Family Medicine

Research Output 1996 2019

Filter
Article
2015
20 Citations (Scopus)

Intensification of Medication Therapy for Cardiorenal Syndrome in Acute Decompensated Heart Failure

Grodin, J. L., Stevens, S. R., de las Fuentes, L., Kiernan, M., Birati, E. Y., Gupta, D., Bart, B. A., Felker, G. M., Chen, H. H., Butler, J., Dávila-Román, V. G., Margulies, K. B., Hernandez, A. F., Anstrom, K. J. & Tang, W. H. W., Apr 5 2015, (Accepted/In press) In : Journal of Cardiac Failure.

Research output: Contribution to journalArticle

Cardio-Renal Syndrome
Heart Failure
Kidney
Diuretics
Weight Loss
184 Citations (Scopus)

Isosorbide mononitrate in heart failure with preserved ejection fraction

Redfield, M. M., Anstrom, K. J., Levine, J. A., Koepp, G. A., Borlaug, B. A., Chen, H. H., LeWinter, M. M., Joseph, S. M., Shah, S. J., Semigran, M. J., Felker, G. M., Cole, R. T., Reeves, G. R., Tedford, R. J., Tang, W. H. W., McNulty, S. E., Velazquez, E. J., Shah, M. R. & Braunwald, E., Dec 10 2015, In : New England Journal of Medicine. 373, 24, p. 2314-2324 11 p.

Research output: Contribution to journalArticle

isosorbide-5-mononitrate
Heart Failure
Placebos
Brain Natriuretic Peptide
Quality of Life
4 Citations (Scopus)

Natriuretic Peptides as a Novel Target in Resistant Hypertension

Patel, P. & Chen, H. H., Mar 1 2015, In : Current Hypertension Reports. 17, 3, p. 18 1 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Hypertension
Antihypertensive Agents
Blood Pressure
Life Style
1 Citation (Scopus)

Response to letter regarding article, Effects of Sildenafil on ventricular and vascular function in heart failure with preserved ejection fraction

Borlaug, B. A., Chen, H. H., Lin, G. D., Redfield, M. M., Lewis, G. D., Semigran, M. J., McNulty, S. E., LeWinter, M., Deswal, A. & Margulies, K. B., May 1 2015, In : Circulation: Heart Failure. 8, 4, p. 840 1 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Surveillance and Care of the Gynecologic Cancer Survivor

Faubion, S. S., Mac Laughlin, K., Long, M. E., Pruthi, S. & Casey, P. M., Nov 1 2015, In : Journal of Women's Health. 24, 11, p. 899-906 8 p.

Research output: Contribution to journalArticle

Neoplasms
Contraception
Fertility
Consensus
Fertility Preservation

Targeting Preclinical Diastolic Dysfunction to Prevent Heart Failure: Contemporary Insights

Wan, S. H. & Chen, H. H., Aug 25 2015, In : Current Cardiovascular Risk Reports. 9, 8, 40.

Research output: Contribution to journalArticle

Heart Failure
Renal Hypertension
Comorbidity
Coronary Artery Disease
Epidemiology
2014
3 Citations (Scopus)

Automated recommendation for cervical cancer screening and surveillance

Wagholikar, K. B., Mac Laughlin, K., Casey, P. M., Kastner, T., Henry, M., Hankey, R., Peters, S. G., Greenes, R., Chute, C. G., Liu, H. D. & Chaudhry, R., Oct 15 2014, In : Cancer Informatics. 13

Research output: Contribution to journalArticle

Clinical Decision Support Systems
Early Detection of Cancer
Uterine Cervical Neoplasms
Guidelines
Decision Trees
13 Citations (Scopus)

Caring for the breast cancer survivor's health and wellbeing

Casey, P. M., Faubion, S. S., Mac Laughlin, K., Long, M. E. & Pruthi, S., Oct 10 2014, In : World Journal of Clinical Oncology. 5, 4, p. 693-704 12 p.

