Family Medicine

Research Output 1996 2019

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2006
30 Citations (Scopus)

Association of B-type natriuretic peptide activation to left ventricular end-systolic remodeling in organic and functional mitral regurgitation

Detaint, D., Messika-Zeitoun, D., Chen, H. H., Rossi, A., Avierinos, J. F., Scott, C., Burnett, J. C. J. & Sarano, M. E., Apr 1 2006, In : American Journal of Cardiology. 97, 7, p. 1029-1034 6 p.

Research output: Contribution to journal › Article

Brain Natriuretic Peptide
Mitral Valve Insufficiency
Biomarkers
Ventricular Remodeling
Doppler Echocardiography
22 Citations (Scopus)

Clinical application of the natriuretic peptides in heart failure

Chen, H. H. & Burnett, J. C. J., Sep 2006, In : European Heart Journal, Supplement. 8, E

Research output: Contribution to journal › Article

Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Snake Venoms
C-Type Natriuretic Peptide
12 Citations (Scopus)

Exertional Changes in Circulating Cardiac Natriuretic Peptides in Patients with Suggested Coronary Artery Disease

Bergeron, S., Møller, J. E., Bailey, K. R., Chen, H. H., Burnett, J. C. J. & Pellikka, P., Jun 2006, In : Journal of the American Society of Echocardiography. 19, 6, p. 772-776 5 p.

Research output: Contribution to journal › Article

Natriuretic Peptides
Brain Natriuretic Peptide
Coronary Artery Disease
Exercise
Atrial Natriuretic Factor
15 Citations (Scopus)

Intact acute cardiorenal and humoral responsiveness following chronic subcutaneous administration of the cardiac peptide BNP in experimental heart failure

Chen, H. H., Schirger, J. A., Cataliotti, A. & Burnett, J. C. J., Nov 2006, In : European Journal of Heart Failure. 8, 7, p. 681-686 6 p.

Research output: Contribution to journal › Article

Heart Failure
Dogs
Peptides
Second Messenger Systems
Hemodynamics
42 Citations (Scopus)

Lack of activation of molecular forms of the BNP system in human grade 1 hypertension and relationship to cardiac hypertrophy

Belluardo, P., Cataliotti, A., Bonaiuto, L., Giuffré, E., Maugeri, E., Noto, P., Orlando, G., Raspa, G., Piazza, B., Babuin, L., Chen, H. H., Martin, F. L., McKie, P., Heublein, D. M., Burnett, J. C. J. & Malatino, L. S., 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 291, 4

Research output: Contribution to journal › Article

Cardiomegaly
Hypertension
pro-brain natriuretic peptide (1-76)
Brain Natriuretic Peptide
Left Ventricular Hypertrophy
39 Citations (Scopus)

Maximizing the renal cyclic 3′-5′-guanosine monophosphate system with type V phosphodiesterase inhibition and exogenous natriuretic peptide: A novel strategy to improve renal function in experimental overt heart failure

Chen, H. H., Huntley, B. K., Schirger, J. A., Cataliotti, A. & Burnett, J. C. J., Oct 2006, In : Journal of the American Society of Nephrology. 17, 10, p. 2742-2747 6 p.

Research output: Contribution to journal › Article

Type 5 Cyclic Nucleotide Phosphodiesterases
Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Cyclic GMP
12 Citations (Scopus)

Natriuretic Peptides as Regulators of Myocardial Structure and Function: Pathophysiologic and Therapeutic Implications

Cataliotti, A., Chen, H. H., Redfield, M. M. & Burnett, J. C. J., Jul 2006, In : Heart Failure Clinics. 2, 3, p. 269-276 8 p.

Research output: Contribution to journal › Article

Natriuretic Peptides
Atrial Natriuretic Factor
Cardiac Myocytes
Cardiovascular Diseases
Heart Failure
38 Citations (Scopus)

Pathophysiology of Volume Overload in Acute Heart Failure Syndromes

Chen, H. H. & Schrier, R. W., Dec 2006, In : American Journal of Medicine. 119, 12 SUPPL.

