Biochemistry and Molecular Biology

Research Output 1973 2020

2020

Fructose-1,6-bisphosphatase loss modulates STAT3-dependent expression of PD-L1 and cancer immunity

Wang, B., Zhou, Y., Zhang, J., Jin, X., Wu, H. & Huang, H., Jan 1 2020, In : Theranostics. 10, 3, p. 1033-1045 13 p.

Research output: Contribution to journalArticle

Open Access
Fructose-Bisphosphatase
STAT3 Transcription Factor
Immunity
Ligands
Neoplasms

Influence of water based embedding media composition on the relaxation properties of fixed tissue

Vučković, I., Nayfeh, T., Mishra, P. K., Periyanan, S., Sussman, C. R., Kline, T. L. & Macura, S., Apr 2020, In : Magnetic Resonance Imaging. 67, p. 7-17 11 p.

Research output: Contribution to journalArticle

Fixatives
Formaldehyde
Tissue
Water
Phosphates

Ultrasound image processing to estimate the structural and functional properties of mouse skeletal muscle

Ternifi, R., Kammoun, M., Pouletaut, P., Subramaniam, M., Hawse, J. R. & Bensamoun, S. F., Feb 2020, In : Biomedical Signal Processing and Control. 56, 101735.

Research output: Contribution to journalArticle

Muscle
Skeletal Muscle
Image processing
Ultrasonics
Muscles
2019

A conditional mouse model of complex II deficiency manifesting as Leigh-like syndrome

Al Khazal, F., Holte, M. N., Bolon, B., White, T. A., LeBrasseur, N. & Maher, L. J., Dec 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 12, p. 13189-13201 13 p.

Research output: Contribution to journalArticle

Leigh Disease
Succinate Dehydrogenase
Metabolism
Tumors
Inborn Errors Metabolism
1 Citation (Scopus)

Acquisition, Processing and Analysis of Electrocardiogram in Awake Zebrafish

Le, T., Lenning, M., Clark, I., Bhimani, I., Fortunato, J., Marsh, P., Xu, X. H. & Cao, H., Jun 1 2019, In : IEEE Sensors Journal. 19, 11, p. 4283-4289 7 p., 8636511.

Research output: Contribution to journalArticle

electrocardiography
Electrocardiography
acquisition
drugs
electrophysiology

Amplification-free long-read sequencing of TCF4 expanded trinucleotide repeats in Fuchs Endothelial Corneal Dystrophy

Wieben, E. D., Aleff, R. A., Basu, S., Sarangi, V., Bowman, B., McLaughlin, I. J., Mills, J. R., Butz, M. L., Highsmith, W. E. J., Ida, C. M., Ekholm, J. M., Baratz, K. & Fautsch, M. P., Jan 1 2019, In : PloS one. 14, 7, e0219446.

Research output: Contribution to journalArticle

Open Access
Fuchs' Endothelial Dystrophy
Trinucleotide Repeat Expansion
Trinucleotide Repeats
Amplification
microsatellite repeats

An in Vitro Selection Strategy Identifying Naked DNA That Localizes to Cell Nuclei

Smestad, J., Wilbanks, B. & Maher, L. J., Nov 20 2019, In : Journal of the American Chemical Society. 141, 46, p. 18375-18379 5 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
Cell Nucleus
DNA
Antibody Diversity
Cells
1 Citation (Scopus)

Assays for light chain amyloidosis formation and cytotoxicity

Blancas-Mejia, L. M., Misra, P., Dick, C. J., Marin-Argany, M., Redhage, K. R., Cooper, S. A. & Ramirez-Alvarado, M., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 123-153 31 p. (Methods in Molecular Biology; vol. 1873).

Research output: Chapter in Book/Report/Conference proceedingChapter

Amyloidosis
Immunoglobulin Light Chains
Light
Fluorescence Spectrometry
Fluorescence Microscopy

Association of rs613872 and Trinucleotide Repeat Expansion in the TCF4 Gene of German Patients With Fuchs Endothelial Corneal Dystrophy

Okumura, N., Hayashi, R., Nakano, M., Tashiro, K., Yoshii, K., Aleff, R., Butz, M., Highsmith, W. E. J., Wieben, E. D., Fautsch, M. P., Baratz, K., Komori, Y., Ueda, E., Nakahara, M., Weller, J., Tourtas, T., Schlötzer-Schrehardt, U., Kruse, F. & Koizumi, N., Jul 1 2019, In : Cornea. 38, 7, p. 799-805 7 p.

