Biochemistry and Molecular Biology

Projects 1975 2021

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Research project
Pancreatic Neoplasms
Phosphotransferases
Lipids
Neoplasms

DNS SEQUENCES IN NUCLEAR BINDING OF PROGESTERONE

Spelsberg, T. C.

National Institutes of Health

7/1/8212/31/86

Project: Research project

progesterone
DNA
nucleotide sequences
proteins
nucleases
Fuchs' Endothelial Dystrophy
Trinucleotide Repeat Expansion
Transcription Factors
Corneal Endothelium
Disease Progression
Morphogenesis
Breast
Neoplasm Metastasis
Cell-Matrix Junctions
Cell Movement
Electrostatic force
DNA
Proteins
proteins
phosphates

Differences in the Reaction Cycle among PMCA Isoforms

Strehler, E. E.

National Institutes of Health

4/1/053/31/10

Project: Research project

Protein Isoforms
Cell Membrane
Calcium
Cations
Ions
RNA
Ligands
DNA
Bacteriophage T7
Nucleic Acids

Visualizing Actomyosin Transients by Data Merging

Burghardt, T. P.

National Institutes of Health

12/1/026/30/15

Project: Research project

Actomyosin
Myosins
Merging
Adenosine Triphosphate
Conformations

MOLECULAR ANGLE TRANSITIONS IN MUSCLE

Burghardt, T. P.

National Institutes of Health

1/1/906/30/03

Project: Research project

muscles
Muscle
probes
muscle fibers
electron paramagnetic resonance
centrosomes
germ cells
spermatozoa
calcium-binding proteins
spermatocytes
Myosins
Hypertrophy
Myosin Heavy Chains
Familial Hypertrophic Cardiomyopathy
Mutation

PROPERTIES OF CALCIUM PUMPING ATPASE

Strehler, E. E. & Penniston, J.

National Institutes of Health

8/1/801/31/08

Project: Research project

Calcium-Transporting ATPases
Calcium
Ions
Protein Isoforms
Calmodulin
Chromosome Breakage
DNA Breaks
Ubiquitin
Histones
Homologous Recombination
Endosomal Sorting Complexes Required for Transport
Multivesicular Bodies
Ubiquitin
Cytokinesis
Hereditary Spastic Paraplegia
Androgen Receptors
Prostatic Neoplasms
Androgens
Castration
Interleukin-6
NF-kappa B
Genetic Selection
DNA-Binding Proteins
Yeasts
Nucleotide Aptamers

MULTIDISCIPLINARY BASIC RESEARCH TRAINING IN CANCER

Smith, D. I., Salisbury, J. L., Getz, M. J., Scott, R. & Getz, M. J.

National Institutes of Health

6/1/833/31/04

Project: Research project

Research
Neoplasms
Molecular Biology
Medicine Chests
Animal Housing
Frizzled Receptors
Embryonic Development
Genes
Zebrafish
Xenopus
Sarcomeres
Heart Diseases
Connectin
Cardiomyopathies
Zebrafish

MODE OF ACTION OF REPRODUCTIVE HORMONES

Wieben, E. D., David, C. S., Spelsberg, T. C., Tindall, D. J., Spelsberg, T. C., Pendergast, F., Tindall, D. J., Roche, P., Pendergast, F., Penniston, J., Ryan, R., Roche, P., Toft, D., Tindall, D. J., Tindall, D. J. & Mc Cormick, D. J.

National Institutes of Health

5/1/753/31/02

Project: Research project

Oviducts
Progesterone Receptors
Chromatin
LH Receptors
Monoclonal Antibodies
Multivesicular Bodies
Endosomal Sorting Complexes Required for Transport
Membranes
Liddle Syndrome
Growth Factor Receptors
Transforming Growth Factor beta
Steroids
Bone and Bones
Genes
Estrogen Receptor beta
nucleic acid
RNA
DNA

Membrane Targeting of Calcium-Pumping ATPase

Strehler, E. E.

National Institutes of Health

3/1/072/28/12

Project: Research project

Plasma Membrane Calcium-Transporting ATPases
Calcium-Transporting ATPases
Membranes
Neurons
Protein Isoforms

REGULATION OF THE PLASMA MEMBRANE CALCIUM ATPASE

Strehler, E. E.

National Institutes of Health

2/1/991/31/04

Project: Research project

Plasma Membrane Calcium-Transporting ATPases
Calcium-Transporting ATPases
Cell Membrane
Protein Isoforms
Proteins
DNA Damage
Histones
Lysine
Methylation
Post Translational Protein Processing
Paraganglioma
Dioxygenases
Neoplasms
Neuroendocrine Cells
Caenorhabditis elegans
temozolomide
Drug Resistance
Histones
Phosphorylation
Glioblastoma
Nanoconjugates
gemcitabine
Gold
Nanoparticles
Pancreatic Neoplasms

Cell Surface Receptor Trafficking

Horazdovsky, B. F.