Research output: Contribution to journal › Article

Heart Failure
Pulmonary Wedge Pressure
Arginine Vasopressin
Sympathetic Nervous System
Renin-Angiotensin System
8 Citations (Scopus)

Therapeutic Potential for Existing and Novel Forms of Natriuretic Peptides

Chen, H. H. & Burnett, J. C. J., Jul 2006, In : Heart Failure Clinics. 2, 3, p. 365-373 9 p.

Research output: Contribution to journal › Article

Natriuretic Peptides
Heart Failure
Hormones
Peptides
Therapeutics
2005
129 Citations (Scopus)

B-type natriuretic peptide in organic mitral regurgitation: Determinants and impact on outcome

Detaint, D., Messika-Zeitoun, D., Avierinos, J. F., Scott, C., Chen, H. H., Burnett, J. C. J. & Sarano, M. E., May 10 2005, In : Circulation. 111, 18, p. 2391-2397 7 p.

Research output: Contribution to journal › Article

Brain Natriuretic Peptide
Mitral Valve Insufficiency
Multivariate Analysis
Heart Failure
Ventricular Remodeling
17 Citations (Scopus)

Consensus-degenerate hybrid oligonucleotide primers (CODEHOP) for the detection of novel papillomaviruses and their application to esophageal and tonsillar carcinomas

Baines, J., McGovern, R. M., Persing, D. & Gostout, B. S., Jan 1 2005, In : Journal of Virological Methods. 123, 1, p. 81-87 7 p.

Research output: Contribution to journal › Article

DNA Primers
Carcinoma
Neoplasms
Conserved Sequence
Esophagus
33 Citations (Scopus)

Equimolar doses of atrial and brain natriuretic peptides and urodilatin have differential renal actions in overt experimental heart failure

Chen, H. H., Cataliotti, A., Schirger, J. A., Martin, F. L. & Burnett, J. C. J., May 2005, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 288, 5 57-5

Research output: Contribution to journal › Article

Brain Natriuretic Peptide
Atrial Natriuretic Factor
Heart Failure
Kidney
Natriuretic Peptides
54 Citations (Scopus)

Oral human brain natriuretic peptide activates cyclic guanosine 3′,5′-monophosphate and decreases mean arterial pressure

Cataliotti, A., Schirger, J. A., Martin, F. L., Chen, H. H., McKie, P., Boerrigter, G., Costello-Boerrigter, L. C., Harty, G., Heublein, D. M., Sandberg, S. M., James, K. D., Miller, M. A., Malkar, N. B., Polowy, K. & Burnett, J. C. J., Aug 9 2005, In : Circulation. 112, 6, p. 836-840 5 p.

Research output: Contribution to journal › Article

Guanosine Monophosphate
Brain Natriuretic Peptide
Arterial Pressure
Oral Administration
Dogs

Renal and humoral pathophysiological actions of angiotensin II in congestive heart failure

Mirzoyev, Z., Anavekar, N. S. & Chen, H. H., Feb 2005, In : Drugs of Today. 41, 2, p. 129-139 11 p.

Research output: Contribution to journal › Article

Angiotensins
Angiotensin II
Heart Failure
Renin-Angiotensin System
Kidney
2004

76-Year-old woman with chest pain

Krajicek, B. J. & Chen, H. H., 2004, In : Mayo Clinic Proceedings. 79, 11, p. 1435-1438 4 p.

Research output: Contribution to journal › Article

Chest Pain
81 Citations (Scopus)

Brain Natriuretic Peptide Enhances Renal Actions of Furosemide and Suppresses Furosemide-Induced Aldosterone Activation in Experimental Heart Failure

Cataliotti, A., Boerrigter, G., Costello-Boerrigter, L. C., Schirger, J. A., Tsuruda, T., Heublein, D. M., Chen, H. H., Malatino, L. S. & Burnett, J. C. J., Apr 6 2004, In : Circulation. 109, 13, p. 1680-1685 6 p.

Research output: Contribution to journal › Article

Brain Natriuretic Peptide
Furosemide
Aldosterone
Heart Failure
Kidney
26 Citations (Scopus)

Endothelin A Receptor Antagonism in Experimental Congestive Heart Failure Results in Augmentation of the Renin-Angiotensin System and Sustained Sodium Retention

Schirger, J. A., Chen, H. H., Jougasaki, M., Lisy, O., Boerrigter, G., Cataliotti, A. & Burnett, J. C. J., Jan 20 2004, In : Circulation. 109, 2, p. 249-254 6 p.

