Biomedical Statistics and Informatics

Research output

Research output per year 1991 2011 2012 2013 2014 2015 2017 2018 2022

• 354 Article
• 32 Conference contribution
• 13 Conference article
• 10 Comment/debate
• 29 More
  • 10 Review article
  • 8 Letter
  • 7 Editorial
  • 3 Chapter
  • 1 Book

Research output per year

Research output per year

Search results

• 2017

  MTCTScan: A comprehensive platform for annotation and prioritization of mutations affecting drug sensitivity in cancers

  Li, M. J., Yao, H., Huang, D., Liu, H., Liu, Z., Xu, H., Qin, Y., Prinz, J., Xia, W., Wang, P., Yan, B., Tran, N. L., Kocher, J. P., Sham, P. C. & Wang, J., Jul 3 2017, In: Nucleic acids research. 45, W1, p. W215-W221

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mutation 100%
  • Pharmaceutical Preparations 73%
  • Neoplasms 57%
  • Precision Medicine 12%
  • Therapeutics 9%
  6 Scopus citations

• Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix

  Heim, J. B., Squirewell, E. J., Neu, A., Zocher, G., Sominidi-Damodaran, S., Wyles, S. P., Nikolova, E., Behrendt, N., Saunte, D. M., Lock-Andersen, J., Gaonkar, K. S., Yan, H., Sarkaria, J. N., Krendel, M., Van Deursen, J., Sprangers, R., Stehle, T., Böttcher, R. T., Lee, J. H., Ordog, T. & 1 others, Meves, A., Apr 11 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 15, p. 3933-3938 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Focal Adhesion Protein-Tyrosine Kinases 100%
  • Myosins 87%
  • Proline 85%
  • Fibronectins 78%
  • Phosphotransferases 31%
  10 Scopus citations

• Patient-reported (EORTC QLQ-CIPN20) versus physician-reported (CTCAE) quantification of oxaliplatin- and paclitaxel/carboplatin-induced peripheral neuropathy in NCCTG/Alliance clinical trials

  Le-Rademacher, J., Kanwar, R., Seisler, D., Pachman, D. R., Qin, R., Abyzov, A., Ruddy, K. J., Banck, M. S., Lavoie Smith, E. M., Dorsey, S. G., Aaronson, N. K., Sloan, J., Loprinzi, C. L. & Beutler, A. S., Nov 1 2017, In: Supportive Care in Cancer. 25, 11, p. 3537-3544 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxaliplatin 100%
  • Carboplatin 95%
  • Peripheral Nervous System Diseases 89%
  • Paclitaxel 85%
  • Terminology 85%
  26 Scopus citations

• Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL

  Ding, W., LaPlant, B. R., Call, T. G., Parikh, S. A., Leis, J. F., He, R., Shanafelt, T. D., Sinha, S., Le-Rademacher, J., Feldman, A. L., Habermann, T. M., Witzig, T. E., Wiseman, G. A., Lin, Y., Asmus, E., Nowakowski, G. S., Conte, M. J., Bowen, D. A., Aitken, C. N., Van Dyke, D. L. & 15 others, Greipp, P. T., Liu, X., Wu, X., Zhang, H., Secreto, C. R., Tian, S., Braggio, E., Wellik, L. E., Micallef, I., Viswanatha, D. S., Yan, H., Chanan-Khan, A. A., Kay, N. E., Dong, H. & Ansell, S. M., Jun 29 2017, In: Blood. 129, 26, p. 3419-3427 9 p.