Research output: Contribution to journalArticle

Fuchs' Endothelial Dystrophy
Trinucleotide Repeat Expansion
Trinucleotide Repeats
Transcription Factors
Single Nucleotide Polymorphism

Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function (Nature, (2019), 571, 7765, (403-407), 10.1038/s41586-019-1311-3)

Bailis, W., Shyer, J. A., Zhao, J., Canaveras, J. C. G., Al Khazal, F. J., Qu, R., Steach, H. R., Bielecki, P., Khan, O., Jackson, R., Kluger, Y., Maher III, L. J., Rabinowitz, J., Craft, J. & Flavell, R. A., Jan 1 2019, (Accepted/In press) In : Nature.

Research output: Contribution to journalComment/debate

Open Access
Cell Differentiation
Medicine
T-Lymphocytes

CAR T Cell Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological Malignancies

Mochel, J. P., Ekker, S. C., Johannes, C. M., Jergens, A. E., Allenspach, K., Bourgois-Mochel, A., Knouse, M., Benzekry, S., Wierson, W., LeBlanc, A. K. & Kenderian, S., May 1 2019, In : AAPS Journal. 21, 3, 50.

Research output: Contribution to journalComment/debate

Hematologic Neoplasms
T-Cell Antigen Receptor
Antigen Receptors
Immunotherapy
Canidae

Case-Based Learning in Translational Biomedical Research Education: Providing Realistic and Adaptive Skills for Early-Career Scientists

Greenberg-Worisek, A. J., Campbell, K. A., Klee, E. W., Staff, N. P., Schimmenti, L. A., Weavers, K. M., Ekker, S. C. & Windebank, A. J., Feb 1 2019, In : Academic medicine : journal of the Association of American Medical Colleges. 94, 2, p. 213-216 4 p.

Research output: Contribution to journalArticle

career
science
learning
education
medicine
3 Citations (Scopus)

Clinical features, laboratory characteristics and outcomes of patients with renal versus cardiac light chain amyloidosis

Sidana, S., Tandon, N., Gertz, M., Dispenzieri, A., Ramirez-Alvarado, M., Murray, D. L., Kourelis, T., Buadi, F. K., Kapoor, P., Gonsalves, W., Warsame, R., Lacy, M., Kyle, R. A., Rajkumar, S. V., Kumar, S. K. & Leung, N., Jan 1 2019, In : British journal of haematology.

Research output: Contribution to journalArticle

Amyloidosis
Kidney
Light
Plasma Cells
Bone Marrow Cells
Open Access
Immunoglobulin Light Chains
Glycosylation
Publications
Early Diagnosis
Leukemia

Corrigendum to “Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy” [Heliyon 4 (12) (December 2018) e01039] (Heliyon (2018) 4(12), (S2405844018323442), (10.1016/j.heliyon.2018.e01039))

Wu, X., Li, Y., Liu, X., Chen, C., Harrington, S. M., Cao, S., Xie, T., Pham, T., Mansfield, A., Yan, Y., Kwon, E. D., Wang, L. M., Ling, K. & Dong, H. M., Mar 1 2019, In : Heliyon. 5, 3, e01309.

Research output: Contribution to journalComment/debate

Open Access
Drug Therapy
Neoplasms
corrigendum
3 Citations (Scopus)

Design, Synthesis, and Actions of an Innovative Bispecific Designer Peptide

Meems, L. M. G., Andersen, I. A., Pan, S., Harty, G., Chen, Y., Zheng, Y., Harders, G. E., Ichiki, T., Heublein, D. M., Iyer, S. R., Sangaralingham, S. J., Mc Cormick, D. J. & Burnett, J. C. J., Apr 1 2019, In : Hypertension (Dallas, Tex. : 1979). 73, 4, p. 900-909 10 p.

Research output: Contribution to journalArticle

Peptides
Cardiovascular Diseases
Therapeutics
Canidae
Ligands
2 Citations (Scopus)

Development of a novel multiphysical approach for the characterization of mechanical properties of musculotendinous tissues

Kammoun, M., Ternifi, R., Dupres, V., Pouletaut, P., Même, S., Même, W., Szeremeta, F., Landoulsi, J., Constans, J. M., Lafont, F., Subramaniam, M., Hawse, J. R. & Bensamoun, S. F., Dec 1 2019, In : Scientific reports. 9, 1, 7733.

