Biochemistry and Molecular Biology

Projects 1975 2021

A COMPONENT INVOLVED IN YEAST VACUOLAR PROTEIN SORTING

Horazdovsky, B. F., Harris, T. M. & Harris, T. M.

National Institutes of Health

5/1/77 → …

Project: Research project

A NEW CLASS OF EPSTEIN BARR VIRUS NUCLEAR ANTIGEN

Spelsberg, T. C.

National Institutes of Health

4/1/7912/31/85

Project: Research project

Epstein-Barr Virus Nuclear Antigens
Histones
Isoelectric Focusing
Acetylation
Chromatin

Bmi-1, a potential therapeutic target in ovarian cancer

Bhattacharya, R. D.

National Institutes of Health

9/7/126/30/17

Project: Research project

Ovarian Neoplasms
Cisplatin
Apoptosis
Small Interfering RNA
Neoplasms

BONE CELL PROTO-ONCOGENE PROMOTERS

Spelsberg, T. C.

National Institutes of Health

7/10/925/31/97

Project: Research project

Proto-Oncogenes
Bone and Bones
Transforming Growth Factor beta
Osteoclasts
Osteoblasts

CANCER CENTER SUPPORT GRANT (COMPREHENSIVE)

David, C. S., Jenkins, R. B., Cunningham, J. M., Wettstein, P. J., Buckner, J. C., Lingle, W. L., Kocher, J., Highsmith, W. E. J., Beebe, T. J., Vile, R. G., Okuno, S. H., Sarkaria, J. N., Alberts, S. R., Salisbury, J. L., Van Deursen, J., Diasio, R. B., Sargent, D. J., Thibodeau, S. N., Ingle, J. N., Reid, J. M., Colon-Otero, G., Galanis, E., Weinshilboum, R. M., Jenkins, R. B., Banks, P., Flotte, T., Kwon, E. D., Federspiel, M. J., Pitot, H. C., Dewald, G., Held, K., Liebson, P., Banks, P., Prendergast, F., Weiland, L., Wiebeu, E., Moertel, C., Clapham, D., Burnham, N., O'Connell, M., Spelsburg, T., Maihle, N., Katzmann, J., Wieand, H., Kovach, J., Wold, L., Grendahl, D., McCormick, D., Leibson, P., O'Fallon, J., Ames, M., Kline, B., Prendergast, F., Adjei, A., Chute, C., McKean, D., Highsmith, E., Raghavakaimal, S., Pitot, H., Greipp, P., Wieben, E., Roche, P., Leibson, P., Lawson, M., Grendahl, D., McCormick, D., Ames, M., Wieben, E. D., Flotte, T. J., Adjei, A. & Greipp, P. T.

National Institutes of Health

3/1/802/28/19

Project: Research project

Neoplasms
Research
Research Personnel
Cytogenetics
Biostatistics

Cell Surface Receptor Trafficking

Horazdovsky, B. F.

National Institutes of Health

7/1/036/30/07

Project: Research project

Cell Surface Receptors
Proteins
Endocytosis
Guanosine Triphosphate
Guanine Nucleotide Exchange Factors
centrosomes
germ cells
spermatozoa
calcium-binding proteins
spermatocytes
Centrosome
Breast Neoplasms
Hypertrophy
Centrioles
Microtubules
RNA
Ligands
DNA
Bacteriophage T7
Nucleic Acids

Cystathionine beta synthase (CBS) and angiogenesis

Mukherjee, P. H. & Bhattacharya, R. D.

National Institutes of Health

8/15/136/30/18

Project: Research project

Cystathionine beta-Synthase
Homocysteine
Homocystinuria
Cystathionine
Methionine
Pancreatic Neoplasms
Phosphotransferases
Lipids
Neoplasms
Zebrafish
Nicotine
Glucocorticoid Receptors
Homeostasis
Vertebrates
Nanoconjugates
gemcitabine
Gold
Nanoparticles
Pancreatic Neoplasms

Differences in the Reaction Cycle among PMCA Isoforms

Strehler, E. E.

National Institutes of Health

4/1/053/31/10

Project: Research project

Protein Isoforms
Cell Membrane
Calcium
Cations
Ions
Zebrafish
Cardiomyopathies
Sirolimus
Autophagy
Modifier Genes

DNS SEQUENCES IN NUCLEAR BINDING OF PROGESTERONE

Spelsberg, T. C.