Research output: Contribution to journalArticle

Survivors
Breast Neoplasms
Health
Postcoital Contraception
Continuity of Patient Care
1 Citation (Scopus)

Cell surface protein disulfide isomerase regulates natriuretic peptide generation of cyclic guanosine monophosphate

Pan, S., Chen, H. H., Correia, C., Dai, H., Witt, T. A., Kleppe, L. S., Burnett, J. C. J. & Simari, R. D., Nov 24 2014, In : PLoS One. 9, 11, e112986.

Research output: Contribution to journalArticle

protein disulfide-isomerase
guanosine monophosphate
Protein Disulfide-Isomerases
natriuretic peptides
Natriuretic Peptides
3 Citations (Scopus)
Cohort Effect
Informatics
Patient Compliance
Early Detection of Cancer
Uterine Cervical Neoplasms
8 Citations (Scopus)

Cervical cancer screening in Ghana, West Africa: Prevalence of abnormal cytology and challenges for expanding screening

Handlogten, K. S., Molitor, R. J., Roeker, L. E., Narla, N. P., Bachman, M. J., Quayson, S., Owusu-Afriyie, O., Adjei, E., Ankobea, F., Clayton, A., Roberts, L. R., Mac Laughlin, K. & Ansong, D., Mar 2014, In : International Journal of Gynecological Pathology. 33, 2, p. 197-202 6 p.

Research output: Contribution to journalArticle

Ghana
Western Africa
Early Detection of Cancer
Uterine Cervical Neoplasms
Cell Biology
9 Citations (Scopus)
Guanosine Monophosphate
Physiological Phenomena
Therapeutics
Erectile Dysfunction
Pulmonary Hypertension
3 Citations (Scopus)

Clostridium septicum brain abscesses in a premature neonate

Sadarangani, S. P., Batdorf, R., Buchhalter, L. C., Mrelashvili, A., Banerjee, R., Henry, N. K., Huskins, W. C. & Boyce, T. G., 2014, In : Pediatric Infectious Disease Journal. 33, 5, p. 538-540 3 p.

Research output: Contribution to journalArticle

Clostridium septicum
Brain Abscess
Newborn Infant
Necrotizing Enterocolitis
Premature Infants
3 Citations (Scopus)
Natriuretic Agents
Brain Natriuretic Peptide
Kidney Diseases
Vasodilator Agents
Dopamine
3 Citations (Scopus)

Impact of symptom remission on outpatient visits in depressed primary care patients treated with collaborative care management and usual care

Meunier, M. R., Angstman, K. B., Mac Laughlin, K., Oberhelman, S. S., Rohrer, J. E., Katzelnick, D. J. & Matthews, M. R., Jun 1 2014, In : Population Health Management. 17, 3, p. 180-184 5 p.

Research output: Contribution to journalArticle

Primary Health Care
Outpatients
Odds Ratio
Confidence Intervals
Patient Acceptance of Health Care
1 Citation (Scopus)

Increased adherence to prenatal group B streptococcal screening guidelines through a paired electronic reminder and education intervention

MacLaughlin, K. L., Garrison, G. M., Matthews, M. R., O'Brien, M. L., Westby, E. & Targonski, P. V., Jan 2014, In : Maternal and Child Health Journal. 18, 1, p. 16-21 6 p.

Research output: Contribution to journalArticle

Centers for Disease Control and Prevention (U.S.)
Guidelines
Education
Pregnant Women
Multivariate Analysis
3 Citations (Scopus)

In vitro evaluation of cenderitide-eluting stent I - An antirestenosis and proendothelization approach

Ng, X. W., Huang, Y., Liu, K. L., Lim, S. G., Chen, H. H., Burnett, J. C. J., Boey, Y. C. F. & Venkatraman, S. S., Sep 15 2014, In : Journal of Pharmaceutical Sciences. 103, 11, p. 3631-3640 10 p.

Research output: Contribution to journalArticle

Stents
Cell Proliferation
Smooth Muscle Myocytes
Drug-Eluting Stents
Human Umbilical Vein Endothelial Cells
1 Citation (Scopus)

Is there still a role for low-dose dopamine use in acute heart failure?

Torres-Courchoud, I. & Chen, H. H., 2014, In : Current Opinion in Critical Care. 20, 5, p. 467-471 5 p.

