Biochemistry and Molecular Biology

Research Output

Article

Intravitreal alemtuzumab penetrates full-thickness retina in rabbit eyes

Ekdawi, N. S., Pulido, J. S., Itty, S., Marler, R. J., Herman, D. C., Hardwig, P., Mohney, B. G., Valyi-Nagy, T. & Shukla, D., Nov 2009, In : Retina. 29, 10, p. 1532-1534 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Intrinsic AHR in IL-5 transgenic mice is dependent on C4+ cells and CD49d-mediated signaling

Borchers, M. T., Crosby, J., Justice, P., Farmer, S., Hines, E., Lee, J. J. & Lee, N. A., 2001, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 281, 3 25-3

Research output: Contribution to journalArticle

17 Scopus citations

In vitro assessment of chemokine receptor-ligand interactions mediating mouse eosinophil migration

Borchers, M. T., Ansay, T., DeSalle, R., Daugherty, B. L., Shen, H., Metzger, M., Lee, N. A. & Lee, J. J., Jun 1 2002, In : Journal of Leukocyte Biology. 71, 6, p. 1033-1041 9 p.

Research output: Contribution to journalArticle

73 Scopus citations

In vitro kinetic analysis of cellular anti-MUC1 immune responses in MUC1 transgenic mice

VanLith, M. L., Tempero, R. M., Gendler, S. J. & Hollingsworth, M. A., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

In vivo radioiodide imaging and treatment of breast cancer xenografts after MUC1-driven expression of the sodium iodide symporter

Dwyer, R. M., Bergert, E. R., O'Connor, M. K., Gendler, S. J. & Morris, J. C., Feb 15 2005, In : Clinical Cancer Research. 11, 4, p. 1483-1489 7 p.

Research output: Contribution to journalArticle

74 Scopus citations

Lack of eosinophil peroxidase or major basic protein impairs defense against murine filarial infection

Specht, S., Saeftel, M., Arndt, M., Endl, E., Dubben, B., Lee, N. A., Lee, J. J. & Hoerauf, A., Sep 2006, In : Infection and Immunity. 74, 9, p. 5236-5243 8 p.

Research output: Contribution to journalArticle

61 Scopus citations

Lack of muc1-regulated β-catenin stability results in aberrant expansion of cd11b +gr1 + Myeloid-derived suppressor cells from the bone marrow

Poh, T. W., Bradley, J. M., Mukherjee, P. & Gendler, S. J., Apr 15 2009, In : Cancer Research. 69, 8, p. 3554-3562 9 p.

Research output: Contribution to journalArticle

25 Scopus citations
20 Scopus citations

Lactam constraints provide insights into the receptor-bound conformation of secretin and stabilize a receptor antagonist

Dong, M., Te, J. A., Xu, X., Wang, J., Pinon, D. I., Storjohann, L., Bordner, A. J. & Miller, L. J., Sep 27 2011, In : Biochemistry. 50, 38, p. 8181-8192 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Letter for Joyce

Gendler, S. J., Nov 2001, In : Glycoconjugate Journal. 18, 11-12, p. 839-840 2 p.

Research output: Contribution to journalArticle

Ligand binding and activation of the secretin receptor, a prototypic family B G protein-coupled receptor

Miller, L. J., Dong, M. & Harikumar, K. G., May 2012, In : British Journal of Pharmacology. 166, 1, p. 18-26 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Ligand binding to integrins

Plow, E. F., Haas, T. A., Zhang, L., Loftus, J. C. & Smith, J. W., Jul 21 2000, In : Journal of Biological Chemistry. 275, 29, p. 21785-21788 4 p.

Research output: Contribution to journalArticle

996 Scopus citations
2 Scopus citations

Linear synthesis and immunological properties of a fully synthetic vaccine candidate containing a sialylated MUC1 glycopeptide

Thompson, P., Lakshminarayanan, V., Supekar, N. T., Bradley, J. M., Cohen, P. A., Wolfert, M. A., Gendler, S. J. & Boons, G. J., May 28 2015, In : Chemical Communications. 51, 50, p. 10214-10217 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis

Masterson, J. C., McNamee, E. N., Hosford, L., Capocelli, K. E., Ruybal, J., Fillon, S. A., Doyle, A. D., Eltzschig, H. K., Rustgi, A. K., Protheroe, C. A., Lee, N. A., Lee, J. J. & Furuta, G. T., Jan 2014, In : Gut. 63, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Local proliferation and mobilization of CCR3+ CD34+ eosinophil-lineage-committed cells in the lung

Rådinger, M., Bossios, A., Sjöstrand, M., Lu, Y., Malmhäll, C., Dahlborn, A. K., Lee, J. J. & Lötvall, J., Jan 2011, In : Immunology. 132, 1, p. 144-154 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Longevity and age-related pathology of mice deficient in pregnancy-associated plasma protein-a

Conover, C. A., Bale, L. K., Mader, J. R., Mason, M. A., Keenan, K. P. & Marler, R. J., Jun 2010, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 65 A, 6, p. 590-599 10 p.