Research output: Contribution to journalArticle

Open Access
Tendons
Elasticity Imaging Techniques
Atomic Force Microscopy
Muscles
Elasticity
1 Citation (Scopus)

Displacement analysis of myocardial mechanical deformation (DIAMOND) reveals segmental susceptibility to doxorubicin-induced injury and regeneration

Chen, J., Ding, Y., Chen, M., Gau, J., Jen, N., Nahal, C., Tu, S., Chen, C., Zhou, S., Chang, C. C., Lyu, J., Xu, X. H., Hsiai, T. K. & Packard, R. R. S., Jan 1 2019, In : JCI Insight. 4, 8, e125362.

Research output: Contribution to journalArticle

Open Access
Zebrafish
Doxorubicin
Regeneration
Wounds and Injuries
Mechanics
5 Citations (Scopus)

Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function

Bailis, W., Shyer, J. A., Zhao, J., Canaveras, J. C. G., Al Khazal, F. J., Qu, R., Steach, H. R., Bielecki, P., Khan, O., Jackson, R., Kluger, Y., Maher III, L. J., Rabinowitz, J., Craft, J. & Flavell, R. A., Jan 1 2019, In : Nature.

Research output: Contribution to journalLetter

Cell Differentiation
Th1 Cells
T-Lymphocytes
Citric Acid
Succinate Dehydrogenase
1 Citation (Scopus)

Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy

Okumura, N., Hayashi, R., Nakano, M., Yoshii, K., Tashiro, K., Sato, T., Blake, D. J., Aleff, R., Butz, M., Highsmith, W. E. J., Wieben, E. D., Fautsch, M. P., Baratz, K., Komori, Y., Nakahara, M., Tourtas, T., Schlötzer-Schrehardt, U., Kruse, F. & Koizumi, N., Feb 1 2019, In : Investigative ophthalmology & visual science. 60, 2, p. 779-786 8 p.

Research output: Contribution to journalArticle

Open Access
Fuchs' Endothelial Dystrophy
Trinucleotide Repeat Expansion
Transcription Factors
Messenger RNA
Corneal Endothelium

Establishment of TUSMi008-A, an induced pluripotent stem cell (iPSC) line from a 76-year old Alzheimer's disease (AD) patient with PAXIP1 gene mutation

Wang, Y., Zhang, J., Hu, J., Li, G., Lei, Y. & Zhao, J., Apr 1 2019, In : Stem Cell Research. 36, 101391.

Research output: Contribution to journalArticle

Open Access
Induced Pluripotent Stem Cells
Alzheimer Disease
Cell Line
Germ Layers
Mutation
1 Citation (Scopus)

Evidence for a bind-then-bend mechanism for architectural DNA binding protein yNhp6A

Sarangi, M. K., Zvoda, V., Holte, M. N., Becker, N. A., Peters, J. P., Maher III, L. J. & Ansari, A., Apr 8 2019, In : Nucleic acids research. 47, 6, p. 2871-2883 13 p.

Research output: Contribution to journalArticle

Open Access
Fungal Proteins
DNA-Binding Proteins
DNA
HMGB Proteins
Nucleic Acid Conformation
7 Citations (Scopus)

EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis

Zhao, Y., Ding, L., Wang, D., Ye, Z., He, Y., Ma, L., Zhu, R., Pan, Y., Wu, Q., Pang, K., Hou, X., Weroha, S. J., Han, C., Coleman, R., Coleman, I., Karnes, R. J., Zhang, J., Nelson, P. S., Wang, L. & Huang, H., Jan 1 2019, In : EMBO Journal. e99599.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Growth
Protein Biosynthesis
Neoplasms
RNA Sequence Analysis
2 Citations (Scopus)

Familial chronic megacolon presenting in childhood or adulthood: Seeking the presumed gene association

Camilleri, M., Wieben, E. D., Eckert, D., Carlson, P., Hurley O’Dwyer, R., Gibbons, D., Acosta, A. & Klee, E. W., Jan 1 2019, (Accepted/In press) In : Neurogastroenterology and Motility. e13550.

Research output: Contribution to journalArticle

Megacolon
Genes
DNA
Dilatation
Colon
Open Access
Fuchs' Endothelial Dystrophy
Trinucleotide Repeat Expansion
Corneal Endothelium
Gene Expression
Corneal Diseases
1 Citation (Scopus)

Glial cells as therapeutic targets in progressive multiple sclerosis

Wilbanks, B., Maher III, L. J. & Rodriguez, M., Jun 1 2019, In : Expert review of neurotherapeutics. 19, 6, p. 481-494 14 p.