Research output: Contribution to journalArticle

Dopamine
Heart Failure
Placebos
Kidney
Cystatin C
146 Citations (Scopus)

Pre-clinical diastolic dysfunction

Wan, S. H., Vogel, M. W. & Chen, H. H., Feb 11 2014, In : Journal of the American College of Cardiology. 63, 5, p. 407-416 10 p.

Research output: Contribution to journalArticle

Heart Failure
Left Ventricular Dysfunction
Dyspnea
Fatigue
Coronary Artery Disease
Left Ventricular Dysfunction
Stroke Volume
Heart Ventricles
Heart Failure
Exercise
5 Citations (Scopus)

ROSE-AHF and lessons learned

Jain, A. K. & Chen, H. H., 2014, In : Current Heart Failure Reports. 11, 3, p. 260-265 6 p.

Research output: Contribution to journalArticle

Heart Failure
Kidney
Brain Natriuretic Peptide
Dopamine
Research
6 Citations (Scopus)

Should the annual pelvic examination go the way of annual cervical cytology?

Mac Laughlin, K., Faubion, S. S., Long, M. E., Pruthi, S. & Casey, P. M., Jul 1 2014, In : Women's Health. 10, 4, p. 373-384 12 p.

Research output: Contribution to journalArticle

Gynecological Examination
Cell Biology
Early Detection of Cancer
Reproductive Health
Expert Testimony
11 Citations (Scopus)

The course of sleep disturbances in early alcohol recovery: An observational cohort study

Kolla, B. P., Schneekloth, T., Biernacka, J. M., Mansukhani, M., Geske, J., Karpyak, V. M., Hall-Flavin, D., Louikianova, L. & Frye, M. A., Jan 2014, In : American Journal on Addictions. 23, 1, p. 21-26 6 p.

Research output: Contribution to journalArticle

Observational Studies
Sleep
Cohort Studies
Alcohols
Hypnotics and Sedatives
10 Citations (Scopus)

The effects of dose reduction of furosemide on glomerular filtration rate in stable systolic heart failure

McKie, P., Schirger, J. A., Benike, S. L., Harstad, L. K. & Chen, H. H., 2014, In : JACC: Heart Failure. 2, 6, p. 675-677 3 p.

Research output: Contribution to journalArticle

Drug Dose Response Relationship
Systolic Heart Failure
Furosemide
Glomerular Filtration Rate
Diuretics
54 Citations (Scopus)

The prevalence of diabetic cardiomyopathy: A population-based study in Olmsted County, Minnesota

Dandamudi, S., Slusser, J., Mahoney, D. W., Redfield, M. M., Rodeheffer, R. J. & Chen, H. H., 2014, In : Journal of Cardiac Failure. 20, 5, p. 304-309 6 p.

Research output: Contribution to journalArticle

Diabetic Cardiomyopathies
Population
Heart Failure
Left Ventricular Dysfunction
Coronary Disease
2013
9 Citations (Scopus)

Cenderitide-Eluting Film for Potential Cardiac Patch Applications

Ng, X. W., Huang, Y., Chen, H. H., Burnett, J. C. J., Boey, F. Y. C. & Venkatraman, S. S., Jul 4 2013, In : PLoS One. 8, 7, e68346.

Research output: Contribution to journalArticle

Fibroblasts
fibroblasts
natriuretic peptides
peptides
Bioactivity
587 Citations (Scopus)

Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: A randomized clinical trial

Redfield, M. M., Chen, H. H., Borlaug, B. A., Semigran, M. J., Lee, K. L., Lewis, G., LeWinter, M. M., Rouleau, J. L., Bull, D. A., Mann, D. L., Deswal, A., Stevenson, L. W., Givertz Elizabeth O Ofili, M. M., O'Connor, C. M., Felker, G. M., Goldsmith, S. R., Bart, B. A., McNulty, S. E., Ibarra, J. C., Lin, G. D. & 9 others, Oh, J. K., Patel, M. R., Kim, R. J., Tracy, R. P., Velazquez, E. J., Anstrom, K. J., Hernandez, A. F., Mascette, A. M. & Braunwald, E., Mar 27 2013, In : JAMA - Journal of the American Medical Association. 309, 12, p. 1268-1277 10 p.

