Family Medicine

Research Output 1996 2019

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265 Citations (Scopus)

Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: The ROSE acute heart failure randomized trial

Chen, H. H., Anstrom, K. J., Givertz, M. M., Stevenson, L. W., Semigran, M. J., Goldsmith, S. R., Bart, B. A., Bull, D. A., Stehlik, J., LeWinter, M. M., Konstam, M. A., Huggins, G. S., Rouleau, J. L., O'Meara, E., Tang, W. H. W., Starling, R. C., Butler, J., Deswal, A., Felker, G. M., O'Connor, C. M. & 14 others, Bonita, R. E., Margulies, K. B., Cappola, T. P., Ofili, E. O., Mann, D. L., Dávila-Román, V. G., McNulty, S. E., Borlaug, B. A., Velazquez, E. J., Lee, K. L., Shah, M. R., Hernandez, A. F., Braunwald, E. & Redfield, M. M., 2013, In : JAMA - Journal of the American Medical Association. 310, 23, p. 2533-2543 11 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Dopamine
Heart Failure
Placebos
Kidney
90 Citations (Scopus)
Brain Natriuretic Peptide
Cystatins
Cardiopulmonary Bypass
Placebos
Kidney
41 Citations (Scopus)

Low-dose nesiritide in human anterior myocardial infarction suppresses aldosterone and preserves ventricular function and structure: A proof of concept study

Chen, H. H., Martin, F. L., Gibbons, R. J., Schirger, J. A., Wright, R. S., Schears, R. M., Redfield, M. M., Simari, R. D., Lerman, A., Cataliotti, A. & Burnett, J. C. J., Aug 2009, In : Heart. 95, 16, p. 1315-1319 5 p.

Research output: Contribution to journalArticle

Ventricular Function
Brain Natriuretic Peptide
Aldosterone
Myocardial Infarction
Stroke Volume
45 Citations (Scopus)

Maximizing the natriuretic peptide system in experimental heart failure: Subcutaneous brain natriuretic peptide and acute vasopeptidase inhibition

Chen, H. H., Lainchbury, J. G., Harty, G. J. & Burnett, J. C. J., Feb 26 2002, In : Circulation. 105, 8, p. 999-1003 5 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Neprilysin
41 Citations (Scopus)
Type 5 Cyclic Nucleotide Phosphodiesterases
Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Cyclic GMP
10 Citations (Scopus)

Meaningful conversations in living with and treating chronic conditions: Development of the ICAN discussion aid

Boehmer, K. R., Hargraves, I. G., Allen, S., Matthews, M. R., Maher, C. & Montori, V. M., Sep 23 2016, In : BMC Health Services Research. 16, 1, 514.

Research output: Contribution to journalArticle

Self-Help Groups
Health
Therapeutics
Referral and Consultation
Population
3 Citations (Scopus)

Measurement of left and right ventricular volumes with tomographic equilibrium radionuclide angiocardiography and cardiac MRI

Clements, I. P., Akerem Khan, S. K., Chen, H. H. & Mullan, B. P., May 2012, In : Nuclear Medicine Communications. 33, 5, p. 481-485 5 p.

Research output: Contribution to journalArticle

Gated Blood-Pool Imaging
Stroke Volume
Single-Photon Emission-Computed Tomography
Coronary Thrombosis
Photons
2 Citations (Scopus)

Menopause Management Knowledge in Postgraduate Family Medicine, Internal Medicine, and Obstetrics and Gynecology Residents: A Cross-Sectional Survey

Kling, J. M., Mac Laughlin, K., Schnatz, P. F., Crandall, C. J., Skinner, L. J., Stuenkel, C. A., Kauntiz, A. M., Bitner, D. L., Mara, K., Fohmader Hilsaca, K. S. & Faubion, S. S., Feb 1 2019, In : Mayo Clinic proceedings. 94, 2, p. 242-253 12 p.

Research output: Contribution to journalArticle

Knowledge Management
Internal Medicine
Menopause
Gynecology
Obstetrics

Mortality's wisdom

Ingram, C., Mar 1 2019, In : Families, systems & health : the journal of collaborative family healthcare. 37, 1, 1 p.

