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Dive into the research topics where Steven M Sine is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Structure and Function of the Acetylcholine Receptor
National Institute of Neurological Disorders and Stroke
9/1/92 → 4/30/24
Project: Research project
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Mechanism of calcium potentiation of alpha7 nicotinic receptors
National Institute of Neurological Disorders and Stroke
7/1/16 → 6/30/21
Project: Research project
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Nicotinic receptors in airway disease
Borkar, N. A., Thompson, M. A., Bartman, C. M., Khalfaoui, L., Sine, S., Sathish, V., Prakash, Y. S. & Pabelick, C. M., Feb 2024, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 326, 2, p. L149-L163Research output: Contribution to journal › Review article › peer-review
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Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor
Mazzaferro, S., Kang, G., Natarajan, K., Hibbs, R. E. & Sine, S. M., 2024, (Accepted/In press) In: British Journal of Pharmacology.Research output: Contribution to journal › Article › peer-review
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Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation
Burke, S. M., Avstrikova, M., Noviello, C. M., Mukhtasimova, N., Changeux, J. P., Thakur, G. A., Sine, S. M., Cecchini, M. & Hibbs, R. E., Feb 29 2024, In: Cell. 187, 5, p. 1160-1176.e21Research output: Contribution to journal › Article › peer-review
Open Access -
Functional a7 nicotinic receptors in human airway smooth muscle increase intracellular calcium concentration and contractility in asthmatics
Khalfaoui, L., Mukhtasimova, N., Kelley, B., Wells, N., Teske, J. J., Roos, B. B., Borkar, N. A., Zhang, E. Y., Sine, S. M., Prakash, Y. S. & Pabelick, C. M., Jul 2023, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 325, 1, p. L17-L29Research output: Contribution to journal › Article › peer-review
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Impact on AChR open channel noise by pore-peripheral salt bridge depends on voltage and divalent cations
Strikwerda, J. R., Natarajan, K. & Sine, S. M., Jun 20 2023, In: Biophysical Journal. 122, 12, p. 2430-2444 15 p.Research output: Contribution to journal › Article › peer-review