Research output: Contribution to journalArticle

Neuroglia
Multiple Sclerosis
Therapeutics
Central Nervous System
Oligodendroglia

Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish

Ding, Y., Dvornikov, A. V., Ma, X., Zhang, H., Wang, Y., Lowerison, M., Packard, R. R., Wang, L., Chen, J., Zhang, Y., Hsiai, T., Lin, X. & Xu, X., Oct 1 2019, In : Disease models & mechanisms. 12, 10

Research output: Contribution to journalArticle

Open Access
Haploinsufficiency
Zebrafish
Sirolimus
Cardiomyopathies
Dilated Cardiomyopathy

Impaired Muscle Regeneration in Cancer-Associated Cachexia

Arneson, P. C. & Doles, J., Jan 1 2019, (Accepted/In press) In : Trends in Cancer.

Research output: Contribution to journalShort survey

Cachexia
Regeneration
Muscles
Neoplasms
Muscle Cells

Interplay Among PI3K/AKT, PTEN/FOXO and AR Signaling in Prostate Cancer

Yan, Y. & Huang, H., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer, p. 319-331 13 p. (Advances in Experimental Medicine and Biology; vol. 1210).

Research output: Chapter in Book/Report/Conference proceedingChapter

Phosphatidylinositol 3-Kinases
Prostatic Neoplasms
Carcinogenesis
Genes
Mutation
1 Citation (Scopus)

Lineage plasticity-mediated therapy resistance in prostate cancer

Blee, A. & Huang, H., May 1 2019, In : Asian Journal of Andrology. 21, 3, p. 241-248 8 p.

Research output: Contribution to journalReview article

Open Access
Prostatic Neoplasms
Androgen Receptors
Androgens
Therapeutics
Neoplasms
1 Citation (Scopus)

Male breast cancer in the United States: Treatment patterns and prognostic factors in the 21st century

Yadav, S., Karam, D., Bin Riaz, I., Xie, H., Durani, U., Duma, N., Giridhar, K. V., Hieken, T. J., Boughey, J. C., Mutter, R. W., Hawse, J. R., Jimenez, R. E., Couch, F. J., Leon-Ferre, R. A. & Ruddy, K. J., Jan 1 2019, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

Male Breast Neoplasms
Simple Mastectomy
Radiotherapy
Therapeutics
Survival

Master regulator analysis of paragangliomas carrying SDHx, VHL, or MAML3 genetic alterations

Smestad, J. A. & Maher, J. L., Jun 24 2019, In : BMC cancer. 19, 1, 619.

Research output: Contribution to journalArticle

Open Access
Paraganglioma
Succinate Dehydrogenase
Transcription Factors
Tretinoin
Neoplasms

Measurement of murine kidney functional biomarkers using DCE-MRI: A multi-slice TRICKS technique and semi-automated image processing algorithm

Jiang, K., Tang, H., Mishra, P. K., Macura, S. I. & Lerman, L. O., Nov 1 2019, In : Magnetic Resonance Imaging. 63, p. 226-234 9 p.

Research output: Contribution to journalArticle

Biomarkers
Magnetic resonance imaging
Image processing
Kidney
Imaging techniques

Mechanistic Insights into the Early Events in the Aggregation of Immunoglobulin Light Chains

Misra, P., Blancas-Mejia, L. M. & Ramirez-Alvarado, M., Jun 25 2019, In : Biochemistry. 58, 29, p. 3155-3168 14 p.

Research output: Contribution to journalArticle

Immunoglobulin Light Chains
Amyloid
Amyloidosis
Agglomeration
Dimers

Mitsui-7, heat-treated, and nitrogen-doped multi-walled carbon nanotubes elicit genotoxicity in human lung epithelial cells

Siegrist, K. J., Reynolds, S. H., Porter, D. W., Mercer, R. R., Bauer, A. K., Lowry, D., Cena, L., Stueckle, T. A., Kashon, M. L., Wiley, J., Salisbury, J. L., Mastovich, J., Bunker, K., Sparrow, M., Lupoi, J. S., Stefaniak, A. B., Keane, M. J., Tsuruoka, S., Terrones, M., McCawley, M. & 1 others, Sargent, L. M., Oct 7 2019, In : Particle and Fibre Toxicology. 16, 1, 36.