National Institutes of Health

7/1/036/30/07

Project: Research project

Cell Surface Receptors
Proteins
Endocytosis
Guanosine Triphosphate
Guanine Nucleotide Exchange Factors
insertional mutagenesis
Zebrafish
Introns
Danio rerio
transposons
Zebrafish Proteins
Zebrafish
Vertebrates
Genome
Proteome
Centrosome
Breast Neoplasms
Hypertrophy
Centrioles
Microtubules
Contractile Proteins
Cell Biology
Carrier Proteins
Calcium-Binding Proteins
Eukaryotic Cells

ROLE OF A TGF-BETA REGULATED GENE IN HUMAN OSTEOBLASTS

Spelsberg, T. C., Hawse, J. R., Subramaniam, M. & Hawse, J. R.

National Institutes of Health

9/1/016/30/17

Project: Research project

Osteoblasts
Skeleton
Genes
Transforming Growth Factor beta
Wnt Signaling Pathway
Phosphoproteins
Tandem Repeat Sequences
Phosphopeptides
Proteins
Histones
Zebrafish
Nicotine
Glucocorticoid Receptors
Homeostasis
Vertebrates

Bmi-1, a potential therapeutic target in ovarian cancer

Bhattacharya, R. D.

National Institutes of Health

9/7/126/30/17

Project: Research project

Ovarian Neoplasms
Cisplatin
Apoptosis
Small Interfering RNA
Neoplasms
Cilia
Dissection
Genes
Basal Bodies
Centrioles

CANCER CENTER SUPPORT GRANT (COMPREHENSIVE)

David, C. S., Jenkins, R. B., Cunningham, J. M., Wettstein, P. J., Buckner, J. C., Lingle, W. L., Kocher, J., Highsmith, W. E. J., Beebe, T. J., Vile, R. G., Okuno, S. H., Sarkaria, J. N., Alberts, S. R., Salisbury, J. L., Van Deursen, J., Diasio, R. B., Sargent, D. J., Thibodeau, S. N., Ingle, J. N., Reid, J. M., Colon-Otero, G., Galanis, E., Weinshilboum, R. M., Jenkins, R. B., Banks, P., Flotte, T., Kwon, E. D., Federspiel, M. J., Pitot, H. C., Dewald, G., Held, K., Liebson, P., Banks, P., Prendergast, F., Weiland, L., Wiebeu, E., Moertel, C., Clapham, D., Burnham, N., O'Connell, M., Spelsburg, T., Maihle, N., Katzmann, J., Wieand, H., Kovach, J., Wold, L., Grendahl, D., McCormick, D., Leibson, P., O'Fallon, J., Ames, M., Kline, B., Prendergast, F., Adjei, A., Chute, C., McKean, D., Highsmith, E., Raghavakaimal, S., Pitot, H., Greipp, P., Wieben, E., Roche, P., Leibson, P., Lawson, M., Grendahl, D., McCormick, D., Ames, M., Wieben, E. D., Flotte, T. J., Adjei, A. & Greipp, P. T.

National Institutes of Health

3/1/802/28/19

Project: Research project

Neoplasms
Research
Research Personnel
Cytogenetics
Biostatistics
Long Noncoding RNA
Erythrocytes
RNA
Biomedical Research
Anemia

PROTEIN LOCALIZATION OF THE YEAST VACUOLE

Horazdovsky, B. F.

National Institutes of Health

6/1/974/30/08

Project: Research project

vacuoles
yeasts
protein transport
Protein Transport
Vacuoles
X Chromosome Inactivation
Origin Recognition Complex
Epigenomics
Maintenance
Untranslated RNA

Cystathionine beta synthase (CBS) and angiogenesis

Mukherjee, P. H. & Bhattacharya, R. D.

National Institutes of Health

8/15/136/30/18

Project: Research project

Cystathionine beta-Synthase
Homocysteine
Homocystinuria
Cystathionine
Methionine
Cilia
Monomeric GTP-Binding Proteins
ADP-Ribosylation Factors
Caenorhabditis elegans
Ciliopathies
Nucleosomes
Histones
DNA Replication
Acetylation
Genomic Instability

BONE CELL PROTO-ONCOGENE PROMOTERS

Spelsberg, T. C.

National Institutes of Health

7/10/925/31/97

Project: Research project

Proto-Oncogenes
Bone and Bones
Transforming Growth Factor beta
Osteoclasts
Osteoblasts

NOVEL TGF-BETA INDUCIBLE GENE IN HUMAN OSTEOBLASTS

Spelsberg, T. C.

National Institutes of Health

7/5/966/30/99

Project: Research project

Osteoblasts
Transforming Growth Factor beta
Genes
Proteins
Bone and Bones
Antigens
Proteins
Systemic Lupus Erythematosus
Connective Tissue Diseases
Antibodies
Zebrafish
Cardiomyopathies
Sirolimus
Autophagy
Modifier Genes