Research output: Contribution to journalArticle

57 Scopus citations

Loss of heterozygosity analysis in primary mammary tumors and lung metastases of MMTV-MTAg and MMTV-neu transgenic mice

Ritland, S. R., Rowse, G. J., Chang, Y. & Gendler, S. J., Aug 15 1997, In : Cancer Research. 57, 16, p. 3520-3525 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Low-Dose Gamma Irradiation of Decellularized Heart Valves Results in Tissue Injury In Vitro and In Vivo

Helder, M. R. K., Hennessy, R. S., Spoon, D. B., Tefft, B. J., Witt, T. A., Marler, R. J., Pislaru, S. V., Simari, R. D., Stulak, J. M. & Lerman, A., 2015, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

9 Scopus citations

Lung pathologies in a chronic inflammation mouse model are independent of eosinophil degranulation

Jacobsen, E., Ochkur, S. I., Doyle, A. D., LeSuer, W. E., Li, W., Protheroe, C. A., Colbert, D., Zellner, K. R., Shen, H. H., Irvin, C. G., Lee, J. J. & Lee, N. A., May 15 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 10, p. 1321-1332 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Major basic protein-1 promotes fibrosis of dystrophic muscle and attenuates the cellular immune response in muscular dystrophy

Wehling-henricks, M., Sokolow, S., Lee, J. J., Myung, K. H., Villalta, S. A. & Tidball, J. G., Aug 2008, In : Human Molecular Genetics. 17, 15, p. 2280-2292 13 p.

Research output: Contribution to journalArticle

50 Scopus citations

Many αIIbβ3 autoepitopes in chronic immune thrombocytopenic purpura are localized to αIIb between amino acids L1 and Q459

Mcmillan, R., Wang, L., Lopez-Dee, J., Jiu, S. & Loftus, J. C., 2002, In : British Journal of Haematology. 118, 4, p. 1132-1136 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Mapping of cystic fibrosis transmembrane conductance regulator membrane topology by glycosylation site insertion

Chang, X-B. D., Hou, Y. X., Jensen, T. J. & Riordan, J. R., Jul 15 1994, In : Journal of Biological Chemistry. 269, 28, p. 18572-18575 4 p.

Research output: Contribution to journalArticle

113 Scopus citations
4 Scopus citations

Mast cells are required for full expression of allergen/SEB-Induced skin inflammation

Ando, T., Matsumoto, K., Namiranian, S., Yamashita, H., Glatthorn, H., Kimura, M., Dolan, B. R., Lee, J. J., Galli, S. J., Kawakami, Y., Jamora, C. & Kawakami, T., Dec 2013, In : Journal of Investigative Dermatology. 133, 12, p. 2695-2705 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
21 Scopus citations

Mechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cells.

Basu, G. D., Pathangey, L. B., Tinder, T. L., Gendler, S. J. & Mukherjee, P., 2005, In : Breast cancer research : BCR. 7, 4

Research output: Contribution to journalArticle

115 Scopus citations

Membrane cholesterol affects stimulus-activity coupling in type 1, but not type 2, CCK receptors: Use of cell lines with elevated cholesterol

Harikumar, K. G., Potter, R. M., Patil, A., Echeveste, V. & Miller, L. J., Mar 2013, In : Lipids. 48, 3, p. 231-244 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction

Blackburn, M. R., Volmer, J. B., Thrasher, J. L., Zhong, H., Crosby, J. R., Lee, J. J. & Kellems, R. E., Jul 17 2000, In : Journal of Experimental Medicine. 192, 2, p. 159-170 12 p.