Research output: Contribution to journalArticle

Learning
Mortality
57 Citations (Scopus)
Neprilysin
Natriuretic Peptides
Peptide Receptors
Kidney
Protease Inhibitors
4 Citations (Scopus)

Natriuretic Peptides as a Novel Target in Resistant Hypertension

Patel, P. & Chen, H. H., Mar 1 2015, In : Current Hypertension Reports. 17, 3, p. 18 1 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Hypertension
Antihypertensive Agents
Blood Pressure
Life Style
12 Citations (Scopus)
Natriuretic Peptides
Atrial Natriuretic Factor
Cardiac Myocytes
Cardiovascular Diseases
Heart Failure
97 Citations (Scopus)

Natriuretic peptides in the pathophysiology of congestive heart failure

Chen, H. H. & Burnett, J. C. J., 2000, In : Current Cardiology Reports. 2, 3, p. 198-205 8 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Brain Natriuretic Peptide
Atrial Natriuretic Factor
C-Type Natriuretic Peptide
Heart Failure
12 Citations (Scopus)

Nesiritide in acute decompensated heart failure: Current status and future perspectives

Mohammed, S. F., Korinek, J., Chen, H. H., Burnett, J. C. J. & Redfield, M. M., Jun 2008, In : Reviews in Cardiovascular Medicine. 9, 3, p. 151-158 8 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Heart Failure
Mortality
Nitroglycerin
Vasodilator Agents

Neurological Sleep Disorders and Blood Pressure: Current Evidence

Mansukhani, M. P., Covassin, N. & Somers, V. K., Oct 1 2019, In : Hypertension (Dallas, Tex. : 1979). 74, 4, p. 726-732 7 p.

Research output: Contribution to journalArticle

Nervous System Diseases
Blood Pressure
Sleep Bruxism
REM Sleep Behavior Disorder
Cataplexy
83 Citations (Scopus)

Neutral endopeptidase inhibition potentiates the natriuretic actions of adrenomedullin

Lisy, O., Jougasaki, M., Schirger, J. A., Chen, H. H., Barclay, P. T. & Burnett, J. C. J., Sep 1998, In : American Journal of Physiology - Renal Physiology. 275, 3 44-3

Research output: Contribution to journalArticle

Adrenomedullin
Neprilysin
Kidney
Sodium
Disulfides
2 Citations (Scopus)

Nocturnal polysomnographic characteristics of pediatric narcolepsy

Rao, S. C., Mansukhani, M., Lloyd, R. M., Slocumb, N. L. & Kotagal, S., Jan 1 2012, In : Sleep and Biological Rhythms. 10, 1, p. 69-71 3 p.

Research output: Contribution to journalArticle

Narcolepsy
Pediatrics
Sleep
Reference Values
Population
10 Citations (Scopus)

Novel natriuretic peptides: New compounds and new approaches

Vogel, M. W. & Chen, H. H., Mar 2011, In : Current Heart Failure Reports. 8, 1, p. 22-27 6 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Heart Failure
Atrial Natriuretic Factor
Endocrine System
Brain Natriuretic Peptide
68 Citations (Scopus)

Novel protein therapeutics for systolic heart failure: Chronic subcutaneous B-type natriuretic peptide

Chen, H. H., Glockner, J., Schirger, J. A., Cataliotti, A., Redfield, M. M. & Burnett, J. C. J., Dec 4 2012, In : Journal of the American College of Cardiology. 60, 22, p. 2305-2312 8 p.

Research output: Contribution to journalArticle

Systolic Heart Failure
Brain Natriuretic Peptide
Heart Failure
Placebos
Proteins
2 Citations (Scopus)

Nurse-Led Patient-Centered Advance Care Planning in Primary Care

Holland, DI. E., Vanderboom, C. E., Dose, A. M., Ingram, C., Delgado, A., Austin, C. M., Green, M. J. & Levi, B., Aug 1 2017, In : Journal of Hospice and Palliative Nursing. 19, 4, p. 368-375 8 p.

