978 2019

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2019

Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression

Hasselluhn, M. C., Schmidt, G. E., Ellenrieder, V., Johnsen, S. & Hessmann, E., Jun 1 2019, In : Cell Death and Disease. 10, 6, 446.

Research output: Contribution to journalArticle

Open Access
Transforming Growth Factors
Pancreatic Neoplasms
Adenocarcinoma
Apoptosis
Growth

Advances in the diagnosis and surveillance of Barrett's esophagus (with videos)

The ASGE Technology Committee, Jan 1 2019, In : Gastrointestinal endoscopy.

Research output: Contribution to journalArticle

Barrett Esophagus
Technology
Biomarkers
Adenocarcinoma
Fluorescence In Situ Hybridization

ARID1A facilitates KRAS signaling-regulated enhancer activity in an AP1-dependent manner in colorectal cancer cells

Sen, M., Wang, X., Hamdan, F. H., Rapp, J., Eggert, J., Kosinsky, R. L., Wegwitz, F., Kutschat, A. P., Younesi, F. S., Gaedcke, J., Grade, M., Hessmann, E., Papantonis, A., Stróbel, P. & Johnsen, S., Jun 19 2019, In : Clinical Epigenetics. 11, 1, 92.

Research output: Contribution to journalArticle

Open Access
Colorectal Neoplasms
Protein Domains
Cell Line
Neoplasms
Transcription Factors
2 Citations (Scopus)

ASGE EndoVators Summit: simulators and the future of endoscopic training

Walsh, C. M., Cohen, J., Woods, K. L., Wang, K. K. N., Andersen, D. K., Anderson, M. A., Dunkin, B. J., Edmundowicz, S. A., Faigel, D. O., Law, J. K., Marks, J. M., Sedlack, R. E., Thompson, C. C. & Vargo, J. J., Jul 1 2019, In : Gastrointestinal endoscopy. 90, 1, p. 13-26 14 p.

Research output: Contribution to journalArticle

Gastrointestinal Endoscopy
Endoscopy
Consensus
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Medicine

ASGE guideline for endoscopic full-thickness resection and submucosal tunnel endoscopic resection

Prepared by: ASGE TECHNOLOGY COMMITTEE, Jan 1 2019, In : VideoGIE.

Research output: Contribution to journalArticle

Open Access
Serous Membrane
Guidelines
Neoplasms
Fibrosis
Equipment and Supplies
1 Citation (Scopus)

ASGE principles of endoscopic training

Chair of 2017-18 ASGE Training Committee, Jul 1 2019, In : Gastrointestinal endoscopy. 90, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Gastrointestinal Endoscopy
Endoscopy
Teaching
Learning
Mental Competency
2 Citations (Scopus)

Barrett esophagus length, nodularity, and low-grade dysplasia are predictive of progression to esophageal adenocarcinoma

Solanky, D., Krishnamoorthi, R., Crews, N., Johnson, M., Wang, K. K. N., Wolfsen, H., Fleischer, D., Ramirez, F. C., Katzka, D. A., Buttar, N. S. & Iyer, P. G., May 1 2019, In : Journal of clinical gastroenterology. 53, 5, p. 361-365 5 p.

Research output: Contribution to journalArticle

Barrett Esophagus
Adenocarcinoma
Confidence Intervals
Biopsy
Proportional Hazards Models

Carboxyl Ester Lipase May Not Mediate Lipotoxic Injury during Severe Acute Pancreatitis

Khatua, B., Trivedi, R. N., Noel, P., Patel, K., Singh, R. J., de Oliveira, C., Trivedi, S., Mishra, V., Lowe, M. & Singh, V. P., Jun 1 2019, In : American Journal of Pathology. 189, 6, p. 1226-1240 15 p.