Research output: Contribution to journalArticle

Type 5 Cyclic Nucleotide Phosphodiesterases
Randomized Controlled Trials
Heart Failure
Placebos
Exercise
18 Citations (Scopus)

Formative evaluation of the accuracy of a clinical decision support system for cervical cancer screening

Wagholikar Dr., K. B., Mac Laughlin, K., Kastner, T. M., Casey, P. M., Henry, M., Greenes, R. A., Liu, H. D. & Chaudhry, R., 2013, In : Journal of the American Medical Informatics Association. 20, 4, p. 749-757 9 p.

Research output: Contribution to journalArticle

Clinical Decision Support Systems
Early Detection of Cancer
Uterine Cervical Neoplasms
Crowdsourcing
Guidelines
20 Citations (Scopus)

Functional aerobic capacity in patients with sleep-disordered breathing

Mansukhani, M., Allison, T. G., Lopez-Jimenez, F., Somers, V. & Caples, S. M., Jun 1 2013, In : American Journal of Cardiology. 111, 11, p. 1650-1654 5 p.

Research output: Contribution to journalArticle

Sleep Apnea Syndromes
Apnea
Body Mass Index
Exercise
Heart Rate
5 Citations (Scopus)
Odds Ratio
Remission
Interrelationship
Enrollment
Predictors
2 Citations (Scopus)

In-Vivo Evaluation of an In Situ Polymer Precipitation Delivery System for a Novel Natriuretic Peptide

Lim, S. G., Venkatraman, S. S., Burnett, J. C. J. & Chen, H. H., Feb 18 2013, In : PLoS One. 8, 2, e52484.

Research output: Contribution to journalArticle

natriuretic peptides
guanosine
Natriuretic Peptides
Cyclic GMP
polymers
257 Citations (Scopus)

Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: The ROSE acute heart failure randomized trial

Chen, H. H., Anstrom, K. J., Givertz, M. M., Stevenson, L. W., Semigran, M. J., Goldsmith, S. R., Bart, B. A., Bull, D. A., Stehlik, J., LeWinter, M. M., Konstam, M. A., Huggins, G. S., Rouleau, J. L., O'Meara, E., Tang, W. H. W., Starling, R. C., Butler, J., Deswal, A., Felker, G. M., O'Connor, C. M. & 14 others, Bonita, R. E., Margulies, K. B., Cappola, T. P., Ofili, E. O., Mann, D. L., Dávila-Román, V. G., McNulty, S. E., Borlaug, B. A., Velazquez, E. J., Lee, K. L., Shah, M. R., Hernandez, A. F., Braunwald, E. & Redfield, M. M., 2013, In : JAMA - Journal of the American Medical Association. 310, 23, p. 2533-2543 11 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Dopamine
Heart Failure
Placebos
Kidney
13 Citations (Scopus)

Patient self-assessment factors predictive of persistent depressive symptoms 6 months after enrollment in collaborative care management

Angstman, K. B., Shippee, N. D., Mac Laughlin, K., Rasmussen, N. H., Wilkinson, J. M., Williams, M. D. & Katzelnick, D. J., Feb 2013, In : Depression and Anxiety. 30, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

Depression
Mood Disorders
Anxiety
Self-Assessment
Major Depressive Disorder
9 Citations (Scopus)
Brain Natriuretic Peptide
Controlled Clinical Trials
Left Ventricular Function
Myocardial Infarction
Placebos
18 Citations (Scopus)

Targeting the kidney in acute heart failure: Can old drugs provide new benefit? Renal optimization strategies evaluation in acute heart failure (ROSE AHF) trial

Chen, H. H., Abou Ezzeddine, O., Anstrom, K. J., Givertz, M. M., Bart, B. A., Felker, G. M., Hernandez, A. F., Lee, K. L., Braunwald, E. & Redfield, M. M., Sep 2013, In : Circulation: Heart Failure. 6, 5, p. 1087-1094 8 p.