  Research output: Contribution to journal › Article › peer-review

  • pembrolizumab 100%
  • B-Cell Chronic Lymphocytic Leukemia 75%
  • Ibrutinib 56%
  • Chemical Transformation 44%
  • PCI 32765 32%
  185 Scopus citations

• RNA sequence analysis of rat acute experimental pancreatitis with and without fatty liver: A gene expression profiling comparative study

  Wang, Q., Yan, H., Wang, G., Qiu, Z., Bai, B., Wang, S., Yu, P., Feng, Q., Zhao, Q., He, X. & Liu, C., Dec 1 2017, In: Scientific reports. 7, 1, 734.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA Sequence Analysis 100%
  • Fatty Liver 95%
  • Gene Expression Profiling 92%
  • Pancreatitis 86%
  • Peroxisome Proliferator-Activated Receptors 30%

• Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer

  Goetz, M. P., Kalari, K. R., Suman, V. J., Moyer, A. M., Yu, J., Visscher, D. W., Dockter, T. J., Vedell, P. T., Sinnwell, J. P., Tang, X., Thompson, K. J., McLaughlin, S. A., Moreno-Aspitia, A., Copland, J. A., Northfelt, D. W., Gray, R. J., Hunt, K., Conners, A., Weinshilboum, R., Wang, L. & 35 others, Boughey, J. C., Goetz, M. P., Kalari, K. R., Suman, V. J., Moyer, A. M., Yu, J., Visscher, D. W., Dockter, T. J., Vedell, P. T., Sinnwell, J. P., Tang, X., Thompson, K. J., Barman, P., Mahoney, D. W., Carlson, E., Hart, S. N., Yin, P., Qin, B., Felten, S. J., McLaughlin, S. A., Copland, J. A., Northfelt, D. W., Gray, R. J., Hunt, K., Conners, A. L., Sicotte, H., Eckel-Passow, J. E., Kocher, J. P., Ingle, J. N., Ellingson, M. S., McDonough, M., Wieben, E. D., Weinshilboum, R., Wang, L. & Boughey, J. C., Jul 1 2017, In: Journal of the National Cancer Institute. 109, 7

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neoadjuvant Therapy 100%
  • Heterografts 77%
  • Breast Neoplasms 55%
  • Drug Therapy 35%
  • Androgen Receptors 27%
  32 Scopus citations

• UClncR: Ultrafast and comprehensive long non-coding RNA detection from RNA-seq

  Sun, Z., Nair, A., Chen, X., Prodduturi, N., Wang, J. & Kocher, J. P., Dec 1 2017, In: Scientific reports. 7, 1, 14196.

  Research output: Contribution to journal › Article › peer-review

  • RNA-Seq 100%
  • Long Noncoding RNA 92%
  • Genes 7%
  • Datasets 7%
  • Research Personnel 6%
  19 Scopus citations
• 2016

  An analytical workflow for accurate variant discovery in highly divergent regions

  Tian, S., Yan, H., Neuhauser, C. & Slager, S. L., Sep 2 2016, In: BMC genomics. 17, 1, 703.

  Research output: Contribution to journal › Article › peer-review

  • Workflow 100%
  • HLA Antigens 93%
  • Chromosomes, Human, Pair 6 34%
  • Single Nucleotide Polymorphism 32%
  • Exome 31%
  9 Scopus citations

• Circular RNAs and their associations with breast cancer subtypes

  Nair, A. A., Niu, N., Tang, X., Thompson, K. J., Wang, L., Kocher, J. P., Subramanian, S. & Kalari, K. R., 2016, In: Oncotarget. 7, 49, p. 80967-80979 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Circular RNAs 100%
  • Breast Neoplasms 46%
  • Workflow 14%
  • Atlases 14%
  • Neoplasms 10%
  106 Scopus citations

• Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505)

  Pachman, D. R., Qin, R., Seisler, D., Smith, E. M. L., Kaggal, S., Novotny, P., Ruddy, K. J., Lafky, J. M., Ta, L. E., Beutler, A. S., Wagner-Johnston, N. D., Staff, N. P., Grothey, A., Dougherty, P. M., Cavaletti, G. & Loprinzi, C. L., Dec 1 2016, In: Supportive Care in Cancer. 24, 12, p. 5059-5068 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxaliplatin 100%
  • Paclitaxel 85%
  • Drug Therapy 35%
  • Foot 20%
  • Hand 18%
  33 Scopus citations