Research output: Contribution to journalArticle

183 Scopus citations

Methacholine-induced airway hyperresponsiveness is dependent on Gαq signaling

Borchers, M. T., Biechele, T., Justice, J. P., Ansay, T., Cormier, S., Mancino, V., Wilkie, T. M., Simon, M. I., Lee, N. A. & Lee, J. J., Jul 1 2003, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 285, 1 29-1

Research output: Contribution to journalArticle

18 Scopus citations

Methylprednisolone acetate induces, and ?7-dafachronic acid suppresses, Strongyloides stercoralis hyperinfection in NSG mice

Patton, J. B., Bonne-Année, S., Deckman, J., Hess, J. A., Torigian, A., Nolan, T. J., Wang, Z., Kliewer, S. A., Durham, A. C., Lee, J. J., Eberhard, M. L., Mangelsdorf, D. J., Lok, J. B. & Abraham, D., Jan 2 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 1, p. 204-209 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy

Mader, J. R., Resch, Z. T., McLean, G. R., Mikkelsen, J. H., Oxvig, C., Marler, R. J. & Conover, C. A., 2013, In : Journal of Endocrinology. 219, 1, p. 51-58 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
75 Scopus citations

Mimic 1 of MUC1

Finn, O. J. & Gendler, S. J., 1998, In : Nature Biotechnology. 16, 3, p. 236-237 2 p.

Research output: Contribution to journalArticle

5 Scopus citations
47 Scopus citations

Misassembled mutant ΔF508 CFTR in the distal secretory pathway alters cellular lipid trafficking

Gentzsch, M., Choudhury, A., Chang, X-B. D., Pagano, R. E. & Riordan, J. R., Feb 1 2007, In : Journal of Cell Science. 120, 3, p. 447-455 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Modulation of cell surface expression of nonactivated cholecystokinin receptors using bivalent ligand-induced internalization

Harikumar, K. G., Akgün, E., Portoghese, P. S. & Miller, L. J., Apr 8 2010, In : Journal of Medicinal Chemistry. 53, 7, p. 2836-2842 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Modulation of Muc-1 mucin expression in the mouse uterus during the estrus cycle, early pregnancy and placentation

Braga, V. M. M. & Gendler, S. J., Jun 1993, In : Journal of Cell Science. 105, 2, p. 397-405 9 p.

Research output: Contribution to journalArticle

127 Scopus citations

Modulation of β-catenin signaling by glucagon receptor activation

Ke, J., Zhang, C., Harikumar, K. G., Zylstra-Diegel, C. R., Wang, L., Mowry, L. E., Miller, L. J., Williams, B. O. & Xu, H. E., Mar 16 2012, In : PLoS One. 7, 3, e33676.

Research output: Contribution to journalArticle

13 Scopus citations

Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: Identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G)

Aizawa, H., Zimmermann, N., Carrigan, P. E., Lee, J. J., Rothenberg, M. E. & Bochner, B. S., Nov 1 2003, In : Genomics. 82, 5, p. 521-530 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Molecular basis for benzodiazepine agonist action at the type 1 cholecystokinin receptor

Harikumar, K. G., Cawston, E. E., Lam, P. C. H., Patil, A., Orry, A., Henke, B. R., Abagyan, R., Christopoulos, A., Sexton, P. M. & Miller, L. J., Jul 19 2013, In : Journal of Biological Chemistry. 288, 29, p. 21082-21095 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Molecular basis for binding and subtype selectivity of 1,4-benzodiazepine antagonist ligands of the cholecystokinin receptor

Cawston, E. E., Lam, P. C. H., Harikumar, K. G., Dong, M., Ball, A. M., Augustine, M. L., Akgün, E., Portoghese, P. S., Orry, A., Abagyan, R., Sexton, P. M. & Miller, L. J., May 25 2012, In : Journal of Biological Chemistry. 287, 22, p. 18618-18635 18 p.

Research output: Contribution to journalArticle

14 Scopus citations

Molecular basis of association of receptor activity-modifying protein 3 with the family B G protein-coupled secretin receptor

Harikumar, K. G., Simms, J., Christopoulos, G., Sexton, P. M. & Miller, L. J., Dec 15 2009, In : Biochemistry. 48, 49, p. 11773-11785 13 p.

Research output: Contribution to journalArticle

37 Scopus citations

Molecular basis of metastasis [8]

Lee, J. J. & Lotze, M. T., Apr 16 2009, In : New England Journal of Medicine. 360, 16, p. 1679 1 p.

Research output: Contribution to journalArticle

9 Scopus citations

Molecular characterization of the large heavily glycosylated domain glycopeptide from the rat small intestinal Muc2 mucin

Karlsson, N. G., Johansson, M. E., Asker, N., Karlsson, H., Gendler, S. J., Carlstedt, I. & Hansson, G. C., 1996, In : Glycoconjugate Journal. 13, 5, p. 823-831 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
106 Scopus citations