Research output: Contribution to journal › Article

Endothelin A Receptors
Renin-Angiotensin System
Heart Failure
Sodium
Endothelin-1
56 Citations (Scopus)

Subcutaneous administration of the cardiac hormone BNP in symptomatic human heart failure

Chen, H. H., Redfield, M. M., Nordstrom, L. J., Horton, D. P. & Burnett, J. C. J., Apr 2004, In : Journal of Cardiac Failure. 10, 2, p. 115-119 5 p.

Research output: Contribution to journal › Article

Brain Natriuretic Peptide
Heart Failure
Hormones
Cyclic GMP
Natriuresis
2003
25 Citations (Scopus)

Angiotensin II AT1 receptor antagonism prevents detrimental renal actions of acute diuretic therapy in human heart failure

Chen, H. H., Redfield, M. M., Nordstrom, L. J., Cataliotti, A. & Burnett, J. C. J., May 1 2003, In : American Journal of Physiology - Renal Physiology. 284, 5 53-5

Research output: Contribution to journal › Article

Angiotensin Type 1 Receptor
Angiotensin Receptors
Diuretics
Glomerular Filtration Rate
Losartan
95 Citations (Scopus)

Immune-mediated tumor regression induced by CpG-containing oligodeoxynucleotides

Baines, J. & Celis, E., Jul 1 2003, In : Clinical Cancer Research. 9, 7, p. 2693-2700 8 p.

Research output: Contribution to journal › Article

Oligodeoxyribonucleotides
T-Lymphocytes
Neoplasms
Carcinoma
Histocompatibility Antigens Class I
15 Citations (Scopus)

Leukemia inhibitory factor is augmented in the heart in experimental heart failure

Jougasaki, M., Leskinen, H., Larsen, A. M., Cataliotti, A., Chen, H. H. & Burnett, J. C. J., Mar 2003, In : European Journal of Heart Failure. 5, 2, p. 137-145 9 p.

Research output: Contribution to journal › Article

Leukemia Inhibitory Factor
Heart Failure
Messenger RNA
Heart Atria
Canidae
56 Citations (Scopus)

Use of plasma brain natriuretic peptide concentration to aid in the diagnosis of heart failure

Shapiro, B. P., Chen, H. H., Burnett, J. C. J. & Redfield, M. M., Apr 1 2003, In : Mayo Clinic Proceedings. 78, 4, p. 481-486 6 p.

Research output: Contribution to journal › Article

Brain Natriuretic Peptide
Heart Failure
Confounding Factors (Epidemiology)
Triage
United States Food and Drug Administration
2002
235 Citations (Scopus)

Brain natriuretic peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases

Tsuruda, T., Boerrigter, G., Huntley, B. K., Noser, J. A., Cataliotti, A., Costello-Boerrigter, L. C., Chen, H. H. & Burnett, J. C. J., Dec 2002, In : Circulation Research. 91, 12, p. 1127-1134 8 p.

Research output: Contribution to journal › Article

Brain Natriuretic Peptide
Matrix Metalloproteinases
Fibroblasts
Matrix Metalloproteinase 2
Cyclic GMP-Dependent Protein Kinases
74 Citations (Scopus)

Cardiotrophin-1 stimulation of cardiac fibroblast growth: Roles for glycoprotein 130/leukemia inhibitory factor receptor and the endothelin type A receptor

Tsuruda, T., Jougasaki, M., Boerrigter, G., Huntley, B. K., Chen, H. H., D'Assoro, A., Lee, S. C., Larsen, A. M., Cataliotti, A. & Burnett, J. C. J., Feb 8 2002, In : Circulation Research. 90, 2, p. 128-134 7 p.

Research output: Contribution to journal › Article

OSM-LIF Receptors
Endothelin A Receptors
Glycoproteins
Fibroblasts
Growth
40 Citations (Scopus)

Differential actions of vasopeptidase inhibition versus angiotensin-converting enzyme inhibition on diuretic therapy in experimental congestive heart failure

Cataliotti, A., Boerrigter, G., Chen, H. H., Jougasaki, M., Costello, L. C., Tsuruda, T., Lee, S. C., Malatino, L. S. & Burnett, J. C. J., Feb 5 2002, In : Circulation. 105, 5, p. 639-644 6 p.