National Institutes of Health

7/1/8212/31/86

Project: Research project

progesterone
DNA
nucleotide sequences
proteins
nucleases
Electrostatic force
DNA
Proteins
proteins
phosphates
HMGB Proteins
DNA
Polymers
Proteins
Yeasts
Cilia
Monomeric GTP-Binding Proteins
ADP-Ribosylation Factors
Caenorhabditis elegans
Ciliopathies
Prostatic Neoplasms
DNA Damage
Prostate
Carcinogenesis
Phosphorylation
Frizzled Receptors
Embryonic Development
Genes
Zebrafish
Xenopus

Function of CAF-1 in Epigenetic Inheritance

Zhang, Z. H.

National Institutes of Health

9/20/058/31/19

Project: Research project

Epigenomics
Histone Chaperones
Nucleosomes
Chromatin
Histones
Sarcomeres
Heart Diseases
Connectin
Cardiomyopathies
Zebrafish
Nucleosomes
Histones
DNA Replication
Acetylation
Genomic Instability
X Chromosome Inactivation
Origin Recognition Complex
Epigenomics
Maintenance
Untranslated RNA
insertional mutagenesis
Zebrafish
Introns
Danio rerio
transposons
Myosins
Hypertrophy
Myosin Heavy Chains
Familial Hypertrophic Cardiomyopathy
Mutation
Zebrafish Proteins
Zebrafish
Vertebrates
Genome
Proteome
Gastroenterology
Research
Technology
Research Personnel
Microscopy
Research Personnel
Research
Organized Financing
Autosomal Dominant Polycystic Kidney
Zebrafish
Androgen Receptors
Prostatic Neoplasms
Androgens
Castration
Interleukin-6
Multivesicular Bodies
Endosomal Sorting Complexes Required for Transport
Membranes
Liddle Syndrome
Growth Factor Receptors

Mechanisms of Epigenetic inheritance

Zhang, Z. H.

National Institutes of Health

9/1/167/31/21

Project: Research project

Nucleosomes
DNA Replication
Epigenomics
Histones
Yeasts

Membrane Targeting of Calcium-Pumping ATPase

Strehler, E. E.

National Institutes of Health

3/1/072/28/12

Project: Research project

Plasma Membrane Calcium-Transporting ATPases
Calcium-Transporting ATPases
Membranes
Neurons
Protein Isoforms

MODE OF ACTION OF REPRODUCTIVE HORMONES

Wieben, E. D., David, C. S., Spelsberg, T. C., Tindall, D. J., Spelsberg, T. C., Pendergast, F., Tindall, D. J., Roche, P., Pendergast, F., Penniston, J., Ryan, R., Roche, P., Toft, D., Tindall, D. J., Tindall, D. J. & Mc Cormick, D. J.

National Institutes of Health

5/1/753/31/02

Project: Research project

Oviducts
Progesterone Receptors
Chromatin
LH Receptors
Monoclonal Antibodies

MOLECULAR ANGLE TRANSITIONS IN MUSCLE

Burghardt, T. P.

National Institutes of Health

1/1/906/30/03

Project: Research project

muscles
Muscle
probes
muscle fibers
electron paramagnetic resonance
Paraganglioma
Dioxygenases
Neoplasms
Neuroendocrine Cells
Caenorhabditis elegans
Contractile Proteins
Cell Biology
Carrier Proteins
Calcium-Binding Proteins
Eukaryotic Cells
Cilia
Dissection
Genes
Basal Bodies
Centrioles
Gold
Nanoparticles
Intercellular Signaling Peptides and Proteins
Heparin
Ovarian Neoplasms

MULTIDISCIPLINARY BASIC RESEARCH TRAINING IN CANCER

Smith, D. I., Salisbury, J. L., Getz, M. J., Scott, R. & Getz, M. J.

National Institutes of Health

6/1/833/31/04

Project: Research project

Research
Neoplasms
Molecular Biology
Medicine Chests
Animal Housing

NOVEL TGF-BETA INDUCIBLE GENE IN HUMAN OSTEOBLASTS

Spelsberg, T. C.

National Institutes of Health

7/5/966/30/99

Project: Research project

Osteoblasts
Transforming Growth Factor beta
Genes
Proteins
Bone and Bones
nucleic acid
RNA
DNA
Breast Neoplasms
Research Personnel
Research
Biostatistics
Translational Medical Research

Pathobiology of Diabetic Gastroenteropathy

Ordog, T., Robb, R. A., Bharucha, A. E., Szurszewski, J. H., Farrugia, G., Linden, D. R., Zhang, Z., Zhang, Z. H., Vernino, S., Jeong-Heon, L., Lee, J. H. & Bharucha, A. E.

National Institutes of Health

7/1/046/30/20

Project: Research project

Gastric Emptying
Stomach
Interstitial Cells of Cajal
Gastroparesis
Glucagon-Like Peptide 1