Research output: Contribution to journalArticle

Advance Care Planning
Patient-Centered Care
Primary Health Care
Nurses
Delivery of Health Care
13 Citations (Scopus)

Oral Brain Natriuretic Peptide: A Novel Strategy for Chronic Protein Therapy for Cardiovascular Disease

Cataliotti, A., Chen, H. H., James, K. D. & Burnett, J. C. J., Jan 2007, In : Trends in Cardiovascular Medicine. 17, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Cardiovascular Diseases
Brain
Natriuretic Peptides
Proteins
54 Citations (Scopus)

Oral human brain natriuretic peptide activates cyclic guanosine 3′,5′-monophosphate and decreases mean arterial pressure

Cataliotti, A., Schirger, J. A., Martin, F. L., Chen, H. H., McKie, P., Boerrigter, G., Costello-Boerrigter, L. C., Harty, G., Heublein, D. M., Sandberg, S. M., James, K. D., Miller, M. A., Malkar, N. B., Polowy, K. & Burnett, J. C. J., Aug 9 2005, In : Circulation. 112, 6, p. 836-840 5 p.

Research output: Contribution to journalArticle

Guanosine Monophosphate
Brain Natriuretic Peptide
Arterial Pressure
Oral Administration
Dogs
1 Citation (Scopus)

Outcomes in women age 40 years and older with cytologically benign endometrial cells

Casey, P. M., Gallenberg, M. M., Kastner, T. M., Barrette, B. A., Chantigian, P. D. M., Shuster, L. T., Mac Laughlin, K., Allensworth, S. K. & Weaver, A. L., Nov 2012, In : American Journal of Obstetrics and Gynecology. 207, 5

Research output: Contribution to journalArticle

Hyperplasia
Hemorrhage
Endometrial Hyperplasia
Hysteroscopy
Neoplasms
1 Citation (Scopus)

PAP and cardiovascular events in adults with sleep apnea: Is PAP useful?

Mansukhani, M., Somers, V. & Shafazand, S., Jan 1 2017, In : Journal of Clinical Sleep Medicine. 13, 12, p. 1487-1489 3 p.

Research output: Contribution to journalArticle

Sleep Apnea Syndromes
38 Citations (Scopus)

Pathophysiology of Volume Overload in Acute Heart Failure Syndromes

Chen, H. H. & Schrier, R. W., Dec 2006, In : American Journal of Medicine. 119, 12 SUPPL.

Research output: Contribution to journalArticle

Heart Failure
Pulmonary Wedge Pressure
Arginine Vasopressin
Sympathetic Nervous System
Renin-Angiotensin System
13 Citations (Scopus)

Patient self-assessment factors predictive of persistent depressive symptoms 6 months after enrollment in collaborative care management

Angstman, K. B., Shippee, N. D., Mac Laughlin, K., Rasmussen, N. H., Wilkinson, J. M., Williams, M. D. & Katzelnick, D. J., Feb 2013, In : Depression and Anxiety. 30, 2, p. 143-148 6 p.

Research output: Contribution to journalArticle

Depression
Mood Disorders
Anxiety
Self-Assessment
Major Depressive Disorder
4 Citations (Scopus)

Patient's weight 6 months after depression treatment is not affected by either clinical remission or enrolment in collaborative care management

Angstman, K. B., Wade, T. W., DeJesus, R. S., MacLaughlin, K. L. & Angstman, G. L., Aug 2012, In : Mental Health in Family Medicine. 10, 1, p. 15-21 7 p.

Research output: Contribution to journalArticle

Depression
Weights and Measures
Weight Loss
Therapeutics
Weight Gain
17 Citations (Scopus)

Patient understanding of the revised USPSTF screening mammogram guidelines: need for development of patient decision aids

Allen, S., Solberg Nes, L., Marnach, M. L., Polga, K., Jenkins, S. M., Files, J. A., Croghan, I. T., Ghosh, K. & Pruthi, S., Oct 10 2012, In : BMC Women's Health. 12, 36.

