Family Medicine

Research Output 1996 2019

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1996

68-Year-old man with anemia and renal failure

Chen, H. H., Shields, R. C. & Bardsley, W. T., 1996, In : Mayo Clinic Proceedings. 71, 2, p. 197-200 4 p.

Research output: Contribution to journalArticle

Renal Insufficiency
Anemia
1998
162 Citations (Scopus)
C-Type Natriuretic Peptide
Natriuretic Peptides
Atrial Natriuretic Factor
Vascular Smooth Muscle
Smooth Muscle Myocytes
81 Citations (Scopus)

Neutral endopeptidase inhibition potentiates the natriuretic actions of adrenomedullin

Lisy, O., Jougasaki, M., Schirger, J. A., Chen, H. H., Barclay, P. T. & Burnett, J. C. J., Sep 1998, In : American Journal of Physiology - Renal Physiology. 275, 3 44-3

Research output: Contribution to journalArticle

Adrenomedullin
Neprilysin
Kidney
Sodium
Disulfides
1999
54 Citations (Scopus)

Effect of brinzolamide and dorzolamide on aqueous humor flow in human eyes

Ingram, C. & Brubaker, R. F., Sep 1 1999, In : American journal of ophthalmology. 128, 3, p. 292-296 5 p.

Research output: Contribution to journalArticle

dorzolamide
Aqueous Humor
Intraocular Pressure
Fluorophotometry
Carbonic Anhydrase Inhibitors
104 Citations (Scopus)

Presence of Dendroaspis natriuretic peptide-like immunoreactivity in human plasma and its increase during human heart failure

Schirger, J. A., Heublein, D. M., Chen, H. H., Lisy, O., Jougasaki, M., Wennberg, P. W. & Burnett, J. C. J., 1999, In : Mayo Clinic Proceedings. 74, 2, p. 126-130 5 p.

Research output: Contribution to journalArticle

Heart Failure
Natriuretic Peptides
Myocardium
C-Type Natriuretic Peptide
Dendroaspis natriuretic peptide
94 Citations (Scopus)

Renal actions of synthetic Dendroaspis natriuretic peptide

Lisy, O., Jougasaki, M., Heublein, D. M., Schirger, J. A., Chen, H. H., Wennberg, P. W. & Burnett, J. C. J., 1999, In : Kidney International. 56, 2, p. 502-508 7 p.

Research output: Contribution to journalArticle

Kidney
Myocardium
Canidae
Elapidae
Brain Natriuretic Peptide
57 Citations (Scopus)

Renal response to acute neutral endopeptidase inhibition in mild and severe experimental heart failure

Chen, H. H., Schirger, J. A., Chau, W. L., Jougasaki, M., Lisy, O., Redfield, M. M., Barclay, P. T. & Burnett, J. C. J., Dec 14 1999, In : Circulation. 100, 24, p. 2443-2448 6 p.

Research output: Contribution to journalArticle

Neprilysin
Heart Failure
Kidney
Atrial Natriuretic Factor
Sodium
138 Citations (Scopus)
Natriuretic Peptides
Heart Failure
C-Type Natriuretic Peptide
Brain Natriuretic Peptide
Atrial Natriuretic Factor
2000
18 Citations (Scopus)

Comparison of the efficacy of betaxolol-brinzolamide and timolol- dorzolamide as suppressors of aqueous humor flow in human subjects

Brubaker, R. F., Ingram, C., Schoff, E. O. & Nau, C. B., Feb 1 2000, In : Ophthalmology. 107, 2, p. 283-287 5 p.

Research output: Contribution to journalArticle

dorzolamide
Betaxolol
Timolol
Aqueous Humor
Intraocular Pressure
97 Citations (Scopus)

Natriuretic peptides in the pathophysiology of congestive heart failure

Chen, H. H. & Burnett, J. C. J., 2000, In : Current Cardiology Reports. 2, 3, p. 198-205 8 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Brain Natriuretic Peptide
Atrial Natriuretic Factor
C-Type Natriuretic Peptide
Heart Failure
63 Citations (Scopus)

Subcutaneous administration of brain natriuretic peptide in experimental heart failure

Chen, H. H., Grantham, J. A., Schirger, J. A., Jougasaki, M., Redfield, M. M. & Burnett, J. C. J., Nov 1 2000, In : Journal of the American College of Cardiology. 36, 5, p. 1706-1712 7 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Heart Failure
Pulmonary Wedge Pressure
Renal Circulation
Cyclic GMP
7 Citations (Scopus)
Atrial Natriuretic Factor
Heart Failure
Glyburide
Adenosine Triphosphate
Natriuresis
51 Citations (Scopus)

Vascular actions of brain natriuretic peptide: Modulation by atherosclerosis and neutral endopeptidase inhibition

Schirger, J. A., Grantham, J. A., Kullo, I. J., Jougasaki, M., Wennberg, P. W., Chen, H. H., Lisy, O., Miller, V. M., Simari, R. D. & Burnett, J. C. J., Mar 1 2000, In : Journal of the American College of Cardiology. 35, 3, p. 796-801 6 p.