Research output: Contribution to journal › Article

Investigational Therapies
Peptidyl-Dipeptidase A
Diuretics
Heart Failure
Aldosterone
44 Citations (Scopus)

Maximizing the natriuretic peptide system in experimental heart failure: Subcutaneous brain natriuretic peptide and acute vasopeptidase inhibition

Chen, H. H., Lainchbury, J. G., Harty, G. J. & Burnett, J. C. J., Feb 26 2002, In : Circulation. 105, 8, p. 999-1003 5 p.

Research output: Contribution to journal › Article

Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Neprilysin
57 Citations (Scopus)

Natriuretic peptide receptors and neutral endopeptidase in mediating the renal actions of a new therapeutic synthetic natriuretic peptide dendroaspis natriuretic peptide

Chen, H. H., Lainchbury, J. G. & Burnett, J. C. J., Sep 18 2002, In : Journal of the American College of Cardiology. 40, 6, p. 1186-1191 6 p.

Research output: Contribution to journal › Article

Neprilysin
Natriuretic Peptides
Peptide Receptors
Kidney
Protease Inhibitors
2001
47 Citations (Scopus)

Endogenous natriuretic peptides participate in renal and humoral actions of acute vasopeptidase inhibition in experimental mild heart failure

Chen, H. H., Lainchbury, J. G., Matsuda, Y., Harty, G. J. & Burnett, J. C. J., 2001, In : Hypertension. 38, 2, p. 187-191 5 p.

Research output: Contribution to journal › Article

Natriuretic Peptides
Atrial Natriuretic Factor
Brain Natriuretic Peptide
Heart Failure
Kidney
4 Citations (Scopus)

Role of the natriuretic peptides in the cardiorenal and humoral actions of omapatrilat: Insights from experimental heart failure

Chen, H. H., Cataliotti, A. & Burnett, J. C. J., 2001, In : Current Hypertension Reports. 3, SUPPL. 2

Research output: Contribution to journal › Article

Natriuretic Peptides
Heart Failure
Peptidyl-Dipeptidase A
Neprilysin
Peptide Receptors
2000
18 Citations (Scopus)

Comparison of the efficacy of betaxolol-brinzolamide and timolol- dorzolamide as suppressors of aqueous humor flow in human subjects

Brubaker, R. F., Ingram, C., Schoff, E. O. & Nau, C. B., Feb 1 2000, In : Ophthalmology. 107, 2, p. 283-287 5 p.

Research output: Contribution to journal › Article

dorzolamide
Betaxolol
Timolol
Aqueous Humor
Intraocular Pressure
97 Citations (Scopus)

Natriuretic peptides in the pathophysiology of congestive heart failure

Chen, H. H. & Burnett, J. C. J., 2000, In : Current Cardiology Reports. 2, 3, p. 198-205 8 p.

Research output: Contribution to journal › Article

Natriuretic Peptides
Brain Natriuretic Peptide
Atrial Natriuretic Factor
C-Type Natriuretic Peptide
Heart Failure
63 Citations (Scopus)

Subcutaneous administration of brain natriuretic peptide in experimental heart failure

Chen, H. H., Grantham, J. A., Schirger, J. A., Jougasaki, M., Redfield, M. M. & Burnett, J. C. J., Nov 1 2000, In : Journal of the American College of Cardiology. 36, 5, p. 1706-1712 7 p.

Research output: Contribution to journal › Article

Brain Natriuretic Peptide
Heart Failure
Pulmonary Wedge Pressure
Renal Circulation
Cyclic GMP
7 Citations (Scopus)

The modulating actions of sulfonylurea on atrial natriuretic peptide release in experimental acute heart failure

Chen, H. H., Oh, K. Y., Terzic, A. & Burnett, J. C. J., Mar 1 2000, In : European Journal of Heart Failure. 2, 1, p. 33-40 8 p.