Research output: Contribution to journalArticle

Lipase
Pancreatitis
Esters
Fat Necrosis
Wounds and Injuries

Characterization of farnesyl diphosphate farnesyl transferase 1 expression in cancer

Tüzmen, Ş., Hostetter, G., Watanabe, A., Ekmekçi, C., Carrigan, P. E., Shechter, I., Kallioniemi, O., Miller, L. J. & Mousses, S., Jan 1 2019, In : Personalized Medicine. 16, 1, p. 51-65 15 p.

Research output: Contribution to journalArticle

Transferases
Neoplasms
Cholesterol
Enzymes
Metabolic Networks and Pathways

Clinical and Molecular Features of Post-Colonoscopy Colorectal Cancers

Samadder, N. J., Neklason, D., Snow, A., Samowitz, W., Cessna, M. H., Rowe, K., Sandhu, I., Boucher, K., Pappas, L., Smith, K. R., Wong, J., Curtin, K., Provenzale, D. & Burt, R. W., Jan 1 2019, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Colonoscopy
Colorectal Neoplasms
Carcinogenesis
Neoplasms
Microsatellite Instability
Open Access
Narrow Band Imaging
Barrett Esophagus
Lasers
1 Citation (Scopus)

Devices for endoscopic hemostasis of nonvariceal GI bleeding (with videos)

ASGE Technology Committee Chair & ASGE Technology Committee, Jul 1 2019, In : VideoGIE. 4, 7, p. 285-299 15 p.

Research output: Contribution to journalArticle

Open Access
Endoscopic Hemostasis
Hemorrhage
Equipment and Supplies
Hemostatics
Surgical Instruments

Effervescent agents in acute esophageal food impaction

David, J., Backstedt, D., O’Keefe, K. J., Salehpour, K., Gerkin, R. D. & Ramirez, F. C., Jan 1 2019, In : Diseases of the Esophagus. 32, 4

Research output: Contribution to journalArticle

Open Access
Food
Glucagon
Costs and Cost Analysis
Hospitalization
Therapeutics
5 Citations (Scopus)

Efficacy of Per-oral Methylene Blue Formulation for Screening Colonoscopy

Repici, A., Wallace, M. B., East, J. E., Sharma, P., Ramirez, F. C., Bruining, D. H., Young, M., Gatof, D., Irene (Mimi) Canto, M., Marcon, N., Cannizzaro, R., Kiesslich, R., Rutter, M., Dekker, E., Siersema, P. D., Spaander, M., Kupcinskas, L., Jonaitis, L., Bisschops, R., Radaelli, F. & 8 others, Bhandari, P., Wilson, A., Early, D., Gupta, N., Vieth, M., Lauwers, G. Y., Rossini, M. & Hassan, C., Jun 1 2019, In : Gastroenterology. 156, 8, p. 2198-2207.e1

Research output: Contribution to journalArticle

Methylene Blue
Colonoscopy
Placebos
Adenoma
Odds Ratio
2 Citations (Scopus)

Endoscopic simulators

ASGE Technology Committee, Jul 1 2019, In : Gastrointestinal endoscopy. 90, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Endoscopy
Animal Models
Education
Clinical Competence
Gastroenterology

Epigenome mapping identifies tumor-specific gene expression in primary rectal cancer

Flebbe, H., Hamdan, F. H., Kari, V., Kitz, J., Gaedcke, J., Ghadimi, B. M., Johnsen, S. & Grade, M., Aug 1 2019, In : Cancers. 11, 8, 1142.

Research output: Contribution to journalArticle

Open Access
Chromatin Immunoprecipitation
Rectal Neoplasms
Gene Expression
Mucous Membrane
Neoplasms

Factors Associated With Use of Nonoral Nutrition and Hydration Support in Adult Patients With Postural Tachycardia Syndrome

Tseng, A. S., Traub, N. A., Harris, L. A., Crowell, M. D., Hoffman-Snyder, C. R., Goodman, B. P. & DiBaise, J. D., Jan 1 2019, In : Journal of Parenteral and Enteral Nutrition. 43, 6, p. 734-741 8 p.