Research output: Contribution to journalArticle

Neprilysin
Brain Natriuretic Peptide
Blood Vessels
Atherosclerosis
Vascular Smooth Muscle
2001
47 Citations (Scopus)

Endogenous natriuretic peptides participate in renal and humoral actions of acute vasopeptidase inhibition in experimental mild heart failure

Chen, H. H., Lainchbury, J. G., Matsuda, Y., Harty, G. J. & Burnett, J. C. J., 2001, In : Hypertension. 38, 2, p. 187-191 5 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Atrial Natriuretic Factor
Brain Natriuretic Peptide
Heart Failure
Kidney
4 Citations (Scopus)
Natriuretic Peptides
Heart Failure
Peptidyl-Dipeptidase A
Neprilysin
Peptide Receptors
2002
232 Citations (Scopus)

Brain natriuretic peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases

Tsuruda, T., Boerrigter, G., Huntley, B. K., Noser, J. A., Cataliotti, A., Costello-Boerrigter, L. C., Chen, H. H. & Burnett, J. C. J., Dec 2002, In : Circulation Research. 91, 12, p. 1127-1134 8 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Matrix Metalloproteinases
Fibroblasts
Matrix Metalloproteinase 2
Cyclic GMP-Dependent Protein Kinases
73 Citations (Scopus)

Cardiotrophin-1 stimulation of cardiac fibroblast growth: Roles for glycoprotein 130/leukemia inhibitory factor receptor and the endothelin type A receptor

Tsuruda, T., Jougasaki, M., Boerrigter, G., Huntley, B. K., Chen, H. H., D'Assoro, A., Lee, S. C., Larsen, A. M., Cataliotti, A. & Burnett, J. C. J., Feb 8 2002, In : Circulation Research. 90, 2, p. 128-134 7 p.

Research output: Contribution to journalArticle

OSM-LIF Receptors
Endothelin A Receptors
Glycoproteins
Fibroblasts
Growth
40 Citations (Scopus)

Differential actions of vasopeptidase inhibition versus angiotensin-converting enzyme inhibition on diuretic therapy in experimental congestive heart failure

Cataliotti, A., Boerrigter, G., Chen, H. H., Jougasaki, M., Costello, L. C., Tsuruda, T., Lee, S. C., Malatino, L. S. & Burnett, J. C. J., Feb 5 2002, In : Circulation. 105, 5, p. 639-644 6 p.

Research output: Contribution to journalArticle

Investigational Therapies
Peptidyl-Dipeptidase A
Diuretics
Heart Failure
Aldosterone
44 Citations (Scopus)

Maximizing the natriuretic peptide system in experimental heart failure: Subcutaneous brain natriuretic peptide and acute vasopeptidase inhibition

Chen, H. H., Lainchbury, J. G., Harty, G. J. & Burnett, J. C. J., Feb 26 2002, In : Circulation. 105, 8, p. 999-1003 5 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Neprilysin
56 Citations (Scopus)
Neprilysin
Natriuretic Peptides
Peptide Receptors
Kidney
Protease Inhibitors
2003
25 Citations (Scopus)
Angiotensin Type 1 Receptor
Angiotensin Receptors
Diuretics
Glomerular Filtration Rate
Losartan
95 Citations (Scopus)

Immune-mediated tumor regression induced by CpG-containing oligodeoxynucleotides

Baines, J. & Celis, E., Jul 1 2003, In : Clinical Cancer Research. 9, 7, p. 2693-2700 8 p.

Research output: Contribution to journalArticle

Oligodeoxyribonucleotides
T-Lymphocytes
Neoplasms
Carcinoma
Histocompatibility Antigens Class I
15 Citations (Scopus)

Leukemia inhibitory factor is augmented in the heart in experimental heart failure

Jougasaki, M., Leskinen, H., Larsen, A. M., Cataliotti, A., Chen, H. H. & Burnett, J. C. J., Mar 2003, In : European Journal of Heart Failure. 5, 2, p. 137-145 9 p.

Research output: Contribution to journalArticle

Leukemia Inhibitory Factor
Heart Failure
Messenger RNA
Heart Atria
Canidae
56 Citations (Scopus)
Brain Natriuretic Peptide
Heart Failure
Confounding Factors (Epidemiology)
Triage
United States Food and Drug Administration
2004

76-Year-old woman with chest pain

Krajicek, B. J. & Chen, H. H., 2004, In : Mayo Clinic Proceedings. 79, 11, p. 1435-1438 4 p.