Research output: Contribution to journalArticle

Cardiovascular Agents
Natriuretic Peptides
Brain Natriuretic Peptide
Acute Disease
Clinical Protocols
28 Citations (Scopus)

The association between atrial fibrillation and stroke in patients with obstructive sleep apnea: A population-based case-control study

Mansukhani, M., Calvin, A. D., Kolla, B. P., Brown, R. D. J., Lipford, M., Somers, V. & Caples, S. M., Mar 2013, In : Sleep Medicine. 14, 3, p. 243-246 4 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Atrial Fibrillation
Case-Control Studies
Stroke
Population
2012
61 Citations (Scopus)

Biomarkers in acutely decompensated heart failure with preserved or reduced ejection fraction

Bishu, K., Deswal, A., Chen, H. H., Lewinter, M. M., Lewis, G. D., Semigran, M. J., Borlaug, B. A., McNulty, S., Hernandez, A. F., Braunwald, E. & Redfield, M. M., Nov 2012, In : American Heart Journal. 164, 5

Research output: Contribution to journalArticle

Heart Failure
Biomarkers
Renin-Angiotensin System
Natriuretic Peptides
Mineralocorticoid Receptor Antagonists
66 Citations (Scopus)

Cardiorenal rescue study in acute decompensated heart failure: Rationale and design of CARRESS-HF, for the heart failure clinical research network

Bart, B. A., Goldsmith, S. R., Lee, K. L., Redfield, M. M., Felker, G. M., O'Connor, C. M., Chen, H. H., Rouleau, J. L., Givertz, M. M., Semigran, M. J., Mann, D., Deswal, A., Bull, D. A., Lewinter, M. M. & Braunwald, E., Mar 2012, In : Journal of Cardiac Failure. 18, 3, p. 176-182 7 p.

Research output: Contribution to journalArticle

Heart Failure
Research
Kidney
Ultrafiltration
Cardio-Renal Syndrome
38 Citations (Scopus)

CD-NP: A Novel Engineered Dual Guanylyl Cyclase Activator with Anti-Fibrotic Actions in the Heart

Martin, F. L., Sangaralingham, S. J., Huntley, B. K., McKie, P., Ichiki, T., Chen, H. H., Korinek, J., Harders, G. E. & Burnett, J. C. J., Dec 18 2012, In : PLoS One. 7, 12, e52422.

Research output: Contribution to journalArticle

natriuretic peptides
guanylate cyclase
Natriuretic Peptides
Guanylate Cyclase
heart
6 Citations (Scopus)

Chemoprevention of breast cancer

Files, J. A., Stan, D. L., Allen, S. & Pruthi, S., Nov 2012, In : Women's Health. 8, 6, p. 635-646 12 p.

Research output: Contribution to journalArticle

Chemoprevention
Breast Neoplasms
Patient Preference
Biomedical Research
Comorbidity
36 Citations (Scopus)

Clinical decision support with automated text processing for cervical cancer screening

Wagholikar, K. B., Mac Laughlin, K., Henry, M. R., Greenes, R. A., Hankey, R. A., Liu, H. D. & Chaudhry, R. C., Sep 2012, In : Journal of the American Medical Informatics Association. 19, 5, p. 833-839 7 p.

Research output: Contribution to journalArticle

Clinical Decision Support Systems
Early Detection of Cancer
Uterine Cervical Neoplasms
Guidelines
Papanicolaou Test
47 Citations (Scopus)

Experimental mild renal insufficiency mediates early cardiac apoptosis, fibrosis, and diastolic dysfunction: A kidney-heart connection

Martin, F. L., McKie, P., Cataliotti, A., Sangaralingham, S. J., Korinek, J., Huntley, B. K., Oehler, E. A., Harders, G. E., Ichiki, T., Mangiafico, S., Nath, K. A., Redfield, M. M., Chen, H. H. & Burnett, J. C. J., Jan 2012, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 302, 2

Research output: Contribution to journalArticle

Renal Insufficiency
Fibrosis
Apoptosis
Kidney
Brain Natriuretic Peptide
3 Citations (Scopus)

Hormones therapy for management of menopausal breast cancer risk

Files, J. A., Allen, S. & Pruthi, S., Jun 2012, In : Minerva Ginecologica. 64, 3, p. 223-230 8 p.