Research output: Contribution to journalArticle

Postural Orthostatic Tachycardia Syndrome
Parenteral Nutrition
Enteral Nutrition
Opiate Alkaloids
Delivery of Health Care

Familial pancreatic cancer risk: a population-based study in Utah

Kohli, D. R., Smith, K. R., Wong, J., Yu, Z., Boucher, K., Faigel, D. O., Pannala, R., Burt, R. W., Curtin, K. & Samadder, N. J., Jan 1 2019, In : Journal of Gastroenterology.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Pancreas
Adenocarcinoma
Population
Population Control
4 Citations (Scopus)

Family History Associates With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases

Samadder, N. J., Valentine, J. F., Guthery, S., Singh, H., Bernstein, C. N., Leighton, J. A., Wan, Y., Wong, J., Boucher, K., Pappas, L., Rowe, K., Burt, R. W., Curtin, K. & Smith, K. R., Jan 1 2019, In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Colorectal Neoplasms
Incidence
Population Surveillance
Databases

Intestinal metaplasia of the gastric cardia: findings in patients with versus without Barrett's esophagus

Siddiki, H. A., Lam-Himlin, D. M., Kahn, A., Bandres, M. V., Burdick, G. E., Crowell, M. D., Pannala, R., Ramirez, F. C., Vela, M. F. & Fleischer, D. E., Jan 1 2019, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

Cardia
Barrett Esophagus
Metaplasia
Stomach
Biopsy
3 Citations (Scopus)

Loss of rnf40 decreases nf-κb activity in colorectal cancer cells and reduces colitis burden in mice

Kosinsky, R. L., Chua, R. L., Qui, M., Saul, D., Mehlich, D., Ströbel, P., Schildhaus, H. U., Wegwitz, F., Faubion, W. A. & Johnsen, S., Mar 26 2019, In : Journal of Crohn's and Colitis. 13, 3, p. 362-373 12 p.

Research output: Contribution to journalArticle

Colitis
Colorectal Neoplasms
Inflammation
Colon
Phenotype

Mental Health Disorders are More Common in Colorectal Cancer Survivors and Associated with Decreased Overall Survival

Lloyd, S., Baraghoshi, D., Tao, R., Garrido-Laguna, I., Gilcrease, G. W., Whisenant, J., Weis, J. R., Scaife, C., Pickron, T. B., Huang, L. C., Monroe, M. M., Abdelaziz, S., Fraser, A. M., Smith, K. R., Deshmukh, V., Newman, M., Rowe, K. G., Snyder, J., Samadder, N. J. & Hashibe, M., Jan 1 2019, In : American Journal of Clinical Oncology: Cancer Clinical Trials.

Research output: Contribution to journalArticle

Mental Disorders
Survivors
Colorectal Neoplasms
Mental Health
Survival

Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor

Desai, A. J., Mechin, I., Nagarajan, K., Valant, C., Wootten, D., Lam, P. C. H., Orry, A., Abagyan, R., Nair, A., Sexton, P. M., Christopoulos, A. & Miller, L. J., Mar 1 2019, In : Molecular Pharmacology. 95, 3, p. 245-259 15 p.

Research output: Contribution to journalArticle

Cholecystokinin
Structure-Activity Relationship
Cholecystokinin Receptors
Peptides
Structural Models

Multimodal Transgastric Local Pancreatic Hypothermia Reduces Severity of Acute Pancreatitis in Rats and Increases Survival

de Oliveira, C., Khatua, B., Bag, A., El-Kurdi, B., Patel, K., Mishra, V., Navina, S. & Singh, V. P., Feb 1 2019, In : Gastroenterology. 156, 3, p. 735-747.e10

Research output: Contribution to journalArticle

Hypothermia
Pancreatitis
Linoleic Acid
Ceruletide
Acinar Cells
1 Citation (Scopus)

Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients with Inflammatory Bowel Disease