Research output: Contribution to journalArticle

Decision Support Techniques
Advisory Committees
Guidelines
Mammography
Anxiety
79 Citations (Scopus)

Pharmacodynamics of a novel designer natriuretic peptide, CD-NP, in a first-in-human clinical trial in healthy subjects

Lee, C. Y. W., Chen, H. H., Lisy, O., Swan, S., Cannon, C., Lieu, H. D. & Burnett, J. C. J., Jun 2009, In : Journal of Clinical Pharmacology. 49, 6, p. 668-673 6 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Healthy Volunteers
Clinical Trials
C-Type Natriuretic Peptide
Hypotension
25 Citations (Scopus)

Pharmacological treatment of insomnia in alcohol recovery: A systematic review

Kolla, B. P., Mansukhani, M. & Schneekloth, T., Sep 1 2011, In : Alcohol and Alcoholism. 46, 5, p. 578-585 8 p., agr073.

Research output: Contribution to journalArticle

Open Access
Sleep Initiation and Maintenance Disorders
Sleep
Alcohols
Pharmacology
Trazodone
Open Access
Hypertensive Encephalopathy
Posterior Leukoencephalopathy Syndrome
Monoamine Oxidase Inhibitors
Blood Pressure
Eclampsia
156 Citations (Scopus)

Pre-clinical diastolic dysfunction

Wan, S. H., Vogel, M. W. & Chen, H. H., Feb 11 2014, In : Journal of the American College of Cardiology. 63, 5, p. 407-416 10 p.

Research output: Contribution to journalArticle

Heart Failure
Left Ventricular Dysfunction
Dyspnea
Fatigue
Coronary Artery Disease
12 Citations (Scopus)

Predictors of patient comfort and adherence with less frequent cervical cancer screening

MacLaughlin, K. L., Angstman, K. B., Flynn, P. M., Schmit, J. R., Weaver, A. L. & Shuster, L. T., 2011, In : Quality in Primary Care. 19, 6, p. 355-363 9 p.

Research output: Contribution to journalArticle

Patient Compliance
Early Detection of Cancer
Uterine Cervical Neoplasms
Papanicolaou Test
Patient Comfort
104 Citations (Scopus)

Presence of Dendroaspis natriuretic peptide-like immunoreactivity in human plasma and its increase during human heart failure

Schirger, J. A., Heublein, D. M., Chen, H. H., Lisy, O., Jougasaki, M., Wennberg, P. W. & Burnett, J. C. J., 1999, In : Mayo Clinic Proceedings. 74, 2, p. 126-130 5 p.

Research output: Contribution to journalArticle

Heart Failure
Natriuretic Peptides
Myocardium
C-Type Natriuretic Peptide
Dendroaspis natriuretic peptide
2 Citations (Scopus)

Prevalence and Correlates of Hypersomnolence Symptoms in U.S. Teens

Kolla, B. P., He, J. P., Mansukhani, M., Kotagal, S., Frye, M. A. & Merikangas, K. R., Jan 1 2019, In : Journal of the American Academy of Child and Adolescent Psychiatry.

Research output: Contribution to journalArticle

Disorders of Excessive Somnolence
Sleep
Sleep Initiation and Maintenance Disorders
Odds Ratio
Mental Disorders
56 Citations (Scopus)

Progression of preclinical diastolic dysfunction to the development of symptoms

Correa De Sa, D. D., Hodge, D. O., Slusser, J. P., Redfield, M. M., Simari, R. D., Burnett, J. C. J. & Chen, H. H., Apr 2010, In : Heart. 96, 7, p. 528-532 5 p.

Research output: Contribution to journalArticle

Heart Failure
Dyspnea
Hypertension
Fatigue
Echocardiography

Pulmonary Embolism While on Aspirin for Venous Thromboembolism Prophylaxis After Total Knee Arthroplasty

Roman, F., Allen, J. S., Wurm, H. C. & Mac Laughlin, K., Aug 1 2018, In : Journal of Primary Care and Community Health. 9

Research output: Contribution to journalArticle

Open Access
Knee Replacement Arthroplasties
Venous Thromboembolism
Pulmonary Embolism
Aspirin
Organizations
10 Citations (Scopus)
Brain Natriuretic Peptide
Controlled Clinical Trials
Left Ventricular Function
Myocardial Infarction
Placebos
94 Citations (Scopus)

Renal actions of synthetic Dendroaspis natriuretic peptide

Lisy, O., Jougasaki, M., Heublein, D. M., Schirger, J. A., Chen, H. H., Wennberg, P. W. & Burnett, J. C. J., 1999, In : Kidney International. 56, 2, p. 502-508 7 p.