Research output: Contribution to journalArticle

Hormones
Breast Neoplasms
Therapeutics
Survivors
Women's Health
47 Citations (Scopus)

Human hypertension is characterized by a lack of activation of the antihypertensive cardiac hormones ANP and BNP

MacHeret, F., Heublein, D., Costello-Boerrigter, L. C., Boerrigter, G., McKie, P., Bellavia, D., Mangiafico, S., Ikeda, Y. H., Bailey, K. R., Scott, C. G., Sandberg, S., Chen, H. H., Malatino, L., Redfield, M. M., Rodeheffer, R., Burnett, J. C. J. & Cataliotti, A., Oct 16 2012, In : Journal of the American College of Cardiology. 60, 16, p. 1558-1565 8 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Atrial Natriuretic Factor
Antihypertensive Agents
Hormones
Hypertension
3 Citations (Scopus)

Measurement of left and right ventricular volumes with tomographic equilibrium radionuclide angiocardiography and cardiac MRI

Clements, I. P., Akerem Khan, S. K., Chen, H. H. & Mullan, B. P., May 2012, In : Nuclear Medicine Communications. 33, 5, p. 481-485 5 p.

Research output: Contribution to journalArticle

Gated Blood-Pool Imaging
Stroke Volume
Single-Photon Emission-Computed Tomography
Coronary Thrombosis
Photons
2 Citations (Scopus)

Nocturnal polysomnographic characteristics of pediatric narcolepsy

Rao, S. C., Mansukhani, M., Lloyd, R. M., Slocumb, N. L. & Kotagal, S., Jan 1 2012, In : Sleep and Biological Rhythms. 10, 1, p. 69-71 3 p.

Research output: Contribution to journalArticle

Narcolepsy
Pediatrics
Sleep
Reference Values
Population
68 Citations (Scopus)

Novel protein therapeutics for systolic heart failure: Chronic subcutaneous B-type natriuretic peptide

Chen, H. H., Glockner, J., Schirger, J. A., Cataliotti, A., Redfield, M. M. & Burnett, J. C. J., Dec 4 2012, In : Journal of the American College of Cardiology. 60, 22, p. 2305-2312 8 p.

Research output: Contribution to journalArticle

Systolic Heart Failure
Brain Natriuretic Peptide
Heart Failure
Placebos
Proteins
1 Citation (Scopus)

Outcomes in women age 40 years and older with cytologically benign endometrial cells

Casey, P. M., Gallenberg, M. M., Kastner, T. M., Barrette, B. A., Chantigian, P. D. M., Shuster, L. T., Mac Laughlin, K., Allensworth, S. K. & Weaver, A. L., Nov 2012, In : American Journal of Obstetrics and Gynecology. 207, 5

Research output: Contribution to journalArticle

Hyperplasia
Hemorrhage
Endometrial Hyperplasia
Hysteroscopy
Neoplasms
4 Citations (Scopus)

Patient's weight 6 months after depression treatment is not affected by either clinical remission or enrolment in collaborative care management

Angstman, K. B., Wade, T. W., DeJesus, R. S., MacLaughlin, K. L. & Angstman, G. L., Aug 2012, In : Mental Health in Family Medicine. 10, 1, p. 15-21 7 p.

Research output: Contribution to journalArticle

Depression
Weights and Measures
Weight Loss
Therapeutics
Weight Gain
16 Citations (Scopus)

Patient understanding of the revised USPSTF screening mammogram guidelines: need for development of patient decision aids

Allen, S., Solberg Nes, L., Marnach, M. L., Polga, K., Jenkins, S. M., Files, J. A., Croghan, I. T., Ghosh, K. & Pruthi, S., Oct 10 2012, In : BMC Women's Health. 12, 36.

Research output: Contribution to journalArticle

Decision Support Techniques
Advisory Committees
Guidelines
Mammography
Anxiety