Projects per year
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Collaborations and top research areas from the last five years
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Investigating the role of TMEM106b genetics and pathology in Alzheimer’s disease, LATE and FTLD
Petrucelli, L. & Josephs, K. A.
National Institute of Neurological Disorders and Stroke
9/22/23 → 8/31/24
Project: Research project
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Discovery of novel TDP-43 splicing targets: the Achilles heel for FTD and towards sensitive biomarkers and therapeutic targets
Gitler, A. D., Fratta, P., Petrucelli, L., Prudencio, M., Prudencio, M. M. & Seeley, W. W.
9/15/21 → 8/31/24
Project: Research project
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Mayo Alzheimer's Disease Research Center
Petersen, R. R. C., Boeve, B. F., Bu, G. D., Dickson, D. W., Kantarci, K. M., Knopman, D. S., Kremers, W. K., Petrucelli, L. & Lucas, J. A.
7/1/19 → 4/30/24
Project: Research project
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The mechanism by which loss of stathmin-2 induces neurodegeneration in ALS
Koike, Y. Y. & Petrucelli, L.
1/31/21 → 1/30/23
Project: Research project
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Artificial microRNA suppresses C9ORF72 variants and decreases toxic dipeptide repeat proteins in vivo
Cabrera, G. T., Meijboom, K. E., Abdallah, A., Tran, H., Foster, Z., Weiss, A., Wightman, N., Stock, R., Gendron, T., Gruntman, A., Giampetruzzi, A., Petrucelli, L., Brown, R. H. & Mueller, C., Mar 2024, In: Gene Therapy. 31, 3-4, p. 105-118 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Clinicopathologic features of a novel star-shaped transactive response DNA-binding protein 43 (TDP-43) pathology in the oldest old
Carlos, A. F., Sekiya, H., Koga, S., Gatto, R. G., Casey, M. C., Pham, N. T. T., Sintini, I., Machulda, M. M., Jack, C. R., Lowe, V. J., Whitwell, J. L., Petrucelli, L., Reichard, R. R., Petersen, R. C., Dickson, D. W. & Josephs, K. A., Jan 1 2024, In: Journal of Neuropathology and Experimental Neurology. 83, 1, p. 36-52 17 p.Research output: Contribution to journal › Article › peer-review
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Erratum: Neurofilament light chain and vaccination status associate with clinical outcomes in severe COVID-19 (iScience (2022) 25(11), (S2589004222015449), (10.1016/j.isci.2022.105272))
Erben, Y., Prudencio, M., Marquez, C. P., Jansen-West, K. R., Heckman, M. G., White, L. J., Dunmore, J. A., Cook, C. N., Lilley, M. T., Qosja, N., Song, Y., Al Shaikh, R. H., Daughrity, L. M., Bartfield, J. L., Day, G. S., Oskarsson, B., Nicholson, K. A., Wszolek, Z. K., Hoyne, J. B., Gendron, T. F., & 2 others , Apr 19 2024, In: iScience. 27, 4, 109501.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases
Calliari, A., Daughrity, L. M., Albagli, E. A., Castellanos Otero, P., Yue, M., Jansen-West, K., Islam, N. N., Caulfield, T., Rawlinson, B., DeTure, M., Cook, C., Graff-Radford, N. R., Day, G. S., Boeve, B. F., Knopman, D. S., Petersen, R. C., Josephs, K. A., Oskarsson, B., Gitler, A. D., Dickson, D. W., & 5 others , Dec 2024, In: Molecular neurodegeneration. 19, 1, 29.Research output: Contribution to journal › Letter › peer-review
Open Access -
Mis-spliced transcripts generate de novo proteins in TDP-43–related Als/FTD
Seddighi, S., Qi, Y. A., Brown, A. L., Wilkins, O. G., Bereda, C., Belair, C., Zhang, Y. J., Prudencio, M., Keuss, M. J., Khandeshi, A., Pickles, S., Kargbo-Hill, S. E., Hawrot, J., Ramos, D. M., Yuan, H., Roberts, J., Sacramento, E. K., Shah, S. I., Nalls, M. A., Colón-Mercado, J. M., & 31 others , 2024, In: Science translational medicine. 16, 734, eadg7162.Research output: Contribution to journal › Article › peer-review
Open Access