• CpGFilter: Model-based CpG probe filtering with replicates for epigenome-wide association studies

  Chen, J., Just, A. C., Schwartz, J., Hou, L., Jafari, N., Sun, Z., Kocher, J. P. A., Baccarelli, A. & Lin, X., Feb 1 2016, In: Bioinformatics. 32, 3, p. 469-471 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Intraclass Correlation Coefficient 100%
  • Epigenome 84%
  • Probe 81%
  • Measurement errors 69%
  • Filtering 67%
  13 Scopus citations

• Enhancer of zeste homolog 2 inhibition stimulates bone formation and mitigates bone loss caused by ovariectomy in skeletally mature mice

  Dudakovic, A., Camilleri, E. T., Riester, S. M., Paradise, C. R., Gluscevic, M., O'Toole, T. M., Thaler, R., Evans, J. M., Yan, H., Subramaniam, M., Hawse, J. R., Stein, G. S., Montecino, M. A., McGee-Lawrence, M. E., Westendorf, J. J. & Van Wijnen, A. J., Nov 18 2016, In: Journal of Biological Chemistry. 291, 47, p. 24594-24606 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Enhancer of Zeste Homolog 2 Protein 100%
  • Enhancer 77%
  • Ovariectomy 72%
  • Osteogenesis 57%
  • Bone and Bones 38%
  43 Scopus citations

• Extracting drug-enzyme relation from literature as evidence for drug drug interaction

  Zhang, Y., Wu, H. Y., Du, J., Xu, J., Wang, J., Tao, C., Li, L. & Xu, H., Mar 7 2016, In: Journal of Biomedical Semantics. 7, 1, 11.

  Research output: Contribution to journal › Article › peer-review

  • Drug interactions 100%
  • Enzymes 73%
  • Drug Interactions 62%
  • Pharmaceutical Preparations 26%
  • Datasets 16%
  5 Scopus citations

• Genome-Wide Epigenetic Studies in Human Disease: A Primer on -Omic Technologies

  Yan, H., Tian, S., Slager, S. L., Sun, Z. & Ordog, T., Jan 15 2016, In: American journal of epidemiology. 183, 2, p. 96-109 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Epigenomics 100%
  • Genome 77%
  • Technology 74%
  • Chromatin 37%
  • DNA Methylation 28%
  17 Scopus citations

• GWASdb v2: An update database for human genetic variants identified by genome-wide association studies

  Li, M. J., Liu, Z., Wang, P., Wong, M. P., Nelson, M. R., Kocher, J. P. A., Yeager, M., Sham, P. C., Chanock, S. J., Xia, Z. & Wang, J., 2016, In: Nucleic acids research. 44, D1, p. D869-D876

  Research output: Contribution to journal › Article › peer-review

  • Human Genetics 100%
  • Genome-Wide Association Study 85%
  • Single Nucleotide Polymorphism 68%
  • Databases 49%
  • Publications 19%
  94 Scopus citations

• High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma

  Ho, T. H., Park, I. Y., Zhao, H., Tong, P., Champion, M. D., Yan, H., Monzon, F. A., Hoang, A., Tamboli, P., Parker, A. S., Joseph, R. W., Qiao, W., Dykema, K., Tannir, N. M., Castle, E. P., Nunez-Nateras, R., Teh, B. T., Wang, J., Walker, C. L., Hung, M. C. & 1 others, Jonasch, E., Mar 24 2016, In: Oncogene. 35, 12, p. 1565-1574 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Lysine 100%
  • Renal Cell Carcinoma 98%
  • Histones 96%
  • Neoplasm Metastasis 21%
  • Clear-cell metastatic renal cell carcinoma 18%
  39 Scopus citations

• Impact of post-alignment processing in variant discovery from whole exome data

  Tian, S., Yan, H., Kalmbach, M. & Slager, S. L., Oct 3 2016, In: BMC bioinformatics. 17, 1, 403.