Research output: Contribution to journalArticle

Chest Pain
80 Citations (Scopus)

Brain Natriuretic Peptide Enhances Renal Actions of Furosemide and Suppresses Furosemide-Induced Aldosterone Activation in Experimental Heart Failure

Cataliotti, A., Boerrigter, G., Costello-Boerrigter, L. C., Schirger, J. A., Tsuruda, T., Heublein, D. M., Chen, H. H., Malatino, L. S. & Burnett, J. C. J., Apr 6 2004, In : Circulation. 109, 13, p. 1680-1685 6 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Furosemide
Aldosterone
Heart Failure
Kidney
26 Citations (Scopus)

Endothelin A Receptor Antagonism in Experimental Congestive Heart Failure Results in Augmentation of the Renin-Angiotensin System and Sustained Sodium Retention

Schirger, J. A., Chen, H. H., Jougasaki, M., Lisy, O., Boerrigter, G., Cataliotti, A. & Burnett, J. C. J., Jan 20 2004, In : Circulation. 109, 2, p. 249-254 6 p.

Research output: Contribution to journalArticle

Endothelin A Receptors
Renin-Angiotensin System
Heart Failure
Sodium
Endothelin-1
56 Citations (Scopus)

Subcutaneous administration of the cardiac hormone BNP in symptomatic human heart failure

Chen, H. H., Redfield, M. M., Nordstrom, L. J., Horton, D. P. & Burnett, J. C. J., Apr 2004, In : Journal of Cardiac Failure. 10, 2, p. 115-119 5 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Heart Failure
Hormones
Cyclic GMP
Natriuresis
2005
129 Citations (Scopus)

B-type natriuretic peptide in organic mitral regurgitation: Determinants and impact on outcome

Detaint, D., Messika-Zeitoun, D., Avierinos, J. F., Scott, C., Chen, H. H., Burnett, J. C. J. & Sarano, M. E., May 10 2005, In : Circulation. 111, 18, p. 2391-2397 7 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Mitral Valve Insufficiency
Multivariate Analysis
Heart Failure
Ventricular Remodeling
17 Citations (Scopus)

Consensus-degenerate hybrid oligonucleotide primers (CODEHOP) for the detection of novel papillomaviruses and their application to esophageal and tonsillar carcinomas

Baines, J., McGovern, R. M., Persing, D. & Gostout, B. S., Jan 1 2005, In : Journal of Virological Methods. 123, 1, p. 81-87 7 p.

Research output: Contribution to journalArticle

DNA Primers
Carcinoma
Neoplasms
Conserved Sequence
Esophagus
33 Citations (Scopus)
Brain Natriuretic Peptide
Atrial Natriuretic Factor
Heart Failure
Kidney
Natriuretic Peptides
54 Citations (Scopus)

Oral human brain natriuretic peptide activates cyclic guanosine 3′,5′-monophosphate and decreases mean arterial pressure

Cataliotti, A., Schirger, J. A., Martin, F. L., Chen, H. H., McKie, P., Boerrigter, G., Costello-Boerrigter, L. C., Harty, G., Heublein, D. M., Sandberg, S. M., James, K. D., Miller, M. A., Malkar, N. B., Polowy, K. & Burnett, J. C. J., Aug 9 2005, In : Circulation. 112, 6, p. 836-840 5 p.

Research output: Contribution to journalArticle

Guanosine Monophosphate
Brain Natriuretic Peptide
Arterial Pressure
Oral Administration
Dogs

Renal and humoral pathophysiological actions of angiotensin II in congestive heart failure

Mirzoyev, Z., Anavekar, N. S. & Chen, H. H., Feb 2005, In : Drugs of Today. 41, 2, p. 129-139 11 p.

Research output: Contribution to journalArticle

Angiotensins
Angiotensin II
Heart Failure
Renin-Angiotensin System
Kidney
2006
30 Citations (Scopus)

Association of B-type natriuretic peptide activation to left ventricular end-systolic remodeling in organic and functional mitral regurgitation

Detaint, D., Messika-Zeitoun, D., Chen, H. H., Rossi, A., Avierinos, J. F., Scott, C., Burnett, J. C. J. & Sarano, M. E., Apr 1 2006, In : American Journal of Cardiology. 97, 7, p. 1029-1034 6 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Mitral Valve Insufficiency
Biomarkers
Ventricular Remodeling
Doppler Echocardiography
22 Citations (Scopus)
Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Snake Venoms
C-Type Natriuretic Peptide
12 Citations (Scopus)
Natriuretic Peptides
Brain Natriuretic Peptide
Coronary Artery Disease
Exercise
Atrial Natriuretic Factor
15 Citations (Scopus)
Heart Failure
Dogs
Peptides
Second Messenger Systems
Hemodynamics
42 Citations (Scopus)