Research output: Contribution to journal › Article

Atrial Natriuretic Factor
Heart Failure
Glyburide
Adenosine Triphosphate
Natriuresis
51 Citations (Scopus)

Vascular actions of brain natriuretic peptide: Modulation by atherosclerosis and neutral endopeptidase inhibition

Schirger, J. A., Grantham, J. A., Kullo, I. J., Jougasaki, M., Wennberg, P. W., Chen, H. H., Lisy, O., Miller, V. M., Simari, R. D. & Burnett, J. C. J., Mar 1 2000, In : Journal of the American College of Cardiology. 35, 3, p. 796-801 6 p.

Research output: Contribution to journal › Article

Neprilysin
Brain Natriuretic Peptide
Blood Vessels
Atherosclerosis
Vascular Smooth Muscle
1999
54 Citations (Scopus)

Effect of brinzolamide and dorzolamide on aqueous humor flow in human eyes

Ingram, C. & Brubaker, R. F., Sep 1 1999, In : American journal of ophthalmology. 128, 3, p. 292-296 5 p.

Research output: Contribution to journal › Article

dorzolamide
Aqueous Humor
Intraocular Pressure
Fluorophotometry
Carbonic Anhydrase Inhibitors
104 Citations (Scopus)

Presence of Dendroaspis natriuretic peptide-like immunoreactivity in human plasma and its increase during human heart failure

Schirger, J. A., Heublein, D. M., Chen, H. H., Lisy, O., Jougasaki, M., Wennberg, P. W. & Burnett, J. C. J., 1999, In : Mayo Clinic Proceedings. 74, 2, p. 126-130 5 p.

Research output: Contribution to journal › Article

Heart Failure
Natriuretic Peptides
Myocardium
C-Type Natriuretic Peptide
Dendroaspis natriuretic peptide
94 Citations (Scopus)

Renal actions of synthetic Dendroaspis natriuretic peptide

Lisy, O., Jougasaki, M., Heublein, D. M., Schirger, J. A., Chen, H. H., Wennberg, P. W. & Burnett, J. C. J., 1999, In : Kidney International. 56, 2, p. 502-508 7 p.

Research output: Contribution to journal › Article

Kidney
Myocardium
Canidae
Elapidae
Brain Natriuretic Peptide
57 Citations (Scopus)

Renal response to acute neutral endopeptidase inhibition in mild and severe experimental heart failure

Chen, H. H., Schirger, J. A., Chau, W. L., Jougasaki, M., Lisy, O., Redfield, M. M., Barclay, P. T. & Burnett, J. C. J., Dec 14 1999, In : Circulation. 100, 24, p. 2443-2448 6 p.

Research output: Contribution to journal › Article

Neprilysin
Heart Failure
Kidney
Atrial Natriuretic Factor
Sodium
138 Citations (Scopus)

The natriuretic peptides in heart failure: Diagnostic and therapeutic potentials

Chen, H. H. & Burnett, J. C. J., 1999, In : Proceedings of the Association of American Physicians. 111, 5, p. 406-416 11 p.

Research output: Contribution to journal › Article

Natriuretic Peptides
Heart Failure
C-Type Natriuretic Peptide
Brain Natriuretic Peptide
Atrial Natriuretic Factor
1998
162 Citations (Scopus)

C-type natriuretic peptide: The endothelial component of the natriuretic peptide system

Chen, H. H. & Burnett, J. C. J., 1998, In : Journal of Cardiovascular Pharmacology. 32, SUPPL. 3

Research output: Contribution to journal › Article

C-Type Natriuretic Peptide
Natriuretic Peptides
Atrial Natriuretic Factor
Vascular Smooth Muscle
Smooth Muscle Myocytes
82 Citations (Scopus)

Neutral endopeptidase inhibition potentiates the natriuretic actions of adrenomedullin

Lisy, O., Jougasaki, M., Schirger, J. A., Chen, H. H., Barclay, P. T. & Burnett, J. C. J., Sep 1998, In : American Journal of Physiology - Renal Physiology. 275, 3 44-3

Research output: Contribution to journal › Article

Adrenomedullin
Neprilysin
Kidney
Sodium
Disulfides
1996

68-Year-old man with anemia and renal failure

Chen, H. H., Shields, R. C. & Bardsley, W. T., 1996, In : Mayo Clinic Proceedings. 71, 2, p. 197-200 4 p.

Research output: Contribution to journal › Article

Renal Insufficiency
Anemia