  Research output: Contribution to journal › Article › peer-review

  • Post-processing 100%
  • Exome 99%
  • Pipeline 95%
  • Alignment 95%
  • Antigens 74%
  12 Scopus citations

• MC11C4: a pilot randomized, placebo-controlled, double-blind study of venlafaxine to prevent oxaliplatin-induced neuropathy

  Zimmerman, C., Atherton, P. J., Pachman, D., Seisler, D., Wagner-Johnston, N., Dakhil, S., Lafky, J. M., Qin, R., Grothey, A. & Loprinzi, C. L., Mar 1 2016, In: Supportive Care in Cancer. 24, 3, p. 1071-1078 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Venlafaxine Hydrochloride 100%
  • Oxaliplatin 88%
  • Double-Blind Method 73%
  • Placebos 51%
  • Physicians 11%
  25 Scopus citations

• Measure transcript integrity using RNA-seq data

  Wang, L., Nie, J., Sicotte, H., Li, Y., Eckel-Passow, J. E., Dasari, S., Vedell, P. T., Barman, P., Wang, L., Weinshiboum, R., Jen, J., Huang, H., Kohli, M. & Kocher, J. P. A., Feb 3 2016, In: BMC bioinformatics. 17, 1, 58.

  Research output: Contribution to journal › Article › peer-review

  • Integrity 100%
  • RNA-Seq 88%
  • RNA Stability 83%
  • Degradation 51%
  • RNA 42%
  70 Scopus citations

• Olanzapine for the prevention of chemotherapy-induced nausea and vomiting

  Navari, R. M., Qin, R., Ruddy, K. J., Liu, H., Powell, S. F., Bajaj, M., Dietrich, L., Biggs, D., Lafky, J. M. & Loprinzi, C. L., Jul 14 2016, In: New England Journal of Medicine. 375, 2, p. 134-142 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Olanzapine 100%
  • Nausea 72%
  • Vomiting 71%
  • Drug Therapy 48%
  • Placebos 35%
  193 Scopus citations

• Phase i trial of FOLFIRI in combination with sorafenib and bevacizumab in patients with advanced gastrointestinal malignancies

  Hubbard, J. M., Kim, G., Borad, M. J., Johnson, E., Qin, R., Lensing, J., Puttabasavaiah, S., Wright, J., Erlichman, C. & Grothey, A., Feb 1 2016, In: Investigational New Drugs. 34, 1, p. 96-103 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sorafenib 100%
  • Bevacizumab 90%
  • Neoplasms 26%
  • Hypophosphatemia 18%
  • Leucovorin 16%
  1 Scopus citations

• Predicting regulatory variants with composite statistic

  Li, M. J., Pan, Z., Liu, Z., Wu, J., Wang, P., Zhu, Y., Xu, F., Xia, Z., Sham, P. C., Kocher, J. P. A., Li, M., Liu, J. S. & Wang, J., Sep 15 2016, In: Bioinformatics. 32, 18, p. 2729-2736 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Precision Medicine 100%
  • Genomics 93%
  • Composite 81%
  • Statistic 80%
  • Virulence 80%
  21 Scopus citations

• Retinoblastoma Binding Protein 4 Modulates Temozolomide Sensitivity in Glioblastoma by Regulating DNA Repair Proteins

  Kitange, G. J., Mladek, A. C., Schroeder, M. A., Pokorny, J. C., Carlson, B. L., Zhang, Y., Nair, A. A., Lee, J. H., Yan, H., Decker, P. A., Zhang, Z. H. & Sarkaria, J. N., Mar 22 2016, In: Cell reports. 14, 11, p. 2587-2598 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Retinoblastoma-Binding Protein 4 100%
  • Temozolomide 78%
  • Glioblastoma 48%
  • DNA Repair 45%
  • Methyltransferases 32%
  28 Scopus citations

• Targeted alignment and end repair elimination increase alignment and methylation measure accuracy for reduced representation bisulfite sequencing data