Lack of activation of molecular forms of the BNP system in human grade 1 hypertension and relationship to cardiac hypertrophy

Belluardo, P., Cataliotti, A., Bonaiuto, L., Giuffré, E., Maugeri, E., Noto, P., Orlando, G., Raspa, G., Piazza, B., Babuin, L., Chen, H. H., Martin, F. L., McKie, P., Heublein, D. M., Burnett, J. C. J. & Malatino, L. S., 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 291, 4

Research output: Contribution to journalArticle

Cardiomegaly
Hypertension
pro-brain natriuretic peptide (1-76)
Brain Natriuretic Peptide
Left Ventricular Hypertrophy
39 Citations (Scopus)
Type 5 Cyclic Nucleotide Phosphodiesterases
Natriuretic Peptides
Brain Natriuretic Peptide
Heart Failure
Cyclic GMP
12 Citations (Scopus)
Natriuretic Peptides
Atrial Natriuretic Factor
Cardiac Myocytes
Cardiovascular Diseases
Heart Failure
38 Citations (Scopus)

Pathophysiology of Volume Overload in Acute Heart Failure Syndromes

Chen, H. H. & Schrier, R. W., Dec 2006, In : American Journal of Medicine. 119, 12 SUPPL.

Research output: Contribution to journalArticle

Heart Failure
Pulmonary Wedge Pressure
Arginine Vasopressin
Sympathetic Nervous System
Renin-Angiotensin System
8 Citations (Scopus)

Therapeutic Potential for Existing and Novel Forms of Natriuretic Peptides

Chen, H. H. & Burnett, J. C. J., Jul 2006, In : Heart Failure Clinics. 2, 3, p. 365-373 9 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Heart Failure
Hormones
Peptides
Therapeutics
2007
8 Citations (Scopus)
Heart Failure
Kidney
Natriuretic Peptides
Glomerular Filtration Rate
omega-N-Methylarginine
55 Citations (Scopus)

Heart Failure. A State of Brain Natriuretic Peptide Deficiency or Resistance or Both!

Chen, H. H., Mar 13 2007, In : Journal of the American College of Cardiology. 49, 10, p. 1089-1091 3 p.

Research output: Contribution to journalArticle

Animal Disease Models
Phosphodiesterase Inhibitors
Brain Natriuretic Peptide
Cardiac Output
Reference Values
90 Citations (Scopus)
Brain Natriuretic Peptide
Cystatins
Cardiopulmonary Bypass
Placebos
Kidney
13 Citations (Scopus)

Oral Brain Natriuretic Peptide: A Novel Strategy for Chronic Protein Therapy for Cardiovascular Disease

Cataliotti, A., Chen, H. H., James, K. D. & Burnett, J. C. J., Jan 2007, In : Trends in Cardiovascular Medicine. 17, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Cardiovascular Diseases
Brain
Natriuretic Peptides
Proteins
18 Citations (Scopus)

Usefulness of Brain Natriuretic Peptide Levels in the Clinical Evaluation of Patients With Hypertrophic Cardiomyopathy

Binder, J., Ommen, S. R., Chen, H. H., Ackerman, M. J., Tajik, A. J. & Jaffe, A. S., Aug 15 2007, In : American Journal of Cardiology. 100, 4, p. 712-714 3 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Hypertrophic Cardiomyopathy
Diastolic Heart Failure
Blood Pressure
Left Ventricular Dysfunction
2008
4 Citations (Scopus)

B-Type Natriuretic Peptide: Beyond a Diagnostic

Martin, F. L., Chen, H. H., Cataliotti, A. & Burnett, J. C. J., Oct 2008, In : Heart Failure Clinics. 4, 4, p. 449-454 6 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Second Messenger Systems
Heart Failure
Natriuretic Peptides
Cyclic GMP
25 Citations (Scopus)

Chronic actions of a novel oral B-type natriuretic peptide conjugate in normal dogs and acute actions in angiotensin II-mediated hypertension

Cataliotti, A., Chen, H. H., Schirger, J. A., Martin, F. L., Boerrigter, G., Costello-Boerrigter, L. C., James, K. D., Polowy, K., Miller, M. A., Malkar, N. B., Bailey, K. R. & Burnett, J. C. J., Oct 21 2008, In : Circulation. 118, 17, p. 1729-1736 8 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Angiotensin II
Dogs
Hypertension
Blood Pressure
12 Citations (Scopus)

Nesiritide in acute decompensated heart failure: Current status and future perspectives

Mohammed, S. F., Korinek, J., Chen, H. H., Burnett, J. C. J. & Redfield, M. M., Jun 2008, In : Reviews in Cardiovascular Medicine. 9, 3, p. 151-158 8 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Heart Failure
Mortality
Nitroglycerin
Vasodilator Agents