Research output: Contribution to journalArticle

Open Access
Carbon Nanotubes
Nitrogen
Hot Temperature
Epithelial Cells
Lung

Modeling succinate dehydrogenase loss disorders in C. elegans through effects on hypoxia-inducible factor

Braun, M. M., Damjanac, T., Zhang, Y., Chen, C., Hu, J. & Maher, L. J., Jan 1 2019, In : PloS one. 14, 12, e0227033.

Research output: Contribution to journalArticle

Open Access
Succinate Dehydrogenase
hypoxia
Enzymes
enzymes
Mitochondrial Diseases

Molecular characterization of known and novel ACVR1 variants in phenotypes of aberrant ossification

Gupta, A., Zimmermann, M. T., Wang, H., Broski, S. M., Sigafoos, A. N., Macklin, S. K., Urrutia, R. A., Clark, K. J., Atwal, P. S., Pignolo, R. J. & Klee, E. W., Jan 1 2019, In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

Myositis Ossificans
Diffuse Idiopathic Skeletal Hyperostosis
Ligaments
Osteogenesis
Phenotype

Novel role of Tieg1 in muscle metabolism and mitochondrial oxidative capacities

Kammoun, M., Piquereau, J., Nadal-Desbarats, L., Même, S., Beuvin, M., Bonne, G., Veksler, V., Le Fur, Y., Pouletaut, P., Même, W., Szeremeta, F., Constans, J. M., Bruinsma, E. S., Nelson Holte, M. H., Najafova, Z., Johnsen, S. A., Subramaniam, M., Hawse, J. R. & Bensamoun, S. F., Jan 1 2019, (Accepted/In press) In : Acta Physiologica. e13394.

Research output: Contribution to journalArticle

Muscles
Knockout Mice
Citrate (si)-Synthase
Skeletal Muscle
RNA Sequence Analysis
2 Citations (Scopus)

Novel zebrafish behavioral assay to identify modifiers of the rapid, nongenomic stress response

Lee, H. B., Schwab, T. L., Sigafoos, A. N., Gauerke, J. L., Krug, R. G., Serres, M. K. R., Jacobs, D. C., Cotter, R. P., Das, B., Petersen, M. O., Daby, C. L., Urban, R. M., Berry, B. C. & Clark, K. J., Jan 1 2019, (Accepted/In press) In : Genes, Brain and Behavior. e12549.

Research output: Contribution to journalArticle

Zebrafish
Mineralocorticoid Receptors
Exons
Glucocorticoid Receptors
Corticotropin Receptors
3 Citations (Scopus)

Optimization of a 40-mer Antimyelin DNA Aptamer Identifies a 20-mer with Enhanced Properties for Potential Multiple Sclerosis Therapy

Wilbanks, B., Smestad, J., Heider, R. M., Warrington, A. E., Rodriguez, M. & Maher III, L. J., Jun 1 2019, In : Nucleic Acid Therapeutics. 29, 3, p. 126-135 10 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
Myelin Sheath
Multiple Sclerosis
Streptavidin
Nucleotides

Optimized immunohistochemical detection of estrogen receptor beta using two validated monoclonal antibodies confirms its expression in normal and malignant breast tissues

Hawse, J. R., Carter, J. M., Aspros, K. G. M., Bruinsma, E. S., Koepplin, J. W., Negron, V., Subramaniam, M., Ingle, J. N., Rech, K. L. & Goetz, M. P., Jan 1 2019, (Accepted/In press) In : Breast Cancer Research and Treatment.

Research output: Contribution to journalArticle

Estrogen Receptor beta
Breast
Monoclonal Antibodies
Antibodies
Breast Neoplasms
1 Citation (Scopus)

Overcoming EZH2 inhibitor resistance by taxane in PTEN-mutated cancer

Ma, L., Yan, Y., Bai, Y., Yang, Y., Pan, Y., Gang, X., Karnes, R. J., Zhang, J., Lv, Q., Wu, Q. & Huang, H., Jan 1 2019, In : Theranostics. 9, 17, p. 5020-5034 15 p.

Research output: Contribution to journalArticle

Open Access
docetaxel
Prostatic Neoplasms
Neoplasms
Polycomb-Group Proteins
Forkhead Transcription Factors
1 Citation (Scopus)

Phenotyping an adult zebrafish lamp2 cardiomyopathy model identifies mTOR inhibition as a candidate therapy

Dvornikov, A. V., Wang, M., Yang, J., Zhu, P., Le, T., Lin, X., Cao, H. & Xu, X. H., Aug 1 2019, In : Journal of Molecular and Cellular Cardiology. 133, p. 199-208 10 p.