  Baheti, S., Kanwar, R., Goelzenleuchter, M., Kocher, J. P. A., Beutler, A. S. & Sun, Z., Feb 27 2016, In: BMC genomics. 17, 1, 149.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hydrogen sulfite 100%
  • Cytosine 93%
  • Methylation 71%
  • Datasets 23%
  • DNA Methylation 19%

• Trivalent influenza vaccine adverse symptoms analysis based on MedDRA terminology using VAERS data in 2011

  Du, J., Cai, Y., Chen, Y. & Tao, C., Jun 14 2016, In: Journal of Biomedical Semantics. 7, 1, 13.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vaccines 100%
  • Viruses 85%
  • Influenza Vaccines 83%
  • Terminology 79%
  • Research Design 58%
  3 Scopus citations

• VCF-Miner: GUI-based application for mining variants and annotations stored in VCF files

  Hart, S. N., Duffy, P., Quest, D. J., Hossain, A., Meiners, M. A. & Kocher, J. P., Mar 1 2016, In: Briefings in bioinformatics. 17, 2, p. 346-351 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Miners 100%
  • Graphical user interfaces 75%
  • Specifications 24%
  • Trimming 23%
  • Microcomputers 22%
  30 Scopus citations

• “Enjoy glass of wine before eating:” a randomized trial to test the orexigenic effects of this advice in advanced cancer patients

  Jatoi, A., Qin, R., Satele, D., Dakhil, S., Kumar, P., Johnson, D. B., Thomas, S. P., Stella, P. J., Castillo, J., Li, M. & Fernandez-Zapico, M., Sep 1 2016, In: Supportive Care in Cancer. 24, 9, p. 3739-3746 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Wine 100%
  • Glass 78%
  • Appetite 66%
  • Eating 61%
  • Neoplasms 26%
  3 Scopus citations
• 2015

  A multidisciplinary biospecimen bank of renal cell carcinomas compatible with discovery platforms at Mayo Clinic, Scottsdale, Arizona

  Ho, T. H., Nateras, R. N., Yan, H., Park, J. G., Jensen, S., Borges, C., Lee, J. H., Champion, M. D., Tibes, R., Bryce, A. H., Carballido, E. M., Todd, M. A., Joseph, R. W., Wong, W. W., Parker, A. S., Stanton, M. L. & Castle, E. P., Jul 16 2015, In: PloS one. 10, 7, e0132831.

  Research output: Contribution to journal › Article › peer-review

  • renal cell carcinoma 100%
  • Renal Cell Carcinoma 59%
  • Chromatin Immunoprecipitation Sequencing 39%
  • Plasma 37%
  • topographic maps 37%
  6 Scopus citations

• A phase II trial of bevacizumab plus temsirolimus in patients with advanced hepatocellular carcinoma

  Knox, J. J., Qin, R., Strosberg, J. R., Tan, B., Kaubisch, A., El-Khoueiry, A. B., Bekaii-Saab, T. S., Rousey, S. R., Chen, H. X. & Erlichman, C., Feb 2015, In: Investigational New Drugs. 33, 1, p. 241-246 6 p.

  Research output: Contribution to journal › Article › peer-review

  • temsirolimus 100%
  • Bevacizumab 74%
  • Hepatocellular Carcinoma 53%
  • PR 26 23%
  • Medical Futility 15%
  21 Scopus citations

• Association of the Charcot–Marie–Tooth disease gene ARHGEF10 with paclitaxel induced peripheral neuropathy in NCCTG N08CA (Alliance)

  Boora, G. K., Kulkarni, A. A., Kanwar, R., Beyerlein, P., Qin, R., Banck, M. S., Ruddy, K. J., Pleticha, J., Lynch, C. A., Behrens, R. J., Züchner, S., Loprinzi, C. L. & Beutler, A. S., Oct 15 2015, In: Journal of the neurological sciences. 357, 1-2, p. 35-40 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Peripheral Nervous System Diseases 100%
  • Paclitaxel 96%
  • Drug Therapy 55%
  • Nucleotides 46%
  • Polyneuropathies 44%
  27 Scopus citations

• Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-α Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1α and Mitochondrial Homeostasis

  Wang, Y., Cao, Y., Yamada, S., Thirunavukkarasu, M., Nin, V., Joshi, M., Rishi, M. T., Bhattacharya, S., Camacho-Pereira, J., Sharma, A. K., Shameer, K., Kocher, J. P. A., Sanchez, J. A., Wang, E., Hoeppner, L. H., Dutta, S. K., Leof, E. B., Shah, V., Claffey, K. P., Chini, E. N. & 4 others, Simons, M., Terzic, A., Maulik, N. & Mukhopadhyay, D., Jun 27 2015, In: Arteriosclerosis, thrombosis, and vascular biology. 35, 6, p. 1401-1412 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuropilin-1 100%
  • Cardiomyopathies 65%
  • Homeostasis 49%
  • Heart Failure 49%
  • Peroxisome Proliferator-Activated Receptors 40%
  20 Scopus citations

• Chromosome X genomic and epigenomic aberrations and clinical implications in breast cancer by base resolution profiling

  Sun, Z., Prodduturi, N., Sun, S. Y., Thompson, E. A. & Kocher, J. P. A., Oct 2015, In: Epigenomics. 7, 7, p. 1099-1110 12 p.

  Research output: Contribution to journal › Article › peer-review

  • X Chromosome 100%
  • Epigenomics 77%
  • Breast Neoplasms 56%
  • DNA Methylation 35%
  • Cell Line 31%
  5 Scopus citations

• Clinical course of oxaliplatin-induced neuropathy: Results from the randomized phase III trial N08CB (Alliance)

  Pachman, D. R., Qin, R., Seisler, D. K., Smith, E. M. L., Beutler, A. S., Ta, L. E., Lafky, J. M., Wagner-Johnston, N. D., Ruddy, K. J., Dakhil, S., Staff, N. P., Grothey, A. & Loprinzi, C. L., Oct 20 2015, In: Journal of Clinical Oncology. 33, 30, p. 3416-3422 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxaliplatin 100%
  • Cold Temperature 30%
  • Drug Therapy 29%
  • Foot 28%
  • Hand 25%
  121 Scopus citations

• Colorectal cancer drug target prediction using ontology-based inference and network analysis

  Tao, C., Sun, J., Zheng, W. J., Chen, J. & Xu, H., 2015, In: Database. 2015, bav015.

  Research output: Contribution to journal › Article › peer-review

  • colorectal neoplasms 100%
  • Drug Target 93%
  • Electric network analysis 82%
  • Genes 78%
  • Drug Development 77%
  17 Scopus citations

• Combining clinicopathological predictors and molecular biomarkers in the oncogenic K-RAS/Ki67/HIF-1α pathway to predict survival in resectable pancreatic cancer

  Qin, R., Smyrk, T. C., Reed, N. R., Schmidt, R. L., Schnelldorfer, T., Chari, S. T., Petersen, G. M. & Tang, A. H., Feb 3 2015, In: British journal of cancer. 112, 3, p. 514-522 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Neoplasms 100%
  • Biomarkers 68%
  • Survival 58%
  • Hypoxia 27%
  • Tumor Biomarkers 17%
  28 Scopus citations

• Developing VISO: Vaccine Information Statement Ontology for patient education

  Amith, M., Gong, Y., Cunningham, R., Boom, J. & Tao, C., May 1 2015, In: Journal of Biomedical Semantics. 6, 1, 23.