Wang, M. H., Friton, J. J., Raffals, L. E. H., Leighton, J. A., Pasha, S. F., Picco, M. F., Cushing, K. C., Monroe, K., Nix, B. D., Newberry, R. D. & Faubion, W. A., Aug 14 2019, In : Journal of Crohn's and Colitis. 13, 8, p. 1036-1043 8 p., jjz017.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Tumor Necrosis Factor-alpha
Genetic Loci
Odds Ratio
Therapeutics
3 Citations (Scopus)

Organ Failure Due to Systemic Injury in Acute Pancreatitis

Garg, P. K. & Singh, V. P., May 1 2019, In : Gastroenterology. 156, 7, p. 2008-2023 16 p.

Research output: Contribution to journalArticle

Pancreatitis
Wounds and Injuries
Causality
Sepsis
Therapeutics
1 Citation (Scopus)

Perturbing enhancer activity in cancer therapy

Hamdan, F. H. & Johnsen, S., May 1 2019, In : Cancers. 11, 5, 634.

Research output: Contribution to journalArticle

Open Access
Neoplasms
Therapeutics
Thiazolidinediones
Cyclin-Dependent Kinases
Cyclosporine
2 Citations (Scopus)

Predictors of Biliary Strictures After Liver Transplantation Among Recipients of DCD (Donation After Cardiac Death) Grafts

Kohli, D. R., Harrison, M. E., Adike, A. O., El Kurdi, B., Fukami, N., Faigel, D. O., Pannala, R., Moss, A. A. & Aqel, B. A., Jan 1 2019, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Liver Transplantation
Pathologic Constriction
Transplants
Endoscopic Retrograde Cholangiopancreatography
International Normalized Ratio

Radiopathological correlation of a von Hippel-Lindau syndrome associated pancreatic neuroendocrine tumour with clear cell features

Hopp, A. C., Collins, J. M., Nguyen, C. C. & Yang, M., Feb 1 2019, In : BMJ Case Reports. 12, 2, e227891.

Research output: Contribution to journalArticle

von Hippel-Lindau Disease
Neuroendocrine Tumors
Radiology
Pancreatic Cyst
Paclitaxel
Alcohols
Safety

The Clinician's Guide to Suspected Small Bowel Bleeding

Kuo, J. R., Pasha, S. F. & Leighton, J. A., Apr 1 2019, In : The American Journal of Gastroenterology. 114, 4, p. 591-598 8 p.

Research output: Contribution to journalArticle

Hemorrhage
Capsule Endoscopy
Equipment and Supplies
1 Citation (Scopus)

The E3 ubiquitin ligase RNF40 suppresses apoptosis in colorectal cancer cells

Schneider, D., Chua, R. L., Molitor, N., Hamdan, F. H., Rettenmeier, E. M., Prokakis, E., Mishra, V. K., Kari, V., Wegwitz, F., Johnsen, S. & Kosinsky, R. L., Jul 2 2019, In : Clinical Epigenetics. 11, 1, 98.

Research output: Contribution to journalArticle

Open Access
Ubiquitin-Protein Ligases
Colorectal Neoplasms
Apoptosis
Proteins
Caspase 7
1 Citation (Scopus)

The Utility of Screening for Coccidioidomycosis in Recipients of Inhibitors of Tumor Necrosis Factor α

Choi, K., Deval, N., Vyas, A., Moran, C., Cha, S. S., Mertz, L. E., Pasha, S. F., Yiannias, J. A. & Blair, J. E., Mar 5 2019, In : Clinical Infectious Diseases. 68, 6, p. 1024-1030 7 p.