Research output: Contribution to journalArticle

Kidney
Myocardium
Canidae
Elapidae
Brain Natriuretic Peptide

Renal and humoral pathophysiological actions of angiotensin II in congestive heart failure

Mirzoyev, Z., Anavekar, N. S. & Chen, H. H., Feb 2005, In : Drugs of Today. 41, 2, p. 129-139 11 p.

Research output: Contribution to journalArticle

Angiotensins
Angiotensin II
Heart Failure
Renin-Angiotensin System
Kidney
58 Citations (Scopus)

Renal response to acute neutral endopeptidase inhibition in mild and severe experimental heart failure

Chen, H. H., Schirger, J. A., Chau, W. L., Jougasaki, M., Lisy, O., Redfield, M. M., Barclay, P. T. & Burnett, J. C. J., Dec 14 1999, In : Circulation. 100, 24, p. 2443-2448 6 p.

Research output: Contribution to journalArticle

Neprilysin
Heart Failure
Kidney
Atrial Natriuretic Factor
Sodium
Left Ventricular Dysfunction
Stroke Volume
Heart Ventricles
Heart Failure
Exercise
1 Citation (Scopus)

Response to letter regarding article, Effects of Sildenafil on ventricular and vascular function in heart failure with preserved ejection fraction

Borlaug, B. A., Chen, H. H., Lin, G. D., Redfield, M. M., Lewis, G. D., Semigran, M. J., McNulty, S. E., LeWinter, M., Deswal, A. & Margulies, K. B., May 1 2015, In : Circulation: Heart Failure. 8, 4, p. 840 1 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Risks associated with use of stimulant medications in patients with obstructive sleep apnea and cardiomyopathy: a case-control study

Mansukhani, M., Kolla, B. P. & Park, J. G., Apr 1 2017, In : Sleep Medicine. 32, p. 171-175 5 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Cardiomyopathies
Implantable Defibrillators
Case-Control Studies
Mortality
4 Citations (Scopus)
Natriuretic Peptides
Heart Failure
Peptidyl-Dipeptidase A
Neprilysin
Peptide Receptors
5 Citations (Scopus)

ROSE-AHF and lessons learned

Jain, A. K. & Chen, H. H., 2014, In : Current Heart Failure Reports. 11, 3, p. 260-265 6 p.

Research output: Contribution to journalArticle

Heart Failure
Kidney
Brain Natriuretic Peptide
Dopamine
Research

Severe sleep apnea resistant to all treatments

Colaco, B., Mansukhani, M. & Kolla, B. P., May 1 2017, In : Sleep Medicine. 33, p. 160-164 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Should the annual pelvic examination go the way of annual cervical cytology?

Mac Laughlin, K., Faubion, S. S., Long, M. E., Pruthi, S. & Casey, P. M., Jul 1 2014, In : Women's Health. 10, 4, p. 373-384 12 p.

Research output: Contribution to journalArticle

Gynecological Examination
Cell Biology
Early Detection of Cancer
Reproductive Health
Expert Testimony
63 Citations (Scopus)

Sleep deprivation in resident physicians, work hour limitations, and related outcomes: A systematic review of the literature

Mansukhani, M., Kolla, B. P., Surani, S., Varon, J. & Ramar, K., Jul 1 2012, In : Postgraduate medicine. 124, 4, p. 241-249 9 p.

Research output: Contribution to journalArticle

Sleep Deprivation
Physicians
Sleep
Patient Care
Graduate Medical Education

Sleep Disturbances in a Patient With Bipolar Disorder

Foroughi, M., Kolla, B. P., Saeidifard, F., Altchuler, S. I. & Mansukhani, M., Jun 14 2018, In : The primary care companion for CNS disorders. 20, 3

Research output: Contribution to journalArticle

Bipolar Disorder
Sleep