  Research output: Contribution to journal › Article › peer-review

  • Vaccines 100%
  • Patient Education 75%
  • Education 61%
  • Ontology 61%
  • Disease control 15%
  11 Scopus citations

• Epidaurus: Aggregation and integration analysis of prostate cancer epigenome

  Wang, L., Huang, H., Dougherty, G., Zhao, Y., Hossain, A. & Kocher, J. P. A., Jan 30 2015, In: Nucleic acids research. 43, 2, p. e7

  Research output: Contribution to journal › Article › peer-review

  • Epigenome 100%
  • Epigenomics 70%
  • Prostatic Neoplasms 63%
  • Datasets 47%
  • Androgen Receptors 43%
  5 Scopus citations

• Glmgraph: An R package for variable selection and predictive modeling of structured genomic data

  Chen, L., Liu, H., Kocher, J. P. A., Li, H. & Chen, J., Jul 3 2015, In: Bioinformatics. 31, 24, p. 3991-3993 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Predictive Modeling 100%
  • Genomics 71%
  • Variable Selection 62%
  • Data Analysis 45%
  • Bacterial Structures 43%
  8 Scopus citations

• Identification of sex-associated network patterns in Vaccine-Adverse Event Association Network in VAERS

  Zhang, Y., Wu, P., Luo, Y. & Tao, C., Aug 19 2015, In: Journal of Biomedical Semantics. 6, 1, 33.

  Research output: Contribution to journal › Article › peer-review

  • Vaccines 100%
  • Research Design 10%
  • Vaccinology 10%
  • Electric network analysis 6%
  • Communicable Diseases 5%
  3 Scopus citations

• Multicenter phase II trial of temsirolimus and bevacizumab in pancreatic neuroendocrine tumors

  Hobday, T. J., Qin, R., Reidy-Lagunes, D., Moore, M. J., Strosberg, J., Kaubisch, A., Shah, M., Kindler, H. L., Lenz, H. J., Chen, H. & Erlichman, C., May 10 2015, In: Journal of Clinical Oncology. 33, 14, p. 1551-1556 6 p.

  Research output: Contribution to journal › Article › peer-review

  • temsirolimus 100%
  • Neuroendocrine Tumors 75%
  • Bevacizumab 74%
  • Progression-Free Survival 43%
  • TOR Serine-Threonine Kinases 42%
  76 Scopus citations

• Mutational landscapes of sequential prostate metastases and matched patient derived xenografts during enzalutamide therapy

  Kohli, M., Wang, L., Xie, F., Sicotte, H., Yin, P., Dehm, S. M., Hart, S. N., Vedell, P. T., Barman, P., Qin, R., Mahoney, D. W., Carlson, R. E., Eckel-Passow, J. E., Atwell, T. D., Eiken, P. W., Mcmenomy, B. P., Wieben, E. D., Jha, G., Jimenez, R. E., Weinshilboum, R. & 1 others, Wang, L., Dec 1 2015, In: PloS one. 10, 12, 0145176.

  Research output: Contribution to journal › Article › peer-review

  • MDV 3100 100%
  • Heterografts 60%
  • Prostate 56%
  • Neoplasm Metastasis 41%
  • Whole Exome Sequencing 26%
  17 Scopus citations

• North Central Cancer Treatment group N10C2 (Alliance): A double-blind placebo-controlled study of magnesium supplements to reduce menopausal hot flashes

  Park, H., Qin, R., Smith, T. J., Atherton, P. J., Barton, D. L., Sturtz, K., Dakhil, S. R., Anderson, D. M., Flynn, K., Puttabasavaiah, S., Le-Lindqwister, N. A., Padula, G. D. A. & Loprinzi, C. L., Jun 6 2015, In: Menopause. 22, 6, p. 627-632 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Hot Flashes 100%
  • Magnesium 71%
  • Placebos 49%
  • Neoplasms 22%
  • Magnesium Oxide 20%
  15 Scopus citations

• Oncogenes and tumor suppressor genes: Comparative genomics and network perspectives

  Zhu, K., Liu, Q., Zhou, Y., Tao, C., Zhao, Z., Sun, J. & Xu, H., Jun 11 2015, In: BMC genomics. 16, 7, S8.