Research output: Contribution to journalArticle

Coccidioidomycosis
Tumor Necrosis Factor-alpha
Infection
Coccidioides
Mycoses

USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activity

Kosinsky, R. L., Zerche, M., Saul, D., Wang, X., Wohn, L., Wegwitz, F., Begus-Nahrmann, Y. & Johnsen, S. A., Jan 1 2019, (Accepted/In press) In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Neoplasms
Carcinogenesis
Survival
Neoplasm Genes

Variation in Endoscopic Activity Assessment and Endoscopy Score Validation in Adults With Eosinophilic Esophagitis

International EEsAI Study Group, Jul 1 2019, In : Clinical Gastroenterology and Hepatology. 17, 8, p. 1477-1488.e10

Research output: Contribution to journalArticle

Eosinophilic Esophagitis
Endoscopy
Placebos
Exudates and Transudates
Linear Models
2018
9 Citations (Scopus)

Acute Liver Failure of Indeterminate Etiology: A Comprehensive Systematic Approach by An Expert Committee to Establish Causality

for the Acute Liver Failure Study Group, Jun 27 2018, (Accepted/In press) In : American Journal of Gastroenterology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Acute Liver Failure
Acetaminophen
Causality
Chemical and Drug Induced Liver Injury
Metagenomics
27 Citations (Scopus)

American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome

for the ACG Task Force on Management of Irritable Bowel Syndrome, Jun 27 2018, (Accepted/In press) In : American Journal of Gastroenterology. p. 1-18 18 p.

Research output: Contribution to journalArticle

Irritable Bowel Syndrome
Gastroenterology
16 Citations (Scopus)

American Gastroenterological Association Institute Clinical Practice Update: Endoscopic Submucosal Dissection in the United States

Draganov, P. V., Wang, A. Y., Othman, M. O. & Fukami, N., Jan 1 2018, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Practice Guidelines
Endoscopic Mucosal Resection
Neoplasms
Educational Models
Lymph Nodes
6 Citations (Scopus)

Association of sulindac and erlotinib vs placebo with colorectal neoplasia in familial adenomatous polyposis: Secondary analysis of a randomized clinical trial

Samadder, N. J., Kuwada, S. K., Boucher, K. M., Byrne, K., Kanth, P., Samowitz, W., Jones, D., Tavtigian, S. V., Westover, M., Berry, T., Jasperson, K., Pappas, L., Smith, L., Sample, D., Burt, R. W. & Neklason, D. W., May 1 2018, In : JAMA oncology. 4, 5, p. 671-677 7 p.

Research output: Contribution to journalArticle

Sulindac
Adenomatous Polyposis Coli
Polyps
Randomized Controlled Trials
Placebos

Association of total fluid intake and output with duration of hospital stay in patients with acute pancreatitis

Koop, A. H., Stancampiano, F. F., Jackson, J., Henry, A., Horsley-Silva, J., Pannala, R., Heckman, M. G., Diehl, N. N. & Palmer, W. C., Jan 1 2018, In : Gastroenterology Research and Practice. 2018, 7614381.

Research output: Contribution to journalArticle

Pancreatitis
Length of Stay
Water-Electrolyte Balance
Urine
Statistical Models
2 Citations (Scopus)

Better Understanding and Recognition of the Disconnects, Experiences, and Needs of Patients with Irritable Bowel Syndrome with Constipation (BURDEN IBS-C) Study: Results of an Online Questionnaire

Quigley, E. M. M., Horn, J., Kissous-Hunt, M., Crozier, R. A. & Harris, L. A., Jun 26 2018, (Accepted/In press) In : Advances in Therapy. p. 1-14 14 p.

Research output: Contribution to journalArticle

Irritable Bowel Syndrome
Constipation
Health Personnel
Time and Motion Studies
Prescriptions
1 Citation (Scopus)

Biliary and pancreatic lithotripsy devices

ASGE Technology Committee, Jan 1 2018, (Accepted/In press) In : VideoGIE.

Research output: Contribution to journalArticle

Lithotripsy
Equipment and Supplies
Laser Lithotripsy
Pancreatic Ducts
Shock
2 Citations (Scopus)

Clinical features and long-term outcomes of lower esophageal sphincter-dependent and lower esophageal sphincter-independent jackhammer esophagus

Kahn, A., Al-Qaisi, M. T., Obeid, R. A., Katzka, D. A., Ravi, K. M., Ramirez, F. C., Crowell, M. D. & Vela, M. F., Jan 1 2018, (Accepted/In press) In : Neurogastroenterology and Motility. e13507.