Research output: Contribution to journalArticle

Glycogen Storage Disease Type IIb
Hypertrophic Cardiomyopathy
Zebrafish
Cardiomyopathies
Actomyosin
13 Citations (Scopus)

Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression

Jin, X., Ding, D., Yan, Y., Li, H., Wang, B., Ma, L., Ye, Z., Ma, T., Wu, Q., Rodrigues, D. N., Kohli, M., Jimenez, R. E., Wang, L., Goodrich, D. W., de Bono, J., Dong, H. M., Wu, H., Zhu, R. & Huang, H., Jan 3 2019, In : Molecular Cell. 73, 1, p. 22-35.e6

Research output: Contribution to journalArticle

Immunity
E2F Transcription Factors
Neoplasms
Phosphorylation

Posttranslational regulation of androgen dependent and independent androgen receptor activities in prostate cancer

Wen, S., Niu, Y. & Huang, H., Jan 1 2019, (Accepted/In press) In : Asian Journal of Urology.

Research output: Contribution to journalReview article

Open Access
Androgen Receptors
Androgens
Prostatic Neoplasms
Post Translational Protein Processing
Castration

Recommendations for performance optimizations when using GATK3.8 and GATK4

Heldenbrand, J. R., Baheti, S., Bockol, M. A., Drucker, T. M., Hart, S. N., Hudson, M. E., Iyer, R. K., Kalmbach, M. T., Kendig, K. I., Klee, E. W., Mattson, N. R., Wieben, E. D., Wiepert, M., Wildman, D. E. & Mainzer, L. S., Nov 8 2019, In : BMC bioinformatics. 20, 1, 557.

Research output: Contribution to journalArticle

Open Access
Performance Optimization
Recommendations
Genes
Cost effectiveness
Electric sparks
2 Citations (Scopus)

RINT1 Bi-allelic Variations Cause Infantile-Onset Recurrent Acute Liver Failure and Skeletal Abnormalities

Cousin, M. A., Conboy, E., Wang, J. S., Lenz, D., Schwab, T. L., Williams, M., Abraham, R. S., Barnett, S., El-Youssef, M., Graham, R. P., Gutierrez Sanchez, L. H., Hasadsri, L., Hoffmann, G. F., Hull, N. C., Kopajtich, R., Kovacs-Nagy, R., Li, J. Q., Marx-Berger, D., McLin, V., McNiven, M. A. & 9 others, Mounajjed, T., Prokisch, H., Rymen, D., Schulze, R. J., Staufner, C., Yang, Y., Clark, K. J., Lanpher, B. C. & Klee, E. W., Jul 3 2019, In : American journal of human genetics. 105, 1, p. 108-121 14 p.

Research output: Contribution to journalArticle

Acute Liver Failure
Liver
Autophagy
Fibroblasts
Transport Vesicles
1 Citation (Scopus)

RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis

Bai, Y., Yang, Y., Yan, Y., Zhong, J., Blee, A. M., Pan, Y., Ma, T., Karnes, R. J., Jimenez, R. E., Xu, W. & Huang, H., Jan 1 2019, In : Theranostics. 9, 12, p. 3459-3475 17 p.

Research output: Contribution to journalArticle

Open Access
Haploinsufficiency
Prostate
Prostatic Neoplasms
Carcinogenesis
Phosphorylation
2 Citations (Scopus)

SentIeon DNaSeq variant calling workflow demonstrates strong computational performance and accuracy

Kendig, K. I., Baheti, S., Bockol, M. A., Drucker, T. M., Hart, S., Heldenbrand, J. R., Hernaez, M., Hudson, M. E., Kalmbach, M. T., Klee, E. W., Mattson, N. R., Ross, C. A., Taschuk, M., Wieben, E. D., Wiepert, M., Wildman, D. E. & Mainzer, L. S., Jan 1 2019, In : Frontiers in Genetics. 10, JUL, 736.

Research output: Contribution to journalArticle

Open Access
Workflow
Genome
Software

Serial Block Face SEM Service

Salisbury, J. L., Sanders, M., Charlesworth, J., Christensen, T. & Jaspersen, A., Dec 1 2019, In : Journal of biomolecular techniques : JBT. 30, p. S60

Research output: Contribution to journalArticle

Organelles
Names
Research Personnel
Electrons
Cell Polarity