  Research output: Contribution to journal › Article › peer-review

  • Genomics 100%
  • Tumor Suppressor Genes 97%
  • Oncogenes 94%
  • Proteins 30%
  • Neoplasms 27%
  22 Scopus citations

• PANDA: Pathway and annotation explorer for visualizing and interpreting gene-centric data

  Hart, S. N., Moore, R. M., Zimmermann, M. T., Oliver, G. R., Egan, J. B., Bryce, A. H. & Kocher, J. P. A., 2015, In: PeerJ. 2015, 5, e970.

  Research output: Contribution to journal › Article › peer-review

  • Molecular Sequence Annotation 100%
  • Instrumentation 73%
  • Information Storage and Retrieval 68%
  • precision medicine 61%
  • renal cell carcinoma 61%
  3 Scopus citations

• Predictive value of plasma biomarkers for mortality and organ failure development in patients with acute respiratory distress syndrome

  Cartin-Ceba, R., Hubmayr, R. D., Qin, R., Peters, S., Determann, R. M., Schultz, M. J. & Gajic, O., Feb 1 2015, In: Journal of Critical Care. 30, 1, p. 219.e1-219.e7

  Research output: Contribution to journal › Article › peer-review

  • Multiple Organ Failure 100%
  • Adult Respiratory Distress Syndrome 93%
  • Biomarkers 55%
  • Mortality 43%
  • Hospital Mortality 32%
  19 Scopus citations

• PVAAS: Identify variants associated with aberrant splicing from RNA-seq

  Wang, L., Nie, J. J. & Kocher, J. P. A., May 15 2015, In: Bioinformatics. 31, 10, p. 1668-1670 3 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA-Seq 96%
  • Alternative Splicing 74%
  • Microarray 52%
  • Leverage 52%
  • Nucleotides 51%
  2 Scopus citations

• Quality Assurance of Cancer Study Common Data Elements Using A Post-Coordination Approach

  Jiang, G., Solbrig, H. R., Prud'hommeaux, E., Tao, C., Weng, C. & Chute, C. G., 2015, In: AMIA ... Annual Symposium proceedings. AMIA Symposium. 2015, p. 659-668 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Common Data Elements 100%
  • Neoplasms 18%
  • Atlases 15%
  • Clinical Studies 9%
  • Genome 9%
  4 Scopus citations

• Risk of Asthma in Late Preterm Infants: A Propensity Score Approach

  Voge, G. A., Katusic, S. K., Qin, R. & Juhn, Y. J., Nov 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 6, p. 905-910 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Propensity Score 100%
  • Premature Infants 89%
  • Asthma 72%
  • Premature Birth 28%
  • Term Birth 17%
  14 Scopus citations

• RNA toxicity and missplicing in the common eye disease fuchs endothelial corneal dystrophy

  Du, J., Aleff, R. A., Soragni, E., Kalari, K., Nie, J., Tang, X., Davila, J., Kocher, J. P., Patel, S. V., Gottesfeld, J. M., Baratz, K. H. & Wieben, E. D., Mar 6 2015, In: Journal of Biological Chemistry. 290, 10, p. 5979-5990 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Fuchs' Endothelial Dystrophy 100%
  • Neuromuscular 89%
  • Eye Diseases 66%
  • Disorder 54%
  • Monolayer 47%
  75 Scopus citations

• Safety and activity of temsirolimus and bevacizumab in patients with advanced renal cell carcinoma previously treated with tyrosine kinase inhibitors: A phase 2 consortium study

  Merchan, J. R., Qin, R., Pitot, H., Picus, J., Liu, G., Fitch, T., Maples, W. J., Flynn, P. J., Fruth, B. F. & Erlichman, C., Mar 2015, In: Cancer chemotherapy and pharmacology. 75, 3, p. 485-493 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Temsirolimus 100%
  • temsirolimus 73%
  • Tyrosine Kinase Inhibitor 68%
  • Bevacizumab 54%
  • Renal Cell Carcinoma 47%
  14 Scopus citations