Research output: Contribution to journalArticle

Lower Esophageal Sphincter
Esophagus
Deglutition Disorders
Accidental Falls
Swallows
9 Citations (Scopus)

Clinical Practice Guideline on Screening for Colorectal Cancer in Individuals With a Family History of Nonhereditary Colorectal Cancer or Adenoma: The Canadian Association of Gastroenterology Banff Consensus

Leddin, D., Lieberman, D. A., Tse, F., Barkun, A. N., Abou-Setta, A. M., Marshall, J. K., Samadder, N. J., Singh, H., Telford, J. J., Tinmouth, J., Wilkinson, A. N. & Leontiadis, G. I., Nov 1 2018, In : Gastroenterology. 155, 5, p. 1325-1347.e3

Research output: Contribution to journalArticle

Practice Guidelines
Adenoma
Colorectal Neoplasms
Consensus
Colonoscopy
3 Citations (Scopus)

Clinical utility of gastric emptying scintigraphy: Patient and physician perspectives

Tseng, A. S., Crowell, M. D. & DiBaise, J. K., May 1 2018, In : Neurogastroenterology and Motility. 30, 5, e13279.

Research output: Contribution to journalArticle

Gastric Emptying
Radionuclide Imaging
Physicians
Quality of Life
Gastroparesis

Comparison of Small Versus Large Volume Split Dose Preparation for Colonoscopy: A Study of Colonoscopy Outcomes

Siddiki, H., Ravi, S., Al-Qaisi, M. T., Fath, A. R., Ramirez, F. C., Crowell, M. D., Pannala, R., Faigel, D. O. & Gurudu, S. R., May 7 2018, (Accepted/In press) In : Digestive Diseases and Sciences. p. 1-6 6 p.

Research output: Contribution to journalArticle

Colonoscopy
Polyps
Outcome Assessment (Health Care)
Adenoma
Constipation
22 Citations (Scopus)

Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor

Liang, Y. L., Khoshouei, M., Deganutti, G., Glukhova, A., Koole, C., Peat, T. S., Radjainia, M., Plitzko, J. M., Baumeister, W., Miller, L. J., Hay, D. L., Christopoulos, A., Reynolds, C. A., Wootten, D. & Sexton, P. M., Sep 27 2018, In : Nature. 561, 7724, p. 492-497 6 p.

Research output: Contribution to journalArticle

Calcitonin Receptor-Like Protein
Calcitonin Gene-Related Peptide Receptors
Receptor Activity-Modifying Protein 1
Calcitonin Gene-Related Peptide
G-Protein-Coupled Receptors

c-Src regulates cargo transit via the Golgi in pancreatic acinar cells

Kostenko, S., Heu, C. C., Yaron, J. R., Singh, G., de Oliveira, C., Muller, W. J. & Singh, V. P., Dec 1 2018, In : Scientific Reports. 8, 1, 11903.

Research output: Contribution to journalArticle

Acinar Cells
Secretory Vesicles
Amylases
Pancreatitis
Staining and Labeling
1 Citation (Scopus)

Devices and methods to improve colonoscopy completion (with videos)

ASGE Technology Committee, Mar 1 2018, In : Gastrointestinal Endoscopy. 87, 3, p. 688-694.e2

Research output: Contribution to journalArticle

Colonoscopy
Equipment and Supplies

Do recent reports about the adverse effects of proton pump inhibitors change providers' prescription practice?

Al-Qaisi, M. T., Kahn, A., Crowell, M. D., Burdick, G. E., Vela, M. F. & Ramirez, F. C., Oct 30 2018, In : Diseases of the Esophagus. 31, 12, doy042.

Research output: Contribution to journalArticle

Open Access
Proton Pump Inhibitors
Prescriptions
Consultants
Clostridium Infections
Clostridium difficile